How can benfluorex-related heart valve disease be identified by echocardiography?

Archives of Cardiovascular Diseases

Volumn 104, Issue 10, 2011, Pages 489-492

  Tribouilloy, Christophe ^a   Rusinaru, Dan ^a   Andréjak, Michel ^a,b  

^a AMIENS UNIVERSITY HOSPITAL   (France)

^b UNIVERSITÉ DE PICARDIE JULES VERNE   (France)

Author keywords

Benfluorex; Drug induced valvular disease; Valvular regurgitation

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; BENFLUOREX; CABERGOLINE; DEXFENFLURAMINE; ERGOTAMINE; FENFLURAMINE; GYNERGENE; METHYSERGIDE MALEATE; PERGOLIDE MESILATE; UNCLASSIFIED DRUG;

AORTA VALVE REGURGITATION; DIFFERENTIAL DIAGNOSIS; DRUG EXPOSURE; DRUG INDICATION; DRUG SURVEILLANCE PROGRAM; ECHOCARDIOGRAPHY; FRANCE; HUMAN; HYPERTRIGLYCERIDEMIA; MITRAL VALVE REGURGITATION; OBESITY; PULMONARY HYPERTENSION; REVIEW; TRICUSPID VALVE REGURGITATION; VALVULAR HEART DISEASE;

EID: 80255137460     PISSN: 18752136     EISSN: 18752128     Source Type: Journal    
DOI: 10.1016/j.acvd.2011.07.001     Document Type: Article

References (17)

1. S. Bhattacharyya, A.H. Schapira, and D.P. Mikhailidis Drug-induced fibrotic valvular heart disease Lancet 374 2009 577 585
2. H.M. Connolly, J.L. Crary, and M.D. McGoon Valvular heart disease associated with fenfluramine-phentermine N Engl J Med 337 1997 581 588 (Pubitemid 27360757)
3. L. Abenhaim, Y. Moride, and F. Brenot Appetite-suppressant drugs and the risk of primary pulmonary hypertension. International Primary Pulmonary Hypertension study group N Engl J Med 335 1996 609 616 (Pubitemid 26277950)
4. G. Van Camp, A. Flamez, and B. Cosyns Heart valvular disease in patients with Parkinson's disease treated with high-dose pergolide Neurology 61 2003 859 861 (Pubitemid 37174494)
5. S. Droogmans, B. Cosyns, and H. D'Haenen Possible association between 3,4-methylenedioxymethamphetamine abuse and valvular heart disease Am J Cardiol 100 2007 1442 1445 (Pubitemid 47576024)
6. K. Boutet, I. Frachon, and Y. Jobic Fenfluramine-like cardiovascular side-effects of benfluorex Eur Respir J 33 2009 684 688
7. I. Frachon, Y. Etienne, and Y. Jobic Benfluorex and unexplained valvular heart disease: a case-control study PLoS One 5 2010 e10128
8. J.P. Gueffet, N. Piriou, and J.N. Trochu Valvular heart disease associated with benfluorex Arch Cardiovasc Dis 103 2010 342 343
9. C. Hill Number of deaths attributable to benfluorex Presse Med 40 2011 462 469
10. F. Le Ven, C. Tribouilloy, and G. Habib Valvular heart disease associated with benfluorex therapy: results from the French multicentre registry Eur J Echocardiogr 12 2011 265 271
11. P. Noize, M. Sauer, and P. Bruneval Valvular heart disease in a patient taking benfluorex Fundam Clin Pharmacol 20 2006 577 578 (Pubitemid 44762174)
12. J. Rafel Ribera, R. Casanas Munoz, and N. Anguera Ferrando Valvular heart disease associated with benfluorex Rev Esp Cardiol 56 2003 215 216 (Pubitemid 36305071)
13. C. Tribouilloy, D. Rusinaru, and P. Henon Restrictive organic mitral regurgitation associated with benfluorex therapy Eur J Echocardiogr 11 2010 614 621
14. A. Weill, M. Paita, and P. Tuppin Benfluorex and valvular heart disease: a cohort study of a million people with diabetes mellitus Pharmacoepidemiol Drug Saf 19 2010 1256 1262
15. S. Droogmans, D. Kerkhove, and B. Cosyns Role of echocardiography in toxic heart valvulopathy Eur J Echocardiogr 10 2009 467 476
16. C.F. Dahl, and M.R. Allen Regression and progression of valvulopathy associated with fenfluramine and phentermine Ann Intern Med 136 2002 489 (Pubitemid 34233182)
17. C.F. Dahl, M.R. Allen, and P.M. Urie Valvular regurgitation and surgery associated with fenfluramine use: an analysis of 5743 individuals BMC Med 6 2008 34