Long-term culture of human breast cancer specimens and their analysis using Optical Projection Tomography

Journal of Visualized Experiments

Volumn , Issue 53, 2011, Pages

  Leeper, Alexander D ^a   Farrell, Joanne ^b   Dixon Michael, J ^a   Wedden, Sarah E ^b   Harrison, David J ^a   Katz, Elad ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b MRC Technology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 80355132685     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/3085     Document Type: Article

References (8)

1. Lopez-Garcia, M.A., Geyer, F.C., Lacroix-Triki, M., Marchio, C., & Reis-Filho, J.S. Breast cancer precursors revisited: molecular features and progression pathways. Histopathology. 57, 171-192 (2010).
2. Sabeh, F., Shimizu-Hirota, R., & Weiss, S.J. Protease-dependent versus-independent cancer cell invasion programs: three-dimensional amoeboid movement revisited. J Cell Biol. 185, 11-19 (2009).
3. Dabrosin, C. Increased extracellular local levels of estradiol in normal breast in vivo during the luteal phase of the menstrual cycle. J Endocrinol. 187, 103-108 (2005).
4. Alanentalo, T., et al. Tomographic molecular imaging and 3D quantification within adult mouse organs. Nat Methods. 4, 31-33 (2007).
5. Sharpe, J., et al. Optical projection tomography as a tool for 3D microscopy and gene expression studies. Science. 296, 541-545 (2002).
6. Hidalgo-Carcedo, C. et al. Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6. Nat Cell Biol. 13, 49-58, doi:ncb2133 [pii] 10.1038/ncb2133 (2011).
7. Katz, E., et al. A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of Syk. Br J Cancer. 103, 401-410, doi:6605763 [pii] 10.1038/sj.bjc.6605763 (2010).
8. Timpson, P. et al. Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53. Cancer Res. 71, 747-757, doi:0008-5472.CAN-10-2267 [pii] 10.1158/0008-5472.CAN-10-2267 (2011).