Postoperative complications following the Fontan procedure: The role of aprotinin

Perfusion

Volumn 26, Issue 6, 2011, Pages 529-535

  Klugman, D ^a   Donofrio, M T ^b   Zurakowski, D ^c   Jonas, R A ^b  

^a GEORGE WASHINGTON UNIVERSITY   (United States)

^b GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

aprotinin; arrhythmia; chest tube drainage; Fontan; pleural effusion

Indexed keywords

ANTIINFLAMMATORY AGENT; APROTININ;

ADOLESCENT; ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD VOLUME; CHILD; CONTINUOUS INFUSION; CONTROLLED STUDY; FEMALE; FENESTRATION; FONTAN PROCEDURE; HEART ARRHYTHMIA; HUMAN; INTRAOPERATIVE PERIOD; KIDNEY DYSFUNCTION; KIDNEY FUNCTION; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; OUTCOME ASSESSMENT; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PERIOD; POSTOPERATIVE THROMBOSIS; PREOPERATIVE PERIOD; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; THORAX DRAINAGE; TREATMENT DURATION;

ADOLESCENT; APROTININ; ARRHYTHMIAS, CARDIAC; CHILD; CHILD, PRESCHOOL; DRAINAGE; FEMALE; FONTAN PROCEDURE; HEMOSTATICS; HUMANS; INFANT; MALE; PLEURAL EFFUSION; POSTOPERATIVE COMPLICATIONS;

EID: 80155136233     PISSN: 02676591     EISSN: 1477111X     Source Type: Journal    
DOI: 10.1177/0267659111416877     Document Type: Article

References (25)

1. Fontan F, Baudet E. Surgical repair of tricuspid atresia. Thorax. 1971 ; 26: 240-248
2. de Leval MR, Dubini G, Migliavacca F, et al. Use of computational fluid dynamics in the design of surgical procedures: application to the study of competitive flows in cavo-pulmonary connections. J Thorac Cardiovasc Surg. 1996 ; 111: 502-513 (Pubitemid 26087713)
3. Van Haesdonck JM, Mertens L, Sizaire R, et al. Comparison by computerized numeric modeling of energy losses in different Fontan connections. Circulation. 1995 ; 92: II322-326
4. de Leval MR, Kilner P, Gewillig M, Bull C. Total cavopulmonary connection: a logical alternative to atriopulmonary connection for complex Fontan operations. Experimental studies and early clinical experience. J Thorac Cardiovasc Surg. 1988 ; 96: 682-695
5. Jonas RA, Castaneda AR. Modified Fontan procedure: atrial baffle and systemic venous to pulmonary artery anastomotic techniques. J Card Surg. 1988 ; 3: 91-96
6. Bridges ND, Mayer JE, Lock JE, et al. Effect of baffle fenestration on outcome of the modified Fontan operation. Circulation. 1992 ; 86: 1762-1769
7. Gentles TL, Mayer JE, Gauvreau K, et al. Fontan operation in five hundred consecutive patients: factors influencing early and late outcome. J Thorac Cardiovasc Surg. 1997 ; 114: 376-391 (Pubitemid 27400871)
8. Lemler MS, Scott WA, Leonard SR, Stromberg D, Ramaciotti C. Fenestration improves clinical outcome of the Fontan procedure: a prospective, randomized study. Circulation. 2002 ; 105: 207-212 (Pubitemid 34084320)
9. Gupta A, Daggett C, Behera S, et al. Risk factors for persistent pleural effusions after the extracardiac Fontan procedure. J Thorac Cardiovasc Surg. 2004 ; 127: 1664-1669 (Pubitemid 38725445)
10. McEvoy MD, Reeves ST, Reves JG, Spinale FG. Aprotinin in cardiac surgery: a review of conventional and novel mechanisms of action. Anesth Analg. 2007 ; 105: 949-962 (Pubitemid 47479307)
11. Royston D, Bidstrup BP, Taylor KM, Sapsford RN. Effect of aprotinin on need for blood transfusion after repeat open-heart surgery. Lancet. 1987 ; 2: 1289-1291 (Pubitemid 17156632)
12. Bidstrup BP, Royston D, Sapsford RN, Taylor KM. Reduction in blood loss and blood use after cardiopulmonary bypass with high dose aprotinin (Trasylol). J Thorac Cardiovasc Surg. 1989 ; 97: 364-372 (Pubitemid 19080881)
13. Davies MJ, Allen A, Kort H, et al. Prospective, randomized, double-blind study of high-dose aprotinin in pediatric cardiac operations. Ann Thorac Surg. 1997 ; 63: 497-503 (Pubitemid 27084580)
14. Mangano DT, Miao Y, Vuylsteke A, et al. Mortality associated with aprotinin during 5 years following coronary artery bypass graft surgery. JAMA. 2007 ; 297: 471-479
15. Mangano DT, Tudor IC, Dietzel C. The risk associated with aprotinin in cardiac surgery. N Engl J Med. 2006 ; 354: 353-365 (Pubitemid 43145060)
16. Rosner B Fundamentals of biostatistics. 6 th Edition, 2010, Belmont, CA: Brooks/Cole. Belmont, CA: Brooks/Cole ; 2010 :
17. Hosmer D, Cook ED, Lemeshow S Applied logistic regression 2nd Edition. New York: John Wiley ; 2001 :
18. Backer CL, Kelle AM, Stewart RD, et al. Aprotinin is safe in pediatric patients undergoing cardiac surgery. J Thorac Cardiovasc Surg. 2007 ; 134: 1421-1426
19. Stamm C, Friehs I, Mayer JE, et al. Long-term results of the lateral tunnel Fontan operation. J Thorac Cardiovasc Surg. 2001 ; 121: 28-41 (Pubitemid 32105320)
20. Casta A, Gruber EM, Laussen PC, McGowan FX, Odegard KC, et al. Parameters associated with perioperative baffle fenestration closure in the Fontan operation. J Cardiothorac Vasc Anesth. 2000 ; 14: 553-556
21. Gardiner HM, Dhillon R, Bull C, de Leval MR, Deanfield JE. Prospective study of the incidence and determinants of arrhythmia after total cavopulmonary connection. Circulation. 1996 ; 94: II17-21
22. Mainwaring RD, Lamberti JJ, Hugli TE. Complement activation and cytokine generation after modified Fontan procedure. Ann Thorac Surg. 1998 ; 65: 1715-1720
23. Mojcik CF, Levy JH. Aprotinin and the systemic inflammatory response after cardiopulmonary bypass. Ann Thorac Surg. 2001 ; 71: 745-754 (Pubitemid 32173882)
24. Hsia TY, McQuinn TC, Mukherjee R, et al. Effects of aprotinin or tranexamic acid on proteolytic/cytokine profiles in infants after cardiac surgery. Ann Thorac Surg. 89: 1843-1852
25. Havel M, Teufelsbauer H, Knobl P, et al. Effect of intraoperative aprotinin administration on postoperative bleeding in patients undergoing cardiopulmonary bypass operation. J Thorac Cardiovasc Surg. 1991 ; 101: 968-972