Contrast-enhanced ultrasound of hepatocellular carcinoma: Correlation of washout time and angiogenesis

Clinical Hemorheology and Microcirculation

Volumn 48, Issue 4, 2011, Pages 265-273

  Xia, Y ^a   Jiang, Y X ^a   Dai, Q ^a   Xiao, Y ^a   Lv, K ^a   Wang, L ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

Author keywords

Angiogenesis; contrast enhanced ultrasound (CEUS); hepatocellular carcinoma (HCC); washout time

Indexed keywords

ADULT; AGED; ANGIOGENESIS; ARTICLE; CLINICAL ARTICLE; CONTRAST ENHANCED ULTRASOUND; CONTRAST ENHANCEMENT; FEMALE; HUMAN; HUMAN TISSUE; LIVER CELL CARCINOMA; MALE; MICROVASCULATURE; PARAMETER; TIME; TUMOR DIFFERENTIATION; ULTRASOUND; WASHOUT TIME;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; CONTRAST MEDIA; FEMALE; HUMANS; IMAGE ENHANCEMENT; LIVER NEOPLASMS; MALE; MICROBUBBLES; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; PHOSPHOLIPIDS; SULFUR HEXAFLUORIDE; ULTRASONOGRAPHY;

EID: 80155191296     PISSN: 13860291     EISSN: 18758622     Source Type: Journal    
DOI: 10.3233/CH-2011-1420     Document Type: Article

References (32)

1. M. J. Blomley, P. S. Sidhu, D. O. Cosgrove, T. Albrecht, C. J. Harvey, R. A. Heckemann, J. Butler-Barnes, R. J. Eckersley and R. Basilico, Do different types of liver lesions differ in their uptake of the microbubble contrast agent SH U 508A in the late liver phase? Early experience, Radiology 220 (2001), 661-667. (Pubitemid 32799972)
2. M. Brannigan, P. N. Burns and S. R. Wilson, Blood flow patterns in focal liver lesions at microbubble-enhanced US, RadioGraphics 24 (2004), 921-935. (Pubitemid 38943326)
3. D. O. Cosgrove, A revolution in liver ultrasound, Eur J Gastroenterol Hepatol 19 (2007), 1-2. (Pubitemid 46066861)
4. M. D'Onofrio, E. Martone, N. Faccioli, G. Zamboni, R. Malagò and R. P. Mucelli, Focal liver lesions: Sinusoidal phase of CEUS, Abdom Imaging 31 (2006), 529-536. (Pubitemid 46360855)
5. A. Eberhard, S. Kahlert,V. Goede, B. Hemmerlein, K. H. Plate and H. G. Augustin, Heterogeneity of angiogenesis and blood vessel maturation in human tumors: Implications for antiangiogenic tumor therapies, Cancer Res 60 (2000), 1388-1393. (Pubitemid 30152012)
6. H. A. Edmondson and P. E. Steiner, Primary carcinoma of the liver: A study of 100 cases among 48,900 necropsies, Cancer 7 (1954), 462-503.
7. O. N. El-Assal, A. Yamanoi, Y. Soda, M. Yamaguchi, M. Igarashi, A. Yamamoto, T. Nabika and N. Nagasue, Clinical significance of microvessel density and vascular endothelial growth factor expression in hepatocellular carcinoma and surrounding liver: Possible involvement of vascular endothelial growth factor in the angiogenesis of cirrhotic liver, Hepatology 27 (1998), 1554-1562. (Pubitemid 28264678)
8. Z. H. Fan, M. H. Chen, Y. Dai, Y. B. Wang, K. Yan, W. Wu, W. Yang and S. S. Yin, Evaluation of primary malignancies of the liver using contrast-enhanced sonography: Correlation with pathology, Am J Roentgenol 186 (2006), 512-519.
9. C. Greis, Ultrasound contrast agents as markers of vascularity and microcirculation, Clin Hemorheol Microcirc 43 (2009), 1-9.
10. H. J. Jang, T. K. Kim, P. N. Burns and S. R. Wilson, Enhancement patterns of hepatocellular carcinoma at contrast-enhanced US: Comparison with histologic differentiation, Radiology 244 (2007), 898-906. (Pubitemid 47292103)
11. E. M. Jung, D. A. Clevert, A. G. Schreyer, S. Schmitt, J. Rennert, R. Kubale, S. Feuerbach and F. Jung, Evaluation of quantitative contrast harmonic imaging to assess malignancy of liver tumors: A prospective controlled two-center study, World J Gastroenterol 13 (2007), 6356-6364.
12. E. M. Jung, C. J. Ross, J. Rennert, M. N. Scherer, S. Farkas, P. von Breitenbuch, A. A. Schnitzbauer, P. Piso, P. Lamby, C. Menzel, A. G. Schreyer, S. Feuerbach, H. J. Schlitt and M. Loss, Characterization of microvascularization of liver tumor lesions with high resolution linear ultrasound and contrast enhanced ultrasound (CEUS) during surgery: First results, Clin Hemorheol Microcirc 46 (2010), 9-99.
13. E. M. Jung, A. G. Schreyer, D. Schacherer, C. Menzel, S. Farkas, M. Loss, S. Feuerbach, N. Zorger and C. Fellner, New real-time image fusion technique for characterization of tumor vascularisation and tumor perfusion of liver tumors with contrast-enhanced ultrasound, spiral CT or MRI: First results, Clin Hemorheol Microcirc 43 (2009), 57-69.
14. C. K. Kim, J. H. Lim, C. K. Park, D. Choi, H. K. Lim and W. J. Lee, Neoangiogenesis and sinusoidal capillarization in hepatocellular carcinoma: Correlation between dynamic CT and density of tumor microvessels, Radiology 237 (2005), 529-534. (Pubitemid 41507890)
15. T. K. Kim, H. J. Jang and S. R. Wilson, Imaging diagnosis of hepatocellular carcinoma with differentiation from other pathology, Clin Liver Dis 9 (2005), 253-279.
16. M. Kin, T. Torimura, T. Ueno, S. Inuzuka and K. Tanikawa, Sinusoid capillarization in small hepatocellular carcinoma, Pathol Int 44 (1994), 771-778. (Pubitemid 24320465)
17. E. Leen, The role of contrast-enhanced ultrasound in the characterisation of focal liver lesions, Eur Radiol 11 (suppl 3) (2001), E27-E34. (Pubitemid 34041347)
18. G. J. Liu, H. X. Xu, M. D. Lu, X. Y. Xie, Z. F. Xu, Y. L. Zheng and J. Y. Liang, Correlation between enhancement pattern of hepatocellular carcinoma on real-time contrast-enhanced ultrasound and tumour cellular differentiation on histopathology, Br J Radiol 80 (2007), 321-330.
19. J. A. Marrero, Screening tests for hepatocellular carcinoma, Clin Liver Dis 9 (2005), 235-251.
20. S. Nakamura, H. Muro, S. Suzuki, T. Sakaguchi, H. Konno, S. Baba and A. S. Syed, Immunohistochemical studies on endothelial cell type in hepatocellular carcinoma, Hepatol 26 (1997), 407-415. (Pubitemid 27328319)
21. C. Nicolau, V. Catalá, R. Vilana, R. Gilabert, L. Bianchi, M. Solé, M. Pagés and C. Brú, Evaluation of hepatocellular carcinoma using SonoVue, a second generation ultrasound contrast agent: correlation with cellular differentiation, Eur Radiol 14 (2004), 1092-1099. (Pubitemid 38787254)
22. R. T. Poon, I. O. Ng, C. Lau, W. C. Yu, Z. F. Yang, S. T. Fan and J. Wong, Tumour microvessel density as a predictor of recurrence after resection of hepatocellular carcinoma: A prospective study, J Clin Oncol 20 (2002), 1775-1785. (Pubitemid 34273266)
23. C. J. Ross, J. Rennert, D. Schacherer, C. Girlich, P. Hoffstetter, P. Heiss, W. Jung, S. Feuerbach, N. Zorger and E. M. Jung, Image fusion with volume navigation of contrast enhanced ultrasound (CEUS) with computed tomography (CT) or magnetic resonance imaging (MRI) for post-interventional follow-up after transcatheter arterial chemoembolization (TACE) of hepatocellular carcinomas (HCC): Preliminary results, Clin Hemorheol Microcirc 46 (2010), 101.
24. D. Schacherer, C. Girlich, R. Wiest, R. Büttner, J. Schölmerich, S. Feuerbach, N. Zorger, O. W. Hamer and E. M. Jung, Semiquantitative characterization of hepatocellular carcinoma (HCC)-perfusion with contrast-enhanced ultrasound and perfusion analysis, Clin Hemorheol Microcirc 44 (2010), 97-105.
25. M. Schneider, Sono Vue, a new ultrasound contrastagent, Eur Radiol 9 (Suppl 3) (1999), S347-S348.
26. H. C. Sun, Z. Y. Tang, X. M. Li, Y. N. Zhou, B. R. Sun and Z. C. Ma, Microvessel density of hepatocellular carcinoma: Its relationship with prognosis, J Cancer Res Clin Oncol 125 (1999), 419-426.
27. N. Tanigawa, C. Lu, T. Mitsui and S. Miura, Quantitation of sinusoid-like vessels in hepatocellular carcinoma: Its clinical and prognostic significance, Hepatology 26 (1997), 1216-1223. (Pubitemid 27509306)
28. P. B. Vermeulen, G. Gasparini, S. B. Fox, M. Toi, L. Martin, P. McCulloch, F. Pezzella, G. Viale, N. Weidner, A. L. Harris and L. Y. Dirix, Quantification of angiogenesis in solid human tumours: An international consensus on the methodology and criteria of evaluation, Eur J Cancer 32A (1996), 2474-2484.
29. B. Wang, Z. Q. Gao and X. Yan, Correlative study of angiogenesis and dynamic contrast-enhanced magnetic resonance imaging features of hepatocellular carcinoma, Acta Radiol 46 (2005), 353-358. (Pubitemid 41657464)
30. N. Weidner, J. P. Semple, W. R. Welch and J. Folkman, Tumor angiogenesis and metastasis: Correlation in invasive breast carcinoma, N Engl J Med 324 (1991), 1-8.
31. A. Yamamoto, D. K. Dhar, O. N. El-Assal, M. Igarashi, H. Tabara and N. Nagasue, Thymidine phosphorylase (plateletderived endothelial cell growth factor), microvessel density and clinical outcome in hepatocellular carcinoma, J Hepatol 29 (1998), 290-299. (Pubitemid 28352815)
32. N. Zorger, E. M. Jung, A. G. Schreyer, P. Heiss, R. Mueller-Wille, R. Wiest, S. Feuerbach and J. Rennert, Ultrasoundarterioportography (US-AP): A new technical approach to perform detection of liver lesions, Clin Hemorheol Microcirc 46 (2010), 117-126.