Genome-wide analysis of aminoacylation (charging) levels of tRNA using microarrays

Journal of Visualized Experiments

Volumn , Issue 40, 2010, Pages

  Zaborske, John ^a   Pan, Tao ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 80055110543     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/2007     Document Type: Article

References (8)

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2. Wek, S.A., S. Zhu, and R.C. Wek, The histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids. p. 4497-4506 (1995).
3. Hinnebusch, A.G., Translational Regulation of GCN4 and the General Amino Acid Control of Yeast. Annual Review of Microbiology, 59(1): p. 407-450 (2005).
4. Braeken, K., et al., New horizons for (p)ppGpp in bacterial and plant physiology. Trends in Microbiology, 14(1): p. 45-54 (2006).
5. Dong, J., et al., Uncharged tRNA Activates GCN2 by Displacing the Protein Kinase Moiety from a Bipartite tRNA-Binding Domain. Molecular Cell, 6(2): p. 269-279 (2000).
6. Cashel M., et al., The Stringent Response, in Escherichia coli and Salmonella: cellular and molecular biology, N. F.C., Editor, ASM Press: Washington D.C/. p. 1458-1496 (1996).
7. Dittmar, K.A., et al., Selective charging of tRNA isoacceptors induced by amino-acid starvation. EMBO Rep, 6(2): p. 151-7 (2005).
8. Zhou, Y., et al., High levels of tRNA abundance and alteration of tRNA charging by bortezomib in multiple myeloma. Biochem Biophys Res Commun, 385(2): p. 160-4 (2009).