The protective effect of β-carotene and retinol on ventilatory function in an asbestos-exposed cohort

American Journal of Respiratory and Critical Care Medicine

Volumn 155, Issue 3, 1997, Pages 1066-1071

  Chuwers, Patricia ^b   Barnhart, Scott ^b   Blanc, Paul ^b   Brodkin, Carl A ^b   Cullen, Mark ^b   Kelly, Thomas ^b   Keogh, James ^b   Omenn, Gilbert ^b   Williams, James ^b   Balmes, John R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ASBESTOS; BETA CAROTENE; RETINOL PALMITATE;

ADULT; AGED; ARTICLE; ASBESTOSIS; CIGARETTE SMOKING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG EFFICACY; FORCED EXPIRATORY VOLUME; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG VENTILATION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; ORAL DRUG ADMINISTRATION; PREDICTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

EID: 8044245456     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.155.3.9116988     Document Type: Article

References (27)

1. Becklake, M. R. 1976. Asbestos-related diseases of the lungs and other organs: their epidemiology and implications for clinical practice. Am. Rev. Respir. Dis. 114:187-227.
2. Camilli, A. E., B. Burrows, R. J. Knudson, S. K. Lyle, and M. D. Lebowitz. 1987. Longitudinal changes in forced expiratory volume in one second in adults: effects of smoking and smoking cessation. Am. Rev. Respir. Dis. 135:794-799.
3. Xu, X., D. W. Dockery, J. H. Ware, F. E. Speizer, and B. G. Ferris, Jr. 1992. Effects of cigarette smoking on rate of loss of pulmonary function in adults: a longitudinal assessment. Am. Rev. Respir. Dis. 146:1345-1348.
4. Tockman, M. S., M. J. Khoury, and B. H. Cohen. 1986. Milk drinking and possible protection of the respiratory epithelium. J. Chron. Dis. 39:207-209.
5. Morabia, A., A. Sorenson, S. K. Kumanyika, H. Abbey, B. H. Cohen, and E. Chee. 1989. Vitamin A, smoking, and airway obstruction. Am. Rev. Respir. Dis. 140:1312-1316.
6. Morabia, A., M. J. S. Menkes, G. W. Comstock, and M. S. Tockman. 1990. Serum retinol and airway obstruction. Am. J. Epidemiol. 132: 77-82.
7. Shahar, E., A R. Folsom, S. L. Melnick, M. S. Tockman, G. W. Comstock, T. Shimakawa, M. W. Higgins, P. D. Sorlie, and M. Szklo. 1994. Does dietary vitamin A protect against airway obstruction? Am. J. Respir. Crit. Care Med. 150:978-982.
8. Omenn, G. S., G. Goodman, M. Thornquist, J. Grizzle, L. Rosenstock, S. Barnhart, J. Balmes, M. G. Cherniack, M. R. Cullen, A. Glass, J. Keogh, F. Meyskens, Jr., B. Valanis, and J. Williams, Jr. 1994. The β-carotene and retinol efficacy trial (CARET) for chemoprevention of lung cancer in high risk populations: smokers and asbestos-exposed workers. Cancer Res. 54S:2038s-2043s.
9. Brodkin, C. A, S. Barnhart, G. Anderson, H. Checkoway, G. S. Omenn, and L. Rosenstock. 1993. Correlation between respiratory symptoms and pulmonary function in asbestos-exposed workers. Am. Rev. Respir. Dis. 148:32-37.
10. American Thoracic Society. 1987. Standardization of spirometry. Am. Rev. Respir. Dis. 136:1285-1298.
11. Goodman, G. E., B. J. Metch, and G. S. Omenn. 1994. The effect of long term β-carotene and vitamin A administration on serum concentrations of α-tocopherol. Cancer Epidemiol. Biomarkers Prev. 3:429-432.
12. Goodman, G., I. Gylys-Colwell, G. Anderson, M. Kestin, G. Omenn, and CARET Co-investigators. 1994. Association between food frequency questionnaire estimates and serum concentrations of β-carotene, retinol, retinyl palmitate, and α-tocopherol among participants in the CARET lung cancer chemoprevention trial. Controlled Clin. Trials 15(3S):111S.
13. International Labour Office. 1980. Guidelines for the Use of the ILO International Classification of Radiographs of Pneumoconioses, revised ed. ILO, Geneva, Switzerland.
14. SAS Institute Inc. 1988. SAS/STAT User's Guide: Release 6.03 Edition. Cary, NC.
15. Crapo, R. O., A. H. Morris, and R. M. Gardner. 1981. Reference spirometric values using technique and equipment that meet ATS recommendations. Am. Rev. Respir. Dis. 123:659-664.
16. Eisen, E. A., L. C. Oliver, D. C. Christiani, J. M. Robins, and D. H. Wegman. 1985. Effects of spirometry standards in two occupational cohorts. Am. Rev. Respir. Dis. 132:120-124.
17. Eisen, E. A., D. W. Dockery, F. E. Speizer, M. E. Fay, and B. G. Ferris, Jr. 1987. The association between health status and the performance of excessively variable spirometry tests in a population-based study in U.S. cities. Am. Rev. Respir. Dis. 136:1371-1376.
18. Becklake, M. R. 1990. Epidemiology of spirometric test failure [Editorial]. Br. J. Ind. Med. 47:73-74.
19. Omenn, G. S., G. E. Goodman, M. D. Thornquist, L. Rosenstock, S. Barnhart, I. Gylys-Colwell, B. Metch, and B. Lund. 1993. The Carotene and Retinol Efficacy Trial (CARET) to prevent lung cancer in high-risk populations: pilot study with asbestos-exposed workers. Cancer Epidemiol. Biomarkers Prev. 2:389-396.
20. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study Group. 1994. The effect of vitamin E and beta-carotene on the incidence of lung cancer and other cancers in male smokers. N. Engl. J. Med. 330:1029-1035.
21. Omenn, G. S., G. E. Goodman, M. D. Thornquist, J. Balmes, M. R. Cullen, A. Glass, J. P. Keogh, F. L. Meyskens, B. Valanis, J. H. Williams, Jr., S. Barnhart, and S. Hammar. 1996. Effects of a combination of beta-carotene and vitamin A on lung cancer and cardiovascular disease. N. Engl. J. Med. 334:1150-1155.
22. Chytil, F. The lungs and vitamin A. 1992. Am. J. Physiol. 262:L517-L527.
23. Jetten, A. M., T. M. Volberg, C. Nervi, and M. D. George. 1990. Positive and negative regulation of proliferation and differentiation in tracheobronchial epithelial cells. Am. Rev. Respir. Dis. 142:S36-S39.
24. Burton, G. W., and K. U. Ingold. 1984. β-carotene: an unusual type of lipid antioxidant. Science 224:569-573.
25. Burney, P. 1995. The origins of obstructive airways disease: a role for diet? Am. J. Respir. Crit. Care Med. 151:1292-1293.
26. Knekt, P., A. Aromaa, J. Maatela, R. K. Aaran, T. Nikkari, M. Hakama, T. Hakulinen, R. Peto, and L. Teppo. 1990. Serum vitamin A and subsequent risk of cancer: cancer incidence follow-up of the Finnish mobile clinic health examination survey. Am. J. Epidemiol. 132:857-870.
27. Goodman, G. E., G. Anderson, M. Kestin, B. Metch, G. S. Omenn, and CARET Co-investigators. 1996. The association between participant characteristics and serum concentrations of β-carotene, retinol, retinyl palmitate, and α-tocopherol among participants in the Carotene and Retinol Efficacy Trial (CARET) for prevention of lung cancer. Cancer Epidemiol. Biomarkers Prev. 5:815-821.