Prevalence of intentional under- and overdosing of insulin in children and adolescents with type 1 diabetes

Pediatric Diabetes

Volumn 12, Issue 7, 2011, Pages 627-631

  Schober, Edith ^a   Wagner, Gudrun ^b   Berger, Gabriele ^b   Gerber, Daniela ^b   Mengl, Marlene ^b   Sonnenstatter, Sarah ^b   Barrientos, Irene ^a   Rami, Birgit ^a   Karwautz, Andreas ^b   Fritsch, Maria ^a  

^a UNIV KLIN KINDER JUGENDHEILKUNDE   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Adolescents; Children; Insulin misuse; Type 1 diabetes

Indexed keywords

HEMOGLOBIN A1C; INSULIN;

ADOLESCENT; ADULT; ARTICLE; BODY HEIGHT; BODY WEIGHT; CHILD; CHILD BEHAVIOR; CROSS-SECTIONAL STUDY; DIABETES SELF MANAGEMENT PROFILE; DRUG DOSE REGIMEN; FEMALE; GROUPS BY AGE; HEMOGLOBIN BLOOD LEVEL; HUMAN; HYPOGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; INTERVIEW; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PATIENT COMPLIANCE; PREVALENCE; PRIORITY JOURNAL; RATING SCALE; SCHOOL CHILD; SELF MEDICATION; SEX DIFFERENCE;

ADOLESCENT; AUSTRIA; CHILD; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 1; FEMALE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; MALE; MEDICATION ADHERENCE; SELF CARE; YOUNG ADULT;

EID: 80055096728     PISSN: 1399543X     EISSN: 13995448     Source Type: Journal    
DOI: 10.1111/j.1399-5448.2011.00759.x     Document Type: Article

References (25)

1. Silverstein J, Klingensmith G, Copeland K et al. Care of children and adolescents with type 1 diabetes. A statement of the American Diabetes Association. Diabetes Care 2005: 28: 186-212.
2. de Beaufort CE, Swift PG, Skinner CT et al. Continuing stability of centre differences in pediatric diabetes care: do advances in diabetes treatment improve outcome? The Hvidoere Study Group on Childhood Diabetes. Diabetes Care 2007: 30: 2245-2250.
3. Comeaux SJ, Jaser SS. Autonomy and insulin in adolescents with type 1 diabetes. Pediatr Diabetes 2010: 11: 498-504.
4. Anderson BJ, Svoren B, Laffel L. Initiatives to promote effective selfcare skills in children and adolescents with diabetes mellitus. Dis Manage Health Outcomes 2007: 15: 101-108.
5. Neumark-Sztainer D, Patterson J, Mellin A et al. Weight control practices and disordered eating behaviors among adolescent females and males with type 1 diabetes: associations with sociodemographics, weight concerns, familial factors, and metabolic outcomes. Diabetes Care 2002: 25: 1289-1296.
6. Herpertz S, Albus C, Wagener R et al. Comorbidity of diabetes and eating disorders. Does diabetes control reflect disturbed eating behavior? Diabetes Care 1998: 21: 1110-1106.
7. Peyrot M, Rubib RR, Kruger DF, Travis LB. Correlates of insulin injection omission. Diabetes Care 2010: 33: 240-245.
8. Von Mach MA, Meyer S, Omogbehin B, Kann PH, Weilemann LS. Epidemiological assessment of 160 cases of insulin overdose recorded in a regional poisons unit. Int J Clin Pharmacol Ther 2004: 42: 277-280.
9. Russell KS, Stevens JR, Stern THA. Insulin overdose among patients with diabetes: a readily available means of suicide. J Clin Psychiatry 2009: 11: 258-262.
10. Boileau P, Aboumrad B, Bougneres P. Recurrent comas due to secret self-administration of insulin in adolescents with type 1 diabetes. Diabetes Care 2006: 29: 430-431.
11. Franklin VL, Bluff S, Ramsay V, Sturrock C, Greene SA, Alexander V. Unexplained hypoglycaemia on a pump. Pediatr Diabetes 2007: 8: 391-392.
12. Orr DP, Eccles T, Lawlor R, Golden M. Surreptitious insulin administration in adolescents with insulin-dependent diabetes mellitus. Case report. J Am Med Assoc 1986: 256: 3227-3230.
13. Diabetes Research in Children Network (DirecNet) Study Group. DSMP - F: Diabetes Self-Management Profile for flexible insulin regimes. Cross-sectional and longitudinal analysis of psychometric properties in a pediatric sample. Diabetes Care 2005: 28: 2034-2035.
14. Morris AD, Boyle DIR, McMahon AD, Greene STA, MacDonald THM, Newton RW. Adherence to insulin treatment, glycemic control, and ketoacidosis in insulin-dependent diabetes mellitus. Lancet 1997: 350: 1505-1510.
15. VanderWel BW, Messer LH, Horton LA et al. Missed insulin boluses for snacks in youth with type 1 diabetes. Diabetes Care 2010: 33: 507-508.
16. Burdick J, Chase HP, Slover RH et al. Missed insulin meal boluses and elevated hemoglobin A1c levels in children receiving insulin pump therapy. Pediatrics 2004: 113: e221-e224.
17. Olinder AL, Kernell A, Smide B. Missed bolus doses: devastating for metabolic control in CSII-treated adolescents with type 1 diabetes. Pediatr Diabetes 2009: 10: 142-148.
18. Pankowska E, Skorka A, Szypowska A, Lipka M. Memory of insulin pumps and their record as a source of information about insulin therapy in children and adolescents with type 1 diabetes. Diabetes Technol Ther 2005: 7: 308-314.
19. Chase HP, Horner B, McFann K et al. Use of insulin pumps with meal bolus alarms in children with type 1 diabetes to improve glycemic control. Diabetes Care 2006: 29: 1012-1015.
20. Palmer DL, Berg CA, Wiebe DJ et al. The role of autonomy and pubertal status in understanding age differences in maternal involvement in diabetes responsibility across adolescence. J Pediatr Psychol 2004: 29: 35-46.
21. McNally K, Rohan J, Pendley JS, Delamater A, Drotar D. Executive functioning, treatment adherence, and glycemic control in children with type 1 diabetes. Diabetes Care 2010: 33: 1159-1162.
22. Goldston DB, Kovacs M, Ho VY, Parrone PL, Stiffler L. Suicidal ideation and suicide attempts among youth with insulin-dependent diabetes mellitus. J Am Acad Child Adolesc Psychiatry 1994: 33: 240-246.
23. Osipoff JN, Sattar N, Garcia M, Wilson Th. Prime-time hypoglycaemia: factitious hypoglycemia during insulin pump therapy. Pediatrics 2010: 125: e1246-e1248.
24. Scaramuzza A, Castellani G, Lorini R. Insulin abuse in an adolescent with insulin-dependent diabetes mellitus. Case report. Eur J Pediatr 1996: 155: 526.
25. Cassidy EM, O'Halloran DJ, Barry S. Insulin as a substance of misuse in a patient with insulin dependent diabetes mellitus. Case report. Br Med J 1999: 319: 1417-1418.