Lack of association between apolipoprotein C3 gene polymorphisms and risk of coronary heart disease in a Han population in East China

Lipids in Health and Disease

Volumn 10, Issue , 2011, Pages

  Yu, Juan ^a,b   Huang, Jingjing ^a   Liang, Yan ^a   Qin, Baodong ^a   He, Su ^b   Xiao, Jing ^b   Wang, Huimin ^b   Zhong, Renqian ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b NANTONG UNIVERSITY   (China)

Author keywords

Apolipoprotein C3; Coronary heart disease; Hypertriglyceridemia; Polymorphism

Indexed keywords

APOLIPOPROTEIN C3; CHOLESTEROL; CYSTEINE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; THREONINE; TRIACYLGLYCEROL; LIPID;

ADULT; AMINO ACID SEQUENCE; ANALYTIC METHOD; ARTICLE; CARDIOVASCULAR RISK; CHINESE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE IDENTIFICATION; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HETEROZYGOTE; HUMAN; ISCHEMIC HEART DISEASE; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; SINGLE NUCLEOTIDE POLYMORPHISM; TRIACYLGLYCEROL BLOOD LEVEL; AGED; BLOOD; CASE CONTROL STUDY; CHINA; CORONARY ARTERY DISEASE; GENETICS; MIDDLE AGED; RISK; RISK FACTOR;

ADULT; AGED; APOLIPOPROTEIN C-III; CASE-CONTROL STUDIES; CHINA; CORONARY ARTERY DISEASE; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; LIPIDS; MALE; MIDDLE AGED; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 80155147894     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-10-200     Document Type: Article

References (26)

1. Apolipoprotein C-III predicts cardiovascular mortality in severe coronary artery disease and is associated with an enhanced plasma thrombin generation. Olivieri O, Martinelli N, Girelli D, Pizzolo F, Friso S, Beltrame F, Lotto V, Annarumma L, Corrocher R, J Thromb Haemost 2010 8 3 463 471 10.1111/j.1538-7836. 2009.03720.x 20002542
2. Increased plasma apolipoprotein C-III concentration independently predicts cardiovascular mortality: the Hoorn Study. Scheffer PG, Teerlink T, Dekker JM, Bos G, Nijpels G, Diamant M, Kostense PJ, Stehouwer CD, Heine RJ, Clin Chem 2008 54 8 1325 1330 10.1373/clinchem.2008.103234 18556334
3. Apolipoprotein CIII overexpressing mice are predisposed to diet-induced hepatic steatosis and hepatic insulin resistance. Lee HY, Birkenfeld AL, Jornayvaz FR, Jurczak MJ, Kanda S, Popov V, Frederick DW, Zhang D, Guigni B, Bharadwaj KG, Hepatology 2011 54 5 1650 1660 10.1002/hep.24571 21793029
4. Apolipoprotein CIII links dyslipidemia with atherosclerosis. Kawakami A, Yoshida M, J Atheroscler Thromb 2009 16 1 6 11 10.5551/jat.E607 19262004
5. Common genetic variation in the promoter of the human apo CIII gene abolishes regulation by insulin and may contribute to hypertriglyceridemia. Li WW, Dammerman MM, Smith JD, Metzger S, Breslow JL, Leff T, J Clin Invest 1995 96 6 2601 2605 10.1172/JCI118324 8675624
6. Role of MAPK in apolipoprotein CIII-induced apoptosis in INS-1E cells. Sol EM, Sundsten T, Bergsten P, Lipids Health Dis 2009 8 3 10.1186/1476-511X-8-3 19196457
7. The Effect of APOC3 Promoter Polymorphisms on the Risk of Hypertriglyceridemia in Chinese Han Population With or Without Type 2 Diabetes Mellitus. Yu J, Wang H, Yang S, Yuan J, Chen L, Chen CL, Huang DF, Wang Y, Ju SQ, Zhu J, Laboratory Medicine 2010 41 1 34 39 10.1309/LMUBYPDIVGQWOY2U
8. VLDL, apolipoproteins B, CIII, and E, and risk of recurrent coronary events in the Cholesterol and Recurrent Events (CARE) trial. Sacks FM, Alaupovic P, Moye LA, Cole TG, Sussex B, Stampfer MJ, Pfeffer MA, Braunwald E, Circulation 2000 102 16 1886 1892 11034934
9. An ABC of apolipoprotein C-III: a clinically useful new cardiovascular risk factor? Chan DC, Chen MM, Ooi EM, Watts GF, Int J Clin Pract 2008 62 5 799 809 10.1111/j.1742-1241.2007.01678.x 18201179 (Pubitemid 351533666)
10. A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection. Pollin TI, Damcott CM, Shen H, Ott SH, Shelton J, Horenstein RB, Post W, McLenithan JC, Bielak LF, Peyser PA, Science 2008 322 5908 1702 1705 10.1126/science.1161524 19074352
11. APOC3 null mutation affects lipoprotein profile APOC3 deficiency: from mice to man. Hofker MH, Eur J Hum Genet 2010 18 1 1 2 10.1038/ejhg.2009.126 19623213
12. ApoC-III gene polymorphisms and risk of coronary artery disease. Olivieri O, Stranieri C, Bassi A, Zaia B, Girelli D, Pizzolo F, Trabetti E, Cheng S, Grow MA, Pignatti PF, J Lipid Res 2002 43 9 1450 1457 10.1194/jlr.M200145-JLR200 12235176
13. Impact of APOA5/A4/C3 genetic polymorphisms on lipid variables and cardiovascular disease risk in French men. Dallongeville J, Cottel D, Montaye M, Codron V, Amouyel P, Helbecque N, Int J Cardiol 2006 106 2 152 156 10.1016/j.ijcard.2004.10.065 16321685 (Pubitemid 41728931)
14. Lack of effect of apolipoprotein C3 polymorphisms on indices of liver steatosis, lipid profile and insulin resistance in obese Southern Europeans. Sentinelli F, Romeo S, Maglio C, Incani M, Burza MA, Scano F, Coccia F, Cossu E, Leonetti F, Baroni MG, Lipids Health Dis 2011 10 1 93 10.1186/1476-511X-10-93 21663607
15. Complexities of plasma apolipoprotein C-III metabolism. Sacks FM, Zheng C, Cohn JS, J Lipid Res 2011 52 6 1067 1070 10.1194/jlr.E015701 21421846
16. Apolipoprotein CIII induces expression of vascular cell adhesion molecule-1 in vascular endothelial cells and increases adhesion of monocytic cells. Kawakami A, Aikawa M, Alcaide P, Luscinskas FW, Libby P, Sacks FM, Circulation 2006 114 7 681 687 10.1161/CIRCULATIONAHA.106.622514 16894036 (Pubitemid 44252310)
17. Apolipoprotein CIII in apolipoprotein B lipoproteins enhances the adhesion of human monocytic cells to endothelial cells. Kawakami A, Aikawa M, Libby P, Alcaide P, Luscinskas FW, Sacks FM, Circulation 2006 113 5 691 700 10.1161/CIRCULATIONAHA.105.591743 16461842
18. Apolipoprotein CIII-induced THP-1 cell adhesion to endothelial cells involves pertussis toxin-sensitive G protein- and protein kinase C alpha-mediated nuclear factor-kappaB activation. Kawakami A, Aikawa M, Nitta N, Yoshida M, Libby P, Sacks FM, Arterioscler Thromb Vasc Biol 2007 27 1 219 225 10.1161/01.ATV.0000249620.68705.0d 17038637 (Pubitemid 46360402)
19. Apolipoprotein CIII links hyperlipidemia with vascular endothelial cell dysfunction. Kawakami A, Osaka M, Tani M, Azuma H, Sacks FM, Shimokado K, Yoshida M, Circulation 2008 118 7 731 742 10.1161/CIRCULATIONAHA.108.784785 18663085
20. Apolipoprotein CIII induces monocyte chemoattractant protein-1 and interleukin 6 expression via Toll-like receptor 2 pathway in mouse adipocytes. Abe Y, Kawakami A, Osaka M, Uematsu S, Akira S, Shimokado K, Sacks FM, Yoshida M, Arterioscler Thromb Vasc Biol 2010 30 11 2242 2248 10.1161/ATVBAHA.110.210427 20829510
21. Deoxyribonucleic acid polymorphism in the apolipoprotein A-1-C-III gene cluster. Association with hypertriglyceridemia. Rees A, Stocks J, Sharpe CR, Vella MA, Shoulders CC, Katz J, Jowett NI, Baralle FE, Galton DJ, J Clin Invest 1985 76 3 1090 1095 10.1172/JCI112062 2995445 (Pubitemid 16225605)
22. Apolipoprotein C-III, a strong discriminant of coronary risk in men and a determinant of the metabolic syndrome in both genders. Onat A, Hergenc G, Sansoy V, Fobker M, Ceyhan K, Toprak S, Assmann G, Atherosclerosis 2003 168 1 81 89 10.1016/S0021-9150(03)00025-X 12732390 (Pubitemid 36555814)
23. Association between the -455T > C promoter polymorphism of the APOC3 gene and the metabolic syndrome in a multi-ethnic sample. Pollex RL, Ban MR, Young TK, Bjerregaard P, Anand SS, Yusuf S, Zinman B, Harris SB, Hanley AJ, Connelly PW, BMC Med Genet 2007 8 80 18096054
24. Apolipoprotein C-III and the metabolic basis for hypertriglyceridemia and the dense low-density lipoprotein phenotype. Zheng C, Khoo C, Furtado J, Sacks FM, Circulation 2010 121 15 1722 1734 10.1161/CIRCULATIONAHA.109.875807 20368524
25. Abdominal obesity and hyperglycemia mask the effect of a common APOC3 haplotype on the risk of myocardial infarction. Ruiz-Narvaez EA, Sacks FM, Campos H, Am J Clin Nutr 2008 87 6 1932 1938 18541587 (Pubitemid 351872661)
26. Apolipoprotein C-III, n-3 polyunsaturated fatty acids, and "insulin-resistant" T-455C APOC3 gene polymorphism in heart disease patients: example of gene-diet interaction. Olivieri O, Martinelli N, Sandri M, Bassi A, Guarini P, Trabetti E, Pizzolo F, Girelli D, Friso S, Pignatti PF, Corrocher R, Clin Chem 2005 51 2 360 367 10.1373/clinchem.2004.040477 15576429 (Pubitemid 40175806)