Possibility of myelodysplastic syndromes screening using a complete blood automated cell count

Leukemia Research

Volumn 35, Issue 12, 2011, Pages 1623-1627

  Rocco, Vincenzo ^a   Maconi, Mariacaterina ^b   Gioia, Maria ^a   Silvestri, Maria Grazia ^c   Tanca, Donatella ^d   Catalano, Teodora ^a   Avino, Daniela ^e   Di Palma, Anna ^e   Rovetti, Adele ^e   Danise, Paolo ^e  

^a AO Rummo ^*  (Italy)

^b ASL Alessandria   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d ASL 4 Chiaverese   (Italy)

^e ASL Salerno 1   (Italy)

Author keywords

Automated hematology analyser; Complete blood cell count; Cytopenia; Myelodysplastic syndromes; Sensitivity; Specificity

Indexed keywords

ADULT; AGED; ANISOCYTOSIS; ARTICLE; AUTOMATION; BLOOD CELL COUNT; CONTROLLED STUDY; DYSERYTHROPOIESIS; DYSPLASIA; ERYTHROCYTE; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; FEMALE; GRANULOCYTE; HUMAN; LEUKOCYTE DISORDER; MAJOR CLINICAL STUDY; MALE; MONOCYTOSIS; MYELODYSPLASTIC SYNDROME; NEUTROPHIL; PRIORITY JOURNAL; RETICULOCYTE; SCREENING TEST; SENSITIVITY AND SPECIFICITY; THROMBOCYTOPENIA;

ADULT; AGED; AGED, 80 AND OVER; AUTOMATION, LABORATORY; BLOOD CELL COUNT; EARLY DETECTION OF CANCER; FEASIBILITY STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; MYELODYSPLASTIC SYNDROMES; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY;

EID: 80055112333     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2011.06.015     Document Type: Article

References (24)

1. Swerdlow S.H., Campo E., Harris N.L., Jaffe E.S., Pileri S.A., Stein H-, et al. WHO classification of tumours of haematopoietic and lymphoid tissue 2008.
2. Cazzola M., Malcovati L. Myelodysplastic syndromes - coping with ineffective hematopoiesis. NEJM 2005, 352(6):536-538.
3. Hellström-Lindberg E. Myelodysplastic syndromes: an historical perspective. Hematology 2008:42.
4. Malcovati L., Cazzola M. Myelodisplastic/myeloproliferative disorders. Haematologica 2008, 93(1).
5. Nimer S.D. Myelodysplastic syndromes. Blood 2008, 111:4841-4851.
6. Nimer S.D. MDS: a stem cell disorder - but what exactly is wrong the primitive hematopoietic cells in this diseases?. Hematology 2008, 43-51.
7. Orazi A., Germing U. The myelodysplastic/myeloproliferative neoplasms: myeloproliferative diseases with dysplastic features. Leukemia 2008, 22:1308-1319.
8. Rollison D.E., Howlader N., Smith M.T., et al. Epidemiology of myelodysplastic syndromes and chronic myeloproliferative disorders in the United States, 2001-2004, using data from the NAACCR and SEER programs. Blood 2008, 112:45-52.
9. Tettamanti M., Lucca U., Gandini F., et al. Prevalence Incidence and types of mild anemia in the elderly: the "Health and anemia" population-base study. Haematologica 2010, 95.(11).
10. Carmel R. Anemia and aging: an overview of clinical, diagnostic and biological issues. Blood Rev 2001, 15(1):9-13.
11. Codispoti K.E.T., Deplama L. Myelodysplastic syndromes in elderly patients: correlation of CBC with cytogenetic and FISH analysis. Int J Lab Hematol 2009, 1-6.
12. Vardiman W. Hematopathological concepts and controversies in the diagnosis and classification of myelodysplastic syndromes. Hematology 2006, 199-204.
13. Cantù Rajnoldi A., Fenu S., Kerndrup G., et al. Evaluation of dysplastic features in myelodysplastic syndromes: experience from the morphology group of European Working Group of MDS in Childhood (EWOG-MDS). Ann Hematol 2005, 84:429-433.
14. Morfologia del sangue. G. D'Onofrio, G. Zini. Roma: Verduci Editore; 1997.
15. Hoffmann J.J.M. How useful are haematology analyser flags?. CCLM 2004, 42(4):357-358.
16. Gulley M.L., Bentley S.A., Ross D.W. Neutrophil myeloperoxidase measurement uncovers masked megaloblastic anemia. Blood 1990, 76:1004-1007. [see comments].
17. Lanza F. Clinical manifestation of myeloperoxidase deficiency. J Mol Med 1998, 76:676-681.
18. Furundarena R., Araiz M., Uranga M-, et al. The utility of the Sysmex XE-2100 analyzer's NEUT-X and NEUT-Y parameters for detecting neutrophil dysplasia in myelodysplastic syndromes. J Int J Lab Hematol 2010, 1-10.
19. Haschke-Becker E., Vockenhuber M., Niedetzky P., et al. A new high-throughput screening method for detection of CLL and MDS. CCLM 2008, 46(1):85-88.
20. Ljiung T. Hypochromic red blood cells in low-risk myelodysplastic syndromes: effect of treatment with hemopoietic growth factors. Haematologica 2004, 89:1446-1453.
21. Murphy P.T., Quinn J.P., O'Donghaile D., et al. Myelodysplastic patients with raised percentage of hypochromic red cells have evidence of functional iron deficiency. Ann Hematol 2006, 85:455-457.
22. Rovò A. Sideroblastic changes of the bone marrow can be predicted by the erythrogram of peripheral blood. Int J Lab Hematol 2010, 1-7.
23. Harris N. Performance evaluation of the ADVIA 2120 hematology analyzer: an international multicenter clinical trial. Lab Haematol 2005, 11:62-70.
24. Bonomi A., Lanza F., Dabusti M., et al. Increased myeloproxidase index and large unstained cell values can predict the neutropenia fase of cancer patients treated with standard dose chemotherapy. Cytometry 2001, 46:92-97.