Downregulation of hemojuvelin prevents inhibitory effects of bone morphogenetic proteins on iron metabolism in hepatocellular carcinoma

Laboratory Investigation

Volumn 91, Issue 11, 2011, Pages 1615-1623

  Maegdefrau, Ulrike ^a   Arndt, Stephanie ^a   Kivorski, Georgi ^a   Hellerbrand, Claus ^a   Bosserhoff, Anja Katrin ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

bone morphogenetic protein 4 and 6; hemojuvelin; hepatocellular carcinoma; hepcidin; iron metabolism

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 6; HEMOJUVELIN; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HEPCIDIN; MESSENGER RNA; SMAD PROTEIN;

3' UNTRANSLATED REGION; ARTICLE; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IRON METABOLISM; LIVER CELL; LIVER CELL CARCINOMA; METHYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANTIMICROBIAL CATIONIC PEPTIDES; BLOTTING, WESTERN; BONE MORPHOGENETIC PROTEINS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GPI-LINKED PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; IRON; LIVER NEOPLASMS; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFECTION;

EID: 80155151898     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2011.123     Document Type: Article

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