A critical look at phenytoin use for early post-traumatic seizure prophylaxis

Canadian Journal of Neurological Sciences

Volumn 38, Issue 6, 2011, Pages 896-901

  Debenham, Sierra ^e   Sabit, Behzad ^a   Saluja, Rajeet ^b   Lamoureux, Julie ^d   Bajsarowicz, Paul ^c   Maleki, Mohammad ^a   Marcoux, Judith ^a  

^a MONTREAL GENERAL HOSPITAL   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c Faculte de Medecine   (Canada)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

^e BRIGHAM YOUNG UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMAZEPINE; PHENYTOIN;

ARTICLE; BRADYCARDIA; COMPUTER ASSISTED TOMOGRAPHY; DRUG EFFICACY; DRUG OVERDOSE; DRUG UNDERDOSE; DRUG USE; ERYTHEMA; GLASGOW COMA SCALE; HUMAN; LOADING DRUG DOSE; MAINTENANCE DRUG DOSE; MAJOR CLINICAL STUDY; MEDICAL DECISION MAKING; PATIENT COMPLIANCE; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROPHYLAXIS; PRURITUS; SEIZURE; TRAUMATIC BRAIN INJURY;

EID: 80155142470     PISSN: 03171671     EISSN: None     Source Type: Journal    
DOI: 10.1017/S031716710001249X     Document Type: Article

References (27)

1. Ministry of Health Services and Ministry of Health Planning. Guidelines for planning brain injury services and supports in British Columbia. Victoria, BC. 2002 January. Available from: http://www.health.gov.bc.ca/library/ publications/year/2002/MH A Brain Injury Guidelines.pdf
2. Centers for Disease Control and Prevention.gov[homepage on the Internet]. Centers for Disease Control and Prevention 1600 Clifton Rd. Atlanta, GA 30333, USA [updated 2011 May 5; reviewed 2010 March 8]. Available from: http://www.cdc.gov/ncipc/tbi/TBI.htm
3. Agrawal A, Timothy J, Pandit L, Manju M. Post-traumatic epilepsy: an overview. Clin Neurol Neurosur. 2006;108:433-9.
4. Temkin NR, Dikmen SS, Wilensky AJ, Keihm J, Chabal S, Winn HR. A randomized, double-blind study of phenytoin for the prevention of post-traumatic seizures. N Engl J Med. 1990;323: 497-502. (Pubitemid 20260049)
5. Schierhout G, Roberts I. Anti-epileptic drugs for preventing seizures following acute traumatic brain injury. Cochrane DB Syst Rev. 2001;CD000173. Review.
6. Bao YH, Bramlett HM, Atkins CM, et al. Post-traumatic seizures exacerbate histopathological damage after fluid-percussion brain injury. J Neurotraum. 2011;28:35-42.
7. Weiss GH, Feeney DM, Caveness WF, et al. Prognostic factors for the occurrence of posttraumatic epilepsy. Arch Neurol. 1983;40: 7-10. (Pubitemid 13162905)
8. Asikainen I, Kaste M, Sarna S. Early and late posttraumatic seizures in traumatic brain injury rehabilitation patients: brain injury factors causing late seizures and influence of seizures on long-term outcome. Epilepsia. 1999;40:584-9. (Pubitemid 29207322)
9. Iudice A, Murri L. Pharmacological prophylaxis of post-traumatic epilepsy. Drugs. 2000;59:1091-9. (Pubitemid 30339135)
10. Teasell R, Bayona N, Lippert C, Villamere J, Hellings C. Posttraumatic seizure disorder following acquired brain injury. Brain Injury. 2007;21:201-14. (Pubitemid 46443632)
11. Chang BS, Lowenstein DH. Practice parameter: Antiepileptic drug prophylaxis in severe traumatic brain injury: report of the quality standards subcommittee of the American Academy of Neurology. Neurology. 2003;60:10-16. (Pubitemid 36070636)
12. Brain Trauma Foundation Guidelines. Role of antiseizure prophylaxis following head injury. J Neurotraum. 2007;suppl 1: S83-S6.
13. Jacka MJ, Zygun D. Survey of management of severe head injury in Canada. Can J Neurol Sci. 2007;34(3):307-12. (Pubitemid 47359833)
14. Teasdale G. Jennett B. Assessment of coma and impaired consciousness: a practical scale. Lancet. 1974;13:81-4.
15. Marshall LF, Eisenberg HM, Jane JA. A new classification of head injury based on computerized tomography. J Neurosurg. 1991; 75:S14-20.
16. Marshall LF, Marshall SB, Klauber MR, et al. The diagnosis of head injury requires a classification based on computed axial tomography. J Neurotraum. 1992;9:S287-92.
17. Liberman M, Mulder DS, Lavoie A, Sampalis JS. Implementation of a trauma care system: evolution through evaluation. J Traum. 2004;56:1330-5. (Pubitemid 38901850)
18. Englander J, Bushnik T, Duong TT, et al. Analyzing risk factors for late posttraumatic seizures: a prospective, multicenter investigation. Arch Phys Med Rehabil. 2003;84:365-73. (Pubitemid 36297735)
19. Saboori M, Ahmadi J, Farajzadegan Z. Indications for brain CT scan in patients with minor head injury. Clin Neurol Neurosurg. 2007;109:399-405. (Pubitemid 46660324)
20. Franko J, Kish KJ, O'Connell BG, Subramanian S, Yuschak JV. Advanced age and preinjury warfarin anticoagulation increase the risk of mortality after head trauma. J Traum. 2006;61: 107-10. (Pubitemid 44098325)
21. Borczuk P. Predictors of intracranial injury in patients with mild head trauma. Ann Emerg Med. 1995;25:731-6.
22. Schynoll W, Overton D, Krome R, et al. A prospective study to identify high-yield criteria associated with acute intracranial computed tomography findings in head-injured patients. Am J Emerg Med. 1993;11:321-6. (Pubitemid 23227904)
23. Gutman MB, Moulton RJ, Sullivan I, Hotz G, Tucker WS, Muller PJ. Risk factors predicting operable intracranial hematomas in head injury. J Neurosurg. 1992;77:9-14.
24. Grisar T, Bottin P, Borchgrave d'Alténa V, et al. Prophylaxis of the epilepsies: should anti-epileptic drugs be used for preventing seizures after acute brain injury? Acta Neurol Belg. 2005;105: 5-13. (Pubitemid 40542356)
25. Khan AA, Banerjee A. The role of prophylactic anticonvulsants in moderate to severe head injury. Int J Emerg Med. 2010;3: 187-91.
26. Darrah SD, Chuang J, Mohler LM, et al. Dilantin therapy in an experimental model of traumatic brain injury: effects of limited versus daily treatment on neurological and behavioral recovery. J Neurotraum. 2011;28:43-55.
27. Hess DR. Retrospective studies and chart reviews. Respir Care. 2004;49:1171-4.