Relationship of polymorphisms in the renin-angiotensin system and in E-selectin of patients with early severe coronary heart disease

Journal of Molecular Medicine

Volumn 75, Issue 1, 1997, Pages 57-61

  Wenzel, K ^a   Blackburn, A ^a   Ernst, M ^a   Affeldt, M ^a   Hanke, R ^a   Baumann, G ^a   Felix, S B ^a   Kleber, F X ^a   Rohde, K ^b   Glaser C ^c   Speer, A ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

angiotensin converting enzyme; angiotensinogen; coronary heart disease; E selectin; genotype

Indexed keywords

ANGIOTENSINOGEN; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

ADULT; ANGIOTENSINS; CORONARY DISEASE; E-SELECTIN; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; RENIN;

EID: 8044223407     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001090050087     Document Type: Article

References (16)

1. Cambien F (1992) Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 359:641-644
2. Mattu RK, Needham EWA, Galton DJ, Frangos E, Clark AJL, Caulfield M (1995) A DNA variant at the angiotensin-converting enzyme gene locus associates with coronary artery disease in the Caerphilly Heart Study. Circulation 91:270-274
3. Schunkert H, Hense HW, Holmer SR, Stender M, Perz S, Keil, U, Lorell BH, Riegger GAJ (1994) Association between a deletion polymorphism of the angiotensin-converting-enzyme gene and the left ventricular hypertrophy. N Engl J Med 330:1634-1638
4. Miettinen HE, Korpela K, Hämäläinen L, Kontula K (1994) Polymorphisms of the apolipoprotein and angiotensin converting enzyme genes in young North Karelian patients with coronary heart disease. Hum Genet 94:189-1892
5. Lindpaintner K, Pfeffer MA, Kreutz R, Stampfer MJ, Grodstein F, LaMotte F, Buring J, Hennekens CH (1995) A prospective evaluation of an angiotensin- converting-enzyme gene polymorphism and the risk of ischemic heart disease. N Engl J Med 332:706-711
6. Celermajer DS, Sorensen KE, Barley J, Jeffrey S, Carter N, Deanfield J (1994) Angiotensin-converting enzyme genotype is not associated with endothelial dysfunction in subjects without other coronary risk factors. Atherosclerosis 111:121-126
7. Jeunemaitre X, Soubrier F, Kotelevtsev YV, Lifton RP, Williams CS, Charru A, Hunt SC, Hopkins PN, Williams RR, Lalouel JM, Corvol P (1992) Molecular basis of human hypertension: role of angiotensinogen. Cell 71:169-180
8. Soubrier F, Cambien F (1993) Renin-angiotensin system genes as candidate genes in cardiovascular diseases. Teratog Carcinog Mutagen 3:250-158
9. Hata A, Namikawa C, Sasaki M, Sato K, Nakamura T, Tamura K, Lalouel JM (1994) Angiotensinogen as a risk factor for essential hypertension in Japan. J Clin Invest 93:1285-1287
10. Ishigami T, Umemura S, Iwamoto T, Tamura K, Hibi K, Yamaguchi S, Nyuui N, Kimura K, Miyazaki N, Ishii M (1995) Molecular variant of angiotensinogen gene is associated with coronary atherosclerosis. Circulation 91:951-954
11. Caulfield M, Lavender P, Farrall M, Munroe P, Lawson M, Turner P, Clark AJ (1994) Linkage of the angiotensinogen gene to essential hypertension. N Engl Med 330:1629-1633
12. Tiret L, Ricard S, Poirier O, Arveiler D, Cambou JP, Luc G, Evans A, Nicaud V, Cambien F (1995) Genetic variation at the angiotensinogen locus in relation to high blood pressure and myocardial infarction: the ECTIM study. J Hypertension 13: 311-317
13. Wenzel K, Felix S, Kleber FX, Brachold R, Menke T, Schattke S, Schulte KL, Gläser C, Rohde K, Baumann G, Speer A (1994) E-selectin polymorphism and atherosclerosis: an association study. Hum Mol Genet 3:1935-1937
14. Davies KE, Speer A, Herrmann F, Spiegler AWJ, McGlade S, Hofker MH, Briand P, Hanke R, Schwartz M, Steinbicker V, Szibor R, Körner H, Sommer D, Pearson PL, Coutelle C (1985) Human X chromosome markers and Duchenne muscular dystrophy. Nucleic Acid Res 13:3419-2346
15. Rigat B, Hubert C, Corvol P, Soubrier F (1992) PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1). Nucleic Acid Res 20:1433
16. Wenzel K, Hanke R, Speer A (1994) A polymorphism in the human E-selectin gene detected by PCR-SSCP. Hum Genet 94:319-330