Induction of apoptosis in multi-drug resistant (MDR) human glioblastoma cells by SN-38, a metabolite of the camptothecin derivative CPT-11

Cancer Chemotherapy and Pharmacology

Volumn 39, Issue 5, 1997, Pages 417-423

  Nakatsu, Shouji ^a   Kondo, Seiji ^b   Kondo, Yasuko ^b   Yin, Dali ^c   Peterson, John W ^b   Kaakaji, Rami ^b   Morimura, Tatsuo ^c   Kikuchi, Haruhiko ^a   Takeuchi, Juji ^c   Barnett, Gene H ^b  

^a KYOTO UNIVERSITY   (Japan)

^b LERNER RESEARCH INSTITUTE   (United States)

^c UTANO NATIONAL HOSPITAL   (Japan)

Author keywords

Apoptosis; Camptothecin; Chemotherapy; Glioma; Multidrug resistance; SN 38

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; 7 ETHYL 10 HYDROXYCAMPTOTHECIN; CAMPTOTHECIN; CAMPTOTHECIN DERIVATIVE;

APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; FLOW CYTOMETRY; GLIOBLASTOMA; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CAMPTOTHECIN; CELL CYCLE; CELL LINE; CELL SURVIVAL; DNA, NEOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE; FLOW CYTOMETRY; GLIOBLASTOMA; HUMANS; KINETICS; TUMOR CELLS, CULTURED;

EID: 8044231335     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050592     Document Type: Article

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