-
1
-
-
0033517302
-
The effect of spironolactone on morbidity and mortality in patients with severe heart failure
-
RALES Study Group
-
Pitt B, Zannad F, Remme WJ, et al; RALES Study Group. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. N Engl J Med. 1999;341:709-717.
-
(1999)
N Engl J Med
, vol.341
, pp. 709-717
-
-
Pitt, B.1
Zannad, F.2
Remme, W.J.3
-
2
-
-
0028781727
-
Disorders of aldosterone biosynthesis and action
-
White PC. Disorders of aldosterone biosynthesis and action. N Engl J Med. 1994;331:250-258.
-
(1994)
N Engl J Med
, vol.331
, pp. 250-258
-
-
White, P.C.1
-
3
-
-
0038179527
-
Eplerenone: Cardiovascular protection
-
Brown NJ. Eplerenone: Cardiovascular protection. Circulation. 2003; 107:2512-2518.
-
(2003)
Circulation
, vol.107
, pp. 2512-2518
-
-
Brown, N.J.1
-
4
-
-
0026707576
-
Atrial natriuretic peptide-induced inhibition of aldosterone secretion: A quest for mediator(s)
-
Ganguly A. Atrial natriuretic peptide-induced inhibition of aldosterone secretion: A quest for mediator(s). Am J Physiol. 1992;263:e181-e194.
-
(1992)
Am J Physiol
, vol.263
-
-
Ganguly, A.1
-
5
-
-
0025071790
-
Renin release from microdissected, superficial, midcortical, and juxtamedullary afferent arterioles in rabbits
-
Nushiro N, Ito S, Carretero OA. Renin release from microdissected, superficial, midcortical, and juxtamedullary afferent arterioles in rabbits. Kidney Int. 1990;38;426-431.
-
(1990)
Kidney Int
, vol.38
, pp. 426-431
-
-
Nushiro, N.1
Ito, S.2
Carretero, O.A.3
-
6
-
-
0026077306
-
Angiotensin actions in the kidney: Renewed insight into the old hormone
-
Ichikawi I. Angiotensin actions in the kidney: Renewed insight into the old hormone. Kidney Int. 1991;40:583-596.
-
(1991)
Kidney Int
, vol.40
, pp. 583-596
-
-
Ichikawi, I.1
-
7
-
-
0027208070
-
Angiotensin II receptors and angiotensin II receptor antagonists
-
Timmermans PB, Wong PC, Chiu AT, et al. Angiotensin II receptors and angiotensin II receptor antagonists. Pharmacol Rev. 1993;45: 205-251.
-
(1993)
Pharmacol Rev
, vol.45
, pp. 205-251
-
-
Timmermans, P.B.1
Wong, P.C.2
Chiu, A.T.3
-
8
-
-
0027397544
-
Inositol trisphosphate and calcium signaling
-
Berridge MJ. Inositol trisphosphate and calcium signaling. Nature. 1993;361:315-325.
-
(1993)
Nature
, vol.361
, pp. 315-325
-
-
Berridge, M.J.1
-
9
-
-
0029902697
-
Aldosterone and potassium homeostasis
-
Rabinowitz L. Aldosterone and potassium homeostasis. Kidney Int. 1996;49:1738-1742.
-
(1996)
Kidney Int
, vol.49
, pp. 1738-1742
-
-
Rabinowitz, L.1
-
11
-
-
18844465310
-
Multiplicative interaction between angiotensin II and K concentration in stimulation of aldosterone
-
Young DB, Smith MJ Jr, Jackson TE, Scott RE. Multiplicative interaction between angiotensin II and K concentration in stimulation of aldosterone. Am J Physiol. 1984;247(3 Pt 1):E328-E335.
-
(1984)
Am J Physiol
, vol.247
, Issue.3 PART 1
-
-
Young, D.B.1
Smith Jr., M.J.2
Jackson, T.E.3
Scott, R.E.4
-
12
-
-
0024384384
-
Production of renin, angiotensin II and aldosterone by adrenal explant cultures: Response to potassium and converting enzyme inhibition
-
Shier DN, Kusano E, Stoner GD, Franco-Saenz R, Mulrow PJ. Production of renin, angiotensin II and aldosterone by adrenal explant cultures: Response to potassium and converting enzyme inhibition. Endocrinology. 1989;125:486-491.
-
(1989)
Endocrinology
, vol.125
, pp. 486-491
-
-
Shier, D.N.1
Kusano, E.2
Stoner, G.D.3
Franco-Saenz, R.4
Mulrow, P.J.5
-
14
-
-
0026634731
-
The cellular action of aldosterone in target epithelia
-
Bastl CP, Hayslett JP. The cellular action of aldosterone in target epithelia. Kidney Int. 1992;42;250-264.
-
(1992)
Kidney Int
, vol.42
, pp. 250-264
-
-
Bastl, C.P.1
Hayslett, J.P.2
-
15
-
-
0026692172
-
Aldosterone regulation of gene transcription leading to control of ion transport
-
Horisberger JD, Rossier BC. Aldosterone regulation of gene transcription leading to control of ion transport. Hypertension. 1992;19:221-227.
-
(1992)
Hypertension
, vol.19
, pp. 221-227
-
-
Horisberger, J.D.1
Rossier, B.C.2
-
16
-
-
50549174396
-
Aldosterone in fluid and electrolyte disorders: Hyper and hypoaldosteronism
-
Laragh JH. Aldosterone in fluid and electrolyte disorders: Hyper and hypoaldosteronism. J Clin Dis. 1960;11:292-318.
-
(1960)
J Clin Dis
, vol.11
, pp. 292-318
-
-
Laragh, J.H.1
-
17
-
-
73849162980
-
Cirrhosis for renal-adrenal interaction from studies in hypertension and in failure: Vasopressin, aldosterone, and angiotensin II: Further evidence hormones and the pathogenesis of congestive heart
-
Laragh JH. Cirrhosis for renal-adrenal interaction from studies in hypertension and in failure: Vasopressin, aldosterone, and angiotensin II: further evidence hormones and the pathogenesis of congestive heart. Circulation. 1962;25:1015-1023.
-
(1962)
Circulation
, vol.25
, pp. 1015-1023
-
-
Laragh, J.H.1
-
18
-
-
0021809938
-
Sodium-dependent modulation of the renal Na-K-ATPase: Influence of mineralocorticoids on the cortical collecting duct
-
O'Neil RG, Hayhurst RA. Sodium-dependent modulation of the renal Na-K-ATPase: Influence of mineralocorticoids on the cortical collecting duct. J Membr Biol. 1985;8:169-179.
-
(1985)
J Membr Biol
, vol.8
, pp. 169-179
-
-
O'Neil, R.G.1
Hayhurst, R.A.2
-
19
-
-
0027081410
-
Mineral ocorticoid excess, dietarysodium and myocardial fibrosis
-
Brilla CG, Weber KT. Mineral ocorticoid excess, dietarysodium and myocardial fibrosis. J Lab Clin Med. 1992;120:893-901.
-
(1992)
J Lab Clin Med
, vol.120
, pp. 893-901
-
-
Brilla, C.G.1
Weber, K.T.2
-
20
-
-
0027227646
-
Anti-aldosteronetreatment and the prevention of myocardial fibrosis in primary and secondary ldosteronism
-
Brilla CG, Matsubara LS, Weber KT. Anti-aldosteronetreatment and the prevention of myocardial fibrosis in primary and secondary ldosteronism. J Mol Cell Cardiol. 1993;25:563-575.
-
(1993)
J Mol Cell Cardiol
, vol.25
, pp. 563-575
-
-
Brilla, C.G.1
Matsubara, L.S.2
Weber, K.T.3
-
21
-
-
0028840698
-
Biological determinants of aldosterone-induced cardiac fibrosis in rats
-
Robert V, Silvestre JS, Charlemagne D, et al. Biological determinants of aldosterone-induced cardiac fibrosis in rats. Hypertension. 1995;26 (6 Pt 1):971-978.
-
(1995)
Hypertension
, vol.26
, Issue.6 PART 1
, pp. 971-978
-
-
Robert, V.1
Silvestre, J.S.2
Charlemagne, D.3
-
22
-
-
0028290539
-
Mineralocorticoids, hypertension, and cardiac fibrosis
-
Young M, Fullerton M, Dilley R, Funder J. Mineralocorticoids, hypertension, and cardiac fibrosis. J Clin Invest. 1994;93:2578-2583.
-
(1994)
J Clin Invest
, vol.93
, pp. 2578-2583
-
-
Young, M.1
Fullerton, M.2
Dilley, R.3
Funder, J.4
-
23
-
-
0032588244
-
Angiotensin AT1 receptor subtype as a cardiac target of aldosterone: Role in aldosterone-salt-induced fibrosis
-
Robert V, Heymes C, Silvestre JS, Sabri A, Swynghedauw B, Delcarye C. Angiotensin AT1 receptor subtype as a cardiac target of aldosterone: Role in aldosterone-salt-induced fibrosis. Hypertension. 1999;33:981-986.
-
(1999)
Hypertension
, vol.33
, pp. 981-986
-
-
Robert, V.1
Heymes, C.2
Silvestre, J.S.3
Sabri, A.4
Swynghedauw, B.5
Delcarye, C.6
-
24
-
-
0030809598
-
Fibrosis of atria and great vessels in response to angiotensin II or aldosterone infusion
-
Sun Y, Ramiers F, Weber KT. Fibrosis of atria and great vessels in response to angiotensin II or aldosterone infusion. Cardiovasc Res. 1997;35:138-147.
-
(1997)
Cardiovasc Res
, vol.35
, pp. 138-147
-
-
Sun, Y.1
Ramiers, F.2
Weber, K.T.3
-
25
-
-
0036791717
-
Spironolactone improves angiotensin-induced vascular changes and oxidative stress
-
Virdis A, Neves MF, Amiri F, Viel E, Touyz RM, Schiffrin EL. Spironolactone improves angiotensin-induced vascular changes and oxidative stress. Hypertension. 2002;40:504-510.
-
(2002)
Hypertension
, vol.40
, pp. 504-510
-
-
Virdis, A.1
Neves, M.F.2
Amiri, F.3
Viel, E.4
Touyz, R.M.5
Schiffrin, E.L.6
-
26
-
-
0035838423
-
Aldosterone induces angiotensinconverting enzyme gene expression in cultured neonatal rat cardiocytes
-
Harda E, Yoshimura M, Yasue H, et al. Aldosterone induces angiotensinconverting enzyme gene expression in cultured neonatal rat cardiocytes. Circulation. 2001;104:137-139.
-
(2001)
Circulation
, vol.104
, pp. 137-139
-
-
Harda, E.1
Yoshimura, M.2
Yasue, H.3
-
27
-
-
77951822096
-
Aldosterone and cardiovascular disease
-
Carey RM. Aldosterone and cardiovascular disease. Curr Opin Endocrinol Diabetes Obes. 2010;17:194-198.
-
(2010)
Curr Opin Endocrinol Diabetes Obes
, vol.17
, pp. 194-198
-
-
Carey, R.M.1
-
28
-
-
24744471859
-
Aldosterone and angiotensin II synergistically induce mitogenic response in vascular smooth muscle cells
-
Min LJ, Mogi M, Li JM, Iwanami J, Iwai M, Horiuchi M. Aldosterone and angiotensin II synergistically induce mitogenic response in vascular smooth muscle cells. Circ Resp. 2005;97:434-442.
-
(2005)
Circ Resp
, vol.97
, pp. 434-442
-
-
Min, L.J.1
Mogi, M.2
Li, J.M.3
Iwanami, J.4
Iwai, M.5
Horiuchi, M.6
-
29
-
-
2142694344
-
Aldosterone enhances ischemia-induced neovascularization through angiotensin II-dependent pathway
-
Michel F, Amboisine ML, Duriez M, Delcayre C, Levy Bi, Silvestre JS. Aldosterone enhances ischemia-induced neovascularization through angiotensin II-dependent pathway. Circulation. 2004;109:1933-1937.
-
(2004)
Circulation
, vol.109
, pp. 1933-1937
-
-
Michel, F.1
Amboisine, M.L.2
Duriez, M.3
Delcayre, C.4
Bi, L.5
Silvestre, J.S.6
-
30
-
-
35548992302
-
Cross-talk between aldosterone and angiotensin II in vascular smooth muscle cell senescence
-
Min LJ, Mogi M, Iwanami J, et al. Cross-talk between aldosterone and angiotensin II in vascular smooth muscle cell senescence. Cardiovasc Res. 2007;76:506-516.
-
(2007)
Cardiovasc Res
, vol.76
, pp. 506-516
-
-
Min, L.J.1
Mogi, M.2
Iwanami, J.3
-
31
-
-
31944432456
-
Nongenomic effects of aldosterone in the human heart: Interaction with angiotensin II
-
Chai W, Garrelds IM, de Vries R, Batenburg WW, van Kats JP, Danser AH. Nongenomic effects of aldosterone in the human heart: Interaction with angiotensin II. Hypertension. 2005;46:701-706.
-
(2005)
Hypertension
, vol.46
, pp. 701-706
-
-
Chai, W.1
Garrelds, I.M.2
de Vries, R.3
Batenburg, W.W.4
van Kats, J.P.5
Danser, A.H.6
-
32
-
-
0037300633
-
Aldosterone induces contraction of the resistance arteries in man
-
Romagni P, Rossi F, Guerrini L, Quirini C, Santiemma V. Aldosterone induces contraction of the resistance arteries in man. Athero sclerosis. 2003;166:345-349.
-
(2003)
Athero sclerosis
, vol.166
, pp. 345-349
-
-
Romagni, P.1
Rossi, F.2
Guerrini, L.3
Quirini, C.4
Santiemma, V.5
-
33
-
-
21744443964
-
Aldosterone nongenomically worsens ischemia via protein kinase C-dependent pathways in hypoperfused canine hearts
-
Fujita M, Minamino T, Asanuma H, et al. Aldosterone nongenomically worsens ischemia via protein kinase C-dependent pathways in hypoperfused canine hearts. Hypertension. 2005;46:113-117.
-
(2005)
Hypertension
, vol.46
, pp. 113-117
-
-
Fujita, M.1
Minamino, T.2
Asanuma, H.3
-
34
-
-
42349101107
-
A comparison of the aldosteroneblocking agents eplerenone and spironolactone
-
Struthers A, Krum H, Williams GH. A comparison of the aldosteroneblocking agents eplerenone and spironolactone. Clin Cardiol. 2008;31:153-158.
-
(2008)
Clin Cardiol
, vol.31
, pp. 153-158
-
-
Struthers, A.1
Krum, H.2
Williams, G.H.3
-
35
-
-
0035818917
-
Aldosterone in congestive heart failure
-
Weber KT. Aldosterone in congestive heart failure. N Engl J Med. 2001;345:1689-1697.
-
(2001)
N Engl J Med
, vol.345
, pp. 1689-1697
-
-
Weber, K.T.1
-
36
-
-
0000452493
-
Splanchnic extraction and clearance of aldosterone in subjects with minimal and marked cardiac dysfunction
-
Tait JF, Little B, Tait SAS, Flood C, Bougas J. Splanchnic extraction and clearance of aldosterone in subjects with minimal and marked cardiac dysfunction. J Clin Endocrinol Metab. 1965;25:219-228.
-
(1965)
J Clin Endocrinol Metab
, vol.25
, pp. 219-228
-
-
Tait, J.F.1
Little, B.2
Tait, S.A.S.3
Flood, C.4
Bougas, J.5
-
37
-
-
0025088737
-
Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality
-
CONSENSUS Study Group
-
Swedberg K, Eneroth P, Kjekshus J, Wilhelmsen L; CONSENSUS Study Group. Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. Circulation. 1990;82:1730-1736.
-
(1990)
Circulation
, vol.82
, pp. 1730-1736
-
-
Swedberg, K.1
Eneroth, P.2
Kjekshus, J.3
Wilhelmsen, L.4
-
38
-
-
0032885976
-
Involvement of aldosterone in left ventricular hypertrophy of patients with end-stage renal failure treated with hemodialysis
-
Sato A, Funder JW, Saruta T. Involvement of aldosterone in left ventricular hypertrophy of patients with end-stage renal failure treated with hemodialysis. Am J Hypertens. 1999;12(9 Pt 1):867-873.
-
(1999)
Am J Hypertens
, vol.12
, Issue.9 PART 1
, pp. 867-873
-
-
Sato, A.1
Funder, J.W.2
Saruta, T.3
-
39
-
-
72549105303
-
Aldosterone and cardiovascular risk
-
Vogt B, Burnier M. Aldosterone and cardiovascular risk. Curr Hypertens Rep. 2009;11:450-455.
-
(2009)
Curr Hypertens Rep
, vol.11
, pp. 450-455
-
-
Vogt, B.1
Burnier, M.2
-
40
-
-
0022181426
-
New insights into the pharmacokinetics of spironolactone
-
Overdiek H, Hermens W, Merkus F. New insights into the pharmacokinetics of spironolactone. Clin Pharmacol Ther. 1985;38:469-474.
-
(1985)
Clin Pharmacol Ther
, vol.38
, pp. 469-474
-
-
Overdiek, H.1
Hermens, W.2
Merkus, F.3
-
41
-
-
0024477650
-
Spironolactone metabolism: Steady-state serum levels of sulfur-containing metabolites
-
Gardiner P, Schrode K, Quinlan D, et al. Spironolactone metabolism: Steady-state serum levels of sulfur-containing metabolites. J Clin Pharmacol. 1989;29:342-347.
-
(1989)
J Clin Pharmacol
, vol.29
, pp. 342-347
-
-
Gardiner, P.1
Schrode, K.2
Quinlan, D.3
-
42
-
-
0015713162
-
Pharmacokinetics of spironolactone, canrenone and canrenoate-K in humans
-
Sadee W, Dagcioglu M, Schroder R. Pharmacokinetics of spironolactone, canrenone and canrenoate-K in humans. J Pharmacol Exp Ther. 1973;185:686-695.
-
(1973)
J Pharmacol Exp Ther
, vol.185
, pp. 686-695
-
-
Sadee, W.1
Dagcioglu, M.2
Schroder, R.3
-
45
-
-
21044433173
-
Pharmacokinetics of eplerenone after single and multiple dosing in subjects with and without renal impairment
-
Ravis WR, Reid S, Sica DA, Tolbert DS. Pharmacokinetics of eplerenone after single and multiple dosing in subjects with and without renal impairment. J Clin Pharmacol. 2005;45:810-821.
-
(2005)
J Clin Pharmacol
, vol.45
, pp. 810-821
-
-
Ravis, W.R.1
Reid, S.2
Sica, D.A.3
Tolbert, D.S.4
-
46
-
-
78650399880
-
Eplerenone in patients with systolic heart failure and mild symptoms
-
EMPHASIS-HF Study Group
-
Zannad F, McMurray J, Krum H, et al; EMPHASIS-HF Study Group. Eplerenone in patients with systolic heart failure and mild symptoms. N Engl J Med. 2011;364:11-21.
-
(2011)
N Engl J Med
, vol.364
, pp. 11-21
-
-
Zannad, F.1
McMurray, J.2
Krum, H.3
-
47
-
-
0017330993
-
Elimination of canrenone in congestive heart failure and chronic liver disease
-
Jackson L, Branch R, Levine D, Ramsay L. Elimination of canrenone in congestive heart failure and chronic liver disease. Eur J Clin Pharmacol. 1977;11:177-179.
-
(1977)
Eur J Clin Pharmacol
, vol.11
, pp. 177-179
-
-
Jackson, L.1
Branch, R.2
Levine, D.3
Ramsay, L.4
-
49
-
-
0023620145
-
Efficacy and tolerance of spironolactone in essential hypertension
-
Jeunemaitre X, Chatellier G, Kreft-Jais C, et al. Efficacy and tolerance of spironolactone in essential hypertension. Am J Cardiol. 1987; 60:820-825.
-
(1987)
Am J Cardiol
, vol.60
, pp. 820-825
-
-
Jeunemaitre, X.1
Chatellier, G.2
Kreft-Jais, C.3
-
50
-
-
0037417252
-
Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
-
EPHESUS Study Group
-
Pitt B, Remme W, Zannad F, et al; EPHESUS Study Group. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med. 2003;348:1309-1321.
-
(2003)
N Engl J Med
, vol.348
, pp. 1309-1321
-
-
Pitt, B.1
Remme, W.2
Zannad, F.3
-
51
-
-
0035997359
-
Eplerenone, a selective aldosterone blocker, in mild-to-moderate hypertension
-
Weinberger MH, Roniker B, Krause SL, Weiss RJ. Eplerenone, a selective aldosterone blocker, in mild-to-moderate hypertension. Am J Hypertens. 2002;15:709-716.
-
(2002)
Am J Hypertens
, vol.15
, pp. 709-716
-
-
Weinberger, M.H.1
Roniker, B.2
Krause, S.L.3
Weiss, R.J.4
-
52
-
-
0035810547
-
Effect of carvedilol on outcome after myocardial infarction in patients with left ventricular dysfunction
-
CAPRICORN Study Group
-
Dargie HJ; CAPRICORN Study Group. Effect of carvedilol on outcome after myocardial infarction in patients with left ventricular dysfunction. Lancet. 2001;357:1385-1390.
-
(2001)
Lancet
, vol.357
, pp. 1385-1390
-
-
Dargie, H.J.1
-
53
-
-
79953778324
-
Eplerenone in mild heart failure
-
Dastidar AG. Eplerenone in mild heart failure. N Engl J Med. 2011: 364:1370-1372.
-
(2011)
N Engl J Med
, vol.364
, pp. 1370-1372
-
-
Dastidar, A.G.1
-
54
-
-
77955891215
-
Executive summary: HFSA 2010 Comprehensive Heart Failure Practice Guideline
-
Lindenfeld J, Albert NM, Boehmer JP, et al. Executive summary: HFSA 2010 Comprehensive Heart Failure Practice Guideline. J Card Fail. 2010;16:e1-e194.
-
(2010)
J Card Fail
, vol.16
-
-
Lindenfeld, J.1
Albert, N.M.2
Boehmer, J.P.3
-
55
-
-
60749110418
-
Aldosterone blockade and left ventricular dysfunction: A systematic review of randomized clinical trials
-
Ezekowitz JA, McAlister FA. Aldosterone blockade and left ventricular dysfunction: A systematic review of randomized clinical trials. Eur Heart J. 2009;30:469-477.
-
(2009)
Eur Heart J
, vol.30
, pp. 469-477
-
-
Ezekowitz, J.A.1
McAlister, F.A.2
-
56
-
-
62449296975
-
Anti-remodelling effect of canrenone in patients with mild chronic heart failure (AREA IN-CHF study): Final results
-
AREA IN-CHF Study Group
-
Boccanelli A, Mureddu GF, Cacciatore G, et al; AREA IN-CHF Study Group. Anti-remodelling effect of canrenone in patients with mild chronic heart failure (AREA IN-CHF study): Final results. Eur J Heart Fail. 2009;11:68-76.
-
(2009)
Eur J Heart Fail
, vol.11
, pp. 68-76
-
-
Boccanelli, A.1
Mureddu, G.F.2
Cacciatore, G.3
-
57
-
-
77954739690
-
Randomized, doubleblind, multicenter, placebo-controlled study evaluating the effect of aldosterone antagonism with eplerenone on ventricular remodeling in patients with mild-to-moderate heart failure and left ventricular systolic dysfunction
-
Udelson JE, Feldman AM, Greenberg B, et al. Randomized, doubleblind, multicenter, placebo-controlled study evaluating the effect of aldosterone antagonism with eplerenone on ventricular remodeling in patients with mild-to-moderate heart failure and left ventricular systolic dysfunction. Circ Heart Fail. 2010;3:347-353.
-
(2010)
Circ Heart Fail
, vol.3
, pp. 347-353
-
-
Udelson, J.E.1
Feldman, A.M.2
Greenberg, B.3
-
59
-
-
42549117080
-
Retrospective review of the frequency of ECG changes in hyperkalemia
-
Montague BT, Ouellette JR, Buller GK. Retrospective review of the frequency of ECG changes in hyperkalemia. Clin J Am Soc Nephrol. 2008;3:324-330.
-
(2008)
Clin J Am Soc Nephrol
, vol.3
, pp. 324-330
-
-
Montague, B.T.1
Ouellette, J.R.2
Buller, G.K.3
|