A reverse genetic approach to test functional redundancy during embryogenesis

Journal of Visualized Experiments

Volumn , Issue 42, 2010, Pages

  Rikin, Amir ^a   Rosenfeld, Gabriel E ^a   McCartin, Kellie ^a   Evans, Todd ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Cardiogenesis; Developmental Biology; Issue 42; Morpholinos; Protocol; Zebrafish

Indexed keywords

EID: 80355140471     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/2020     Document Type: Article

References (6)

1. Heicklen-Klein, A., McReynolds, L. J. & Evans, T. Using the zebrafish model to study GATA transcription factors. Semin Cell Dev Biol 16, 95-106, (2005).
2. Bill, B. R., Petzold, A. M., Clark, K. J., Schimmenti, L. A. & Ekker, S. C. A primer for morpholino use in zebrafish. Zebrafish 6, 69-77, (2009).
3. Holtzinger, A. & Evans, T. Gata5 and Gata6 are functionally redundant in zebrafish for specification of cardiomyocytes. Dev Biol 312, 613-622 (2007).
4. Peterkin, T., Gibson, A. & Patient, R. Redundancy and evolution of GATA factor requirements in development of the myocardium. Dev Biol 311, 623-635 (2007).
5. Holtzinger, A. & Evans, T. Gata4 regulates the formation of multiple organs. Development 132, 4005-4014, (2005).
6. Sorrentino, R. P., Gajewski, K. M. & Schulz, R. A. GATA factors in Drosophila heart and blood cell development. Semin Cell Dev Biol 16, 107-116, (2005).