Presurgical identification of epileptic foci with iodine-123 iomazenil SPET: Comparison with brain perfusion SPET and FDG PET

European Journal of Nuclear Medicine

Volumn 24, Issue 1, 1997, Pages 27-34

  Tanaka, Fumiko ^a   Yonekura, Yoshiharu ^b   Ikeda, Akio ^a   Terada, Kiyohito ^a   Mikuni, Nobuhiro ^a   Nishizawa, Sadahiko ^a   Ishizu, Koichi ^a   Okazawa, Hidehiko ^a   Hattori, Naoya ^a   Shibasaki, Hiroshi ^a   Konishi, Junji ^a   Onishi, Yoshihiro ^c  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF FUKUI   (Japan)

^c Amagasaki Front Building   (Japan)

Author keywords

Benzodiazepine receptor; Epilepsy; Iodine 123 iomazenil; Single photon emission tomography

Indexed keywords

BENZODIAZEPINE RECEPTOR; FLUORODEOXYGLUCOSE F 18; IODINE 123; IOMAZENIL; RADIOPHARMACEUTICAL AGENT;

ADULT; ARTICLE; BRAIN BLOOD FLOW; BRAIN PERFUSION; BRAIN TOMOGRAPHY; CLINICAL ARTICLE; ELECTROENCEPHALOGRAPHY; EPILEPTIC FOCUS; FEMALE; HUMAN; INTRACTABLE EPILEPSY; INTRAVENOUS DRUG ADMINISTRATION; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PHOTON EMISSION TOMOGRAPHY; POSITRON EMISSION TOMOGRAPHY; PREOPERATIVE EVALUATION;

ADULT; BRAIN; DEOXYGLUCOSE; ELECTROENCEPHALOGRAPHY; EPILEPSY, FRONTAL LOBE; EPILEPSY, TEMPORAL LOBE; FEASIBILITY STUDIES; FEMALE; FLUMAZENIL; FLUORINE RADIOISOTOPES; FLUORODEOXYGLUCOSE F18; HUMANS; IODINE RADIOISOTOPES; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PREOPERATIVE CARE; TOMOGRAPHY, EMISSION-COMPUTED; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 8044231948     PISSN: 03406997     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01728305     Document Type: Article

References (35)

1. Spencer SS. The relative contributions of MRI, SPECT, and PET imaging in epilepsy. Epilepsia 1994; 35: S72-S89.
2. Jibiki I, Yamaguchi N. Epilepsy and SPECT. Neurosci Biobehav Rev 1994; 18: 281-290.
3. Nagata T, Tanaka F, Yonekura Y, et al. Limited value of interictal brain perfusion SPECT for detection of epileptic foci: high resolution SPECT studies in comparison with FDG-PET. Ann Nucl Med 1995; 9: 59-63.
4. Engel J, Henry TR, Risinger MW, et al. Presurgical evaluation for epilepsy: relative contribution of chronic depth electrode recording versus FDG-PET and scalp-sphenoidal ictal EEG. Neurology 1990; 40: 1670-1677.
5. Sackellares JC, Siegel GJ, Abou-Khalil BW, et al. Differences between lateral and mesial temporal metabolism interictally in epilepsy of mesial temporal origin. Nurology 1990; 40: 1420-1426.
6. 18F-FDG positron emission tomography. Neurology 1993; 43: 79-86.
7. Rowe CC, Berkovic SF, Austin MC, et al. Patterns of postietal cerebral blood flow in temporal lobe epilepsy: qualitative and quantitative analysis. Neurology 1991; 41: 1096-1103.
8. Duncan R, Patterson J, Roberts R, et al. Ictal/postictal SPECT in the presurgical localization of complex partial seizures. J Neurol Neurosurg Psychiatry 1993; 56: 141-148.
9. Newton MR, Berkovic SF, Austin MC, et al. Postictal switch in blood flow distribution and temporal lobe seizures. J Neurol Neurosurg Psychiatry 1992; 55: 819-894.
10. Newton MR, Berkovic SF, Austin MC, et al. Ictal postictal and interictal single-photon emission tomography in the later-alization of temporal lobe epilepsy. J Nucl Med 1994; 21: 1067-1071.
11. Savic I, Persson A, Roland O, et al. In-vivo demonstration of reduced benzodiazepine-receptor binding in human epileptic foci. Lancet 1988; 863-866.
12. Henry TR, Frey KA, Sackellares JC, et al. In vivo cerebral metabolism and central benzodiazepine-receptor binding in temporal lobe epilepsy. Neurology 1993; 43: 1998-2006.
13. 18F]FDG as PET markers of epileptic foci. J Neurol Neurosurg Psychiatry 1993; 56: 615-621.
14. 18FDG-PET and ictal EEC findings in patients with medically intractable complex partial seizures. Acta Neurochir Suppl (Wien) 1990; 50: 95-99.
15. Bartenstein P, Ludolph A, Schober O, et al. Benzodiazepine receptors and cerebral blood flow in partial epilepsy. Eur J Nucl Med 1991; 18: 111-118.
16. Schubiger PA, Hasler PH, Beer-Wohlfahrt H, et al. Evaluation of a multicentre study with iomazenil - a benzodiazepine ligand. Nucl Med Commun 1991; 12: 569-582.
17. 99mTc-HMPAO-SPECT. CT and MR. Adv Exp Med Biol 1991; 287: 405-412.
18. Johnson EW, de Lanerolle NC, Kim JH, et al. "Central" and "peripheral" benzodiazepine receptors: opposite changes in human epileptogenic tissue. Neurology 1992; 42: 811-815.
19. Cordes M, Henkes H, Ferstl F, et al. Evaluation of focal epilepsy: a SPECT scanning comparison of 123-I-Iomazenil versus HM-PAO. Am J Neuroradiol 1992; 13: 249-253.
20. 123I-iomazenil SPECT. Epilepsy Res 1993; 15: 61-66.
21. Onishi Y, Yonekura Y, Muaki T, et al. Simple quantification of benzodiazepine receptor binding and ligand transport using iodine-123-iomazenil and two SPECT scans. J Nucl Med 1995; 36: 1201-1210.
22. Onishi Y, Yonekura Y, Nishizawa S, et al. Noninvasive method of iodine-123-iomazenil SPECT. J Nucl Med 1996: 37: 374-378.
23. Jibiki I, Yamaguchi N, Matsuda H, et al. Paradoxical enhancement of hypoperfusion single photon emission CT images in epileptic focus with bemegride activation. Eur Neurol 1992; 32: 146-150.
24. Beer HF, Blauenslein PA, Hasler PH, et al. In vitro and in vivo evaluation of iodine-123-Ro 16-0154: a new imaging agent for SPECT investigations of benzodiazepine receptors. J Nucl Med 1990; 31: 1007-1014.
25. 123I]Ro 16-0154. Psychiatry Res: Neuroimaging 1992; 45: 67-77.
26. Hoell K, Deisenhammer E, Dauth J, et al. Imaging benzodiazepine receptors in the human brain by single photon emission computed tomography (SPECT). Nucl Med Biol 1989; 16: 759-763.
27. 99mTc-labeled tracers: an overview. J Cereb Blood Flow Metab 1988; 8: S1-S3.
28. 99mTc-ECD SPECT and continuons arterial sampling. Ann Nucl Med 1996; 10: 177-183.
29. Tsuchida T, Nishizawa S, Yonekura Y, et al. SPECT images of technetium-99m-ethyl cysteinate dimer in cerebrovascular disease: comparison with other cerebral perfusion tracers and PET. J Nucl Med 1994; 35: 27-31.
30. Yonekura Y, Nishizawa S, Mukai T, et al. Functional mapping of flow and back-diffusion rate of N-isopropyl-p-iodoamphetamine in human brain. J Nucl Med 1993; 34: 839-844.
31. Spencer SS, Williamson PD, Bridgers SL, et al. Reliability and accuracy of localization by scalp ictal EEG. Neurology 1985; 35: 1567-1575.
32. Sammaritano M, de Lotbiniere A, Andermann F, et al. False lateralization by surface EEG of seizure onset in patients with temporal lobe epilepsy and gross focal cerebral lesions. Ann Neurol 1987; 21: 361-369.
33. Engel J, Brown WJ, Kuhl DE, et al. Pathological findings underlying focal temporal lobe hypometabolism in partial epilepsy. Ann Neurol 1982; 12: 518-528.
34. Morrell F, Secondary epileptogenesis in man. Arch Neurol 1985; 42: 318-335.
35. Spencer SS, Williamson PD, Spencer DD, et al. Human hippocampal seizure spread studied by depth and subdural recording: the hippocampal commissure. Epilepsia 1987; 28: 479-489.