-
1
-
-
77649254869
-
Resistance profile of etravirine: Combined analysis of baseline genotypic and phenotypic data from the DUET studies
-
Vingerhoets J, Tambuyzer L, Azijn H, et al. Resistance profile of etravirine: combined analysis of baseline genotypic and phenotypic data from the DUET studies. AIDS. 2010;24:503-514.
-
(2010)
AIDS
, vol.24
, pp. 503-514
-
-
Vingerhoets, J.1
Tambuyzer, L.2
Azijn, H.3
-
2
-
-
78649305180
-
Characterization of genotypic and phenotypic changes in HIV-1-infected patients with virologic failure on an etravirine-containing regimen in the DUET-1 and DUET-2 clinical studies
-
Tambuyzer L, Vingerhoets J, Azijn H, et al. Characterization of genotypic and phenotypic changes in HIV-1-infected patients with virologic failure on an etravirine-containing regimen in the DUET-1 and DUET-2 clinical studies. AIDS Res Hum Retroviruses. 2010;26:1197-1205.
-
(2010)
AIDS Res Hum Retroviruses
, vol.26
, pp. 1197-1205
-
-
Tambuyzer, L.1
Vingerhoets, J.2
Azijn, H.3
-
3
-
-
0026693137
-
Crystal structure at 3.5 A° resolution of HIV-1 reverse transcriptase complexed with an inhibitor
-
Kohlstaedt LA, Wang J, Friedman JM, et al. Crystal structure at 3.5 A° resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Science. 1992;256:1783-1790.
-
(1992)
Science
, vol.256
, pp. 1783-1790
-
-
Kohlstaedt, L.A.1
Wang, J.2
Friedman, J.M.3
-
4
-
-
73549115378
-
Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: A review of the last 20 years (1989-2009)
-
de Bethune MP. Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: a review of the last 20 years (1989-2009). Antiviral Res. 2010;85:75-90.
-
(2010)
Antiviral Res
, vol.85
, pp. 75-90
-
-
De Bethune, M.P.1
-
5
-
-
0344474694
-
A rapid method for simultaneous detection of phenotypic resistance to inhibitors of protease and reverse transcriptase in recombinant human immunodeficiency virus type 1 isolates from patients treated with antiretroviral drugs
-
Hertogs K, de Béthune MP, Miller V, et al. A rapid method for simultaneous detection of phenotypic resistance to inhibitors of protease and reverse transcriptase in recombinant human immunodeficiency virus type 1 isolates from patients treated with antiretroviral drugs. Antimicrob Agents Chemother. 1998;42:269-276. (Pubitemid 28114430)
-
(1998)
Antimicrobial Agents and Chemotherapy
, vol.42
, Issue.2
, pp. 269-276
-
-
Hertogs, K.1
De Bethune, M.-P.2
Miller, V.3
Ivens, T.4
Schel, P.5
Van Cauwenberge, A.6
Van Den Eynde, C.7
Van Gerwen, V.8
Azijn, H.9
Van Houtte, M.10
Peeters, F.11
Staszewski, S.12
Conant, M.13
Bloor, S.14
Kemp, S.15
Larder, B.16
Pauwels, R.17
-
6
-
-
0003327566
-
Comprehensive HIV drug resistance monitoring using rapid, high-throughput phenotypic and genotypic assays with correlative data analysis
-
Lake Maggiore, Italy. Abstract 51
-
Pauwels R, Hertogs K, Kemp S, et al. Comprehensive HIV drug resistance monitoring using rapid, high-throughput phenotypic and genotypic assays with correlative data analysis. Presented at the 2nd International Workshop HIV Drug Resistance; 1998; Lake Maggiore, Italy. Abstract 51.
-
(1998)
The 2nd International Workshop HIV Drug Resistance
-
-
Pauwels, R.1
Hertogs, K.2
Kemp, S.3
-
7
-
-
75749118495
-
TMC278, a next-generation NNRTI, active against wild-type and NNRTI-resistant HIV-1
-
Azijn H, Tirry I, Vingerhoets J, et al. TMC278, a next-generation NNRTI, active against wild-type and NNRTI-resistant HIV-1. Antimicrob Agents Chemother. 2010;54:718-727.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 718-727
-
-
Azijn, H.1
Tirry, I.2
Vingerhoets, J.3
-
8
-
-
78649971571
-
Efficacy and safety of etravirine at Week 96 in treatment-experienced HIV-1-infected patients in the DUET-1 and DUET-2 trials
-
Katlama C, Clotet B, Mills A, et al. Efficacy and safety of etravirine at Week 96 in treatment-experienced HIV-1-infected patients in the DUET-1 and DUET-2 trials. Antivir Ther. 2010;15:1045-1052.
-
(2010)
Antivir Ther
, vol.15
, pp. 1045-1052
-
-
Katlama, C.1
Clotet, B.2
Mills, A.3
-
9
-
-
61849143798
-
Compilation and prevalence of mutations associated with resistance to non-nucleoside reverse transcriptase inhibitors
-
Tambuyzer L, Azijn H, Rimsky LT, et al. Compilation and prevalence of mutations associated with resistance to non-nucleoside reverse transcriptase inhibitors. Antivir Ther. 2009;14:103-109.
-
(2009)
Antivir Ther
, vol.14
, pp. 103-109
-
-
Tambuyzer, L.1
Azijn, H.2
Rimsky, L.T.3
-
10
-
-
0035261907
-
Site-directed mutagenesis of human immunodeficiency virus type 1 reverse transcriptase at amino acid position 138
-
DOI 10.1006/viro.2000.0742
-
Pelemans H, Aertsen A, Van Laethem K, et al. Site-directed mutagenesis of human immunodeficiency virus type 1 reverse transcriptase at amino acid position 138. Virology. 2001;280:97-106. (Pubitemid 34162519)
-
(2001)
Virology
, vol.280
, Issue.1
, pp. 97-106
-
-
Pelemans, H.1
Aertsen, A.2
Van Laethem, K.3
Vandamme, A.-M.4
De Clercq, E.5
Perez-Perez, M.J.6
San-Felix, A.7
Velazquez, S.8
Camarasa, M.-J.9
Balzarini, J.10
-
11
-
-
0028099251
-
Resistance of HIV-1 reverse transcriptase against [2', 5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5"-(4"-amino-1", 2"-oxathiole-2", 2"-dioxide)] (TSAO) derivatives is determined by the mutation Glu138->Lys on the p51 subunit
-
Jonckheere H, Taymans JM, Balzarini J, et al. Resistance of HIV-1 reverse transcriptase against [2', 5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5"- (4"-amino-1", 2"-oxathiole-2", 2"-dioxide)] (TSAO) derivatives is determined by the mutation Glu138->Lys on the p51 subunit. J Biol Chem. 1994;269:25255-25258.
-
(1994)
J Biol Chem
, vol.269
, pp. 25255-25258
-
-
Jonckheere, H.1
Taymans, J.M.2
Balzarini, J.3
-
12
-
-
0027202617
-
Human immunodeficiency virus type 1 (HIV-1) strains selected for resistance against the HIV-1-specific [2',5'-bis-O-(tert- butyldimethylsilyl)- 3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''- dioxide)]-β-D- pentofuranosyl (TSAO) nucleoside analogues retain sensitivity to HIV-1-specific nonnucleoside inhibitors
-
Balzarini J, Karlsson A, Vandamme A-M, et al. Human immunodeficiency virus type 1 (HIV-1) strains selected for resistance against the HIV-1-specific [2', 5'-bis-O-(tertbutyldimethylsilyl)-3'-spiro-5"-(4"-amino-1", 2"-oxathiole-2", 2"-dioxide)]-f8-D-pentofuranosyl (TSAO) nucleoside analogues retain sensitivity to HIV-1-specific nonnucleoside inhibitors. Proc Natl Acad Sci U S A. 1993;90:6952-6956. (Pubitemid 23222366)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.15
, pp. 6952-6956
-
-
Balzarini, J.1
Karlsson, A.2
Vandamme, A.-M.3
Perez-Perez, M.-J.4
Zhang, H.5
Vrang, L.6
Oberg, B.7
Backbro, K.8
Unge, T.9
San-Felix, A.10
Velazquez, S.11
Camarasa, M.-J.12
De Clercq, E.13
-
13
-
-
0027214433
-
Treatment of human immunodeficiency virus type 1 (HIV-1)-infected cells with combinations of HIV-1-specific inhibitors results in a different resistance pattern than does treatment with single-drug therapy
-
Balzarini J, Karlsson A, Pérez-Pérez MJ, et al. Treatment of human immunodeficiency virus type 1 (HIV-1)-infected cells with combinations of HIV-1-specific inhibitors results in a different resistance pattern than does treatment with single-drug therapy. J Virol. 1993;67:5353-5359. (Pubitemid 23241368)
-
(1993)
Journal of Virology
, vol.67
, Issue.9
, pp. 5353-5359
-
-
Balzarini, J.1
Karlsson, A.2
Perez-Perez, M.-J.3
Camarasa, M.-J.4
Tarpley, W.G.5
De Clercq, E.6
-
15
-
-
0033169086
-
Suppression of resistance to drugs targeted to human immunodeficiency virus reverse transcriptase by combination therapy
-
Balzarini J. Suppression of resistance to drugs targeted to human immunodeficiency virus reverse transcriptase by combination therapy. Biochem Pharmacol. 1999;58:1-27.
-
(1999)
Biochem Pharmacol
, vol.58
, pp. 1-27
-
-
Balzarini, J.1
-
16
-
-
78751693611
-
Characterization of the E138K resistance mutation in HIV-1 reverse transcriptase conferring susceptibility to etravirine in B and non-B HiV-1 subtypes
-
Asahchop E, Oliveira M, Wainberg M, et al. Characterization of the E138K resistance mutation in HIV-1 reverse transcriptase conferring susceptibility to etravirine in B and non-B HiV-1 subtypes. Antimicrob Agents Chemother. 2011;55:600-607
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 600-607
-
-
Asahchop, E.1
Oliveira, M.2
Wainberg, M.3
-
17
-
-
67149115786
-
In vitro cross-resistance profile for a next-generation NNRTI: IDX899
-
Jakubik JJ, Chapron C, Hubbard L, et al. In vitro cross-resistance profile for a next-generation NNRTI: IDX899. Antiviral Ther. 2008;13(suppl 3):A28.
-
(2008)
Antiviral Ther
, vol.13
, Issue.3 SUPPL.
-
-
Jakubik, J.J.1
Chapron, C.2
Hubbard, L.3
-
18
-
-
79960361710
-
Characterization of the resistance profile of TMC278:48-week analysis of the Phase III studies ECHO and THRIVE
-
Boston, MA. Abstract H-1810
-
Rimsky L, Eron J, Clotet B, et al. Characterization of the resistance profile of TMC278:48-week analysis of the Phase III studies ECHO and THRIVE. Presented at the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2010; Boston, MA. Abstract H-1810.
-
(2010)
The 50th Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Rimsky, L.1
Eron, J.2
Clotet, B.3
-
19
-
-
68649098791
-
Additional HIV-1 mutation patterns associated with reduced phenotypic susceptibility to etravirine in clinical samples
-
Kagan RM, Sista P, Pattery T, et al. Additional HIV-1 mutation patterns associated with reduced phenotypic susceptibility to etravirine in clinical samples. AIDS. 2009;23:1602-1605.
-
(2009)
AIDS
, vol.23
, pp. 1602-1605
-
-
Kagan, R.M.1
Sista, P.2
Pattery, T.3
-
20
-
-
67149133997
-
Development of virco (r) type HIV-1 resistance analysis, including clinical cutoffs for TMC125 (etravirine, ETR), a new NNRTI
-
Boston, MA. Abstract 873
-
Winters B, Villacian J, Van Craenenbroeck E, et al. Development of virco (r) type HIV-1 resistance analysis, including clinical cutoffs for TMC125 (etravirine, ETR), a new NNRTI. Presented at the 15th Conference on Retroviruses and Opportunistic Infections; 2008; Boston, MA. Abstract 873.
-
(2008)
The 15th Conference on Retroviruses and Opportunistic Infections
-
-
Winters, B.1
Villacian, J.2
Van Craenenbroeck, E.3
-
21
-
-
82455164684
-
Improved genotypic algorithm for predicting etravirine susceptibility: Comprehensive list of mutations identified through correlation with matched phenotype
-
San Francisco, CA. Abstract 574
-
Haddad M, Stawiski E, Benhamida J, et al. Improved genotypic algorithm for predicting etravirine susceptibility: comprehensive list of mutations identified through correlation with matched phenotype. Presented at the 17th Conference on Retroviruses and Opportunistic Infections; 2010; San Francisco, CA. Abstract 574.
-
(2010)
The 17th Conference on Retroviruses and Opportunistic Infections
-
-
Haddad, M.1
Stawiski, E.2
Benhamida, J.3
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