메뉴 건너뛰기




Volumn 137, Issue 12, 1996, Pages 5537-5543

The 69-84 amino acid region of the parathyroid hormone molecule is essential for the interaction of the hormone with the binding sites with carboxyl-terminal specificity

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; PARATHYROID HORMONE; PARATHYROID HORMONE DERIVATIVE; PARATHYROID HORMONE[1-34];

EID: 8044252188     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.12.8940381     Document Type: Article
Times cited : (40)

References (46)
  • 2
    • 0014900421 scopus 로고
    • Bovine parathyroid hormone: Amino acid sequence
    • Brewer Jr HB, Ronan R 1970 Bovine parathyroid hormone: amino acid sequence. Proc Natl Acad Sci USA 67:1862-1869
    • (1970) Proc Natl Acad Sci USA , vol.67 , pp. 1862-1869
    • Brewer Jr., H.B.1    Ronan, R.2
  • 4
    • 0021238774 scopus 로고
    • Gene encoding parathyroid Hormone. Nucleotide sequence of the rat gene and deduced amino acid sequence of rat preproparathyroid hormone
    • Heinrich G, Kronenberg HM, Potts Jr JT, Habener JF 1984 Gene encoding parathyroid Hormone. Nucleotide sequence of the rat gene and deduced amino acid sequence of rat preproparathyroid hormone. J Biol Chem 259:3320-3329
    • (1984) J Biol Chem , vol.259 , pp. 3320-3329
    • Heinrich, G.1    Kronenberg, H.M.2    Potts Jr., J.T.3    Habener, J.F.4
  • 5
    • 0003415897 scopus 로고
    • Biochemical mechanisms of parathyroid hormone action
    • Bilexikian JP, Levine MA, Marcus R (eds) Raven Press, New York
    • Coleman DT, Fitzpatrick LA, Bilezikian JP 1994 Biochemical mechanisms of parathyroid hormone action In: Bilexikian JP, Levine MA, Marcus R (eds) The Parathyroids. Raven Press, New York, pp 239-258
    • (1994) The Parathyroids , pp. 239-258
    • Coleman, D.T.1    Fitzpatrick, L.A.2    Bilezikian, J.P.3
  • 7
    • 0026466174 scopus 로고
    • The carboxy-terminus of parathyroid hormone is essential for hormone processing and secretion
    • Lim SK, Gardella TJ, Baba H, Nussbaum SR, Kronenberg HM 1992 The carboxy-terminus of parathyroid hormone is essential for hormone processing and secretion. Endocrinology 131:2325-2330
    • (1992) Endocrinology , vol.131 , pp. 2325-2330
    • Lim, S.K.1    Gardella, T.J.2    Baba, H.3    Nussbaum, S.R.4    Kronenberg, H.M.5
  • 9
    • 0026023864 scopus 로고
    • Acute administration of intact parathyroid hormone but not its amino-terminal fragment stimulates volume of pancreatic secretion
    • El-Shahawy MA, Fadda GZ, Wisner Jr JR, Renner IG, Omachi H, Massry SG 1991 Acute administration of intact parathyroid hormone but not its amino-terminal fragment stimulates volume of pancreatic secretion. Nephron 57:69-74
    • (1991) Nephron , vol.57 , pp. 69-74
    • El-Shahawy, M.A.1    Fadda, G.Z.2    Wisner Jr., J.R.3    Renner, I.G.4    Omachi, H.5    Massry, S.G.6
  • 11
    • 0023783680 scopus 로고
    • Effect of parathyroid hormone on random migration of human polymorphonuclear leukocytes
    • Doherty CC, Labelle P, Collins JF, Brautbar N, Massry SG 1988 Effect of parathyroid hormone on random migration of human polymorphonuclear leukocytes. Am J Nephrol 8:212-219
    • (1988) Am J Nephrol , vol.8 , pp. 212-219
    • Doherty, C.C.1    Labelle, P.2    Collins, J.F.3    Brautbar, N.4    Massry, S.G.5
  • 12
  • 13
    • 0024577007 scopus 로고
    • Human parathyroid hormone carboxyterminal peptide (53-84) stimulates alkaline phosphatase activity in dexamethasone-treated rat osteosarcoma cells in vitro
    • Murray TM, Rao LG, Muzaftar SA, Ly H 1989 Human parathyroid hormone carboxyterminal peptide (53-84) stimulates alkaline phosphatase activity in dexamethasone-treated rat osteosarcoma cells in vitro. Endocrinology 124:1097-1099
    • (1989) Endocrinology , vol.124 , pp. 1097-1099
    • Murray, T.M.1    Rao, L.G.2    Muzaftar, S.A.3    Ly, H.4
  • 14
    • 0025998522 scopus 로고
    • Dexamethasone-treated ROS 17/2.8 rat osteosarcoma cells are responsive to human carboxylterminal parathyroid hormone peptide hPTH(53-84): Stimulation of alkaline phosphatase
    • Murray TM, Rao LG, Muzaffar SA 1991 Dexamethasone-treated ROS 17/2.8 rat osteosarcoma cells are responsive to human carboxylterminal parathyroid hormone peptide hPTH(53-84): Stimulation of alkaline phosphatase. Calcif Tissue Int 49:120-123
    • (1991) Calcif Tissue Int , vol.49 , pp. 120-123
    • Murray, T.M.1    Rao, L.G.2    Muzaffar, S.A.3
  • 15
    • 0027195327 scopus 로고
    • Individual and combined effects of intact PTH, amino-terminal, and a series of truncated carboxyl-terminal PTH fragments on alkaline phosphatase activity in dexamethasone-treated rat osteoblastic osteosarcoma cells, ROS 17/2.8
    • Nakamoto C, Baba H, Fukase M, Nakajima K, Kimura T, Sakakibara S, Fujita T, Chihara K 1993 Individual and combined effects of intact PTH, amino-terminal, and a series of truncated carboxyl-terminal PTH fragments on alkaline phosphatase activity in dexamethasone-treated rat osteoblastic osteosarcoma cells, ROS 17/2.8. Acta Endocrinol 128:367-372
    • (1993) Acta Endocrinol , vol.128 , pp. 367-372
    • Nakamoto, C.1    Baba, H.2    Fukase, M.3    Nakajima, K.4    Kimura, T.5    Sakakibara, S.6    Fujita, T.7    Chihara, K.8
  • 16
    • 0028194885 scopus 로고
    • Carboxyl-terminal parathyroid hormone peptide (53-84) elevates alkaline phosphatase and osteocalcin mRNA levels in SaOS-2 cells
    • Sutherland MK, Rao LG, Wylie JN, Gupta A, Ly H, Sodek J, Murray TM 1994 Carboxyl-terminal parathyroid hormone peptide (53-84) elevates alkaline phosphatase and osteocalcin mRNA levels in SaOS-2 cells. J Bone Miner Res 9:453-458
    • (1994) J Bone Miner Res , vol.9 , pp. 453-458
    • Sutherland, M.K.1    Rao, L.G.2    Wylie, J.N.3    Gupta, A.4    Ly, H.5    Sodek, J.6    Murray, T.M.7
  • 18
    • 0025733569 scopus 로고
    • In vitro response of neonatal condylar cartilage to simultaneous exposure to the parathyroid hormone fragments 1-34, 28-48, and 53-84 hPTH
    • Silbermann M, Shurtz-Swirski R, Lewinson D, Shenzer P, Mayer H 1991 In vitro response of neonatal condylar cartilage to simultaneous exposure to the parathyroid hormone fragments 1-34, 28-48, and 53-84 hPTH. Calcif Tissue Int 48:260-266
    • (1991) Calcif Tissue Int , vol.48 , pp. 260-266
    • Silbermann, M.1    Shurtz-Swirski, R.2    Lewinson, D.3    Shenzer, P.4    Mayer, H.5
  • 19
    • 0020739434 scopus 로고
    • Binding of radioiodinated bovine parathyroid hormone-(1-84) to canine renal cortical membranes
    • Rizzoli RE, Murray TM, Marx SJ, Aurbach GD 1983 Binding of radioiodinated bovine parathyroid hormone-(1-84) to canine renal cortical membranes. Endocrinology 112:1303-1312
    • (1983) Endocrinology , vol.112 , pp. 1303-1312
    • Rizzoli, R.E.1    Murray, T.M.2    Marx, S.J.3    Aurbach, G.D.4
  • 20
    • 0020608513 scopus 로고
    • Binding of radioiodinated parathyroid hormone to cloned bone cells
    • Rizzoli RE, Somerman M, Murray TM, Aurbach GD 1983 Binding of radioiodinated parathyroid hormone to cloned bone cells. Endocrinology 113:1832-1838
    • (1983) Endocrinology , vol.113 , pp. 1832-1838
    • Rizzoli, R.E.1    Somerman, M.2    Murray, T.M.3    Aurbach, G.D.4
  • 21
    • 0022377086 scopus 로고
    • Binding of intact parathyroid hormone to chicken renal plasma membranes: Evidence for a second binding site with carboxyl-terminal specificity
    • McKee MD, Murray TM 1985 Binding of intact parathyroid hormone to chicken renal plasma membranes: evidence for a second binding site with carboxyl-terminal specificity. Endocrinology 117:1930-1939
    • (1985) Endocrinology , vol.117 , pp. 1930-1939
    • McKee, M.D.1    Murray, T.M.2
  • 22
    • 0021961202 scopus 로고
    • Binding of intact parathyroid hormone to rat osteosarcoma cells: Major contribution of binding sites for the carboxyl-terminal region of the hormone
    • Rao LG, Murray TM 1985 Binding of intact parathyroid hormone to rat osteosarcoma cells: Major contribution of binding sites for the carboxyl-terminal region of the hormone. Endocrinology 117:1632-1638
    • (1985) Endocrinology , vol.117 , pp. 1632-1638
    • Rao, L.G.1    Murray, T.M.2
  • 24
    • 0026598246 scopus 로고
    • Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: A single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium
    • Abou-Samra AB, Jüppner H, Force T, Freeman MW, Kong XF, Schipani E, Urena P, Richards J, Bonventre JV, Potts Jr JT, Kronenberg HM, Segre GV 1992 Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: A single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium. Proc Natl Acad Sci USA 89:2732-2736
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 2732-2736
    • Abou-Samra, A.B.1    Jüppner, H.2    Force, T.3    Freeman, M.W.4    Kong, X.F.5    Schipani, E.6    Urena, P.7    Richards, J.8    Bonventre, J.V.9    Potts Jr., J.T.10    Kronenberg, H.M.11    Segre, G.V.12
  • 26
    • 0027982237 scopus 로고
    • Generation and characterization of human kidney cell lines stably expressing recombinant human PTH/PTHrP receptor: Lack of interaction with a c-terminal human PTH peptide
    • Pines M, Adams AE, Stueckle S, Bessalle R, Rashti-Behar V, Chorev M, Rosenblatt M, Suva LJ 1994 Generation and characterization of human kidney cell lines stably expressing recombinant human PTH/PTHrP receptor: lack of interaction with a c-terminal human PTH peptide. Endocrinology 135:1713-1716
    • (1994) Endocrinology , vol.135 , pp. 1713-1716
    • Pines, M.1    Adams, A.E.2    Stueckle, S.3    Bessalle, R.4    Rashti-Behar, V.5    Chorev, M.6    Rosenblatt, M.7    Suva, L.J.8
  • 27
    • 0028812647 scopus 로고
    • Characterization of a novel parathyroid hormone (PTH) receptor with specificity for the carboxyl-terminal region of PTH-(1-84)
    • Inomata N, Akiyama M, Kubota N, Jüppner H 1995 Characterization of a novel parathyroid hormone (PTH) receptor with specificity for the carboxyl-terminal region of PTH-(1-84). Endocrinology 136:4732-4740
    • (1995) Endocrinology , vol.136 , pp. 4732-4740
    • Inomata, N.1    Akiyama, M.2    Kubota, N.3    Jüppner, H.4
  • 28
    • 0002391789 scopus 로고
    • Structure-function analysis of parathyroid hormone and parathyroid hormone-related protein
    • Bilezikian JP, Levine MA, Marcus R (eds) Raven Press, New York
    • Chorev M, Rosenblatt M 1994 Structure-function analysis of parathyroid hormone and parathyroid hormone-related protein. In: Bilezikian JP, Levine MA, Marcus R (eds) The Parathyroids. Raven Press, New York, pp 139-156
    • (1994) The Parathyroids , pp. 139-156
    • Chorev, M.1    Rosenblatt, M.2
  • 31
    • 0023074923 scopus 로고
    • Human preproparathyroid hormone synthesized in Escherichia coli is transported to the surface of the bacterial inner membrane but not processed to the mature hormone
    • Born W, Freeman M, Hendy GN, Rapoport A, Rich A, Ports Jr JT, Kronenberg HM 1987 Human preproparathyroid hormone synthesized in Escherichia coli is transported to the surface of the bacterial inner membrane but not processed to the mature hormone. Mol Endocrinol 1:5-14
    • (1987) Mol Endocrinol , vol.1 , pp. 5-14
    • Born, W.1    Freeman, M.2    Hendy, G.N.3    Rapoport, A.4    Rich, A.5    Ports Jr., J.T.6    Kronenberg, H.M.7
  • 33
    • 0018926608 scopus 로고
    • Parathyroid hormone-responsive clonal cell lines from rat osteosarcoma
    • Majeska RJ, Rodan SB, Rodan GA 1980 Parathyroid hormone-responsive clonal cell lines from rat osteosarcoma. Endocrinology 107:1494-1503
    • (1980) Endocrinology , vol.107 , pp. 1494-1503
    • Majeska, R.J.1    Rodan, S.B.2    Rodan, G.A.3
  • 34
    • 0023906324 scopus 로고
    • Characterization and agonist-induced down-regulation of parathyroid hormone receptors in clonal rat osteosarcoma cells
    • Yamamoto I, Shigeno C, Potts Jr JT, Segre GV 1988 Characterization and agonist-induced down-regulation of parathyroid hormone receptors in clonal rat osteosarcoma cells. Endocrinology 122:1208-1217
    • (1988) Endocrinology , vol.122 , pp. 1208-1217
    • Yamamoto, I.1    Shigeno, C.2    Potts Jr., J.T.3    Segre, G.V.4
  • 37
    • 0019312938 scopus 로고
    • A theoretical study of the structure of parathyroid hormone
    • Zull JE, Lev NB 1980 A theoretical study of the structure of parathyroid hormone. Proc Natl Acad Sci USA 77:3791-3795
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 3791-3795
    • Zull, J.E.1    Lev, N.B.2
  • 38
    • 0018759453 scopus 로고
    • The degradation of proparathormone and parathormone by parathyroid and liver cathepsin B
    • MacGregor RR, Hamilton JW, Kent GN, Shofstall RE, Cohn DV 1979 The degradation of proparathormone and parathormone by parathyroid and liver cathepsin B. J Biol Chem 254:4428-4433
    • (1979) J Biol Chem , vol.254 , pp. 4428-4433
    • MacGregor, R.R.1    Hamilton, J.W.2    Kent, G.N.3    Shofstall, R.E.4    Cohn, D.V.5
  • 39
    • 0020593981 scopus 로고
    • Cleavage of parathyroid hormone to the 1-34 and 35-84 fragments by cathepsin D-like activity in bovine parathyroid gland extracts
    • Hamilton JW, Jilka RL, MacGregor RR 1983 Cleavage of parathyroid hormone to the 1-34 and 35-84 fragments by cathepsin D-like activity in bovine parathyroid gland extracts. Endocrinology 113:285-292
    • (1983) Endocrinology , vol.113 , pp. 285-292
    • Hamilton, J.W.1    Jilka, R.L.2    MacGregor, R.R.3
  • 40
    • 0019411684 scopus 로고
    • Metabolism of parathyroid hormone by isolated rat Kupffer cells and hepatocytes
    • Segre GV, Perkins AS, Witters LA, Potts Jr JT 1981 Metabolism of parathyroid hormone by isolated rat Kupffer cells and hepatocytes. J Clin Invest 67:449-457
    • (1981) J Clin Invest , vol.67 , pp. 449-457
    • Segre, G.V.1    Perkins, A.S.2    Witters, L.A.3    Potts Jr., J.T.4
  • 41
    • 0023009774 scopus 로고
    • Production of biologically active fragments of parathyroid hormone by isolated Kupffer cells
    • Pillai S, Zull JE 1986 Production of biologically active fragments of parathyroid hormone by isolated Kupffer cells. J Biol Chem 261:14919-14923
    • (1986) J Biol Chem , vol.261 , pp. 14919-14923
    • Pillai, S.1    Zull, J.E.2
  • 42
    • 0019888625 scopus 로고
    • Specific cleavage of bovine parathyroid hormone catalyzed by an endopeptidase from bovine kidney
    • Botti Jr RE, Heath E, Frelinger AL, Chuang J, Roos BA, Zull JE 1981 Specific cleavage of bovine parathyroid hormone catalyzed by an endopeptidase from bovine kidney. J Biol Chem 256:11483-11488
    • (1981) J Biol Chem , vol.256 , pp. 11483-11488
    • Botti Jr., R.E.1    Heath, E.2    Frelinger, A.L.3    Chuang, J.4    Roos, B.A.5    Zull, J.E.6
  • 43
    • 0020652340 scopus 로고
    • Identification of an ATP-activated endopeptidase from rat kidney which catalyzes cleavage of parathyroid hormone to fragments identical to those produced in the rat kidney in vivo
    • Botti Jr RE, Zull JE 1983 Identification of an ATP-activated endopeptidase from rat kidney which catalyzes cleavage of parathyroid hormone to fragments identical to those produced in the rat kidney in vivo. Endocrinology 112:393-395
    • (1983) Endocrinology , vol.112 , pp. 393-395
    • Botti Jr., R.E.1    Zull, J.E.2
  • 44
    • 0022917349 scopus 로고
    • Degrading activity for human parathyroid hormone [PTH-(1-84)] in rat osteoblast-like osteosarcoma cell line UMR106
    • Yamaguchi T, Baba H, Fukase M, Kinoshita Y, Fujimi T, Fujita T 1986 Degrading activity for human parathyroid hormone [PTH-(1-84)] in rat osteoblast-like osteosarcoma cell line UMR106. Biochem Biophys Res Commun 141:762-768
    • (1986) Biochem Biophys Res Commun , vol.141 , pp. 762-768
    • Yamaguchi, T.1    Baba, H.2    Fukase, M.3    Kinoshita, Y.4    Fujimi, T.5    Fujita, T.6
  • 45
    • 0018614624 scopus 로고
    • Distribution of circulating immunoreactive components of parathyroid hormone in normal subjects and in patients with primary and secondary hyperparathyroidism: The role of the kidney and of the serum calcium concentration
    • Dambacher MA, Fischer JA, Hunziker WH, Born W, Moran J, Roth HR, Delvin EE, Glorieux FH 1979 Distribution of circulating immunoreactive components of parathyroid hormone in normal subjects and in patients with primary and secondary hyperparathyroidism: the role of the kidney and of the serum calcium concentration. Clin Sci 57:435-443
    • (1979) Clin Sci , vol.57 , pp. 435-443
    • Dambacher, M.A.1    Fischer, J.A.2    Hunziker, W.H.3    Born, W.4    Moran, J.5    Roth, H.R.6    Delvin, E.E.7    Glorieux, F.H.8
  • 46
    • 0022969901 scopus 로고
    • Influence of serum Ca concentration on circulating molecular forms of PTH in three species
    • D'Amour P, Labelle F, Lecavalier L, Plourde V, Harvey D 1986 Influence of serum Ca concentration on circulating molecular forms of PTH in three species. Am J Physiol 251:E680-E687
    • (1986) Am J Physiol , vol.251
    • D'Amour, P.1    Labelle, F.2    Lecavalier, L.3    Plourde, V.4    Harvey, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.