메뉴 건너뛰기




Volumn 10, Issue 3, 2011, Pages 165-174

Prediction and prevention of schizophrenia: What has been achieved and where to go next?

Author keywords

Basic symptoms; Differentiated prevention; Early course; High risk symptoms; Risk factors; Risk staging; Schizophrenia

Indexed keywords

AMISULPRIDE; ARIPIPRAZOLE; OLANZAPINE; RISPERIDONE;

EID: 80155145244     PISSN: 17238617     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.2051-5545.2011.tb00044.x     Document Type: Review
Times cited : (105)

References (68)
  • 2
    • 0004060047 scopus 로고    scopus 로고
    • Commonwealth Department of Health and Aged Care. Canberra: Commonwealth Department of Health and Aged Care
    • Commonwealth Department of Health and Aged Care. Promotion, prevention and early intervention for mental health - a monograph. Canberra: Commonwealth Department of Health and Aged Care, 2000.
    • (2000) Promotion, Prevention and Early Intervention for Mental Health - A Monograph
  • 7
    • 10844228996 scopus 로고    scopus 로고
    • Kosten der fruhverrentung am beispiel der schizophrenie
    • DOI 10.1055/s-2004-828476
    • Clouth J. Costs of early retirement - the case of schizophrenia. Psychiatr Prax 2004;31(Suppl. 2):S238-45. (Pubitemid 40007470)
    • (2004) Psychiatrische Praxis, Supplement , vol.31 , Issue.2
    • Clouth, J.1
  • 8
    • 19844380572 scopus 로고    scopus 로고
    • Size of burden of schizophrenia and psychotic disorders
    • DOI 10.1016/j.euroneuro.2005.04.009, PII S0924977X05000726, Size and Burden of Mental Disorders in Europe
    • Rössler W, Salize HJ, van Os J et al. Size of burden of schizophrenia and psychotic disorders. Eur Neuropsychopharmacol 2005;15:399-409. (Pubitemid 40943544)
    • (2005) European Neuropsychopharmacology , vol.15 , Issue.4 , pp. 399-409
    • Rossler, W.1    Joachim, S.H.2    Van Os, J.3    Riecher-Rossler, A.4
  • 9
    • 77954218827 scopus 로고    scopus 로고
    • The economics of schizophrenia
    • Mueser KT, Jeste DV (eds). New York: Guilford
    • Samnaliev M, Clark RE. The economics of schizophrenia. In: Mueser KT, Jeste DV (eds). Clinical handbook of schizophrenia. New York: Guilford, 2008:507-15.
    • (2008) Clinical Handbook of Schizophrenia , pp. 507-515
    • Samnaliev, M.1    Clark, R.E.2
  • 11
    • 12344327212 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence
    • DOI 10.1038/sj.mp.4001558
    • Harrison PJ, Weinberger DR. Schizophrenia genes, gene expression and neuropathology on the matter of their convergence. Mol Psychiatry 2005;10(Suppl. 3):40-68. (Pubitemid 40139588)
    • (2005) Molecular Psychiatry , vol.10 , Issue.1 , pp. 40-68
    • Harrison, P.J.1    Weinberger, D.R.2
  • 12
    • 77953316957 scopus 로고    scopus 로고
    • Neuropsychology of the prodrome to psychosis in the NAPLS consortium: Relationship to family history and conversion to psychosis
    • Seidman LJ, Giuliano AJ, Meyer EC et al. Neuropsychology of the prodrome to psychosis in the NAPLS consortium: relationship to family history and conversion to psychosis. Arch Gen Psychiatry 2010;67:578-88.
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 578-588
    • Seidman, L.J.1    Giuliano, A.J.2    Meyer, E.C.3
  • 13
    • 68949180394 scopus 로고    scopus 로고
    • Schizophrenia
    • van Os J, Kapur S. Schizophrenia. Lancet 2009;374:635-45.
    • (2009) Lancet , vol.374 , pp. 635-645
    • Van Os, J.1    Kapur, S.2
  • 15
    • 73949110927 scopus 로고    scopus 로고
    • Basic symptoms and ultrahigh risk criteria: Symptom development in the initial prodromal state
    • Schultze-Lutter F, Ruhrmann S, Berning J et al. Basic symptoms and ultrahigh risk criteria: symptom development in the initial prodromal state. Schizophr Bull 2010;36:182-91.
    • (2010) Schizophr Bull , vol.36 , pp. 182-191
    • Schultze-Lutter, F.1    Ruhrmann, S.2    Berning, J.3
  • 16
    • 0347003610 scopus 로고    scopus 로고
    • Early Detection and Intervention in the Initial Prodromal Phase of Schizophrenia
    • Ruhrmann S, Schultze-Lutter F, Klosterkötter J. Early detection and intervention in the initial prodromal phase of schizophrenia. Pharmacopsychiatry 2003;36(Suppl. 3):S162-7. (Pubitemid 38085132)
    • (2003) Pharmacopsychiatry , vol.36 , Issue.SUPPL. 3
    • Ruhrmann, S.1    Schultze-Lutter, F.2    Klosterkotter, J.3
  • 17
    • 24344441586 scopus 로고    scopus 로고
    • Association between duration of untreated psychosis and outcome in cohorts of first-episode patients: A systematic review
    • DOI 10.1001/archpsyc.62.9.975
    • Marshall M, Lewis S, Lockwood A et al. Association between duration of untreated psychosis and outcome in cohorts of first-episode patients: a systematic review. Arch Gen Psychiatry 2005;62:975-83. (Pubitemid 41248376)
    • (2005) Archives of General Psychiatry , vol.62 , Issue.9 , pp. 975-983
    • Marshall, M.1    Lewis, S.2    Lockwood, A.3    Drake, R.4    Jones, P.5    Croudace, T.6
  • 19
    • 0024848601 scopus 로고
    • The concept of basic symptoms in schizophrenic and schizoaffective psychoses
    • Huber G, Gross G. The concept of basic symptoms in schizophrenic and schizoaffective psychoses. Recent Prog Med 1989;80:646-52.
    • (1989) Recent Prog Med , vol.80 , pp. 646-652
    • Huber, G.1    Gross, G.2
  • 20
    • 0024758890 scopus 로고
    • The 'basic' symptoms of schizophrenia
    • Gross G. The 'basic' symptoms of schizophrenia. Br J Psychiatry 1989;7:21-5. (Pubitemid 19270843)
    • (1989) British Journal of Psychiatry , vol.155 , Issue.NOV. SUPPL. 7 , pp. 21-25
    • Gross, G.1
  • 24
    • 77953521827 scopus 로고    scopus 로고
    • The dimensional structure of self-reported 'prodromal' disturbances in schizophrenia
    • Schultze-Lutter F, Steinmeyer EM, Ruhrmann S et al. The dimensional structure of self-reported 'prodromal' disturbances in schizophrenia. Clin Neuropsychiatry 2008;5:140-50.
    • (2008) Clin Neuropsychiatry , vol.5 , pp. 140-150
    • Schultze-Lutter, F.1    Steinmeyer, E.M.2    Ruhrmann, S.3
  • 28
    • 0034320484 scopus 로고    scopus 로고
    • Identification of young people at risk of psychosis: Validation of personal assessment and crisis evaluation clinic intake criteria
    • Phillips LJ, Yung AR, McGorry PD. Identification of young people at risk of psychosis: validation of personal assessment and crisis evaluation clinic intake criteria. Aust N Z J Psychiatry 2000;34:S164-9.
    • (2000) Aust N Z J Psychiatry , vol.34
    • Phillips, L.J.1    Yung, A.R.2    McGorry, P.D.3
  • 30
    • 0036241144 scopus 로고    scopus 로고
    • Prospective diagnosis of the initial prodrome for schizophrenia based on the structured interview for prodromal syndromes: Preliminary evidence of interrater reliability and predictive validity
    • DOI 10.1176/appi.ajp.159.5.863
    • Miller TJ, McGlashan TH, Rosen JL et al. Prospective diagnosis of the initial prodrome for schizophrenia based on the structured interview for prodromal syndromes: preliminary evidence of interrater reliability and predictive validity. Am J Psychiatry 2002;159:863-5. (Pubitemid 34465065)
    • (2002) American Journal of Psychiatry , vol.159 , Issue.5 , pp. 863-865
    • Miller, T.J.1    McGlashan, T.H.2    Rosen, J.L.3    Somjee, L.4    Markovich, P.J.5    Stein, K.6    Woods, S.W.7
  • 32
    • 0037045148 scopus 로고    scopus 로고
    • The New York high risk project to the Hillside recognition and prevention (RAP) program
    • DOI 10.1002/ajmg.b.10520
    • Cornblatt B. The New York High-Risk Project to the Hillside Recognition and Prevention (RAP) Program. Am J Med Genet 2002; 114:956-66. (Pubitemid 35379240)
    • (2002) American Journal of Medical Genetics - Neuropsychiatric Genetics , vol.114 , Issue.8 , pp. 956-966
    • Cornblatt, B.A.1
  • 34
    • 33745584552 scopus 로고    scopus 로고
    • Testing the Ultra High Risk (prodromal) criteria for the prediction of psychosis in a clinical sample of young people
    • DOI 10.1016/j.schres.2006.03.014, PII S0920996406001083
    • Yung AR, Stanford C, Cosgrave E et al. Testing the ultra high risk (prodromal) criteria for the prediction of psychosis in a clinical sample of young people. Schizophr Res 2006;84:57-66. (Pubitemid 44255719)
    • (2006) Schizophrenia Research , vol.84 , Issue.1 , pp. 57-66
    • Yung, A.R.1    Stanford, C.2    Cosgrave, E.3    Killackey, E.4    Phillips, L.5    Nelson, B.6    McGorry, P.D.7
  • 35
    • 52949151529 scopus 로고    scopus 로고
    • Validation of "prodromal" criteria to detect individuals at ultra high risk of psychosis: 2 Year follow-up
    • Yung AR, Nelson B, Stanford C et al. Validation of "prodromal" criteria to detect individuals at ultra high risk of psychosis: 2 year follow-up. Schizophr Res 2008;105:10-7.
    • (2008) Schizophr Res , vol.105 , pp. 10-17
    • Yung, A.R.1    Nelson, B.2    Stanford, C.3
  • 36
    • 69249151641 scopus 로고    scopus 로고
    • Validity of the prodromal risk syndrome for first psychosis: Findings from the North American Prodrome Longitudinal Study
    • Woods SW, Addington J, Cadenhead KS et al. Validity of the prodromal risk syndrome for first psychosis: findings from the North American Prodrome Longitudinal Study. Schizophr Bull 2009;35:894-908.
    • (2009) Schizophr Bull , vol.35 , pp. 894-908
    • Woods, S.W.1    Addington, J.2    Cadenhead, K.S.3
  • 38
    • 4944260378 scopus 로고    scopus 로고
    • Risk factors for transition to first episode psychosis among individuals with 'at-risk mental states'
    • DOI 10.1016/j.schres.2004.04.006, PII S0920996404001537
    • Mason O, Startup M, Halpin S et al. Risk factors for transition to first episode psychosis among individuals with 'at-risk mental states'. Schizophr Res 2004;71:227-37. (Pubitemid 39330501)
    • (2004) Schizophrenia Research , vol.71 , Issue.2-3 , pp. 227-237
    • Mason, O.1    Startup, M.2    Halpin, S.3    Schall, U.4    Conrad, A.5    Carr, V.6
  • 39
    • 1342343074 scopus 로고    scopus 로고
    • Risk factors for psychosis in an ultra high-risk group: Psychopathology and clinical features
    • DOI 10.1016/S0920-9964(03)00192-0
    • Yung AR, Phillips LJ, Yuen HP et al. Risk factors for psychosis in an ultra high-risk group: psychopathology and clinical features. Schizophr Res 2004;67:131-42. (Pubitemid 38251443)
    • (2004) Schizophrenia Research , vol.67 , Issue.2-3 , pp. 131-142
    • Yung, A.R.1    Phillips, L.J.2    Yuen, H.P.3    McGorry, P.D.4
  • 40
    • 38049108277 scopus 로고    scopus 로고
    • Prediction of psychosis in youth at high clinical risk: A multisite longitudinal study in North America
    • Cannon TD, Cadenhead K, Cornblatt B et al. Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America. Arch Gen Psychiatry 2008;65:28-37.
    • (2008) Arch Gen Psychiatry , vol.65 , pp. 28-37
    • Cannon, T.D.1    Cadenhead, K.2    Cornblatt, B.3
  • 41
    • 77649201030 scopus 로고    scopus 로고
    • Prediction of psychosis in adolescents and young adults at high risk: Results from the prospective European Prediction of Psychosis Study (EPOS)
    • Ruhrmann S, Schultze-Lutter F, Salokangas RK et al. Prediction of psychosis in adolescents and young adults at high risk: results from the prospective European Prediction of Psychosis Study (EPOS). Arch Gen Psychiatry 2010;67:241-51.
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 241-251
    • Ruhrmann, S.1    Schultze-Lutter, F.2    Salokangas, R.K.3
  • 44
    • 0036791949 scopus 로고    scopus 로고
    • Randomized controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms
    • McGorry PD, Yung AR, Phillips LJ et al. Randomized controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms. Arch Gen Psychiatry 2002;59:921-8
    • (2002) Arch Gen Psychiatry , vol.59 , pp. 921-928
    • McGorry, P.D.1    Yung, A.R.2    Phillips, L.J.3
  • 45
    • 34848918455 scopus 로고    scopus 로고
    • Medium term follow-up of a randomized controlled trial of interventions for young people at ultra high risk of psychosis
    • DOI 10.1016/j.schres.2007.05.018, PII S092099640700240X
    • Phillips LJ, McGorry PD, Yuen HP et al. Medium-term follow-up of a randomized controlled trial of interventions for young people at ultra high risk of psychosis. Schizophr Res 2007;96:25-33. (Pubitemid 47494628)
    • (2007) Schizophrenia Research , vol.96 , Issue.1-3 , pp. 25-33
    • Phillips, L.J.1    McGorry, P.D.2    Yuen, H.P.3    Ward, J.4    Donovan, K.5    Kelly, D.6    Francey, S.M.7    Yung, A.R.8
  • 47
    • 34548048405 scopus 로고    scopus 로고
    • Three-year follow-up of a randomized controlled trial of cognitive therapy for the prevention of psychosis in people at ultrahigh risk
    • DOI 10.1093/schbul/sbl042
    • Morrison AP, French P, Parker S et al. Three-year follow-up of a randomized controlled trial of cognitive therapy for the prevention of psychosis in people at ultrahigh risk. Schizophr Bull 2007;33:682-7. (Pubitemid 47343709)
    • (2007) Schizophrenia Bulletin , vol.33 , Issue.3 , pp. 682-687
    • Morrison, A.P.1    French, P.2    Parker, S.3    Roberts, M.4    Stevens, H.5    Bentall, R.P.6    Lewis, S.W.7
  • 50
    • 80052241700 scopus 로고    scopus 로고
    • Preventing progression to first-episode psychosis in early initial prodromal states
    • in press
    • Bechdolf A, Wagner M, Harrigan S et al. Preventing progression to first-episode psychosis in early initial prodromal states. Br J Psychiatry (in press).
    • Br J Psychiatry
    • Bechdolf, A.1    Wagner, M.2    Harrigan, S.3
  • 51
    • 11844279765 scopus 로고    scopus 로고
    • Pharmacological intervention in the initial prodromal phase of psychosis
    • DOI 10.1016/j.eurpsy.2004.11.001, PII S0924933804002640
    • Ruhrmann S, Schultze-Lutter F, Maier W et al. Pharmacological intervention in the initial prodromal phase of psychosis. Eur Psychiatry 2005;20:1-6. (Pubitemid 40092385)
    • (2005) European Psychiatry , vol.20 , Issue.1 , pp. 1-6
    • Ruhrmann, S.1    Schultze-Lutter, F.2    Maier, W.3    Klosterkotter, J.4
  • 52
    • 85038520626 scopus 로고    scopus 로고
    • Rationale and baseline characteristics of PREVENT: A second generation intervention trial in subjects at-risk (prodromal) of developing first episode psychosis evaluating cognitive behaviour therapy, aripiprazole and placebo for the prevention of psychosis
    • in press
    • Bechdolf A, Müller H, Stützer H et al. Rationale and baseline characteristics of PREVENT: a second generation intervention trial in subjects at-risk (prodromal) of developing first episode psychosis evaluating cognitive behaviour therapy, aripiprazole and placebo for the prevention of psychosis. Schizophr Bull (in press).
    • Schizophr Bull
    • Bechdolf, A.1    Müller, H.2    Stützer, H.3
  • 53
    • 37249047375 scopus 로고    scopus 로고
    • Aripiprazole in the treatment of the psychosis prodrome. An open-label pilot study
    • Woods SW, Tully EM, Walsh BC et al. Aripiprazole in the treatment of the psychosis prodrome. An open-label pilot study. Br J Psychiatry 2007;191(Suppl. 51):96-101.
    • (2007) Br J Psychiatry , vol.191 , Issue.SUPPL. 51 , pp. 96-101
    • Woods, S.W.1    Tully, E.M.2    Walsh, B.C.3
  • 55
    • 77954239263 scopus 로고    scopus 로고
    • Biomarkers for Alzheimer's disease: Academic, industry and regulatory perspectives
    • Hampel H, Frank R, Broich K et al. Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives. Nat Rev Drug Discov 2010;9:560-74.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 560-574
    • Hampel, H.1    Frank, R.2    Broich, K.3
  • 56
    • 36148988271 scopus 로고    scopus 로고
    • Structural brain abnormalities in individuals with an at-risk mental state who later develop psychosis
    • Borgwardt SJ, McGuire PK, Aston J et al. Structural brain abnormalities in individuals with an at-risk mental state who later develop psychosis. Br J Psychiatry 2007;191(Suppl. 51):69-75.
    • (2007) Br J Psychiatry , vol.191 , Issue.SUPPL. 51 , pp. 69-75
    • Borgwardt, S.J.1    McGuire, P.K.2    Aston, J.3
  • 57
    • 48749093404 scopus 로고    scopus 로고
    • Sensory gating in schizophrenia: P50 and N100 gating in antipsychotic-free subjects at risk, first-episode, and chronic patients
    • Brockhaus-Dumke A, Schultze-Lutter F, Mueller R et al. Sensory gating in schizophrenia: P50 and N100 gating in antipsychotic-free subjects at risk, first-episode, and chronic patients. Biol Psychiatry 2008;64:376-84.
    • (2008) Biol Psychiatry , vol.64 , pp. 376-384
    • Brockhaus-Dumke, A.1    Schultze-Lutter, F.2    Mueller, R.3
  • 58
    • 34547646311 scopus 로고    scopus 로고
    • Neuroimaging and emerging psychotic disorders: The Melbourne ultra-high risk studies
    • Pantelis C, Velakoulis D, Wood SJ et al. Neuroimaging and emerging psychotic disorders: the Melbourne ultra-high risk studies. Int Rev Psychiatry 2007;19:371-81.
    • (2007) Int Rev Psychiatry , vol.19 , pp. 371-381
    • Pantelis, C.1    Velakoulis, D.2    Wood, S.J.3
  • 60
    • 68949209644 scopus 로고    scopus 로고
    • Gray matter abnormalities in subjects at ultra-high risk for schizophrenia and first-episode schizophrenic patients compared to healthy controls
    • Witthaus H, Kaufmann C, Bohner G et al. Gray matter abnormalities in subjects at ultra-high risk for schizophrenia and first-episode schizophrenic patients compared to healthy controls. Psychiatry Res 2008;173:163-9.
    • (2008) Psychiatry Res , vol.173 , pp. 163-169
    • Witthaus, H.1    Kaufmann, C.2    Bohner, G.3
  • 61
    • 52649168263 scopus 로고    scopus 로고
    • Schizophrenia aetiology: Do gene-environment interactions hold the key?
    • The European Network of Schizophrenia Networks for the Study of Gene-Environment Interactions (EU-GEI)
    • The European Network of Schizophrenia Networks for the Study of Gene-Environment Interactions (EU-GEI). Schizophrenia aetiology: do gene-environment interactions hold the key? Schizophr Res 2008;102:21-6.
    • (2008) Schizophr Res , vol.102 , pp. 21-26
  • 62
    • 77954216616 scopus 로고    scopus 로고
    • Probably at-risk, but certainly ill - Advocating the introduction of a psychosis spectrum disorder in DSM-V
    • Ruhrmann S, Schultze-Lutter F, Klosterkötter J. Probably at-risk, but certainly ill - Advocating the introduction of a psychosis spectrum disorder in DSM-V. Schizophr Res 2010;120:23-37.
    • (2010) Schizophr Res , vol.120 , pp. 23-37
    • Ruhrmann, S.1    Schultze-Lutter, F.2    Klosterkötter, J.3
  • 63
    • 62449264425 scopus 로고    scopus 로고
    • Neuroprotection: A new strategy in the treatment of schizophrenia. Neurobiological basis of neurodegeneration and neuroprotection
    • Lieberman JA. Neuroprotection: a new strategy in the treatment of schizophrenia. Neurobiological basis of neurodegeneration and neuroprotection. CNS Spectr 2007;12(Suppl. 18):4-6.
    • (2007) CNS Spectr , vol.12 , Issue.SUPPL. 18 , pp. 4-6
    • Lieberman, J.A.1
  • 65
    • 76149102249 scopus 로고    scopus 로고
    • Long-chain omega-3 fatty acids for indicated prevention of psychotic disorders: A randomized, placebo-controlled trial
    • Amminger GP, Schäfer MR, Papageorgiou K et al. Long-chain omega-3 fatty acids for indicated prevention of psychotic disorders: a randomized, placebo-controlled trial. Arch Gen Psychiatry 2010;67:146-54.
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 146-154
    • Amminger, G.P.1    Schäfer, M.R.2    Papageorgiou, K.3
  • 67
    • 62449087550 scopus 로고    scopus 로고
    • Neuroprotective effects of low dose lithium in individuals at ultra-high risk for psychosis. A longitudinal MRI/MRS study
    • Berger G, Wood SJ, Dell'Olio M et al. Neuroprotective effects of low dose lithium in individuals at ultra-high risk for psychosis. A longitudinal MRI/MRS study. Schizophr Res 2008;102:39-40.
    • (2008) Schizophr Res , vol.102 , pp. 39-40
    • Berger, G.1    Wood, S.J.2    Dell'Olio, M.3
  • 68
    • 80155132780 scopus 로고    scopus 로고
    • The NEURAPRO (North America, Europe, Australia Prodrome) Study: A multicenter RCT of treatment strategies for symptomatic patients at ultra-high risk for progression to schizophrenia and related disorders. Design and study plan
    • Nelson B, McGorry P, Yung A et al. The NEURAPRO (North America, Europe, Australia Prodrome) Study: a multicenter RCT of treatment strategies for symptomatic patients at ultra-high risk for progression to schizophrenia and related disorders. Design and study plan. Schizophr Res 2008;102(Suppl. 2):295.
    • (2008) Schizophr Res , vol.102 , Issue.SUPPL. 2 , pp. 295
    • Nelson, B.1    McGorry, P.2    Yung, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.