Choroidal blood flow response to isometric exercise in glaucoma patients and patients with ocular hypertension

Investigative Ophthalmology and Visual Science

Volumn 52, Issue 10, 2011, Pages 7068-7073

  Portmann, Natalie ^a   Gugleta, Konstantin ^a   Kochkorov, Asan ^a   Polunina, Anna ^a   Flammer, Josef ^a   Orgul, Selim ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTERIAL PRESSURE; ARTICLE; CHOROIDAL BLOOD FLOW; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; EYE BLOOD FLOW; FEMALE; HAND GRIP; HUMAN; INTRAOCULAR HYPERTENSION; INTRAOCULAR PRESSURE; ISOMETRIC EXERCISE; LASER DOPPLER FLOWMETRY; MAJOR CLINICAL STUDY; MALE; OPEN ANGLE GLAUCOMA; PERFUSION PRESSURE; PRIORITY JOURNAL; RETINAL NERVE FIBER LAYER THICKNESS; TONOMETRY; VISUAL FIELD; VISUAL SYSTEM PARAMETERS; BLOOD FLOW; BLOOD FLOW VELOCITY; BLOOD PRESSURE; CHOROID; CLINICAL TRIAL; EXERCISE; MIDDLE AGED; NERVE FIBER; OCULOPLETHYSMOGRAPHY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RETINA GANGLION CELL; VASCULARIZATION;

BLOOD FLOW VELOCITY; BLOOD PRESSURE; CHOROID; EXERCISE; FEMALE; GLAUCOMA, OPEN-ANGLE; HUMANS; INTRAOCULAR PRESSURE; LASER-DOPPLER FLOWMETRY; MALE; MIDDLE AGED; NERVE FIBERS; OCULAR HYPERTENSION; REGIONAL BLOOD FLOW; RETINAL GANGLION CELLS; TONOMETRY, OCULAR; VISUAL FIELDS;

EID: 80155192563     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-7758     Document Type: Article

References (41)

1. Flammer J, Orgul S, Costa VP, et al. The impact of ocular blood flow in glaucoma. Prog Retin Eye Res. 2002;21:359-393.
2. Caprioli J, Coleman AL. Blood pressure, perfusion pressure, and glaucoma. Am J Ophthalmol. 2010;149:704-712.
3. Riva CE, Titze P, Hero M, Petrig BL. Effect of acute decreases of perfusion pressure on choroidal blood flow in humans. Invest Ophthalmol Vis Sci. 1997;38:1752-1760.
4. Riva CE, Titze P, Hero M, et al. Choroidal blood flow during isometric exercises. Invest Ophthalmol Vis Sci. 1997;38:2338-2343.
5. Findl O, Strenn K, Wolzt M, et al. Effects of changes in intraocular pressure on human ocular haemodynamics. Curr Eye Res. 1997; 16:1024-1029.
6. Polska E, Simader C, Weigert G, et al. Regulation of choroidal blood flow during combined changes in intraocular pressure and arterial blood pressure. Invest Ophthalmol Vis Sci. 2007;48:3768-3774.
7. Kiss B, Fuchsjager G, Polak K, et al. Age dependence of perimacular white blood cell flux during isometric exercise. Curr Eye Res. 2000;21:757-762.
8. Kiss B, Dallinger S, Polak K, et al. Ocular hemodynamics during isometric exercise. Microvasc Res. 2001;61:1-13.
9. Movaffaghy A, Chamot SR, Dosso A, et al. Effect of isometric exercise on choroidal blood flow in type I diabetic patients. Klin Monatsbl Augeheilkd. 2002;219:299-301.
10. Polska E, Luksch A, Schering J, et al. Propranolol and atropine do not alter choroidal blood flow regulation during isometric exercise in healthy humans. Microvasc Res. 2003;65:39-44.
11. Wimpissinger B, Resch H, Berisha F, et al. Effects of isometric exercise on subfoveal choroidal blood flow in smokers and nonsmokers. Invest Ophthalmol Vis Sci. 2003;44:4859-4863.
12. Luksch A, Polska E, Imhof A, et al. Role of NO in choroidal blood flow regulation during isometric exercise in healthy humans. Invest Ophthalmol Vis Sci. 2003;44:734-739.
13. Fuchsjager-Mayrl G, Luksch A, Malec M, et al. Role of endothelin-1 in choroidal blood flow regulation during isometric exercise in healthy humans. Invest Ophthalmol Vis Sci. 2003;44:728-733.
14. Tittl M, Maar N, Polska E, et al. Choroidal hemodynamic changes during isometric exercise in patients with inactive central serous chorioretinopathy. Invest Ophthalmol Vis Sci. 2005;46:4717-4721.
15. Pournaras CJ, Logean E, Riva CE, et al. Regulation of subfoveal choroidal blood flow in age-related macular degeneration. Invest Ophthalmol Vis Sci. 2006;47:1581-1586.
16. Lovasik JV, Kergoat H, Riva CE, et al. Choroidal blood flow during exercise-induced changes in the ocular perfusion pressure. Invest Ophthalmol Vis Sci. 2003;44:2126-2132.
17. Hayashi N, Ikemura T, Someya N. Effects of dynamic exercise and its intensity on ocular blood flow in humans. Eur J Appl Physiol. Published online March 5, 2011.
18. Lovasik JV, Kergoat H. Consequences of an increase in the ocular perfusion pressure on the pulsatile ocular blood flow. Optom Vis Sci. 2004;81:692-698.
19. Schmidt KG, Mittag TW, Pavlovic S, Hessemer V. Influence of physical exercise and nifedipine on ocular pulse amplitude. Graefes Arch Clin Exp Ophthalmol. 1996;234:527-532.
20. Kozobolis VP, Detorakis ET, Konstas AG, et al. Retrobulbar blood flow and ophthalmic perfusion in maximum dynamic exercise. Clin Exp Ophthalmol. 2008;36:123-129.
21. Khurana RK, Setty A. The value of the isometric hand-grip test: studies in various autonomic disorders. Clin Auton Res. 1996;6: 211-218.
22. Schmetterer L, Dallinger S, Findl O, et al. Noninvasive investigations of the normal ocular circulation in humans. Invest Ophthalmol Vis Sci. 1998;39:1210-1220.
23. Gugleta K, Orgul S, Hasler PW, et al. Choroidal vascular reaction to hand-grip stress in subjects with vasospasm and its relevance in glaucoma. Invest Ophthalmol Vis Sci. 2003;44:1573-1580.
24. Metelitsina TI, Grunwald JE, DuPont JC, Ying GS. Effect of isometric exercise on choroidal blood flow in patients with age-related macular degeneration. Br J Ophthalmol. 2010;94:1629-1631.
25. Kashiwagi K, Hosaka O, Kashiwagi F, et al. Systemic circulatory parameters comparison between patients with normal tension glaucoma and normal subjects using ambulatory monitoring. Jpn J Ophthalmol. 2001;45:388-396.
26. Plange N, Kaup M, Daneljan L, et al. 24-h blood pressure monitoring in normal tension glaucoma: night-time blood pressure variability. J Hum Hypertens. 2006;20:137-142.
27. Choi J, Kim KH, Jeong J, et al. Circadian fluctuation of mean ocular perfusion pressure is a consistent risk factor for normal-tension glaucoma. Invest Ophthalmol Vis Sci. 2007;48:104-111.
28. Joe SG, Choi J, Sung KR, et al. Twenty-four hour blood pressure pattern in patients with normal tension glaucoma in the habitual position. Kor J Ophthalmol. 2009;23:32-39.
29. Kochkorov A, Gugleta K, Katamay R, et al. Short-term variability of systemic blood pressure and submacular choroidal blood flow in eyes of patients with primary open-angle glaucoma. Graefes Arch Clin Exp Ophthalmol. 2010;248:833-837.
30. Geiser M, Diermann U, Riva CE. Compact laser Doppler choroidal flowmeter. J Biomed Opt. 1999;4:459-464.
31. Guelen I, Westerhof BE, Van Der Sar GL, et al. Finometer, finger pressure measurements with the possibility to reconstruct brachial pressure. Blood Press Monit. 2003;8:27-30.
32. Findl O, Strenn K, Wolzt M, et al. Effects of changes in intraocular pressure on human ocular haemodynamics. Curr Eye Res. 1997; 16:1024-1029.
33. Gugleta K, Orgul S, Flammer I, et al. Reliability of confocal choroidal laser Doppler flowmetry. Invest Ophthalmol Vis Sci. 2002; 43:723-728.
34. Duijm HF, van den Berg TJ, Greve EL. Choroidal haemodynamics in glaucoma. Br J Ophthalmol. 1997;81:735-742.
35. Grunwald JE, Piltz J, Hariprasad SM, DuPont J. Optic nerve and choroidal circulation in glaucoma. Invest Ophthalmol Vis Sci. 1998;39:2329-2336.
36. Sugiyama T, Schwartz B, Takamoto T, Azuma I. Evaluation of the circulation in the retina, peripapillary choroid and optic disk in normal-tension glaucoma. Ophthalmic Res. 2000;32:79-86.
37. Kerr J, Nelson P, O'Brien C. A comparison of ocular blood flow in untreated primary open-angle glaucoma and ocular hypertension. Am J Ophthalmol. 1998;126:42-51.
38. Fuchsjager-Mayrl G, Wally B, Georgopoulos M, et al. Ocular blood flow and systemic blood pressure in patients with primary openangle glaucoma and ocular hypertension. Invest Ophthalmol Vis Sci. 2004;45:834-839.
39. Movaffaghy A, Pharmakakis NM, Chamot SR, et al. Effect of squatting on sub-foveal blood flow defect in pseudophakic eyes operated by cerclage (in German). Klin Monatsbl Augenheilkd. 2001; 218:323-326.
40. Qureshi IA. The effects of mild, moderate, and severe exercise on intraocular pressure in glaucoma patients. Jpn J Physiol. 1995;45: 561-569.
41. Leung CK, Chan WM, Yung WH, et al. Comparison of macular and peripapillary measurements for the detection of glaucoma: an optical coherence tomography study. Ophthalmology. 2005;112: 391-400.