Multisite evaluation of a point-of-care instrument for CD4+ T-cell enumeration using venous and finger-prick blood: The PIMA CD4

Journal of Acquired Immune Deficiency Syndromes

Volumn 58, Issue 4, 2011, Pages

  Diaw, Papa Alassane ^a   Daneau, Géraldine ^b   Coly, Abdoul Aziz ^a   Ndiaye, Birahim Pierre ^a   Wade, Djibril ^a   Camara, Makhtar ^a   Mboup, Souleymane ^a   Kestens, Luc ^b   Dieye, Tandakha Ndiaye ^a  

^a UNIVERSITÉ CHEIKH ANTA DIOP   (Senegal)

^b INSTITUTE OF TROPICAL MEDICINE   (Belgium)

Author keywords

CD4 + T cell count; FACSCount; finger prick; HIV; PIMA; point of care

Indexed keywords

ADULT; ANALYTICAL EQUIPMENT; ARTICLE; BLOOD ANALYSIS; CAPILLARY BLOOD; CD4 LYMPHOCYTE COUNT; CONTROLLED STUDY; FEMALE; HOSPITAL INFORMATION SYSTEM; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; MAJOR CLINICAL STUDY; MALE; PIMA CD4 ANALYZER; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; VENOUS BLOOD;

ADULT; CD4 LYMPHOCYTE COUNT; FEMALE; HIV INFECTIONS; HUMANS; MALE; MASS SCREENING; MIDDLE AGED; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 80255136149     PISSN: 15254135     EISSN: 10779450     Source Type: Journal    
DOI: 10.1097/QAI.0b013e318235b378     Document Type: Article

References (20)

1. UNAIDS. Report on the Global AIDS Epidemic. Geneva, Switzerland: UNAIDS; 2008.
2. Lynen L, Thai S, De MP, et al. The added value of a CD4 count to identify patients eligible for highly active antiretroviral therapy among HIV-positive adults in Cambodia. J Acquir Immune Defic Syndr. 2006; 42:322-324. (Pubitemid 44050010)
3. World Health Organization. Antiretroviral Therapy for HIV Infection in Adults and Adolescents: Recommendations for a Public Health Approach. WHO. 2010.
4. Mandy F, Janossy G, Bergeron M, et al. Affordable CD4 T-cell enumeration for resource-limited regions: a status report for 2008. Cytometry B Clin Cytom. 2008;74(suppl 1):S27-S39. (Pubitemid 351569270)
5. Mtapuri-Zinyowera S, Chideme M, Mangwanya D, et al. Evaluation of the PIMA point-of-care CD4 analyzer in VCT clinics in Zimbabwe. J Acquir Immune Defic Syndr. 2010;55:1-7.
6. Jani IV, Sitoe NE, Chongo PL, et al. Accurate CD4 T-cell enumeration and antiretroviral drug toxicity monitoring in primary healthcare clinics using point-of-care testing. AIDS. 2011;25:807-812.
7. Glencross DK, Coetzee L, Lawrie D, et al. Encouraging point-of-care PIMA CD4 testing performance in a laboratory setting: Johannesburg, South Africa. Presented at: 17th Conference on Retroviruses and Opportunistic Infections; San Francisco, CA; 2010.
8. Glencross DK, Coetzee L, Lawrie D, et al. Performance evaluation of PIMA CD4 point-of-care (POC) analyzer, Johannesburg, South Africa. Presented at: XVIII International AIDS Conference; Vienna, Austria; 2010.
9. Scott LE, Galpin JS, Glencross DK. Multiple method comparison: statistical model using percentage similarity. Cytometry B Clin Cytom. 2003;54:46-53. (Pubitemid 38295418)
10. Lin LI. A concordance correlation coefficient to evaluate reproducibility. Biometrics. 1989;45:255-268.
11. Passing H, Bablok. A new biometrical procedure for testing the equality of measurements from two different analytical methods. Application of linear regression procedures for method comparison studies in clinical chemistry, Part I. J Clin Chem Clin Biochem. 1983;21:709-720. (Pubitemid 14208512)
12. Bland JM, Altman DG. Measuring agreement in method comparison studies. Stat Methods Med Res. 1999;8:135-160. (Pubitemid 29425900)
13. Cohen J. A coefficient of agreement for nominal scales. Educ Psychol Meas. 1960;20:37-46.
14. Sitoe N, Luecke E, Tembe N, et al. Absolute and percent CD4+ T-cell enumeration by flow cytometry using capillary blood. J Immunol Methods. 2011;372:1-6.
15. Cecelia AJ, Balakrishnan P, Mohanakrishnan, et al. Effective evaluation of novel low-cost CD4 monitoring assays. J Immunol Methods. 2006; 316:158-162. (Pubitemid 44604387)
16. Dieye TN, Vereecken C, Diallo AA, et al. Absolute CD4 T-cell counting in resource-poor settings: direct volumetric measurements versus bead-based clinical flow cytometry instruments. J Acquir Immune Defic Syndr. 2005; 39:32-37. (Pubitemid 40617016)
17. Lynen L, Teav S, Vereecken C, et al. Validation of primary CD4 gating as an affordable strategy for absolute CD4 counting in Cambodia. J Acquir Immune Defic Syndr. 2006;43:179-185. (Pubitemid 44454811)
18. Pattanapanyasat K, Phuang-Ngern Y, Lerdwana S, et al. Evaluation of a single-platform microcapillary flow cytometer for enumeration of absolute CD4+ T-lymphocyte counts in HIV-1 infected Thai patients. Cytometry B Clin Cytom. 2007;72:387-396. (Pubitemid 350194356)
19. Spacek LA, Shihab HM, Lutwama F, et al. Evaluation of a low-cost method, the Guava EasyCD4 assay, to enumerate CD4-positive lymphocyte counts in HIV-infected patients in the United States and Uganda. J Acquir Immune Defic Syndr. 2006;41:607-610.
20. Janik I, Sitoe N, Alfai E, et al. Point-of-care CD4 improves patient retention and time-to-initiation of ART in Mozambique. Presented at: XVIII International AIDS Conference; Vienna, Austria; 2010.