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Volumn 16, Issue 1, 1996, Pages 1-8

Biochemical activity, pharmacokinetics and tolerability of tepoxalin, a cyclooxygenase/5-lipoxygenase inhibitor, in man

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM IONOPHORE; DRUG METABOLITE; LEUKOTRIENE B4; LIPOXYGENASE INHIBITOR; PROSTAGLANDIN SYNTHASE INHIBITOR; TEPOXALIN; THROMBOXANE; THROMBOXANE B2;

EID: 8044235832     PISSN: 02511649     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (14)

References (11)
  • 1
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    • Feuerstein G., Hallenbeck J.M. Leukotrienes in health and disease. FASEB J., 1, 186, 1986.
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    • Feuerstein, G.1    Hallenbeck, J.M.2
  • 4
    • 0000725690 scopus 로고
    • Topical and in vitro pharmacology of tepoxalin: A new dual cyclooxygenase (CO)/lipoxygenase (LO) inhibitor
    • Argentieri D.C. et al. Topical and in vitro pharmacology of tepoxalin: a new dual cyclooxygenase (CO)/lipoxygenase (LO) inhibitor. FASEB J., 2, A369, 1988.
    • (1988) FASEB J. , vol.2
    • Argentieri, D.C.1
  • 5
    • 0346389963 scopus 로고
    • Pulmonary and anti-inflammatory profile of tepoxalin, a dual cyclooxygenase (CO)/lipoxygenase (LO) inhibitor
    • Capetola R.J. et al. Pulmonary and anti-inflammatory profile of tepoxalin, a dual cyclooxygenase (CO)/lipoxygenase (LO) inhibitor. FASEB J., 2, A369, 1988.
    • (1988) FASEB J. , vol.2
    • Capetola, R.J.1
  • 6
    • 0001700112 scopus 로고
    • Tepdxalin (RWJ 20485) inhibits prostaglandin (PG) and leukotriene (LT) production in adjuvant arthritic rats and in dog knee joints challenged with sodium urate and immune complexes
    • Argentieri D.C., Anderson D.W., Ritchie D.M., Rosenthale M.E., Capetola R.J. Tepdxalin (RWJ 20485) inhibits prostaglandin (PG) and leukotriene (LT) production in adjuvant arthritic rats and in dog knee joints challenged with sodium urate and immune complexes. FASEB J., 4, A1142, 1990.
    • (1990) FASEB J. , vol.4
    • Argentieri, D.C.1    Anderson, D.W.2    Ritchie, D.M.3    Rosenthale, M.E.4    Capetola, R.J.5
  • 7
    • 0025740606 scopus 로고
    • Comparison of the ulcerogenic properties of tepoxalin with those of non-steroidal anti-inflammatory drugs (NSAIDs)
    • Wallace J. et al. Comparison of the ulcerogenic properties of tepoxalin with those of non-steroidal anti-inflammatory drugs (NSAIDs). Agents Actions, 34, 247, 1991.
    • (1991) Agents Actions , vol.34 , pp. 247
    • Wallace, J.1
  • 8
    • 0025159123 scopus 로고
    • R68070, a combined thromboxane-endoperoxide receptor antagonist and thromboxane synthase inhibitor, inhibits human platelet activation in vitro and in vivo: A comparison with aspirin
    • Hoet B. et al. R68070, a combined thromboxane-endoperoxide receptor antagonist and thromboxane synthase inhibitor, inhibits human platelet activation in vitro and in vivo: a comparison with aspirin. Blood, 75, 646, 1990.
    • (1990) Blood , vol.75 , pp. 646
    • Hoet, B.1
  • 9
    • 0028821025 scopus 로고
    • The effect of MK-0591 a novel 5-lipoxygenase activating protein inhibitor, on leukotriene biosynthesis and allergen-induced airway responses in asthmatic subjects in vivo
    • Diamant Z. et al. The effect of MK-0591 a novel 5-lipoxygenase activating protein inhibitor, on leukotriene biosynthesis and allergen-induced airway responses in asthmatic subjects in vivo. J. Allergy Clin. Immunol., 95, 43, 1995.
    • (1995) J. Allergy Clin. Immunol. , vol.95 , pp. 43
    • Diamant, Z.1
  • 10
    • 0011832289 scopus 로고
    • Cytokine modulation by lepoxalin - A dual cyclooxygenase (CO)/lipoxygenase (LO) inhibitor with potential antirheumatic activity
    • Vienna. Abstract P141
    • Ritchie D.M., Argentieri D.C., Lau C., Barbone A.G. Cytokine modulation by lepoxalin - a dual cyclooxygenase (CO)/lipoxygenase (LO) inhibitor with potential antirheumatic activity. Proceedings World Congr. Inflammation, Vienna. Abstract P141 (1993).
    • (1993) Proceedings World Congr. Inflammation
    • Ritchie, D.M.1    Argentieri, D.C.2    Lau, C.3    Barbone, A.G.4
  • 11
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    • kB dependent gene expression by tepoxalin, a dual inhibitor of cyclooxygenase and 5-lipoxygenase
    • kB dependent gene expression by tepoxalin, a dual inhibitor of cyclooxygenase and 5-lipoxygenase. J. Cell. Biochem., 57, 299, 1995.
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    • Syed, M.I.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.