Identification of small-molecule inhibitors of Trypansoma cruzi replication

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 23, 2011, Pages 7197-7200

  Germain, Andrew R ^a   Carmody, Leigh C ^a   Dockendorff, Chris ^a   Galan Rodriguez, Cristina ^b   Rodriguez, Ana ^b   Johnston, Stephen ^a   Bittker, Joshua A ^a   MacPherson, Lawrence ^a   Dandapani, Sivaraman ^a   Palmer, Michelle ^a   Schreiber, Stuart L ^a   Munoz, Benito ^a  

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Chagas disease; Molecular Libraries Probe Production Center Network (MLPCN); Trypansoma cruzi

Indexed keywords

ANTIPARASITIC AGENT; NIPECOTIC ACID; NIPECOTIC AMIDE; PYRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL VIABILITY; DRUG INHIBITION; DRUG STRUCTURE; HOST CELL; NONHUMAN; TRYPANOSOMA CRUZI;

INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

EID: 80255136324     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.09.057     Document Type: Article

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