Allogeneic bone marrow transplantation versus chemotherapy in high-risk childhood acute lymphoblastic leukaemia in first remission

British Journal of Haematology

Volumn 96, Issue 2, 1997, Pages 387-394

  Uderzo, Cornelio ^a   Valsecchi, Maria Grazia ^a   Balduzzi, Adriana ^a   Dini, Giorgio ^b   Miniero, Roberto ^c   Locatelli, Franco ^d   Rondelli, Roberto ^e   Pession, Andrea ^e   Arcese, William ^f   Bacigalupo, Andrea ^g   Polchi, Paola ^h   Andolina, Marino ⁱ   Messina, Chiara ^j   Conter, Valentino ^a   Aricó, Maurizio ^d   Galimberti, Stefania ^a   Masera, Giuseppe ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b G GASLINI INSTITUTE   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

^d UNIVERSITY OF PAVIA   (Italy)

^e UNIVERSITY OF BOLOGNA   (Italy)

^f Haematology Institute   (Italy)

^g UNIVERSITY OF GENOA   (Italy)

^h Haematalogy Department   (Italy)

ⁱ UNIVERSITY OF TRIESTE   (Italy)

^j UNIVERSITY OF PADOVA   (Italy)

more..

Author keywords

chemotherapy; childhood; high risk ALL; marrow transplant

Indexed keywords

BUSULFAN; CYCLOPHOSPHAMIDE; CYTARABINE; ETOPOSIDE; THIOTEPA; VINCRISTINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ALLOGENIC BONE MARROW TRANSPLANTATION; ARTICLE; CANCER CHEMOTHERAPY; CHILD; CHILDHOOD LEUKEMIA; CONTROLLED STUDY; FEMALE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

EID: 8044242350     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1997.d01-2033.x     Document Type: Article

References (29)

1. Aricò, M., Basso, G., Mandelli, F., Rizzari, C., Colella, R., Barisone, E., Zanesco, L., Rondelli, R., Pession, A. & Masera, G. (1995) Good steroid response in vivo predicts a favourable outcome in children with T-cell acute lymphoblastic leukaemia. Cancer, 75, 1684-1693.
2. Balduzzi, A., Gooley, T., Anasetti, C., Sanders, J.E., Martin, P.J., Petersdorf, E.W., Appelbaum, F.R., Buckner, C.D., Matthews, D., Storb, R., Sullivan, K.M. & Hansen, J.A. (1995) unrelated donor marrow transplantation in children. Blood, 86, 3247-3256.
3. Barrett, A.J., Horowitz, M.M., Gale, R.P., Biggs, J.C., Camitta, B.M., Dicke, K.A., Gluckman, E., Good, R.A., Herzig, R.H., Lee, M.B., Marmont, A.M., Masaoka, T., Ramsay, N.K.C., Rimm, A.A., Speck, B., Zwaan, F.E. & Bortin, M.M. (1989) Marrow transplantation for acute lymphoblastic leukemia: factors affecting relapse and survival. Blood, 74, 862-871.
4. Bearman, S.I., Appelbaum, F.R., Buckner, C.D., Petersen, F.B., Fisher, L.D., Clift, R.A. & Thomas, E.D. (1988) Regimen related toxicity in patients undergoing bone marrow transplantation. Journal of Clinical Oncology 6, 1562-1568.
5. Bordigoni, P., Vernant, J.P., Souillet, G., Gluckman, E., Marininchi, D., Milpied, N., Fischer, A., Benz Lemoine, E., Jouet, J.P. & Reiffers, J. (1989) Allogeneic bone marrow transplantation for children with acute lymphoblastic leukaemia in first remission: a cooperative study of the group d'étude de la Greffe de Moelle Osseuse. Journal of Clinical Oncology, 7, 747-753.
6. Chessells, J.M., Bailey, C., Wheeler, K. & Richards, S.M. (1992) Bone marrow transplantation for high-risk childhood lymphoblastic leukaemia in first remission: experience in MRC UKALL X. Lancet, 340, 565-568.
7. Conter, V., Aricò, M., Valsecchi, M.G., Rizzari, C., Testi, A.M., Messina, C., Mori, P.G., Miniero, R., Colella, R., Basso, G., Rondelli, G., Pession, A. & Masera, G. (1995a) Extended intrathecal methotrexate may replace cranial irradiation for prevention of CNS relapse in children with intermediate risk acute lymphoblastic leukaemia treated with Berlin-Frankfurt-Münster based intensive chemotherapy. Journal of Clinical Oncology 13, 2497-2502.
8. Conter, V, Rizzari, C., Aricò, M., Basso, G., Cantù-Rajnoldi, A., Colella, R., Dibenedetto, S.P. Di Tullio, M.T., Messina, C., Miniero, R., Mori, P.G., Pession, A., Rondelli, R., Silvestri, D., Testi, A.M., Valsecchi, M.G. & Masera, G. (1995b) Preliminary results of the AIEOP '91 study for childhood acute lymphoblastic leukaemia (ALL). Medical and Pediatric Oncology 17, 283.
9. Cox. D.R. (1972) Regression models and life tables with discussion. Journal of Royal Statistics Society, 34, 187-220.
10. Crist, W., Shuster, J., Look, T., Borowitz, M., Behm, F., Bowman, P., Frankel, L., Pullen, J., Krance, R. & Steuber, P. (1992) Current results of studies of immunophenotype. age and leukocyte-based therapy for children with acute lymphoblastic leukaemia. Leukaemia, 6, 162-166.
11. Deeg, H.J., Storb, R., Thomas, E.D., Flournoy, N., Kennedy, M.S., Banaji, M., Appelbaum, F.R., Bensinger, W.I., Buckner, C.D., Clift, R.A., Doney, K., Fefer, A., McGuffin, R., Sanders, J.E., Singer, J., Stewart, P., Sullivan, K.M. & Witherspoon, R.P. (1985) Cyclosporine as prophylaxis for graft-versus-host disease: a randomized study in patients undergoing marrow transplantation for acute nonlymphoblastic leukemia. Blood, 65, 1325-1334.
12. Fletcher, J.A., Lynch, E.A., Kimball, V.M., Donnelly, M., Tantravahi, R. & Sallan, S.E. (1991) Translocation 9:22 is associated with extremely poor prognosis in intensively treated children with acute lymphoblastic leukemia. Blood, 77, 435-439.
13. Forman, S.J. & Zaia, J.A. (1994) Treatment and prevention of cytomegalovirus pneumonia after bone marrow transplantation: where do we stand? Blood, 83, 2392-2398.
14. Gaynon, P.S., Bleyer, W.A., Steinherz, P.G., Finklestein, J.Z., Littman, P., Miller, D.R., Reaman, G., Sather, H. & Hammond, G.D. (1990) Day 7 marrow response and outcome for children with acute lymphoblastic leukaemia and unfavourable presenting features. Medical Pediatric Oncology, 18, 273-279.
15. Horowitz, M.M. & Bortin, M.M. (1993) Results of bone marrow transplant from human leukocyte antigen-identical sibling donors for treatment of childhood leukemias: a report from the International Bone Marrow Registry. American Journal of Pediatric Hematology and Oncology, 15, 56-64.
16. Horowitz, M.M., Messerer, D., Hoelzer, D., Gale, R.P., Neiss, A., Atkinson, K., Barrett, J., Buchner, T., Freund, M., Heil, G., Hiddemann, W., Kolb, H.J., Loffler, H. Marmaont, A.M., Maschmeyer, G., Rimm, A.A., Rozman, C., Sobocinski, K.A., Speck, B., Thiel, E., Weisdorf, D.J., Zwaan, F.E. & Bortin, M.M. (1991) Chemotherapy compared with bone marrow transplantation for adults with acute lymphoblastic leukaemia in first remission. Annals of Internal Medicine, 115, 13-18.
17. Marubini, E. & Valsccchi, M.G. (1995) Analysing Survival data from Clinical Trials and Observational Studies, Chapter 7. pp. 223-265. and Chapter 10. pp. 331-363. John Wiley & Sons, Chichester.
18. Reiter, A., Schrappe, M., Wolf-Dieter, L., Hiddemann, W., Sauter, S., Henze, G., Zimmermann, M., Lampert, F., Havers, W., Niethammer, D., Odenwald, E., Ritter, J., Mann, G., Welte, K., Gadner, H. & Reim, H. (1994) Chemotherapy in 998 unselected childhood acute lymphoblastic leukemia patients: results and conclusions of the multicenter trial ALL-BFM 86. Blood, 84, 3122-3133.
19. Rivera, G.K., Pinkel, D., Simone, J.V., Hancock, M.L. & Crist, W.M. (1993) Treatment of acute lymphoblastic leukemia: 1993: 30 years' experience at St. Jude Children's Research Hospital. New England Journal of Medicine, 329, 1289-1295.
20. Santos, G.W., Tutschka, P.J., Brookmeyer, R., Saral, R., Beschorner, W.E., Bias, W.B., Braine, H.G., Burns, W.H., Elfenbein, G.J., Kaizer, H., Mellits, D., Sensenbrenner, L.L., Stuart, R.K. & Yeager, A.M. (1983) Marrow transplantation for acute non-lymphocytic leukemia after treatment with busulphan and cyclophosphamide. New England Journal of Medicine, 309, 1347-1353.
21. Saarinen, U.M., Mellander, L., Nysom, K., Ringden, O., Schroeder, H., Glomstein, A. & Gustafsson, G. (1996) Allogeneic bone marrow transplantation in first remission for children with very high-risk acute lymphoblastic leukaemia: a retrospective case-control study in the Nordic countries. Bone Msrrow Transplantation, 17, 357-363.
22. Sebban, C., Lepage, E., Vernant, J.P., Gluckman, E., Attal, M., Reiffers, J., Sutton, L., Racadot, E., Michallet, M., Maraninchi, D., Dreyfus, F. & Fiere, D. (1994) Allogeneic bone marrow transplantation in adult acute lymphoblastic leukemia in first complete remission: a comparative study. Journal of Clinical Oncology, 12, 2580-2587.
23. Snyder, U.S., Negrin, R.S., O'Donnell, M.R., Chao, N.J., Amylon, M.D., Long, G.D., Nademanee, A.P., Stein, A.S., Parker, P.M., Smith, E.P., Somlo, G., Margolin, K., Molina, A., Stepan, D.E., Lipsett, J.A., Hoppe, R.T., Slovak, M.L., Niland, J.C., Dagis, A.C., Wong, R.M., Forman, S.J. & Blume, K.G. (1994) Fractionated total-body irradiation and high-dose etoposide as a preparatory regimen for bone marrow transplantation for 94 patients with chronic myelogenous leukemia in chronic phase. Blood, 84, 1672-1679.
24. Uderzo, C., Rondelli, R., Dini, G., Dallorso, S., Messina, C., Miniero, R., Locatelli, F., De Manzini, A., Pession, A., Balduzzi, A., Locasciulli, A. & Masera, G. (1995a) High-dose vincristine, fractionated total body irradiation and cyclophosphamide as conditioning regimen in allogeneic and autologous bone marrow transplantation for childhood acute lymphoblastic leukaemia in second remission: a 7-year Italian multicentre study. British Journal of Haematology, 89, 790-797.
25. Uderzo, C., Valsecchi, M.G., Dini, G., Miniero, R., Locatelli, F., Pession, A., Arcese, W., Baciagalupo, A., Polchi, P., Andolina, M., Porta, F., Messina, C., Colombini, A., Silvestri, D., Bozzato, N., Testa, M., Balduzzi, A. & Masera, G. (1995b) Allogeneic BMT (AlloBMT) as compared to chemotherapy (Chemo) in high-risk childhood acute lymphoblastic leukemia (HR-ALL) in first complete remission: a case control analysis of the Italian Pediatric Hematology Oncology Association (AIEOP) and the Italian Bone Marrow Transplantation Group (GITMO). Blood, 10, (Suppl. 1). 1521, 383a.
26. Vecchi, V. Aricò, M., Basso, G., Ceci, A., Madon, E., Mandelli, F., Masera, G., Massimo, L., Pession, A., Zanesco, L. & Paolucci, G. (1995) Risk-directed therapy for childhood acute lymphoblastic leukaemia. Cancer, 72, 2517-2524.
27. Von Bueltzingsloewen, A., Belanger, R., Perreault, C., Bonny, Y., Roy, D.C., Boileau, J., Kassis, J., Lavallee, R., Lacombe, M. & Gyger, M. (1993) Allogeneic hone marrow transplantation following busulfan-cyclophosphamide with or without etoposide conditioning regimen for patients with acute lymphoblastic leukaemia. British Journal of Haematolagy, 85, 706-713.
28. Von Bueltzingsloewen, A., Eperou-Bourdeau, H., Souillet, G., Demeocq, F., Mechinaud-Lacroix, E. Michel, G., Sadoun, A., Bernaudin, F., Cornu, G., Donadieu, J., Ruble, H., Rorlich, P., Lacour, B., Gluckman, E. & Bordigoni, P (1995) Allogeneic bone marrow transplantation following a busulfan-based conditioning rogimen in young children with acute lymphoblastic leukaemia: a Cooperative Study of the Société Francaise de Greffe de Moelle. Bone Marrow Transplantation, 16, 521-527.
29. Wingard, J.R., Piantadosi, S., Santos, G.W., Saral, R., Vriesendorp, H.M., Yeager, J., Burns, W.H., Ambinder, R.F., Braine, H.G., Elfenbein, G., Jones, R.J., Kaizer, H., Stratford May, W., Rowley, S.D., Sensenbrenner, L.L., Stuart, R.K., Tutschka, P.J.. Vogelsang, G.B., Wagner, J.E., Beschorner, W.E., Brookmeyer, R. & Farmer, E.R. (1990) Allogeneic bone marrow transplantation for patients with high-risk acute lymphoblastic leukaemia. Journal of Clinical Oncology, 8, 820-830.