Enhancement of N-nitrosodiethylamine-initiated hepatocarcinogenesis caused by a colchicine-induced cell cycle disturbance in partially hepatectomized rats

Cancer Research

Volumn 56, Issue 15, 1996, Pages 3474-3479

  Ohashi, Kazuo ^a   Tsutsumi, Masahiro ^a   Tsujiuchi, Toshifumi ^a   Kobitsu, Kunihiko ^a   Okajima, Eijiro ^a   Nakajima, Yoshiyuki ^a   Nakano, Hiroshige ^a   Takahashi, Midori ^b   Mori, Yukio ^b   Konishi, Yoichi ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

^b GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; BROXURIDINE; CARBON TETRACHLORIDE; COLCHICINE; DIETHYLNITROSAMINE; GAMMA GLUTAMYLTRANSFERASE; N (2 FLUORENYL)ACETAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE; CONTROLLED STUDY; LABELING INDEX; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER NECROSIS; LIVER REGENERATION; MALE; MITOSIS INDEX; MUTAGENICITY; NONHUMAN; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; RAT;

ANIMALS; CARCINOGENS; CELL CYCLE; CELL DIVISION; COCARCINOGENESIS; COLCHICINE; DIETHYLNITROSAMINE; GAMMA-GLUTAMYLTRANSFERASE; HEPATECTOMY; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MITOSIS; MUTAGENICITY TESTS; MUTAGENS; NECROSIS; ORGAN SIZE; RATS; RATS, INBRED F344;

EID: 8044219690     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Motokura, T., and Arnold, A. Cyclins and oncogenesis. Biochim. Biophys. Acta, 25: 63-78, 1993.
2. Murray, A. W. Creative blocks: cell-cycle checkpoints and feedback controls. Nature (Lond.), 359: 599-604, 1992.
3. El-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parrson, R., Trent, J. M., Lin, M., Mercer, W. E., Kinzler, K. W., and Vogelstein, B. Waf1, a potent mediator of p53 tumor suppression. Cell, 75: 817-825, 1993.
4. Hinds, P. W., Dowdy, S. F., Eaton, E. N., Arnold, A., and Weinberg, R. A. Function of a human cyclin gene as an oncogene Proc. Natl. Acad. Sci. USA, 91: 709-713, 1994.
5. Kamb, A., Gruis, N. A., Weaver-Feldhaus, J., Liu, Q., Harshman, S., Tavtigian, S. V., Stockert, E., Day, R. S., III, Johnson, B. E., and Skolnick, M. H. A cell cycle regulator potentially involved in genesis of many tumor types. Science (Washington DC), 264: 436-440, 1994.
6. Cohen, S. M., and Ellwein, L. B. Cell proliferation in carcinogenesis. Science (Washington DC), 249: 1007-1011, 1990.
7. Hartung, E. F. Colchicine and its analogs in gout. Arthritis Rheum., 4: 18-32, 1961.
8. Kung, A. L., Sherwood, S. W., and Schimke, R. T. Cell line-specific differences in the control of cell cycle progression in the absence of mitosis. Proc. Natl. Acad. Sci. USA, 87: 9553-9557, 1990.
9. Higgins, G. M., and Anderson, R. M. Experimental pathology of the liver: restoration of the liver of the white rat following partial surgical removal. Arch. Pathol., 12: 186-202, 1931.
10. Cayama, E., Tsuda, H., Sarma, D. S. R., and Farber, E. Initiation of chemical carcinogenesis requires cell proliferation. Nature (Lond.), 275: 60-62, 1978.
11. Squire, R. A., and Levitt, M. H. Report of a workshop on classification of specific hepatocellular lesions in rats. Cancer Res., 35: 3214-3223, 1975.
12. Rutenberg, A. M., Kim, H., Fishbein, J. W., Hankers, J. S., Wasserkrug, H. L., and Seligman, A. M. Histochemical and ultrastructural demonstration of γ-glutamyltranspeptidase activity. J. Histochem. Cytochem., 17: 517-526, 1969.
13. Tatematsu, M., Nagamine, Y., and Farber, E. Redifferentiation as a basis for remodeling of carcinogen-induced hepatocyte nodules to normal appearing liver. Cancer Res., 43: 5049-5058, 1983.
14. Campbell, H. A., Pitot, H. C. E., Potter, V. R., and Laishes, B. A. Application of quantitative stereology to the evaluation of enzyme-altered foci in rat liver. Cancer Res., 42, 465-472, 1982.
15. Hsu, S. M., Raine, L., and Farger, H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques, a comparison between ABC and unlabelled antibody PAP procedures. J. Histochem Cytochem., 29: 577-580, 1981.
16. Mori, Y., Yamazaki, H., Toyoshi, K., Ucida, K., Tsutsumi, M., and Konishi, Y. Inhibitory effect of organic solvents on the mutagenicity of N-nitrosodialkylamines in Salmonella. Mutat. Res., 142: 153-158, 1985.
17. Mori, Y., Imura, K., and Konishi, Y. A new cytochrome p450 inducer for Ames test. Environ. Mat. Res. Commun., 16: 195-204, 1994.
18. Mori, Y., Yamazaki, H., Toyoshi, K., Makino, T., Obara, T., Yokose, Y., and Konishi, Y. Mutagenic activation of carcinogenic N-nitrosopropylamines by rat liver: evidence for a cytochrome P-450 dependent reaction. Carcinogenesis (Lond.), 6: 415-420, 1985.
19. Yahagi, T., Nagao, M., Seino, T., Matsushima, T., Sugimura, T., and Okada, M. Mutagenicities of N-nitrosamines on Salmonella. Mutat. Res., 48: 121-130, 1977.
20. Mori, Y., Niwa, T., Hori, T., and Toyoshi, K. Mutagenicity of 3′-methyl-N,N-dimethyl-4-aminoazobenzene metabolites and related compounds Carcinogenesis (Lond.), 1: 121-127, 1981.
21. Maron, D., Katzenellenborgen, J., and Ames, B. N. Compatibility of organic solvents with the Salmonella/microsome test Mutat. Res., 88: 343-350, 1981.
22. Nagasue, N., Kobayashi, M., Iwaki, A., Yukaya, H., Kanashima, R., and Inoguchi, K. Effect of 5-fluorouracil on liver regeneration and metabolism after partial hepatectomy in rats. Cancer (Phila.), 41: 435-443, 1978.
23. Tamura, J., Tanaka, J., Fujita, K., Yoshida, M., Kasamatsu, T., Arii, S., and Tobe, T. Effect of anticancer agents on cell cycle of regenerating hepatocytes in rats. J. Surg. Res., 53: 218-226, 1992.
24. Bucher, N. L. R. Regeneration of mammalian liver Int. Rev. Cytol., 15: 245-300, 1963.
25. Garcia, R. L., Coltrera, M. D., and Gown, A. M. Analysis of proliferative grade using anti-PCNA/cyclin monoclonal antibodies in fixed, embedded tissue. Am. J. Pathol., 134: 733-739, 1989.
26. Lovec, H., Sewing, A., Lucibello, F. C., Muler, R., and Moroy, T. Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: link between cell cycle control and malignant transformation. Oncogene, 9: 323-326, 1994.
27. Chander, N., Lombardi, B., and Locker, J. c-myc gene amplification during hepatocarcinogenesis by a choline-devoid diet. Proc Natl. Acad. Sci. USA, 86: 2703-2707, 1989.
28. Solt, D. B., Medline, A., and Farber, E. Rapid emergence of carcinogen-induced hyperplastic lesions in a new model for the sequential analysis of liver carcinogenesis. Am. J. Pathol., 88: 595-618, 1977.
29. Rizzoni, M., and Palitti, F. Regulatory mechanism of cell division. I. Colchicine-induced endoreduplication Exp. Cell Res., 77: 450-458, 1973.
30. Herreros, B., Guerro, A., and Romo, E. Colcemid-induced polyploidy. Lancet, 2: 500-501, 1966.
31. Kung, A. L., Sherwood, S. W., and Schimke, R. T. Cell line-specific differences in the control of cell cycle progression in the absence of mitosis. Proc. Natl. Acad Sci. USA, 87: 9553-9557, 1990.
32. Huang, Y., Chang, C. C., and Trosko, J. E. Aphidicolin-induced endoreduplication in Chinese hamster cells. Cancer Res., 43: 1361-1364, 1983.
33. DeWald, M. G., Sharma, R. C., Kung, A. L., Wong, H. E., Sherwood, S. W., and Schimke, R. T. Heterogeneity in the mitotic checkpoint control of BALB/3T3 cells and a correlation with gene amplification propensity. Cancer Res., 54: 5064-5070, 1994.
34. Borisy, G. G., and Taylor, E. W. The mechanism of action of colchicine. Binding of colchicine-3H to cellular protein J. Cell Biol. 34: 533-548, 1967.
35. Diegelmann, R. F., and Peterkofsky, B. Inhibition of collagen secretion from bone and cultured fibroblasts by microtubular disruptive drugs. Proc. Natl. Acad. Sci. USA, 69: 892-896, 1972.
36. 2 inhibitor, of both cirrhosis and enzyme-altered nodules caused by a choline-deficient, L-amino acid-defined diet in rats Carcinogenesis, 17: 467-475, 1996.