Isolation of a novel macrocyclic dilactoneJBIR-101from Promicromonospora sp. RL26

Journal of Antibiotics

Volumn 64, Issue 10, 2011, Pages 689-691

  Izumikawa, Miho ^a   Takagi, Motoki ^a   Shin Ya, Kazuo ^b  

^a Koto ku   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

cytotoxicity; macrocyclic dilactone; malignant pleural mesothelioma; mangrove soil; Promicromonospora

Indexed keywords

CYTOTOXIC AGENT; JBIR 101; LACTONE DERIVATIVE; MACROCYCLIC COMPOUND; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; COLORIMETRY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; FEMALE; FUNGAL STRAIN; HELA CELL; HUMAN; HUMAN CELL; IC 50; MICROMONOSPORA; MYCELIUM; NOTE; PRIORITY JOURNAL; PROMICROMONOSPORA; STEREOCHEMISTRY;

PROMICROMONOSPORA;

EID: 80155146839     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2011.71     Document Type: Note

References (18)

1. Li, J. W.-H. & Vederas, J. C. Drug discovery and natural products: end of an era or an endless frontier? Science 325, 161-165 (2009).
2. Carbone, M., Kratzke, R. A. & Testa, J. R. The pathogenesis of mesothelioma. Semin. Oncol. 29, 2-17 (2002). (Pubitemid 34163530)
3. Mossman, B. T., Kamp, D. W. & Weitzman, S. A. Mechanisms of carcinogenesis and clinical features of asbestos-associated cancers. Cancer Invest. 14, 466-480 (1996). (Pubitemid 26338211)
4. Sekido, Y. Genomic abnormalities and signal transduction dysregulation in malignant mesothelioma cells. Cancer Sci. 101, 1-6 (2010).
5. Motohashi, K., Hwang, J.-H., Sekido, Y., Takagi, M. & Shin-ya, K. JBIR-23 and-24, novel anticancer agents from Streptomyces sp. AK-AB27. Org. Lett. 11, 285-288 (2009).
6. Hwang, J.-H., Takagi, M., Murakami, H., Sekido, Y. & Shin-ya, K. Induction of tubulin polymerization and apoptosis in malignant mesothelioma cells by a new compound JBIR-23. Cancer Lett. 300, 189-196 (2011).
7. Izumikawa, M., Khan, S. T., Komaki, H., Takagi, M. & Shin-ya, K. JBIR-31, a new teleocidin analog, produced by salt-requiring Streptomyces sp. NBRC 105896 isolated from a marine sponge. J. Antibiot. 63, 33-36 (2010).
8. Ueda, J., Takagi, M. & Shin-ya, K. Aminocaprophenone-and pyrrolidine-type alkaloids from the leaves of Ficus septica. J. Nat. Prod. 72, 2181-2183 (2009).
9. Motohashi, K., Takagi, M., Yamamura, H., Hayakawa, M. & Shin-ya, K. A new angucycline and a new butenolide isolated from lichen-derived Streptomyces spp. J. Antibiot. 63, 545-548 (2010).
10. Ueda, J. et al. New angucycline C-glycosides from Streptomyces sp. RI33. J. Antibiot. 64, 367-372 (2011).
11. Ueda, J., Takagi, M. & Shin-ya, K. New xanthoquinodin-like compounds, JBIR-97,-98 and-99, obtained from marine sponge-derived fungus Tritirachium sp. SpB081112MEf2. J. Antibiot. 63, 615-618 (2010).
12. Furihata, K. & Seto, H. Constant time HMBC (CT-HMBC), a new HMBC technique useful for improving separation of cross peaks. Tetrahedron Lett. 39, 7337-7340 (1998). (Pubitemid 28545060)
13. Kasai, R., Okihara, M., Asakawa, J., Mizukami, K. & Tanaka, O. 13C NMR study of aand b-anomeric pairs of D-mannopyranosides and L-rhamnopyranosides. Tetrahedron 35, 1427-1432 (1979).
14. Windholz, M. The Merck Index 10th edn, 638-639 Merck & Co., Inc., Rahway, 1983.
15. Tsunakawa, M. et al. New antiviral antibiotics, cycloviracins B1 and B2. I. Production, isolation, physico-chemical properties and biological activity. J. Antibiot. 45, 1467-1471 (1992).
16. Tsunakawa, M. et al. New antiviral antibiotics, cycloviracins B1 and B2. II. Structure determination. J. Antibiot. 45, 1472-1479 (1992).
17. Qian-Cutrone, J. et al. Glucolipsin A and B, two new glucokinase activators produced by Streptomyces purpurogeniscleroticus and Nocardia vaccinii. J. Antibiot. 52, 245-255 (1999). (Pubitemid 29160979)
18. Usami, N. et al. Establishment and characterization of four malignant pleural mesothelioma cell lines from Japanese patients. Cancer Sci. 97, 387-394 (2006).