A novel N,N-8-amino-8-demethyl-D-riboflavin dimethyltransferase (RosA) catalyzing the two terminal steps of roseoflavin biosynthesis in Streptomyces davawensis

Journal of Biological Chemistry

Volumn 286, Issue 44, 2011, Pages 38275-38285

  Jankowitsch, Frank ^a   Kühm, Christian ^a   Kellner, Roland ^b   Kalinowski, Jörn ^c   Pelzer, Stefan ^d   Macheroux, Peter ^e   Mack, Matthias ^a  

^a MANNHEIM UNIVERSITY OF APPLIED SCIENCES   (Germany)

^b Merck Serono GmbH   (Germany)

^c BIELEFELD UNIVERSITY   (Germany)

^d BRAIN AG   (Germany)

^e GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE FRACTION; APPARENT K; CELL-FREE EXTRACTS; DE NOVO SEQUENCING; ENZYMATIC DIGESTIONS; GENE CLUSTERS; GENE PRODUCTS; OPEN READING FRAME; PEPTIDE FRAGMENTS; RECOMBINANT E. COLI; TAGGED PROTEINS;

AMINO ACIDS; BACTERIA; BIOCHEMISTRY; COLUMN CHROMATOGRAPHY; ESCHERICHIA COLI; GENE EXPRESSION;

BIOSYNTHESIS;

8 AMINO 8 NORRIBOFLAVIN; 8 METHYLAMINO 8 NORRIBOFLAVIN; BACTERIAL ENZYME; POLYPEPTIDE ANTIBIOTIC AGENT; RIBOFLAVIN DERIVATIVE; ROSA PROTEIN; ROSEOFLAVIN; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL GENE; BACTERIAL GENOME; BIOSYNTHESIS; CATALYSIS; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; ENZYME INACTIVATION; ENZYME PURIFICATION; ESCHERICHIA COLI; GENE CLUSTER; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; ROSA GENE; SEQUENCE ANALYSIS; STREPTOMYCES; STREPTOMYCES DAVAWENSIS;

AMINO ACID SEQUENCE; CATALYSIS; ESCHERICHIA COLI; KINETICS; LIGANDS; METHYLTRANSFERASES; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; OPEN READING FRAMES; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; RIBOFLAVIN; SEQUENCE HOMOLOGY, AMINO ACID; STREPTOMYCES; TANDEM MASS SPECTROMETRY;

ESCHERICHIA COLI; STREPTOMYCES DAVAWENSIS;

EID: 80055078421     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.292300     Document Type: Article

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