The status of Tsukuba BNCT trial: BPA-based boron neutron capture therapy combined with X-ray irradiation

Applied Radiation and Isotopes

Volumn 69, Issue 12, 2011, Pages 1817-1818

  Yamamoto, T ^a   Nakai, K ^a   Nariai, T ^b   Kumada, H ^a   Okumura, T ^a   Mizumoto, M ^a   Tsuboi, K ^a   Zaboronok, A ^a   Ishikawa, E ^a   Aiyama, H ^a   Endo, K ^a   Takada, T ^a   Yoshida, F ^a   Shibata, Y ^a   Matsumura, A ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Chemotherapy; Glioma; Radiation; Temozolomide; X ray

Indexed keywords

BORON NEUTRON CAPTURE THERAPY; END POINTS; GLIOMA; OVERALL SURVIVAL; PHASE II; TEMOZOLOMIDE; X RAY IRRADIATION;

BORON; BORON COMPOUNDS; CHEMOTHERAPY; TUMORS; X RAYS;

NEUTRON IRRADIATION;

4 BORONOPHENYLALANINE; BOROCAPTATE; CARBON 11; FLUORINE 18; TEMOZOLOMIDE;

ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER SURVIVAL; CLINICAL EFFECTIVENESS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG SAFETY; DRUG UPTAKE; ERYTHEMA; GLIOBLASTOMA; HUMAN; MULTIPLE CYCLE TREATMENT; NEUTRON CAPTURE THERAPY; ORBIT TUMOR; OVERALL SURVIVAL; PHASE 2 CLINICAL TRIAL; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIATION DOSE; X IRRADIATION;

ANTINEOPLASTIC AGENTS; BORON NEUTRON CAPTURE THERAPY; COMBINED MODALITY THERAPY; DACARBAZINE; HUMANS; POSITRON-EMISSION TOMOGRAPHY;

EID: 80055069979     PISSN: 09698043     EISSN: 18729800     Source Type: Journal    
DOI: 10.1016/j.apradiso.2011.02.013     Document Type: Article

References (4)

1. Diaz A. Assessment of the results from the phase I/II boron neutron capture therapy trials at the Brookhaven National Laboratory from a clinician's point of view. J. Neurooncol. 2003, 62:101-109.
2. Nariai T., Ishiwata K., Kimura Y., et al. PET pharmacokinetic analysis to estimate boron concentration in tumor and brain as a guide to plan BNCT for malignant cerebral glioma. Appl. Radiat. Isot. 2009, 67:348-350.
3. Stupp R., Mason W.P., van den Bent M.J., et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 2005, 352:987-996.
4. Yamamoto T., Nakai K., Kageji T., et al. Boron neutron capture therapy for newly diagnosed glioblastoma. Radiother. Oncol. 2009, 91(80-84):73.