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Volumn 92, Issue 2, 1997, Pages 197-203

Phagocytic degradation of chylomicron remnants by fibroblasts from subjects with homozygous familial hypercholesterolaemia

Author keywords

Atherosclerosis; Chylomicron remnants; Hypercholesterolaemia; Phagocytosis

Indexed keywords

ALPHA 2 MACROGLOBULIN; CELL SURFACE PROTEIN; CHYLOMICRON; CYTOCHALASIN D; LACTOFERRIN; LIPOPROTEIN; LIPOPROTEIN RECEPTOR; LOW DENSITY LIPOPROTEIN RECEPTOR; POLYINOSINIC ACID;

EID: 8044229406     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs0920197     Document Type: Article
Times cited : (5)

References (24)
  • 1
    • 0020472786 scopus 로고
    • The LDL receptor defect in familial hypercholesterolemia: Implication for pathogenesis and therapy
    • Goldstein JL, Brown MS. The LDL receptor defect in familial hypercholesterolemia: implication for pathogenesis and therapy. Med Clin North Am 1982; 66: 335-62.
    • (1982) Med Clin North Am , vol.66 , pp. 335-362
    • Goldstein, J.L.1    Brown, M.S.2
  • 2
    • 0020653918 scopus 로고
    • Formation and metabolism of chylomicrons
    • Redgrave TG. Formation and metabolism of chylomicrons. Int Rev Physiol 1983; 28: 103-30.
    • (1983) Int Rev Physiol , vol.28 , pp. 103-130
    • Redgrave, T.G.1
  • 3
    • 0025095799 scopus 로고
    • Chylomicron remnant clearance from the plasma is normal in familial hypercholesterolemic homozygotes with defined receptor defects
    • Rubinsztein DC, Cohen JC, Berger M, van der Westhuyzen DR, Coetzee GA, Gevers W. Chylomicron remnant clearance from the plasma is normal in familial hypercholesterolemic homozygotes with defined receptor defects. J Clin Invest 1990; 86: 1306-12.
    • (1990) J Clin Invest , vol.86 , pp. 1306-1312
    • Rubinsztein, D.C.1    Cohen, J.C.2    Berger, M.3    Van Der Westhuyzen, D.R.4    Coetzee, G.A.5    Gevers, W.6
  • 4
    • 0029587248 scopus 로고
    • Atherosclerosis as a postprandial disease
    • Mamo JCL. Atherosclerosis as a postprandial disease. Endocrinol Metab 1995; 2: 229-44.
    • (1995) Endocrinol Metab , vol.2 , pp. 229-244
    • Mamo, J.C.L.1
  • 5
    • 0028096947 scopus 로고
    • Postprandial apolipoprotein B100 and B48 metabolism in familial combined hyperlipidaemia before and after reduction of fasting plasma triglycerides
    • Castro-Cabezas M, Erkelens DW, Kock LAW, de Bruin TWA. Postprandial apolipoprotein B100 and B48 metabolism in familial combined hyperlipidaemia before and after reduction of fasting plasma triglycerides. Eur J Clin Invest 1994; 24: 669-78.
    • (1994) Eur J Clin Invest , vol.24 , pp. 669-678
    • Castro-Cabezas, M.1    Erkelens, D.W.2    Kock, L.A.W.3    De Bruin, T.W.A.4
  • 6
    • 0348038758 scopus 로고
    • Hepatic uptake of chylomicron remnants in WHHL rabbits: A mechanism genetically distinct from the low density lipoprotein receptor
    • Kita T, Goldstein JL, Brown MS, Watanabe Y, Hornick CA, Havel RJ. Hepatic uptake of chylomicron remnants in WHHL rabbits: a mechanism genetically distinct from the low density lipoprotein receptor. Proc Natl Acad Sci USA 1982; 79: 3623-7.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 3623-3627
    • Kita, T.1    Goldstein, J.L.2    Brown, M.S.3    Watanabe, Y.4    Hornick, C.A.5    Havel, R.J.6
  • 7
    • 0025860543 scopus 로고
    • Chylomicron-remnant clearance in homozygote and heterozygote Watanabe-heritable-hyperlipidaemic rabbits is defective. Lack of evidence for an independent chylomicron-remnant receptor
    • Bowler A, Redgrave TG, Mamo JCL. Chylomicron-remnant clearance in homozygote and heterozygote Watanabe-heritable-hyperlipidaemic rabbits is defective. Lack of evidence for an independent chylomicron-remnant receptor. Biochem J 1991; 276: 381-6.
    • (1991) Biochem J , vol.276 , pp. 381-386
    • Bowler, A.1    Redgrave, T.G.2    Mamo, J.C.L.3
  • 8
    • 0028933044 scopus 로고
    • Chylomicron metabolism in normal, cholesterol-fed and Watanabe Heritable Hyperlipidemic rabbits. Saturation of the sequestration step of the remnant clearance pathway
    • Hussain MM, Innerarity TL, Brecht BJ, Mahley RW. Chylomicron metabolism in normal, cholesterol-fed and Watanabe Heritable Hyperlipidemic rabbits. Saturation of the sequestration step of the remnant clearance pathway. J Biol Chem 1995; 270: 8578-87.
    • (1995) J Biol Chem , vol.270 , pp. 8578-8587
    • Hussain, M.M.1    Innerarity, T.L.2    Brecht, B.J.3    Mahley, R.W.4
  • 9
    • 0028268018 scopus 로고
    • The two receptor model of lipoprotein clearance: Test of the hypothesis in knockout mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins
    • Ishibashi S, Herz J, Maeda N, Goldstein JL, Brown MS. The two receptor model of lipoprotein clearance: test of the hypothesis in knockout mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins. Proc Natl Acad Sci USA 1994; 91: 4431-5.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4431-4435
    • Ishibashi, S.1    Herz, J.2    Maeda, N.3    Goldstein, J.L.4    Brown, M.S.5
  • 10
    • 0025991653 scopus 로고
    • Use of an anti-low density lipoprotein receptor antibody to quantify the role of the LDL receptor in the removal of chylomicron remnants in the mouse in vivo
    • Choi SY, Fong LG, Kirven MJ, Cooper AD. Use of an anti-low density lipoprotein receptor antibody to quantify the role of the LDL receptor in the removal of chylomicron remnants in the mouse in vivo. J Clin Invest 1991; 88: 1171-81.
    • (1991) J Clin Invest , vol.88 , pp. 1171-1181
    • Choi, S.Y.1    Fong, L.G.2    Kirven, M.J.3    Cooper, A.D.4
  • 11
    • 0024449363 scopus 로고
    • The LDL receptor related protein, LRP, is an apolipoprotein e binding protein
    • Beisiegel U, Weber W, Ihrke G, Herz J, Stanley KK. The LDL receptor related protein, LRP, is an apolipoprotein E binding protein. Nature (London) 1989; 14: 162-4.
    • (1989) Nature (London) , vol.14 , pp. 162-164
    • Beisiegel, U.1    Weber, W.2    Ihrke, G.3    Herz, J.4    Stanley, K.K.5
  • 12
    • 0025940314 scopus 로고
    • Lipoprotein lipase enhances the binding of chylomicrons to low density lipoprotein receptor-related protein
    • Beisiegel U, Weber W, Bengtsson-Olivercrona G. Lipoprotein lipase enhances the binding of chylomicrons to low density lipoprotein receptor-related protein. Proc Natl Acad Sci USA 1991; 88: 8342-6.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 8342-8346
    • Beisiegel, U.1    Weber, W.2    Bengtsson-Olivercrona, G.3
  • 13
    • 0028284556 scopus 로고
    • Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist
    • Washington DC
    • Willnow TE, Sheng Z, Ishibashi S, Herz J. Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist. Science (Washington DC) 1994; 264: 1471-4.
    • (1994) Science , vol.264 , pp. 1471-1474
    • Willnow, T.E.1    Sheng, Z.2    Ishibashi, S.3    Herz, J.4
  • 15
    • 0025847767 scopus 로고
    • The human asialoglycoprotein receptor is a possible binding site for low-density lipoproteins and chylomicron remnants
    • Windler E, Greeve J, Levkau B, Kolb-Bachofen V, Daerr W, Greten H. The human asialoglycoprotein receptor is a possible binding site for low-density lipoproteins and chylomicron remnants. Biochem J 1991; 276: 79-87.
    • (1991) Biochem J , vol.276 , pp. 79-87
    • Windler, E.1    Greeve, J.2    Levkau, B.3    Kolb-Bachofen, V.4    Daerr, W.5    Greten, H.6
  • 16
    • 0028326257 scopus 로고
    • Identification of a lipolysis-stimulated receptor that is distinct from the LDL receptor and the LDL receptor-related protein
    • Yen FT, Mann CJ, Guermani LM, et al. Identification of a lipolysis-stimulated receptor that is distinct from the LDL receptor and the LDL receptor-related protein. Biochemistry 1994; 33: 1172-80.
    • (1994) Biochemistry , vol.33 , pp. 1172-1180
    • Yen, F.T.1    Mann, C.J.2    Guermani, L.M.3
  • 17
    • 0029774579 scopus 로고    scopus 로고
    • Degradation of chylomicron remnants by macrophages occurs via phagocytosis
    • Mamo JCL, Elsegood CL, Gennat HC, Yu K. Degradation of chylomicron remnants by macrophages occurs via phagocytosis. Biochemistry 1996; 35: 10210-14.
    • (1996) Biochemistry , vol.35 , pp. 10210-10214
    • Mamo, J.C.L.1    Elsegood, C.L.2    Gennat, H.C.3    Yu, K.4
  • 18
    • 0016850021 scopus 로고
    • Separation of lipoproteins by density gradient ultracentrifugation
    • Redgrave TG, Roberts DCK, West CE. Separation of lipoproteins by density gradient ultracentrifugation. Anal Biochem 1975; 65: 42-9.
    • (1975) Anal Biochem , vol.65 , pp. 42-49
    • Redgrave, T.G.1    Roberts, D.C.K.2    West, C.E.3
  • 19
    • 0028068361 scopus 로고
    • Chylomicrons or their remnants penetrate rabbit thoracic aorta as efficiently as smaller macromolecules including low density lipoprotein, high density lipoprotein and albumin
    • Mamo JCL, Wheeler JR. Chylomicrons or their remnants penetrate rabbit thoracic aorta as efficiently as smaller macromolecules including low density lipoprotein, high density lipoprotein and albumin. Coron Artery Dis 1994; 5: 695-705.
    • (1994) Coron Artery Dis , vol.5 , pp. 695-705
    • Mamo, J.C.L.1    Wheeler, J.R.2
  • 20
    • 0023695667 scopus 로고
    • Mutations of the low density lipoprotein receptor in Japanese kindreds with familial hypercholesterolemia
    • Funahashi T, Miyake Y, Yamamoto A, Matsuzawa YM, Kishino B-I. Mutations of the low density lipoprotein receptor in Japanese kindreds with familial hypercholesterolemia. Hum Genet 1988; 79: 103-8.
    • (1988) Hum Genet , vol.79 , pp. 103-108
    • Funahashi, T.1    Miyake, Y.2    Yamamoto, A.3    Matsuzawa, Y.M.4    Kishino, B.-I.5
  • 21
    • 0025281029 scopus 로고
    • Expression of the acetyl low density lipoprotein receptor by rabbit fibroblasts and smooth muscle cells
    • Pitas RE. Expression of the acetyl low density lipoprotein receptor by rabbit fibroblasts and smooth muscle cells. J Biol Chem 1990; 265: 12722-7.
    • (1990) J Biol Chem , vol.265 , pp. 12722-12727
    • Pitas, R.E.1
  • 23
    • 0028173897 scopus 로고
    • Structures and functions of multiligand lipoprotein receptors: Macrophage scavenger receptors and LDL receptor-related protein (LRP)
    • Krieger M, Herz, J. Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP). Ann Rev Biochem 1994; 63: 601-37.
    • (1994) Ann Rev Biochem , vol.63 , pp. 601-637
    • Krieger, M.1    Herz, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.