Intracranial injection of adeno-associated viral vectors

Journal of Visualized Experiments

Volumn , Issue 45, 2010, Pages

  Lowery, Rebecca L ^a   Majewska, Ania K ^a  

^a UNIVERSITY OF ROCHESTER   (United States)

Author keywords

Adeno associated virus; Cortex; Imaging; Injections; Issue 45; Labeling; Mouse; Neuroscience; Virus

Indexed keywords

EID: 80355143939     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/2140     Document Type: Article

References (4)

1. Kaplitt, M.G., Leone, P., Samulski, R.J., Xiao, X., Pfaff, D.W., O'Malley, K.L., During, M.J. Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nat Genet 8:148-154 (1994).
2. Harding, T.C., Dickinson, P.J., Roberts, B.N., Yendluri, S., Gonzalez-Edick, M., Lecouteur, R.A., Jooss, K.U. Enhanced gene transfer efficiency in the murine striatum and an orthotopic glioblastoma tumor model, using AAV-7-and AAV-8-pseudotyped vectors. Hum Gene Ther 17:807-820 (2006).
3. Lo, W.D., Qu, G., Sferra, T.J., Clark, R., Chen, R., Johnson, P.R. Adeno-associated virus-mediated gene transfer to the brain: duration and modulation of expression. Hum Gene Ther 10:201-213 (1999).
4. Lowery, R.L., Zhang, Y., Kelly, E.A., Lamantia, C.E., Harvey, B.K., Majewska, A.K. Rapid, long-term labeling of cells in the developing and adult rodent visual cortex using double-stranded adeno-associated viral vectors. Dev Neurobiol 69:674-688 (2009).