Evaluation of intra-articular mesenchymal stem cells to augment healing of microfractured chondral defects

Arthroscopy - Journal of Arthroscopic and Related Surgery

Volumn 27, Issue 11, 2011, Pages 1552-1561

  McIlwraith, C Wayne ^a   Frisbie, David D ^a   Rodkey, William G ^b   Kisiday, John D ^a   Werpy, Natasha M ^a   Kawcak, Christopher E ^a   Steadman, J Richard ^b  

^a Department of Ecosystem Science and Sustainability   (United States)

^b STEADMAN PHILIPPON RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECAN; HYALURONIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHROSCOPY; ARTICLE; BIOCHEMISTRY; BONE MARROW DERIVED MESENCHYMAL STEM CELL THERAPY; CHONDROPATHY; FRACTURE HEALING; HISTOLOGY; HORSE; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; JOINT RADIOGRAPHY; MESENCHYMAL STEM CELL TRANSPLANTATION; MICROFRACTURE; MORPHOMETRICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; TISSUE REPAIR; TREADMILL EXERCISE; WALKING;

ANIMALS; ARTHROSCOPY; BONE MARROW TRANSPLANTATION; CARTILAGE; HORSES; HYALURONIC ACID; INJECTIONS, INTRA-ARTICULAR; INTRA-ARTICULAR FRACTURES; KNEE INJURIES; MAGNETIC RESONANCE IMAGING; MESENCHYMAL STEM CELL TRANSPLANTATION; MODELS, ANIMAL; ORTHOPEDIC PROCEDURES; RANDOM ALLOCATION; SINGLE-BLIND METHOD; STIFLE; SYNOVIAL MEMBRANE; TREATMENT OUTCOME; VISCOSUPPLEMENTS; WOUND HEALING;

EID: 80055095806     PISSN: 07498063     EISSN: 15263231     Source Type: Journal    
DOI: 10.1016/j.arthro.2011.06.002     Document Type: Article

References (27)

1. J.R. Steadman, K.K. Briggs, J.J. Rodrigo, M.S. Kocher, T.J. Gill, and W.G. Rodkey Outcomes of microfracture for traumatic chondral defects of the knee: Average 11-year follow-up Arthroscopy 19 2003 477 484 (Pubitemid 36560399)
2. J.R. Steadman, W.G. Rodkey, and K.K. Briggs Microfracture chondroplasty: Indications, techniques, and outcomes Sports Med Arthrosc Rev 11 2003 236 244 (Pubitemid 37461440)
3. J.R. Steadman, W.G. Rodkey, and K.K. Briggs Microfracture to treat full-thickness chondral defects: Surgical technique, rehabilitation, and outcomes J Knee Surg 15 2002 170 176
4. J.R. Steadman, W.G. Rodkey, K.K. Briggs, and J.J. Rodrigo Debridement and microfracture for full-thickness articular cartilage defects W.N. Scott, Insall & Scott surgery of the knee 2006 Churchill Livingstone Elsevier Philadelphia, PA 359 366
5. J.R. Steadman, W.G. Rodkey, and K.K. Briggs Microfracture: Its history and experience of the developing surgeon Cartilage 1 2010 78 86
6. A. Bedi, B.T. Feeley, and R.J. Williams III Management of articular cartilage defects of the knee J Bone Joint Surg Am 92 2010 994 1009
7. P.J. Millett, B.H. Huffard, M.P. Horan, R.J. Hawkins, and J.R. Steadman Outcomes of full-thickness articular cartilage injuries of the shoulder treated with microfracture Arthroscopy 25 2009 856 863
8. D.D. Frisbie, G.W. Trotter, and B.E. Powers Arthroscopic subchondral bone plate microfracture technique augments healing of large chondral defects in the radial carpal bone and medial femoral condyle of horses Vet Surg 28 1999 242 255 (Pubitemid 129742505)
9. D.D. Frisbie, J.T. Oxford, and L. Southwood Early events in cartilage repair after subchondral bone microfracture Clin Orthop Relat Res 2003 215 227 (Pubitemid 36176512)
10. D.D. Frisbie, S. Morisset, C.P. Ho, W.G. Rodkey, J.R. Steadman, and C.W. McIlwraith Effects of calcified cartilage on healing of chondral defects treated with microfracture in horses Am J Sports Med 34 2006 1824 1831 (Pubitemid 44735523)
11. S. Morisset, D.D. Frisbie, P.D. Robbins, A.J. Nixon, and C.W. McIlwraith IL-1Ra/IGF-1 gene therapy modulates repair of microfractured chondral defects Clin Orthop Relat Res 462 2007 221 228 (Pubitemid 47367867)
12. M. Agung, M. Ochi, and S. Yanada Mobilization of bone marrow-derived mesenchymal stem cells into the injured tissues after intraarticular injection and their contribution to tissue regeneration Knee Surg Sports Traumatol Arthrosc 14 2006 1307 1314 (Pubitemid 44800660)
13. C.W. McIlwraith, and D.D. Frisbie Microfracture: Basic science studies in the horse Cartilage 1 2010 87 95
14. T. Yamasaki, M. Deie, and R. Shinomiya Meniscal regeneration using tissue engineering with a scaffold derived from a rat meniscus and mesenchymal stromal cells derived from rat bone marrow J Biomed Mater Res A 75 2005 23 30 (Pubitemid 41298184)
15. Y. Izuta, M. Ochi, N. Adachi, M. Deie, T. Yamasaki, and R. Shinomiya Meniscal repair using bone marrow-derived mesenchymal stem cells: Experimental study using green fluorescent protein transgenic rats Knee 12 2005 217 223 (Pubitemid 40720230)
16. J.M. Murphy, D.J. Fink, E.B. Hunziker, and F.P. Barry Stem cell therapy in a caprine model of osteoarthritis Arthritis Rheum 48 2003 3464 3474 (Pubitemid 37531912)
17. M.M. Wilke, D.V. Nydam, and A.J. Nixon Enhanced early chondrogenesis in articular defects following arthroscopic mesenchymal stem cell implantation in an equine model J Orthop Res 25 2007 913 925 (Pubitemid 47046438)
18. J.D. Kisiday, B.W. Hale, and J.L. Almodovar Expansion of mesenchymal stem cells on fibrinogen-rich protein surfaces derived from blood plasma J Tissue Eng Regen Med 5 2011 600 611
19. K.B. Lee, J.H. Hui, I.C. Song, L. Ardany, and E.H. Lee Injectable mesenchymal stem cell therapy for large cartilage defectsA porcine model Stem Cells 25 2007 2964 2971 (Pubitemid 350127882)
20. K.Y. Saw, P. Hussin, and S.C. Loke Articular cartilage regeneration with autologous marrow aspirate and hyaluronic acid: An experimental study in a goat model Arthroscopy 25 2009 1391 1400
21. M. Jung, B. Kaszap, and A. Redöhl Enhanced early tissue regeneration after matrix-assisted autologous mesenchymal stem cell transplantation in full thickness chondral defects in a minipig model Cell Transplant 18 2009 923 932
22. S.W. O'Driscoll, F.W. Keeley, and R.B. Salter The chondrogenic potential of free autogenous periosteal grafts for biological resurfacing of major full-thickness defects in joint surfaces under the influence of continuous passive motion An experimental investigation in the rabbit J Bone Joint Surg Am 68 1986 1017 1035 (Pubitemid 17180051)
23. S.W. O'Driscoll, F.W. Keeley, and R.B. Salter Durability of regenerated articular cartilage produced by free autogenous periosteal grafts in major full-thickness defects in joint surfaces under the influence of continuous passive motion A follow-up report at one year J Bone Joint Surg Am 70 1988 595 606
24. A.I. Caplan, and J.E. Dennis Mesenchymal stem cells as trophic mediators J Cell Biochem 98 2006 1076 1084 (Pubitemid 44128350)
25. S.C. Pitchford, R.C. Furze, C.P. Jones, A.M. Wengner, and S.M. Rankin Differential mobilization of subsets of progenitor cells from the bone marrow Cell Stem Cell 4 2009 62 72
26. D.D. Frisbie, J.D. Kisiday, C.E. Kawcak, C.W. McIlwraith, and N.M. Werpy Evaluation of adipose-derived stromal vascular fraction or bone marrow-derived mesenchymal stem cells for treatment of osteoarthritis J Orthop Res 27 2009 1675 1680
27. P.W. Kopesky, H.Y. Lee, and E.J. Vanderploeg Adult equine bone marrow stromal cells produce a cartilage-like ECM mechanically superior to animal-matched adult chondrocytes Matrix Biol 29 2010 427 438