The kappa opioid receptor agonist SA14867 has antinociceptive and weak sedative effects in models of acute and chronic pain

European Journal of Pharmacology

Volumn 671, Issue 1-3, 2011, Pages 53-60

  Tsukahara Ohsumi, Yaeko ^a,b   Tsuji, Fumio ^a   Niwa, Masashi ^a   Hata, Taeko ^c   Narita, Minoru ^b   Suzuki, Tsutomu ^b   Sasano, Minoru ^a   Aono, Hiroyuki ^a  

^a SANTEN PHARMACEUTICAL CO LTD   (Japan)

^b HOSHI UNIVERSITY   (Japan)

^c KINKI UNIVERSITY   (Japan)

Author keywords

Arthritis induced hyperalgesia model; Kappa opioid receptor agonist; SA14867; Sciatic nerve ligation model; Specific alternation of rhythm in environmental temperature (SART) stressed model

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; 3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMINE; ASIMADOLINE; BACLOFEN; KAPPA OPIATE RECEPTOR AGONIST; MORPHINE; NALOXONE; SA 14867; UNCLASSIFIED DRUG;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CHRONIC PAIN; CONTROLLED STUDY; DRUG EFFECT; ENVIRONMENTAL TEMPERATURE; HYPERALGESIA; MALE; MOUSE; NEUROPATHIC PAIN; NONHUMAN; PAIN; PAIN THRESHOLD; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SEDATION;

ACETAMIDES; ACUTE PAIN; ANALGESICS; ANIMALS; ARTHRITIS; CHRONIC PAIN; DISEASE MODELS, ANIMAL; HYPERALGESIA; HYPNOTICS AND SEDATIVES; LIGATION; MALE; MICE; MORPHINE; NEURALGIA; PAIN THRESHOLD; PYRROLIDINES; RECEPTORS, OPIOID, KAPPA; SCIATIC NERVE; STRESS, PHYSIOLOGICAL; TARTRATES; TEMPERATURE; THIAZOLES;

EID: 80455122660     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.09.169     Document Type: Article

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