Allogeneic vs autologous stem cell transplantation vs chemotherapy in patients with acute myeloid leukemia in first remission: The BGMT 87 study

Leukemia

Volumn 10, Issue 12, 1996, Pages 1874-1882

  Reiffers, J ^a   Stoppa, A M ^c   Attal, M ^d   Michallet, M ^b   Marit, C ^a   Blaise, D ^c   Huguet, F ^d   Corront, B ^b   Cony Makhoul, P ^a   Gastaut, J A ^c   Laurent, G ^d   Molina, L ^b   Braustet, A ^a   Maraninchi, D ^c   Pris, J ^d   Hollard, D ^b   Faberes, C ^a  

^a HAUT LÉVÊQUE HOSPITAL   (France)

^b CHU La Tronche and University   (France)

^c INSTITUT PAOLI CALMETTES   (France)

^d CHU PURPAN   (France)

Author keywords

Acute myeloid leukemia; Bone marrow transplantation; Intensive chemotherapy; Prognostic factors

Indexed keywords

CYTARABINE; DAUNORUBICIN; MERCAPTOPURINE; METHOTREXATE;

ACUTE GRANULOCYTIC LEUKEMIA; ADOLESCENT; ADULT; ALLOTRANSPLANTATION; APLASIA; ARTICLE; AUTOTRANSPLANTATION; CANCER SURVIVAL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HLA MATCHING; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; LEUKEMIA REMISSION; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; ORAL DRUG ADMINISTRATION; PNEUMONIA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEPTICEMIA; SIBLING; STEM CELL TRANSPLANTATION; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 8044252807     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Foon KA, Gale RP. Therapy of acute myelogenous leukemia. Blood Rev 1992; 6: 15-25.
2. Mayer RJ. Current chemotherapeutic treatment approaches to the management of previously untreated adults with de novo acute myelogenous leukemia. Semin Oncol 1987; 14: 384-396.
3. Bortin MM, Horowitz MM, Rowling S, Rimm AA, Sobocinski KA, Zhang MJ, Gale RP. Progress report from the International Bone Marrow Transplant Registry. Bone Marrow Transplant 1993; 12: 97-104.
4. Corin NC, Aegerter P, Auvert B, Meloni G, Goldstone AH, Burnett A, Carella A, Korbling M, Herve P, Maraninchi D, Lowenberg R, Verdonck LF, de Planque M, Hermans J, Helbig W, Porcellini A, Rizzoli V, Alesandrino EP, Franklin IM, Reiffers J, Colleselli P, Goldman JM. Autologous bone marrow transplantation for acute myelocytic leukemia in first remission: a European survey; the role of marrow purging. Blood 1990; 75: 1606-1614.
5. Wolff SN, Herzig RH, Fay JW, Philips GL, Lazarus HM, Flexner JM, Stein RS, Greer JP, Cooper B, Herzig CP. High-dose cytarabine and daunorubicin as consolidation therapy for acute myeloid leukemia in first remission: long-term follow-up and results. J Clin Oncol 1989; 7: 1260-1267.
6. Cassileth PA, Lynch E, Hines JD, Oken MM, Mazza JJ, Bennett JM, McGlave PB, Edelstein M, Harrington DP, O'Connell M. Varying intensity of post-remission therapy in acute myeloid leukemia. Blood 1992; 79: 1924-1930.
7. Mayer RJ, Davis RB, Schiffer CA, Berg DT, Powell BL, Schulman P, Omura GA, Moore JO, McIntyre OR, Frei III E. Intensive post-remission chemotherapy in adults with myeloid leukemia. New Engl J Meet 1994; 331: 896-903.
8. Geller RB, Burke PJ, Karp JE, Humphrey RL, Braine HG, Tucker RW, Fox MG, Zahurak M, Morrell L, Hall KL. A two-step timed sequential treatment for acute meylocytic leukemia. Blood 1989; 74: 1499-1989.
9. Appelbaum FR. Fischer LD, Thomas D and the Seattle Marrow Transplant Team. Chemotherapy vs marrow transplantation for adults with acute non-lymphocytic leukemia: a five-year followup. Blood 1988; 72: 179-184.
10. Willemze R, Fibbe WE, Kluin-Nelemans JC, Falfenburg JHF, Richel DJ, Peters WG, den Ottolander GJ, Brand A, Zwaan FE. Bone marrow transplantation or chemotherapy as post-remission treatment of adult acute myelogenous leukemia. Ann Hematol 1991; 62: 59-63.
11. Conde E, Iriondo A, Rayon C, Richard C, Fanjul E. Garijo J, Hermosa V, Coma A, Bello C, Carerra D, Baro J, Zubizarreta A. Allogeneic bone marrow transplantation versus intensification chemotherapy for acute myelogenous leukaemia in first remission: a prospective controlled trial. Br J Haematol 1988; 68: 219-226.
12. Zander AR, Keating M, Dicke K, Dixon D, Pierce S, Jagannath S, Peters L, Horwitz L, Cockerill K, Spitzer G, Vellekoop L, , Kantarjian H, Walters R, McCredie K, Freireich EJ. A comparison of marrow transplantation with chemotherapy for adults with acute leukemia of poor prognosis in first complete remission. J Clin Oncol 1988; 6: 1548-1557.
13. Powles RL, Clink HM, Bandini G, Watson JG, Spence D, Jameson B, Kay HEM, Morgenstern G, Hedley D, Lumley H, Lawson D, Barrett A, Lawler S, McElwain TJ. The place of bone marrow transplantation in acute myelogenous leukaemia. Lancet 1980; 1: 1047-1050.
14. Archimbaud E, Thomas X, Michallet M, Jaubert J, Troncy J, Guyotat D, Fiere D. Prospective genetically randomized comparison between intensive post-induction chemotherapy and bone marrow transplantation in adults with newly diagnosed acute myeloid leukemia. J Clin Oncol 1994; 12: 262-267.
15. Champlin RE, Ho WG, Gale RP, Winston D, Selch M, Mitsuyasu R, Lenarsky C, Elashoff R, Zighelboim J, Feig SA. Treatment of acute myelogenous leukemia. Ann Intern Med 1985; 102: 285-291.
16. Geller RB, Saral R, Karp JE, Santos GW, Burke PJ. Cure of acute myelocytic leukemia in adults: a reality. Leukemia 1990; 4: 313-315.
17. Reiffers J, Gaspard MH, Maraninchi D, Michallet M, Marit G, Stoppa AM, Corront B, David B, Gastaut JA, Sotto JJ, Broustet A, Carcassonne Y, Hollard D. Comparison of allogeneic or autologous bone marrow transplantation and chemotherapy in patients with acute myeloid leukaemia in first remission: a prospective controlled trial. Br J Haematol 1989; 72: 57-63.
18. Zittoun RA, Mandelli F, Willemze R, De Witte T, Labar B, Resegotti L, Leoni F, Damasio E, Visani G, Papa G, Caronia F, Hayat M, Stryckrnans P, Rotoli B, Leoni P, Peetermans ME, Dardenne M, Luce Vegna M, Concetta Petti M, Solbu G, Suciu S, for the European Organization for Research and Treatment of Cancer (EORTC) and the Gruppo Italiano Malattie Ematologiche Maligne Dell'Adulto (GIMEMA) Leukemia Cooperative Groups. Autologous or allogeneic bone marrow transplantation compared with intensive chemotherapy in acute myelogenous leukemia. New Engl J Med 1995; 332: 217-223.
19. Butturini A, Gale RP. Chemotherapy versus transplantation in acute leukaemia. Br J Haematol 1989; 72: 1-8.
20. Suciu S. The value of BMT in AML patients in first remission. A statistician's view-point. Ann Hematol 1991; 62: 41-44.
21. Dastugue N, Payen C, Lafage-Pochitaloff M, Bernard P, Leroux D, Huguet-Rigal F, Stoppa AM, Marit G, Molina L, Michallet M, Maraninchi D, Attal M, Reiffers J for the BGMT group. Prognostic significance of karyotype in de novo adult acute myeloid leukemia. Leukemia 1995; 9: 1491-1498.
22. Samuels BL, Larson RA, Le Beau MM, Daly KM, Bitter MA, Vardiman JW, Barker CM, Rowley JD, Colomb HM. Specific chromosomal abnormalities in acute non-lymphocytic leukemia correlate with drug susceptibility in vivo. Leukemia 1988; 2: 79-83.
23. Champlin R, Ho W, Winston D, Decker R, Greenberg P, Burnison M, Holly FE, Gale RP. Treatment of adults with acute myelogenous leukemia: prospective evaluation of high-dose cytarabine in consolidation chemotherapy and with bone marrow transplantation. Semin Oncol 1987; 14: 1-6.
24. Reiffers J, Vezon G, Bernard P, Sarrat A, Chevaleyre J, Marit G, David G, Bouzgarrou R, Broustet A. Stem cell apheresis in patients with acute non-lymphocytic leukemia. Plasma Therapy Transf Technol 1988; 9: 115-118.
25. Kaplan EL, Meier P. Non-parametric estimation from incomplete observations. J Am Stat Ass 1958; 53: 457-481.
26. Cox DR. Regression models and life tables. J Roy Stat Soc Series B 1972; 34: 187-220.
27. Reiffers J, Stoppa AM, Attal M, Michallet M. Is there a place for blood stem cell transplantation for the younger adult patient with acute myelogenous leukemia? J Clin Oncol 1994; 12: 1100 (letter).
28. Gorin NC, Dicke F, Lowenberg B. High-dose therapy for acute myelocytic leukemia treatment strategy: what is the choice? Ann Oncol 1993; 4 (Suppl. 1): 59-80.
29. Clift RA, Buckner CD, Appelbaum FR, Bearman SI, Petersen FB, Fisher LD, Anasetti C, Beatty P, Bensinger WI, Doney K, Hill RS, McDonald CB, Martin P, Sanders J, Singer J, Stewart P, Sullivan KM, Witherspoon R, Storb R, Hansen JA, Thomas ED. Allogeneic marrow transplantation in patients with acute myeloid leukemia in first remission: a randomized trial of two irradiation regimens. Blood 1990; 76: 1867-1871.
30. Snyder DS, Chao NJ, Amylon MD, Taguchi J, Long GD, Negrin RS, Nademanee AP, O'Donnell MR, Schmidt GM, Stein AS, Parker PM, Smith EP, Stepan DE, Molina A, Lipsett JA, Hoppe RT, Niland IC, Dagis AC, Wong RM, Forman SJ, Blume KG. Fractionated total body irradiation and high-dose etoposide as a preparatory regimen for bone marrow transplantation for 99 patients with acute leukemia in first complete remission. Blood 1993; 82: 2920-2928.
31. Brochstein JA, Kernan NA, Groshen S, Cirrincione C, Shank B, Emanuel D, Laver J, O'Reilly RJ. Allogeneic bone marrow transplantation after hyperfractionated total body irradiation and cyclophosphamide in children with acute leukemia. New Engl J Med 1987; 317: 1618-1624.
32. McGlave PB, Haake RJ, Bostrom BC, Brunning R, Hurd DD, Kim TH, Nesbit ME, Vercellotti GM, Weisdorf D, Woods WG, Ramsay NKC, Kersey JH. Allogeneic bone marrow transplantation for acute non-lymphocytic leukemia in first remission. Blood 1988; 72: 1512-1517.
33. Working Party on Leukemia. European Group for Bone Marrow Transplantation. Allogeneic bone marrow transplantation for leukemia in Europe. Lancet 1988; 1: 1379-1382.
34. Horowitz MM, Przepiorka D, Champlin RE, Gale RP, Gratwohl A, Herzig RH, Prentice HG, Rimm AA, Ringden O, Bortin MM. Should HLA-identical sibling bone marrow transplants for leukemia be restricted to large centers? Blood 1992; 79: 2771-2774.
35. Bacigalupo A, Van Lint MT, Occhini D, Gualandi F, Lamparelli T, Sogno G, Tedone E, Frassoni F, Tong J, Marmont AM. Increased risk of leukemia relapse with high-dose cyclosporin A after allogeneic marrow transplantation for acute leukaemia. Blood 1991; 77: 1423-1428.
36. Ferrant A, Doyen C, Delannoy D, Cornu G, Martiat P, Latinne D, De Bruyere M, Bosly A, Michaux JL, Sokal G. Allogeneic or autologous bone marrow transplantation for acute non-lymphocytic leukemia in first remission, Bone Marrow Transplant 1991; 7: 303-309.
37. Lowenberg B, Verdonck LJ, Dekker W, Willemze R, Zwaan FE, De Planque M, Abels J, Sonneveld P, Van der Lelie J, Goudsmit R, Van Putten WLJ, Sizoo W, Hogenbekk A, De Gast GC. Autologous bone marrow transplantation in acute myeloid leukemia in first remission: results of a Dutch prospective study. J Clin Oncol 1990; 8: 287-294.
38. Mitus J, Miller KB, Schenkein DP, Ryan HF, Parsons SK, Wheeler C, Antin JH. Improved survival for patients with acute myelogenous leukemia. J Clin Oncol 1995; 13: 560-569.
39. Antin JH. Graft-versus-leukemia: no longer an epiphenomenon. Blood 1993; 82: 2273-2277.
40. Atkinson KA, Horowitz MM, Sobocinski KA, Rimm AA, Bortin MM, Gale RP. Therapy decisions in leukemia. Bone Marrow Transplant 1992; 9: 5-10.
41. Berman E, Little C, Gee T, O'Reilly R, Clarkson B. Reasons that patients with acute myelogenous leukemia do not undergo allogeneic bone marrow transplantation. New Engl J Med 1992; 16: 156-160.
42. Degos S, Dombret H, Chomienne C, Daniel MT, Miclea JM, Chastang C, Castaigne S, Fenaux P. All-trans retinoic acid as a differentiating agent in the treatment of acute promyelocytic leukemia. Blood 1995; 85: 2643-2653.
43. Clift AR, Buckner CD, Appelbaum FR, Schoch G, Petersen FB, Bensinger WI, Sanders J, Sullivan KM, Storb R, Singer J, Hansen JA, Thomas ED. Allogeneic marrow transplantation during untreated first relapse of acute myeloid leukemia. J Clin Oncol 1992; 10: 1723-1729.
44. Dufoir T, Saux MC, Guessard S, Terraza B, Marit G, Foulon P, Reiffers J. Comparative cost of allogeneic or autologous bone marrow transplantation and chemotherapy in patients with acute myeloid leukemia in first remission. Bone Marrow Transplant 1992; 10: 323-329.