Basic surgical techniques in the göttingen minipig: Intubation, bladder catheterization, femoral vessel catheterization, and transcardial perfusion

Journal of Visualized Experiments

Volumn , Issue 52, 2011, Pages

  Ettrup, Kaare S ^a,b   Glud, Andreas N ^b   Orlowski, Dariusz ^b   Fitting, Lise M ^a   Meier, Kaare ^a   Soerensen, Jens Christian ^a   Bjarkam, Carsten R ^a,b   Olsen Alstrup, Aage K ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 80055118676     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/2652     Document Type: Article

References (14)

1. Lind, N.M., Moustgaard, A., Jelsing, J., Vajta, G., Cumming, P., Hansen, A.K. The use of pigs in neuroscience: modeling brain disorders. Neurosci Biobehav Rev 31 (5): 728-751 (2007).
2. Ettrup, K.S., Sorensen, J.C., Bjarkam, C.R. The anatomy of the Gottingen minipig hypothalamus. J Chem Neuroanat 39 (3): 151-165 (2010).
3. Larsen, M.O., Rolin, B., Sturis, J., et al. Measurements of insulin responses as predictive markers of pancreatic beta-cell mass in normal and beta-cell-reduced lean and obese Gottingen minipigs in vivo. Am J Physiol Endocrinol Metab 290 (4): E670-E677 (2006).
4. Forster, R., Ancian, P., Fredholm, M., Simianer, H., Whitelaw, B. The minipig as a platform for new technologies in toxicology. J Pharmacol Toxicol Methods (2010).
5. Popov, A.F., Dorge, H., Hinz, J. et al. Accelerated intimal hyperplasia in aortocoronary internal mammary vein grafts in minipigs. J Cardiothorac Surg 3: 20 (2008).
6. Swindle, M.M. Swine in the Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques. second ed. ed. CRC Press (2007).
7. Bjarkam, C.R., Cancian, G., Glud, A.N., Ettrup, K.S., Jorgensen, R.L., Sorensen, J.C. MRI-guided stereotaxic targeting in pigs based on a stereotaxic localizer box fitted with an isocentric frame and use of SurgiPlan computer-planning software. J Neurosci Methods 183 (2): 119-126 (2009).
8. Val-Laillet, D., Blat, S., Louveau, I., Malbert, C.H. A computed tomography scan application to evaluate adiposity in a minipig model of human obesity. Br J Nutr 1-10 (2010).
9. Larsen, M., Bjarkam, C.R., Stoltenberg, M., Sorensen, J.C., Danscher, G. An autometallographic technique for myelin staining in formaldehyde-fixed tissue. Histol Histopathol 18 (4): 1125-1130 (2003).
10. Alstrup, A.K.O. Anaesthesia and Analgesia in Ellegaard Göttingen minipigs. Jannerup. DK (2010).
11. Jensen, K.N., Deding, D., Sorensen, J.C., Bjarkam, C.R. Long-term implantation of deep brain stimulation electrodes in the pontine micturition centre of the Gottingen minipig. Acta Neurochir (Wien) 151 (7): 785-794 (2009).
12. Cumming, P., Moller, M., Benda, K., et al. A PET study of effects of chronic 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) on serotonin markers in Gottingen minipig brain. Synapse 61 (7): 478-487 (2007).
13. Olsen, A.K., Keiding, S., Munk, O.L. Effect of hypercapnia on cerebral blood flow and blood volume in pigs studied by positron emission tomography. Comp Med 56 (5): 416-420 (2006).
14. Jonkers, B.W., Sterk, J.C., Wouterlood, F.G. Transcardial perfusion fixation of the CNS by means of a compressed-air-driven device. J Neurosci Methods 12 (2): 141-149 (1984).