Distension of the uterus induces HspB1 expression in rat uterine smooth muscle

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 301, Issue 5, 2011, Pages

  White, B G ^a   MacPhee, D J ^a  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

Heat shock protein B1; Mechanical stress; Myometrium; Stretch; Uterus

Indexed keywords

HEAT SHOCK PROTEIN 27; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FEMALE; GESTATIONAL AGE; MECHANICAL STRESS; MYOMETRIUM; NONHUMAN; OVARIECTOMY; PREGNANCY OUTCOME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; THIRD TRIMESTER PREGNANCY; UTERUS CONTRACTILITY; UTERUS HORN;

ANIMALS; FEMALE; GESTATIONAL AGE; HSP27 HEAT-SHOCK PROTEINS; MECHANOTRANSDUCTION, CELLULAR; MYOMETRIUM; OVARIECTOMY; PHOSPHORYLATION; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SERINE; STRESS, MECHANICAL; UP-REGULATION;

EID: 80155165207     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00272.2011     Document Type: Article

References (53)

1. Benndorf R, Hayess K, Ryazantsev S, Wieske M, Behlke J, Lutsch G. Phosphorylation and supramolecular organization of murine small heat shock protein HSP25 abolish its actin polymerization inhibiting activity. J Biol Chem 269: 20780-20784, 1994.
2. Bitar KN. HSP27 phosphorylation and interaction with actin and myosin in smooth muscle contraction. Am J Physiol Gastrointest Liver Physiol 282: G894-G903, 2002.
3. Bornfeldt KE. Stressing rac, ras, and downstream heat shock protein 70. Circ Res 86: 1101-1103, 2000.
4. Bradford MM. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
5. Challis JRG, Lye SJ. Characteristics of parturition. In: Maternal-Fetal Medicine: Principles and Practice, edited by Resnik R, Creasy RK. Philadelphia, PA: Saunders, 2004.
6. Chaudhuri S, Smith PG. Cyclic strain-induced hsp27 phosphorylation modulates actin filaments in airway smooth muscle cells. Am J Respir Cell Mol Biol 39: 270-278, 2008.
7. During RL, Gibson BG, Li W, Bishai EA, Sidhu GS, Landry J, Southwick FS. Anthrax lethal toxin paralyzes actin-based motility by blocking hsp27 phosphorylation. EMBO J 26: 2240-2250, 2007.
8. Gaestel M, Schroder W, Benndorf R, Lippmann C, Buchner K, Hucho F, Erdmann VA, Bielka H. Identification of the phosphorylation sites of the murine small heat shock protein Hsp25. J Biol Chem 266: 14721-14724, 1991.
9. Gaestel M. sHSP-phosphorylation: enzymes, signaling pathways, and functional implications. In: Progress in Molecular and Subcellular Biology, edited by Arrigo AP, Muller WEG. Berlin: Springer-Verlag, 2002.
10. Ibitayo AI, Sladick J, Tuteja S, Louis-Jacques O, Yamada H, Groblewski G, Welsh M, Bitar KN. Hsp27 in signal transduction and association with contractile proteins in smooth muscle cells. Am J Physiol Gastrointest Liver Physiol 277: G445-G454, 1999.
11. Jaffer S, Shynlova O, Lye S. Mammalian target of rapamycin is activated in association with myometrial proliferation during pregnancy. Endocrinology 150: 4672-4680, 2009.
12. Jia Y, Wu SL, Isenberg JS, Dai S, Sipes JM, Field L, Zeng B, Bandle RW, Ridnour LA, Wink DA, Ramchandran R, Karger BL, Roberts DD. Thiolutin inhibits endothelial cell adhesion by perturbing Hsp27 interactions with components of the actin and intermediate filament cytoskeleton. Cell Stress Chaperones 15: 165-181, 2010.
13. Kampinga HH, Hageman J, Vos MJ, Kubota H, Tanguay RM, Bruford EA, Cheetham ME, Chen B, Hightower LE. Guidelines for the nomenclature of the human heat shock proteins. Cell Stress Chaperones 14: 105-111, 2009.
14. Kappe G, Franck E, Verschuure P, Boelens WC, Leunissen JA, de Jong WW. The human genome encodes 10 -crystallin-related small heat shock proteins: HspB1-10. Cell Stress Chaperones 8: 53-61, 2003.
15. Kato K, Hasegawa K, Goto S, Inaguma Y. Dissociation as a result of phosphorylation of an aggregated form of the small stress protein, hsp27. J Biol Chem 269: 11274-11278, 1994.
16. Kato K, Ito H, Inaguma Y. Expression and phosphorylation of mammalian small heat shock proteins. In: Progress in Molecular and Subcellular Biology, edited by Arrigo AP, Muller WEG. Berlin: Springer-Verlag, 2002.
17. Kostenko S, Moens U. Heat shock protein 27 phosphorylation: kinases, phosphatases, functions, and pathology. Cell Mol Life Sci 66: 3289-3307, 2009.
18. Laemmli UK. Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature 227: 680-685, 1970.
19. Lambert H, Charette SJ, Bernier AF, Guimond A, Landry J. HSP27 multimerization mediated by phosphorylation-sensitive intermolecular interactions at the amino terminus. J Biol Chem 274: 9378-9385, 1999.
20. Landry J, Lambert H, Zhou M, Lavoie JN, Hickey E, Weber LA, Anderson CW. Human HSP27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated protein kinases that recognize the same amino acid motif as S6 kinase II. J Biol Chem 267: 794-803, 1992.
21. Larsen JK, Yamboliev IA, Weber LA, Gerthoffer WT. Phosphorylation of the 27-kDa heat shock protein via p38 MAP kinase and MAPKAP kinase in smooth muscle. Am J Physiol Lung Cell Mol Physiol 273: L930-L940, 1997.
22. Laskowska E, Matuszewska E, Kuczynska-Wisnik D. Small heat shock proteins and protein-misfolding diseases. Curr Pharm Biotech 11: 146-157, 2010.
23. Lavoie JN, Gingras-Breton G, Tanguay RM, Landry J. Induction of Chinese hamster Hsp27 gene expression in mouse cells confers resistance to heat shock. Hsp27 stabilization of the microfilament organization. J Biol Chem 268: 3420-3429, 1993.
24. Lavoie JN, Hickey E, Weber LA, Landry J. Modulation of actin microfilament dynamics and fluid phase pinocytosis by phosphorylation of heat shock protein 27. J Biol Chem 268: 24210-24214, 1993.
25. Li Y, Gallant C, Malek S, Morgan KG. Focal adhesion signaling is required for myometrial ERK activation and contractile phenotype switch before labor. J Cell Biochem 100: 129-140, 2007.
26. Li Y, Reznichenko M, Tribe RM, Hess PE, Taggart M, Kim H, DeGnore JP, Gangopadhyay S, Morgan KG. Stretch activates human myometrium via ERK, caldesmon and focal adhesion signaling. PLos One 4: e7489, 2009.
27. Luo SS, Sugimoto K, Fujii S, Takemasa T, Fu SB, Yamashita K. Role of heat shock protein 70 in induction of stress fiber formation in rat arterial endothelial cells in response to stretch stress. Acta Histochem Cytochem 40: 9-17, 2007.
28. MacPhee DJ, Lye SJ. Focal adhesion signaling in the rat myometrium is abruptly terminated with the onset of labor. Endocrinology 141: 274-283, 2000.
29. Miron T, Vancompernolle K, Vanderkerckhove J, Wilchek M, Geiger B. A 25 kDa inhibitor of actin polymerization is a low molecular mass heat shock protein. J Cell Biol 114: 255-261, 1991.
30. Monga M, Sanborn BM. Biology and physiology of the reproductive tract and control of myometrial contraction. In: Maternal-Fetal Medicine: Principles and Practice, edited by Resnik R, Creasy RK. Philadelphia, PA: Saunders, 2004.
31. Murlasits Z, Cutlip RG, Geronilla KB, Rao KM, Wonderlin WF, Alway SE. Resistance training increases heat shock protein levels in skeletal muscle of young and old rats. Exp Gerontol 41: 398-406, 2006.
32. Oesterreich S, Hickey E, Weber LA, Fuqua SAW. Basal regulatory promoter elements of the hsp27 gene in human breast cancer cells. Biochem Biophys Res Commun 222: 155-163, 1996.
33. Oldenhof AD, Shynlova OP, Liu M, Langille BL, Lye SJ. Mitogenactivated protein kinases mediate stretch-induced c-fos mRNA expression in myometrial smooth muscle cells. Am J Physiol Cell Physiol 283: C1530-C1539, 2002.
34. Ou CW, Orsino A, Lye SJ. Expression of connexin-43 and connexin-26 in the rat myometrium during pregnancy and labor is differentially regulated by mechanical and hormonal signals. Endocrinology 138: 5398-5407, 1997.
35. Ou CW, Chen ZQ, Qi S, Lye SJ. Increased expression of the rat myometrial oxytocin receptor messenger ribonucleic acid during labor requires both mechanical and hormonal signals. Biol Reprod 59: 1055-1061, 1998.
36. Quinlan R. Cytoskeletal competence requires protein chaperones. In: Progress in Molecular and Subcellular Biology, edited by Arrigo AP, Muller WEG. Berlin: Springer-Verlag, 2002.
37. Rosenblatt JS, Mayer AD, Giordano AL. Hormonal basis during pregnancy for the onset of maternal behavior in the rat. Psychoneuroendocrinology 13: 29-46, 1988.
38. Shaw L, Ahmed S, Austin C, Taggart MJ. Inhibitors of actin filament polymerization attenuate force but not global intracellular calcium in isolated pressurised resistance arteries. J Vasc Res 40: 1-10, 2003.
39. Shynlova O, Mitchell JA, Tsampalieros A, Langille BL, Lye SJ. Progesterone and gravidity differentially regulate expression of extracellular matrix components in the pregnant rat myometrium. Biol Reprod 70: 986-992, 2004.
40. Shynlova O, Tsui P, Dorogin A, Chow M, Lye SJ. Expression and localization of _-smooth muscle and _-actins in the pregnant rat myometrium. Biol Reprod 73: 773-780, 2005.
41. Shynlova O, Oldenhof A, Dorogin A, Xu Q, Mu J, Nashman N, Lye SJ. Myometrial apoptosis: activation of the caspase cascade in the pregnant rat myometrium at midgestation. Biol Reprod 74: 839-849, 2006.
42. Shynlova O, Tsui P, Dorogin A, Langille BL, Lye SJ. Insulin-like growth factors and their binding proteins define specific phases of myometrial differentiation during pregnancy in the rat. Biol Reprod 76: 571-578, 2007.
43. Shynlova O, Tsui P, Jaffer S, Lye SJ. Integration of endocrine and mechanical signals in the regulation of myometrial functions during pregnancy and labour. Eur J Obstet Gynecol Reprod Biol 144: S2-S10, 2009.
44. Shynlova O, Kwong R, Lye SJ. Mechanical stretch regulates hypertrophic phenotype of the myometrium during pregnancy. Reproduction 139: 247-253, 2010.
45. Somara S, Bitar KN. Phosphorylated HSP27 modulates the association of phosphorylated caldesmon with tropomyosin in colonic smooth muscle. Am J Physiol Gastrointest Liver Physiol 291: G630-G639, 2006.
46. Stokoe D, Engel K, Campbell DG, Cohen P, Gaestel M. Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins. FEBS Lett 313: 307-313, 1992.
47. Tabb T, Thilander G, Grover A, Hertzberg E, Garfield R. An immunochemical and immunocytologic study of the increase in myometrial gap junctions (and connexin 43) in rats and humans during pregnancy. Am J Obstet Gynecol 167: 559-567, 1992.
48. Taggart MJ, Morgan KG. Regulation of the uterine contractile apparatus and cytoskeleton. Semin Cell Dev Biol 18: 296-304, 2007.
49. White BG, Williams SJ, Highmore K, MacPhee DJ. Small heat shock protein 27 (Hsp27) expression is highly induced in rat myometrium during late pregnancy and labour. Reproduction 129: 115-126, 2005.
50. 5-integrin (Itga5) is elevated in the rat myometrium during late pregnancy and labour: implications for development of a mechanical syncytium. Biol Reprod 72: 1114-1124, 2005.
51. 1-integrin subunits is altered in rat myometrium during pregnancy and labour. Reprod Fertil Dev 22: 718-732, 2010.
52. Xu Q, Schett G, Li C, Hu Y, Wick G. Mechanical stress-induced heat shock protein 70 expression in vascular smooth muscle cells is regulated by rac and ras small G proteins but not mitogen-activated protein kinases. Circ Res 86: 1122-1128, 2000.
53. Zhang Y, Huang L, Zhang J, Moskophidis D, Mivechi NF. Targeted disruption of hsf1 leads to lack of thermotolerance and defines tissue specific regulation for stress-inducible Hsp molecular chaperones. J Cell Biochem 86: 376-393, 2002.