Mitochondrial gene transfer ribonucleic acid (tRNA)(Leu(UUR)) 3243 and tRNA(Lys) 8344 mutations and diabetes mellitus in Korea

Journal of Clinical Endocrinology and Metabolism

Volumn 82, Issue 2, 1997, Pages 372-374

  Lee, Hyun Chul ^a   Song, Young Duk ^a   Li, Hai Ri ^a   Park, Jum Ok ^a   Suh, Hyung Chan ^a   Lee, Eunjik ^a   Lim, Seungkil ^a   Kim, Kyungrae ^a   Huh, Kapbum ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFER RNA;

ADULT; AGED; AMINO ACID SEQUENCE; ARTICLE; DIABETES MELLITUS; FEMALE; GENE DELETION; GENE LOCATION; GENE MUTATION; GENE TRANSFER; HUMAN; KOREA; MAJOR CLINICAL STUDY; MALE; ORAL GLUCOSE TOLERANCE TEST; PERCEPTION DEAFNESS; PRIORITY JOURNAL; RECEPTOR GENE;

EID: 8044255246     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.82.2.3747     Document Type: Article

References (26)

1. Taylar SI. 1992 Molecular mechanisms of insulin resistance: lessons from patients with mutations in the insulin-receptor gene. Diabetes. 41:1473-1490.
2. Kadowaki T, Bevins CL, Cama A. 1988 Two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance. Science. 240:789-790.
3. Deleted in proof.
4. Froguel P, Vaxillaire M, Sun F. 1992 Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus. Nature. 356:162-164 (erratum, Nature. 357:607:1992).
5. Froguel P, Zoualin H, Vionnet N. 1993 Familial hyperglycemia due to mutations in glucokinase: definition of a subtype of diabetes mellitus. N Engl J Med. 328:697-702.
6. Eto K, Sakura H, Shimokawa K. 1993 Sequence variations of the glucokinase gene in Japanese subjects with NIDDM. Diabetes. 42:1133-1137.
7. Hager J, Hansen L, Vaisse C, et al. 1995 A missense mutation in the glucagon receptor gene is associated with noninsulin-dependent diabetes mellitus. Nat Genet. 9:299-304.
8. Hitman GA, Hawrami K, McCarthy NI, et al. 1995 insulin receptor substrate-1 gene mutations in NIDDM; implications for the study of polygenic disease. Diabetologia. 38:481-486.
9. Prochazka M, Lillioja S, Tait JF, et al. 1993 Linkage of chromosomal markers on 4q with a putative gene determining maximal insulin action in Pima Indians. Diabetes 42:514-519.
10. 3-adrenergic-receptor gene. N Engl J Med 333:343-347.
11. Ballinger SW, Shoffner JM, Hedaya EF. 1992 Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion. Nat Genet 1:11-15.
12. Shanske S, Moraes CT, Lombes A. 1990 Widespread tissue distribution of mitochondrial DNA deletions in Kearns-Sayre syndrome. Neurology. 40:24-28.
13. Reardon W, Ross RJM, Sweeney MG. 1992 Diabetes mellitus associated with a pathogenic point mutation in mitochondrial DNA. Lancet. 2:1376-1379.
14. Leu(UUR) mutation. Neurology. 43:1015-1020.
15. Leu(UUR) gene. FEBS Lett. 321:194-196.
16. Lys mutation. Diabetes Care. 17:1428-1432.
17. Otabe S, Sakura K, Shimokawa K, et al. 1994 The high prevalence of the diabetic patients with a mutation in the mitochondrial gene in Japan. J Clin Endocrinol Metab. 79:768-771.
18. Kadowaki T, Kadowaki H, Mori Y, et al. 1994 A subtype of diabetes mellitus associated with mutation of mitochondrial DNA. N Engl J Med. 330:962-968.
19. Leu(UUR) gene. Lancet. 341:1291-1292.
20. Oka Y, Katagiri H, Yazaki Y, Murase T, Kobayashi T. 1993 Mitochondrial gene mutation in islet-cell-antibody-positive-patients who were initially non-insulin dependent diabetes. Lancet. 342:527-528.
21. Leu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness. Nat Genet. 1:368-371.
22. Alcolado JC, Clark PM, Rees A, Hales CN. 1994 Insulin resistance and impaired glucose tolerance. Lancet. 344:1293-1294.
23. Sue CM, Holmes-Walker DJ, Morris JGL, Boyages SC, Crimmins DS, Byrne E. 1993 Mitochondrial gene mutations and diabetes mellitus. Lancet. 341:437-438.
24. Kanamori A, Tanaka K, Unezawa S, Matoba K, Fujita Y, Yajima Y. 1994 Insulin resistance in mitochondrial gene mutation. Diabetes Care. 17:778-779.
25. Larsson NG, Tulinius MH, Holme E, et al. 1992 Segregation and manifestations of the mtDNA tRNA(Lys) A→G(8344) mutation of myoclonus epilepsy and ragged red fibers (MERRF) syndrome. Am J Hum Genet. 51:1201-1212.
26. Moraes CT, Schon EA, Dimauro S, Miranda AF. 1989 Heteroplasmy of mitochondrial genomes in clonal cultures from patients with Kearns-Sayre syndrome. Biochem Biophys Res Commun. 160:765.