-
1
-
-
0025942636
-
Haemophilia in the 1990s: report of a joint meeting of the World Health Organization and World Federation of Hemophilia
-
Kasper CK, Mannucci PM, Bulyzhenkov V, Brettler DB, Chuansumrit A, Heijnen L, Isarankura P, Kernoff PB, Peake I, Rickard KA, Schulman S, Smit Sibinga CT. Haemophilia in the 1990s: report of a joint meeting of the World Health Organization and World Federation of Hemophilia. Vox Sang 1991; 61: 221-4.
-
(1991)
Vox Sang
, vol.61
, pp. 221-224
-
-
Kasper, C.K.1
Mannucci, P.M.2
Bulyzhenkov, V.3
Brettler, D.B.4
Chuansumrit, A.5
Heijnen, L.6
Isarankura, P.7
Kernoff, P.B.8
Peake, I.9
Rickard, K.A.10
Schulman, S.11
Smit Sibinga, C.T.12
-
2
-
-
0025017341
-
The increasing prevalence of haemophilia
-
Rosendaal FR, Briet E. The increasing prevalence of haemophilia. Thromb Haemost 1990; 63: 145.
-
(1990)
Thromb Haemost
, vol.63
, pp. 145
-
-
Rosendaal, F.R.1
Briet, E.2
-
3
-
-
0028078717
-
Hemophilia A
-
Hoyer LW. Hemophilia A. N Engl J Med 1994; 330: 38-47.
-
(1994)
N Engl J Med
, vol.330
, pp. 38-47
-
-
Hoyer, L.W.1
-
4
-
-
0021715168
-
Expression of active human factor VIII from recombinant DNA clones
-
Wood WI, Capon DJ, Simonsen CC, Eaton DL, Gitschier J, Keyt B, Seeburg PH, Smith DH, Hollingshead P, Wion KL, Delwart E, Tuddenham EGD, Vehar GA, Lawn RM. Expression of active human factor VIII from recombinant DNA clones. Nature (London) 1984; 312: 330-7.
-
(1984)
Nature (London)
, vol.312
, pp. 330-337
-
-
Wood, W.I.1
Capon, D.J.2
Simonsen, C.C.3
Eaton, D.L.4
Gitschier, J.5
Keyt, B.6
Seeburg, P.H.7
Smith, D.H.8
Hollingshead, P.9
Wion, K.L.10
Delwart, E.11
Tuddenham, E.G.D.12
Vehar, G.A.13
Lawn, R.M.14
-
5
-
-
0021677942
-
Structure of human factor VIII
-
Vehar GA, Keyt B, Eaton D, Rodriguez H, O'Brien DP, Rotblat F, Oppermann H, Keck R, Wood WI, Harkins RN, Tuddenham EGD, Lawn RM, Capon DJ. Structure of human factor VIII. Nature (London) 1984; 312: 337-42.
-
(1984)
Nature (London)
, vol.312
, pp. 337-342
-
-
Vehar, G.A.1
Keyt, B.2
Eaton, D.3
Rodriguez, H.4
O'Brien, D.P.5
Rotblat, F.6
Oppermann, H.7
Keck, R.8
Wood, W.I.9
Harkins, R.N.10
Tuddenham, E.G.D.11
Lawn, R.M.12
Capon, D.J.13
-
6
-
-
0021715169
-
Molecular cloning of a cDNA encoding human antihemophilic factor
-
Toole JJ, Knopf JL, Wozney JM, Sultzman LA, Buecker JL, Pittman DD, Kaufman RJ, Brown E, Shoemaker C, Orr EC, Amphlett GW, Foster WB, Coe ML, Knutson GJ, Fass DN, Hewick RM. Molecular cloning of a cDNA encoding human antihemophilic factor. Nature (London) 1984; 312: 342-7.
-
(1984)
Nature (London)
, vol.312
, pp. 342-347
-
-
Toole, J.J.1
Knopf, J.L.2
Wozney, J.M.3
Sultzman, L.A.4
Buecker, J.L.5
Pittman, D.D.6
Kaufman, R.J.7
Brown, E.8
Shoemaker, C.9
Orr, E.C.10
Amphlett, G.W.11
Foster, W.B.12
Coe, M.L.13
Knutson, G.J.14
Fass, D.N.15
Hewick, R.M.16
-
7
-
-
33845754008
-
Defining 'full-length' recombinant factor VIII: a comparative structural analysis
-
Jankowski MA, Patel H, Rouse JC, Marzilli LA, Weston SB, Sharpe PJ. Defining 'full-length' recombinant factor VIII: a comparative structural analysis. Haemophilia 2007; 13: 30-7.
-
(2007)
Haemophilia
, vol.13
, pp. 30-37
-
-
Jankowski, M.A.1
Patel, H.2
Rouse, J.C.3
Marzilli, L.A.4
Weston, S.B.5
Sharpe, P.J.6
-
8
-
-
44349150005
-
Progress in the molecular biology of inherited bleeding disorders
-
Pipe SW, High KA, Ohashi K, Ural AU, Lillicrap D. Progress in the molecular biology of inherited bleeding disorders. Haemophilia 2008; 14(Suppl. 3): 130-7.
-
(2008)
Haemophilia
, vol.14
, Issue.SUPPL.. 3
, pp. 130-137
-
-
Pipe, S.W.1
High, K.A.2
Ohashi, K.3
Ural, A.U.4
Lillicrap, D.5
-
9
-
-
11044224626
-
New high-technology products for the treatment of haemophilia
-
Pipe SW, Saint-Remy J-M, Walsh CE. New high-technology products for the treatment of haemophilia. Haemophilia 2004; 10: 55-63.
-
(2004)
Haemophilia
, vol.10
, pp. 55-63
-
-
Pipe, S.W.1
Saint-Remy, J.-M.2
Walsh, C.E.3
-
10
-
-
0027237331
-
Sequences in the coding region of clotting factor VIII act as dominant inhibitors of RNA accumulation and protein production
-
Lynch CM, Israel DI, Kaufman RJ, Miller AD. Sequences in the coding region of clotting factor VIII act as dominant inhibitors of RNA accumulation and protein production. Hum Gene Ther 1993; 4: 259-72.
-
(1993)
Hum Gene Ther
, vol.4
, pp. 259-272
-
-
Lynch, C.M.1
Israel, D.I.2
Kaufman, R.J.3
Miller, A.D.4
-
11
-
-
0029098922
-
Sequences within the coding regions of clotting factor VIII and CFTR block transcriptional elongation
-
Koeberl DD, Halbert CL, Krumm A, Miller AD. Sequences within the coding regions of clotting factor VIII and CFTR block transcriptional elongation. Hum Gene Ther 1995; 6: 469-79.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 469-479
-
-
Koeberl, D.D.1
Halbert, C.L.2
Krumm, A.3
Miller, A.D.4
-
12
-
-
0028917478
-
Expression of the blood-clotting factor-VIII cDNA is repressed by a transcriptional silencer located in its coding region
-
Hoeben RC, Fallaux FJ, Cramer SJ, van den Wollenberg DJM, van Ormondt H, Brieet E, van der Eb AJ. Expression of the blood-clotting factor-VIII cDNA is repressed by a transcriptional silencer located in its coding region. Blood 1995; 85: 2447-54.
-
(1995)
Blood
, vol.85
, pp. 2447-2454
-
-
Hoeben, R.C.1
Fallaux, F.J.2
Cramer, S.J.3
van den Wollenberg, D.J.M.4
van Ormondt, H.5
Brieet, E.6
van der Eb, A.J.7
-
13
-
-
0023918719
-
Synthesis, processing, and secretion of recombinant human factor VIII expressed in mammalian cells
-
Kaufman RJ, Wasley LC, Dorner AJ. Synthesis, processing, and secretion of recombinant human factor VIII expressed in mammalian cells. J Biol Chem 1988; 263: 6352-62.
-
(1988)
J Biol Chem
, vol.263
, pp. 6352-6362
-
-
Kaufman, R.J.1
Wasley, L.C.2
Dorner, A.J.3
-
14
-
-
1942521325
-
Bioengineering of coagulation factor VIII for improved secretion
-
Miao HZ, Sirachainan N, Palmer L, Kucab P, Cunningham MA, Kaufman RJ, Pipe SW. Bioengineering of coagulation factor VIII for improved secretion. Blood 2004; 103: 3412-19.
-
(2004)
Blood
, vol.103
, pp. 3412-3419
-
-
Miao, H.Z.1
Sirachainan, N.2
Palmer, L.3
Kucab, P.4
Cunningham, M.A.5
Kaufman, R.J.6
Pipe, S.W.7
-
15
-
-
0026565453
-
A2 domain of human recombinant-derived factor VIII is required for procoagulant activity but not for thrombin cleavage
-
Pittman DD, Millenson M, Marquette K, Bauer K, Kaufman RJ. A2 domain of human recombinant-derived factor VIII is required for procoagulant activity but not for thrombin cleavage. Blood 1992; 79: 389-97.
-
(1992)
Blood
, vol.79
, pp. 389-397
-
-
Pittman, D.D.1
Millenson, M.2
Marquette, K.3
Bauer, K.4
Kaufman, R.J.5
-
16
-
-
0024597022
-
Effect of von Willebrand factor coexpression on the synthesis and secretion of factor VIII in Chinese hamster ovary cells
-
Kaufman RJ, Wasley LC, Davies MV, Wise RJ, Israel DI, Dorner AJ. Effect of von Willebrand factor coexpression on the synthesis and secretion of factor VIII in Chinese hamster ovary cells. Mol Cell Biol 1989; 9: 1233-42.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 1233-1242
-
-
Kaufman, R.J.1
Wasley, L.C.2
Davies, M.V.3
Wise, R.J.4
Israel, D.I.5
Dorner, A.J.6
-
17
-
-
0035988814
-
Temporal and spatial expression of biologically active human factor VIII in the milk of transgenic mice driven by mammary-specific bovine lactalbumin regulation sequences
-
Chen C-M, Wang C-H, Wu S-C, Lin C-C, Lin S-H, Cheng WTK. Temporal and spatial expression of biologically active human factor VIII in the milk of transgenic mice driven by mammary-specific bovine lactalbumin regulation sequences. Transgenic Res 2002; 11: 257-68.
-
(2002)
Transgenic Res
, vol.11
, pp. 257-268
-
-
Chen, C.-M.1
Wang, C.-H.2
Wu, S.-C.3
Lin, C.-C.4
Lin, S.-H.5
Cheng, W.T.K.6
-
18
-
-
23744477288
-
Increased transgene integration efficiency upon microinjection of DNA into both pronuclei of rabbit embryos
-
Chrenek P, Vasicek D, Makarevich AV, Jurcik R, Suvegova K, Parkanyi V, Bauer M, Rafay J, Batorova A, Paleyanda RK. Increased transgene integration efficiency upon microinjection of DNA into both pronuclei of rabbit embryos. Transgenic Res 2005; 14: 417-28.
-
(2005)
Transgenic Res
, vol.14
, pp. 417-428
-
-
Chrenek, P.1
Vasicek, D.2
Makarevich, A.V.3
Jurcik, R.4
Suvegova, K.5
Parkanyi, V.6
Bauer, M.7
Rafay, J.8
Batorova, A.9
Paleyanda, R.K.10
-
19
-
-
34247334120
-
Expression of recombinant human factor viii in milk of several generations of transgenic rabbits
-
Cherenek P, Ryban L, Vetr H, Makarevich AV, Uhrin P, Paleyanda RK, Binder BR. Expression of recombinant human factor viii in milk of several generations of transgenic rabbits. Transgenic Res 2007; 16: 353-61.
-
(2007)
Transgenic Res
, vol.16
, pp. 353-361
-
-
Cherenek, P.1
Ryban, L.2
Vetr, H.3
Makarevich, A.V.4
Uhrin, P.5
Paleyanda, R.K.6
Binder, B.R.7
-
20
-
-
0033150573
-
Expression of human blood clotting factor VIII in the mammary gland of transgenic sheep
-
Niemann H, Halter R, Carnwath JW, Hermann D, Lemme E, Paul D. Expression of human blood clotting factor VIII in the mammary gland of transgenic sheep. Transgenic Res 1999; 8: 237-47.
-
(1999)
Transgenic Res
, vol.8
, pp. 237-247
-
-
Niemann, H.1
Halter, R.2
Carnwath, J.W.3
Hermann, D.4
Lemme, E.5
Paul, D.6
-
21
-
-
0030771837
-
Transgenic pig produce functional human factor VIII in milk
-
Paleyanda RK, Velander WH, Lee TK, Scandella DH, Gwazdauskas FC, Knight JW, Drohan WN, Lubon H. Transgenic pig produce functional human factor VIII in milk. Nat Biotechnol 1997; 15: 971-5.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 971-975
-
-
Paleyanda, R.K.1
Velander, W.H.2
Lee, T.K.3
Scandella, D.H.4
Gwazdauskas, F.C.5
Knight, J.W.6
Drohan, W.N.7
Lubon, H.8
-
22
-
-
0033128687
-
Bovine follicular dynamics, oocyte recovery, and development of oocytes microinjected with a green fluorescent protein construct
-
Chauhan MS, Nadir S, Bailey TL, Pryor AW, Butler SP, Notter DR, Velander WH, Gwazdauskas FC. Bovine follicular dynamics, oocyte recovery, and development of oocytes microinjected with a green fluorescent protein construct. J Dairy Sci 1999; 82: 918-26.
-
(1999)
J Dairy Sci
, vol.82
, pp. 918-926
-
-
Chauhan, M.S.1
Nadir, S.2
Bailey, T.L.3
Pryor, A.W.4
Butler, S.P.5
Notter, D.R.6
Velander, W.H.7
Gwazdauskas, F.C.8
-
23
-
-
0025285392
-
High-level expression of biologically active human alpha 1-antitrypsin in the milk of transgenic mice
-
Archibald AL, McClenaghan M, Hornsey V, Simons JP, Clark AJ. High-level expression of biologically active human alpha 1-antitrypsin in the milk of transgenic mice. Proc Natl Acad Sci USA 1990; 87: 5178-82.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 5178-5182
-
-
Archibald, A.L.1
McClenaghan, M.2
Hornsey, V.3
Simons, J.P.4
Clark, A.J.5
-
24
-
-
0026693703
-
Production of biologically active human protein C in the milk of transgenic mice
-
Velander WH, Page RL, Morcol T, Russell CG, Canseco R, Young JM, Drohan WN, Gwazdauskas FC, Wilkins TD, Johnson JL. Production of biologically active human protein C in the milk of transgenic mice. Ann N Y Acad Sci 1992; 665: 391-403.
-
(1992)
Ann N Y Acad Sci
, vol.665
, pp. 391-403
-
-
Velander, W.H.1
Page, R.L.2
Morcol, T.3
Russell, C.G.4
Canseco, R.5
Young, J.M.6
Drohan, W.N.7
Gwazdauskas, F.C.8
Wilkins, T.D.9
Johnson, J.L.10
-
25
-
-
0028058606
-
Identification of individual tyrosine sulfation sites within factor VIII required for optimal activity and efficient thrombin cleavage
-
Michnick DA, Pittman DD, Wise RJ, Kaufman RJ. Identification of individual tyrosine sulfation sites within factor VIII required for optimal activity and efficient thrombin cleavage. J Biol Chem 1994; 269: 20095-102.
-
(1994)
J Biol Chem
, vol.269
, pp. 20095-20102
-
-
Michnick, D.A.1
Pittman, D.D.2
Wise, R.J.3
Kaufman, R.J.4
-
27
-
-
0032528496
-
Mechanism and kinetics of factor viii inactivation: study with an igg4 monoclonal antibody derived from a hemophilia a patient with inhibitor
-
Jacquemin MG, Desqueper BG, Benhida A, Vander Elst L, Hoylaerts MF, Bakkus M, Thielemans K, Arnout J, Peerlinck K, Gilles JGG, Vermylen J, Saint-Remy J-MR. Mechanism and kinetics of factor viii inactivation: study with an igg4 monoclonal antibody derived from a hemophilia a patient with inhibitor. Blood 1998; 92: 496-506.
-
(1998)
Blood
, vol.92
, pp. 496-506
-
-
Jacquemin, M.G.1
Desqueper, B.G.2
Benhida, A.3
Vander Elst, L.4
Hoylaerts, M.F.5
Bakkus, M.6
Thielemans, K.7
Arnout, J.8
Peerlinck, K.9
Gilles, J.G.G.10
Vermylen, J.11
Saint-Remy, J.-M.12
-
28
-
-
0029957538
-
Further characterization of factor VIII-deficient mice created by gene targeting: RNA and protein studies
-
Bi L, Sarkar R, Naas T, Lawler AM, Pain J, Shumaker SL, Bedian V, Kazazian HH Jr. Further characterization of factor VIII-deficient mice created by gene targeting: RNA and protein studies. Blood 1996; 88: 3446-50.
-
(1996)
Blood
, vol.88
, pp. 3446-3450
-
-
Bi, L.1
Sarkar, R.2
Naas, T.3
Lawler, A.M.4
Pain, J.5
Shumaker, S.L.6
Bedian, V.7
Kazazian Jr, H.H.8
-
29
-
-
14744302512
-
Rescuing transgene expression by co-integration
-
Clark AJ, Cowper A, Wallac R, Wright G, Simons JP. Rescuing transgene expression by co-integration. J Biotechnol 1992; 10: 1450-4.
-
(1992)
J Biotechnol
, vol.10
, pp. 1450-1454
-
-
Clark, A.J.1
Cowper, A.2
Wallac, R.3
Wright, G.4
Simons, J.P.5
-
30
-
-
0030999953
-
Transgene rescue in the mammary gland is associated with transcription but does not require translation of BLG transgenes
-
Yull F, Binas B, Harold G, Wallace R, Clark AJ. Transgene rescue in the mammary gland is associated with transcription but does not require translation of BLG transgenes. Transgenic Res 1997; 6: 11-17.
-
(1997)
Transgenic Res
, vol.6
, pp. 11-17
-
-
Yull, F.1
Binas, B.2
Harold, G.3
Wallace, R.4
Clark, A.J.5
-
31
-
-
3242781567
-
Overcoming the immunological barriers to curing haemophilia
-
In: Studies TSIfB, ed. La Jolla, CA: The Salk Institute for Biological Studies
-
Alpan O, Velander WH, van Cott KE, Butler SP, High KA, Sabatino D. Overcoming the immunological barriers to curing haemophilia. In: Studies TSIfB, ed. 6th Gene Therapy Workshop. La Jolla, CA: The Salk Institute for Biological Studies, 2002: 3885-91.
-
(2002)
6th Gene Therapy Workshop
, pp. 3885-3891
-
-
Alpan, O.1
Velander, W.H.2
van Cott, K.E.3
Butler, S.P.4
High, K.A.5
Sabatino, D.6
-
34
-
-
0024574093
-
Expression of human anti-hemophilic factor mix in the milk of transgenic sheep
-
Clark AJ, Bessos H, Bishop JO, Brown P, Lathe HR, McClenaghan M, Prowse C, Simons JP, Whitelaw CBA, Wilmut I. Expression of human anti-hemophilic factor mix in the milk of transgenic sheep. J Biotechnol 1989; 7: 487-92.
-
(1989)
J Biotechnol
, vol.7
, pp. 487-492
-
-
Clark, A.J.1
Bessos, H.2
Bishop, J.O.3
Brown, P.4
Lathe, H.R.5
McClenaghan, M.6
Prowse, C.7
Simons, J.P.8
Whitelaw, C.B.A.9
Wilmut, I.10
-
35
-
-
0017754787
-
Stabilization of factor VIII in plasma by the von Willebrand factor. Studies on posttransfusion and dissociated factor VIII and in patients with von Willebrand's disease
-
Weiss HJ, Sussman II, Hoyer LW. Stabilization of factor VIII in plasma by the von Willebrand factor. Studies on posttransfusion and dissociated factor VIII and in patients with von Willebrand's disease. J Clin Invest 1977; 60: 390-404.
-
(1977)
J Clin Invest
, vol.60
, pp. 390-404
-
-
Weiss, H.J.1
Sussman, I.I.2
Hoyer, L.W.3
-
36
-
-
0025924755
-
Sulfation of Tyr1680 of human blood coagulation factor VIII is essential for the interaction of factor VIII with von Willebrand factor
-
Leyte A, van Schijndel HB, Niehrs C, Huttner WB, Verbeet MP, Mertens K, van Mourik JA. Sulfation of Tyr1680 of human blood coagulation factor VIII is essential for the interaction of factor VIII with von Willebrand factor. J Biol Chem 1991; 266: 740-6.
-
(1991)
J Biol Chem
, vol.266
, pp. 740-746
-
-
Leyte, A.1
van Schijndel, H.B.2
Niehrs, C.3
Huttner, W.B.4
Verbeet, M.P.5
Mertens, K.6
van Mourik, J.A.7
-
37
-
-
80055106618
-
First attempt at immune tolerance induction with factor VIII/von Willebrand factor concentrates in hemophilia A children with high-titer inhibitors
-
Platokouki H, Pergantou H, Komitopoulou A, Xafaki P. First attempt at immune tolerance induction with factor VIII/von Willebrand factor concentrates in hemophilia A children with high-titer inhibitors. J Coagulation Disord 2010; 2: 35-40.
-
(2010)
J Coagulation Disord
, vol.2
, pp. 35-40
-
-
Platokouki, H.1
Pergantou, H.2
Komitopoulou, A.3
Xafaki, P.4
-
38
-
-
33747171681
-
Production of recombinant therapeutic proteins in the milk of transgenic animals
-
2, 4, 6.
-
Echelard Y, Ziomek CA, Meade HM. Production of recombinant therapeutic proteins in the milk of transgenic animals. BioPharm Int. 2006; 19: 36-40, 2, 4, 6.
-
(2006)
BioPharm Int
, vol.19
, pp. 36-40
-
-
Echelard, Y.1
Ziomek, C.A.2
Meade, H.M.3
-
39
-
-
45749147034
-
Analysis of the N-glycans of recombinant human factor IX purified from transgenic pig milk
-
Gil GC, Velander WH, van Cott KE. Analysis of the N-glycans of recombinant human factor IX purified from transgenic pig milk. Glycobiology 2008; 18: 526-39.
-
(2008)
Glycobiology
, vol.18
, pp. 526-539
-
-
Gil, G.C.1
Velander, W.H.2
van Cott, K.E.3
-
40
-
-
0033623288
-
Alpha 3-galactosylated glycoproteins can bind to the hepatic asialoglycoprotein receptor
-
Joziasse DH, Lee RT, Lee YC, Biessen EAL, Schiphorst WECM, Koeleman CAM, van den Eijnden DH. Alpha 3-galactosylated glycoproteins can bind to the hepatic asialoglycoprotein receptor. Eur J Biochem 2000; 267: 6501-8.
-
(2000)
Eur J Biochem
, vol.267
, pp. 6501-6508
-
-
Joziasse, D.H.1
Lee, R.T.2
Lee, Y.C.3
Biessen, E.A.L.4
Schiphorst, W.E.C.M.5
Koeleman, C.A.M.6
van den Eijnden, D.H.7
|