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Volumn 75, Issue 8, 1997, Pages 1173-1184

Presence of exon 5-deleted oestrogen receptor in human breast cancer: Functional analysis and clinical significance

Author keywords

Breast neoplasm; Exon; Oestrogen receptor; Polymerase chain reaction; Transcription

Indexed keywords

ESTROGEN RECEPTOR; MESSENGER RNA; MONOCLONAL ANTIBODY; PROGESTERONE RECEPTOR;

EID: 8044242323     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1997.202     Document Type: Article
Times cited : (45)

References (48)
  • 1
    • 0023393713 scopus 로고
    • A water soluble, monitorable peptide and protein crosslinking agent
    • Aldwin L and Nitecki DE (1987) A water soluble, monitorable peptide and protein crosslinking agent. Anal Biochem 164: 494-501
    • (1987) Anal Biochem , vol.164 , pp. 494-501
    • Aldwin, L.1    Nitecki, D.E.2
  • 2
    • 0027405070 scopus 로고
    • Phosphorylation of the human oestrogen receptor; identification of a phosphorylation site required for trans-activation
    • Ali S, Metzger D, Bornerl J-M and Chambon P (1993a) Phosphorylation of the human oestrogen receptor; identification of a phosphorylation site required for trans-activation. EMBO J 12; 1153-1160
    • (1993) EMBO J , vol.12 , pp. 1153-1160
    • Ali, S.1    Metzger, D.2    Bornerl, J.-M.3    Chambon, P.4
  • 3
    • 0027894195 scopus 로고
    • Production and characterisation of monoclonal antibodies recognising defined regions of the human oestrogen receptor
    • Ali S, Lutz Y, Bellocq J-P. Chenard-Neu M-P, Rouyer N and Metzger D (1993b) Production and characterisation of monoclonal antibodies recognising defined regions of the human oestrogen receptor. Hybridoma 12; 391-405
    • (1993) Hybridoma , vol.12 , pp. 391-405
    • Ali, S.1    Lutz, Y.2    Bellocq, J.-P.3    Chenard-Neu, M.-P.4    Rouyer, N.5    Metzger, D.6
  • 4
    • 37049101880 scopus 로고
    • Solid phase peptide synthesis using N. fluorenyl methocarboxycarbonyl amino-acid penta fluorophenyl esters
    • Atherton E and Sheppard RC (1985) Solid phase peptide synthesis using N. fluorenyl methocarboxycarbonyl amino-acid penta fluorophenyl esters. J Chem Soc Chem Commun 15; 165-166
    • (1985) J Chem Soc Chem Commun , vol.15 , pp. 165-166
    • Atherton, E.1    Sheppard, R.C.2
  • 7
    • 0025062215 scopus 로고
    • Role of the two activating domains of the estrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen
    • Berry M, Metzger D and Chambon P (1990) Role of the two activating domains of the estrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen. EMBO J 9: 2811-2818
    • (1990) EMBO J , vol.9 , pp. 2811-2818
    • Berry, M.1    Metzger, D.2    Chambon, P.3
  • 8
    • 0027318488 scopus 로고
    • An immunohistochemical study of the long-term effects of androgen administration on female-to-male transsexual breast: A comparison with normal female breast and male breast showing gynaecomastia
    • Burgess HE and Shousha S (1993) An immunohistochemical study of the long-term effects of androgen administration on female-to-male transsexual breast: a comparison with normal female breast and male breast showing gynaecomastia. J Pathol 170; 37-43
    • (1993) J Pathol , vol.170 , pp. 37-43
    • Burgess, H.E.1    Shousha, S.2
  • 9
    • 0028795855 scopus 로고
    • Exon 5 deletion variant estrogen receptor messenger RNA in relation to tamoxifen resistance and progesterone receptor/pS2 status in human breast cancer
    • Daffada AI. Johnston SRD, Smith IE, Detre S, King N and Dowsett M (1995) Exon 5 deletion variant estrogen receptor messenger RNA in relation to tamoxifen resistance and progesterone receptor/pS2 status in human breast cancer. Cancer Res 55; 288-293
    • (1995) Cancer Res , vol.55 , pp. 288-293
    • Daffada, A.I.1    Johnston, S.R.D.2    Smith, I.E.3    Detre, S.4    King, N.5    Dowsett, M.6
  • 10
    • 0026780789 scopus 로고
    • Characterisation of estrogen receptor variant mRNAs from human breast cancer
    • Dotzlaw H, Alkhalaf M and Murphy I.C (1992) Characterisation of estrogen receptor variant mRNAs from human breast cancer. Mol Endocrinol 6; 773-785
    • (1992) Mol Endocrinol , vol.6 , pp. 773-785
    • Dotzlaw, H.1    Alkhalaf, M.2    Murphy, I.C.3
  • 12
    • 0025988196 scopus 로고
    • Binding analysis of the estrogen receptor to its specific DNA target site in human breast cancer
    • Foster BD, Cavener DR and Parl FF (1991) Binding analysis of the estrogen receptor to its specific DNA target site in human breast cancer. Cancer Res 51; 3405-3410
    • (1991) Cancer Res , vol.51 , pp. 3405-3410
    • Foster, B.D.1    Cavener, D.R.2    Parl, F.F.3
  • 13
    • 0027931198 scopus 로고
    • Estrogen receptor mutagenesis and hormone resistance
    • Fuqua Saw (1994) Estrogen receptor mutagenesis and hormone resistance. Cancer 74: 1026-1029
    • (1994) Cancer , vol.74 , pp. 1026-1029
    • Fuqua, S.A.W.1
  • 16
    • 0019739585 scopus 로고
    • Preparation of monoclonal antibodies: Strategies and procedures
    • Galfre G and Milstein C (1987) Preparation of monoclonal antibodies: strategies and procedures. Methods Enzymol 73: 3-36
    • (1987) Methods Enzymol , vol.73 , pp. 3-36
    • Galfre, G.1    Milstein, C.2
  • 17
    • 0023254634 scopus 로고
    • Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor
    • Green S and Chambon P (1987) Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor. Nature 325: 75-78
    • (1987) Nature , vol.325 , pp. 75-78
    • Green, S.1    Chambon, P.2
  • 19
  • 20
    • 0028137227 scopus 로고
    • How do breast cancers become hormone resistant?
    • Horwitz KB (1994) How do breast cancers become hormone resistant? J Steroid Biochem Mol Biol 49; 295-302
    • (1994) J Steroid Biochem Mol Biol , vol.49 , pp. 295-302
    • Horwitz, K.B.1
  • 21
    • 0025103048 scopus 로고
    • A cleavage method which minimizes side reactions following Finoc solid phase peptide synthesis
    • King DS, Fields CG and Fields GB (1990) A cleavage method which minimizes side reactions following Finoc solid phase peptide synthesis. Int Peptide Protein Res 36; 255-266
    • (1990) Int Peptide Protein Res , vol.36 , pp. 255-266
    • King, D.S.1    Fields, C.G.2    Fields, G.B.3
  • 22
    • 0022720813 scopus 로고
    • The chicken oestrogen receptor sequence: Homology with v-erbA and the human oestrogen and glucocorticoid receptors
    • Krust A, Green S, Argos P, Kumar V, Walter P, Bornert J-M and Chambon P (1986) The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors. EMBO J 5; 891-897
    • (1986) EMBO J , vol.5 , pp. 891-897
    • Krust, A.1    Green, S.2    Argos, P.3    Kumar, V.4    Walter, P.5    Bornert, J.-M.6    Chambon, P.7
  • 23
    • 0022773520 scopus 로고
    • Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor
    • Kumar V, Green S, Staub A and Chambon P (1986) Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor. EMBO J 5: 2231-2236
    • (1986) EMBO J , vol.5 , pp. 2231-2236
    • Kumar, V.1    Green, S.2    Staub, A.3    Chambon, P.4
  • 26
    • 0024318808 scopus 로고
    • Identification of two trans-activation domains in the mouse oestrogen receptor
    • Lees JA, Fawell SE and Parker MG (1989) Identification of two trans-activation domains in the mouse oestrogen receptor. Nucleic Acids Res 17; 5477-5488
    • (1989) Nucleic Acids Res , vol.17 , pp. 5477-5488
    • Lees, J.A.1    Fawell, S.E.2    Parker, M.G.3
  • 28
    • 0027403293 scopus 로고
    • Estrogen receptor variant and hypertension in women
    • Lehrer S, Rabin J, Kalir T and Schachter BS (1992) Estrogen receptor variant and hypertension in women. Hypertension 21: 439-441
    • (1992) Hypertension , vol.21 , pp. 439-441
    • Lehrer, S.1    Rabin, J.2    Kalir, T.3    Schachter, B.S.4
  • 30
    • 0018219234 scopus 로고
    • Hormone receptors: Their role in predicting prognosis and response to endocrine therapy
    • McGuire WL (1978) Hormone receptors: their role in predicting prognosis and response to endocrine therapy. Semin Oncol 5: 428-433
    • (1978) Semin Oncol , vol.5 , pp. 428-433
    • McGuire, W.L.1
  • 31
    • 0025789867 scopus 로고
    • Estrogen receptor variants in clinical breast Cancer
    • McGuire WL, Chamness GC and Fugua SAW (1991) Estrogen receptor variants in clinical breast Cancer. Mol Endocrinol 5: 1571-1577
    • (1991) Mol Endocrinol , vol.5 , pp. 1571-1577
    • McGuire, W.L.1    Chamness, G.C.2    Fugua, S.A.W.3
  • 32
    • 0028901040 scopus 로고
    • Characterization of the amino-terminal transcriptional activation Function of the human estrogen receptor in animal and yeast cells
    • Metzger D, Ali S, Bornert JM and Chambon P (1995) Characterization of the amino-terminal transcriptional activation Function of the human estrogen receptor in animal and yeast cells. J Biol Chem 270; 9535-9542
    • (1995) J Biol Chem , vol.270 , pp. 9535-9542
    • Metzger, D.1    Ali, S.2    Bornert, J.M.3    Chambon, P.4
  • 33
    • 0029058152 scopus 로고
    • The carboxy-terminal F domain of the human estrogen receptor; role in the transcriptional activity of the receptor and the effectiveness of antiestrogens as estrogen antagonists
    • Montano MM, Muller V, Trobaugh A and Katzenellenbogen BS (1995) The carboxy-terminal F domain of the human estrogen receptor; role in the transcriptional activity of the receptor and the effectiveness of antiestrogens as estrogen antagonists. Mol Endocrinol 9: 814-825
    • (1995) Mol Endocrinol , vol.9 , pp. 814-825
    • Montano, M.M.1    Muller, V.2    Trobaugh, A.3    Katzenellenbogen, B.S.4
  • 34
    • 0023199405 scopus 로고
    • Computer aided design and physiological testing of lutenisíng hormone-releasing hormone analogue for 'adjuvant free' immunocastration
    • Morrison CA, Fishleigh RV, Ward DJ and Robson B (1987) Computer aided design and physiological testing of lutenisíng hormone-releasing hormone analogue for 'adjuvant free' immunocastration. FEBS Lett 214: 65-70
    • (1987) FEBS Lett , vol.214 , pp. 65-70
    • Morrison, C.A.1    Fishleigh, R.V.2    Ward, D.J.3    Robson, B.4
  • 35
    • 0025699486 scopus 로고
    • Estrogen receptor variants in human breast cancer
    • Murphy LC (1990) Estrogen receptor variants in human breast cancer. Mol Cell Endocrinol 74: C83-C86
    • (1990) Mol Cell Endocrinol , vol.74
    • Murphy, L.C.1
  • 36
    • 0024119654 scopus 로고
    • Genomic organisation of the human oestrogen receptor gene
    • Ponglikitmongkol M, Green S and Chambon P (1988) Genomic organisation of the human oestrogen receptor gene. EMBO J 7: 3385-3388
    • (1988) EMBO J , vol.7 , pp. 3385-3388
    • Ponglikitmongkol, M.1    Green, S.2    Chambon, P.3
  • 37
    • 0026747130 scopus 로고
    • Prognostic significance of progesterone receptor levels in estrogen receptor-positive patients with metastatic breast cancer treated with tamoxifen: Results of a prospective Southwest Oncology Group study
    • Ravdin PM, Green S, Dorr TM, McGuire WL. Fabian C, Pugh RP, Carter RD, Rivkin SE, Borst JR, Belt RJ, Metch B and Osborne CK (1992) Prognostic significance of progesterone receptor levels in estrogen receptor-positive patients with metastatic breast cancer treated with tamoxifen: results of a prospective Southwest Oncology Group study. J Clin Oncol 10: 1284-1291
    • (1992) J Clin Oncol , vol.10 , pp. 1284-1291
    • Ravdin, P.M.1    Green, S.2    Dorr, T.M.3    McGuire, W.L.4    Fabian, C.5    Pugh, R.P.6    Carter, R.D.7    Rivkin, S.E.8    Borst, J.R.9    Belt, R.J.10    Metch, B.11    Osborne, C.K.12
  • 38
    • 0029923438 scopus 로고    scopus 로고
    • Effects of an exon 5 variant of the estrogen receptor in MCF-7 breast cancer cells
    • Rea D and Parker MG (1996) Effects of an exon 5 variant of the estrogen receptor in MCF-7 breast cancer cells. Cancer Res 56: 1556-1563
    • (1996) Cancer Res , vol.56 , pp. 1556-1563
    • Rea, D.1    Parker, M.G.2
  • 40
    • 0028078657 scopus 로고
    • Demonstration of oestrogen receptors in paraffin wax sections of breast carcinoma using the monoclonal antibody 1D5 and microwave oven processing
    • Sannino P and Shousha S (1994) Demonstration of oestrogen receptors in paraffin wax sections of breast carcinoma using the monoclonal antibody 1D5 and microwave oven processing. J Clin Pathol 47: 90-92
    • (1994) J Clin Pathol , vol.47 , pp. 90-92
    • Sannino, P.1    Shousha, S.2
  • 41
    • 0025737917 scopus 로고
    • Truncated forms of DNA binding estrogen receptors in human breast cancer
    • Scott GK, Kushner P, Vigne J-L and Benz CC (1991) Truncated forms of DNA binding estrogen receptors in human breast cancer. J Clin Invest 88: 700-706
    • (1991) J Clin Invest , vol.88 , pp. 700-706
    • Scott, G.K.1    Kushner, P.2    Vigne, J.-L.3    Benz, C.C.4
  • 42
    • 0026622048 scopus 로고
    • Role of estrogen receptor variants in the development of hormone resistance in breast cancer
    • Sluyser M (1994) Role of estrogen receptor variants in the development of hormone resistance in breast cancer. Clin Biochem 25; 407-414
    • (1994) Clin Biochem , vol.25 , pp. 407-414
    • Sluyser, M.1
  • 44
    • 0024317270 scopus 로고
    • The human estrogen receptor has two independent nonacidic transcriptional activation functions
    • Tora L, White J, Brou C, Tasset D, Webster N, Scheer E and Chambon P (1989a) The human estrogen receptor has two independent nonacidic transcriptional activation functions, Cell 59: 477-487
    • (1989) Cell , vol.59 , pp. 477-487
    • Tora, L.1    White, J.2    Brou, C.3    Tasset, D.4    Webster, N.5    Scheer, E.6    Chambon, P.7
  • 45
    • 0024440781 scopus 로고
    • The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties
    • Tora L, Mullick A, Metzger D, Ponglikitmongkol M, Park I and Chambon P (1989b) The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties. EMBO J 8: 1981-1986
    • (1989) EMBO J , vol.8 , pp. 1981-1986
    • Tora, L.1    Mullick, A.2    Metzger, D.3    Ponglikitmongkol, M.4    Park, I.5    Chambon, P.6
  • 46
    • 0025878197 scopus 로고
    • Identification of a dominant negative form of the human estrogen receptor
    • Wang Y and Miksicek RJ (1991) Identification of a dominant negative form of the human estrogen receptor. Mol Endocrinol 5: 1707-1715
    • (1991) Mol Endocrinol , vol.5 , pp. 1707-1715
    • Wang, Y.1    Miksicek, R.J.2
  • 47
    • 0023712331 scopus 로고
    • The hormone binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function
    • Webster NJG, Green S, Jin JR and Chambon P (1988) The hormone binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function Cell 54; 199-207
    • (1988) Cell , vol.54 , pp. 199-207
    • Webster, N.J.G.1    Green, S.2    Jin, J.R.3    Chambon, P.4
  • 48
    • 0027138874 scopus 로고
    • An exon 5 deletion variant of the estrogen receptor frequently co-expressed with wild-type estrogen receptor in human breast cancer
    • Zhang Q-X, Borg A and Fuqua SAW (1993) An exon 5 deletion variant of the estrogen receptor frequently co-expressed with wild-type estrogen receptor in human breast cancer. Cancer Res 53: 5882-5884
    • (1993) Cancer Res , vol.53 , pp. 5882-5884
    • Zhang, Q.-X.1    Borg, A.2    Fuqua, S.A.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.