Keeping the clocks ticking as we age: Changes in sinoatrial node gene expression and function in the ageing heart

Experimental Physiology

Volumn 96, Issue 11, 2011, Pages 1114-1115

  Rose, Robert A ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CALCIUM ION; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; MESSENGER RNA; RYANODINE RECEPTOR 2;

AGING; BIOLOGICAL RHYTHM; ELECTROPHYSIOLOGY; GENE EXPRESSION; GENE FUNCTION; HEART ARRHYTHMIA; HUMAN; IMMUNOHISTOCHEMISTRY; NOTE; SARCOPLASMIC RETICULUM; SICK SINUS SYNDROME; SINUS NODE;

EID: 80055047274     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2011.060418     Document Type: Note

References (5)

1. de Marneffe M, Gregoire JM, Waterschoot P & Kestemont MP (1993). The sinus node function: normal and pathological. Eur Heart J 14, 649-654.
2. Dobrzynski H, Boyett MR & Anderson RH (2007). New insights into pacemaker activity: promoting understanding of sick sinus syndrome. Circulation 115, 1921-1932.
3. 2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker. Circ Res 106, 659-673.
4. Mangoni ME & Nargeot J (2008). Genesis and regulation of the heart automaticity. Physiol Rev 88, 919-982.
5. 2+ clock genes underlying sino-atrial node pacemaking. Exp Physiol 96, 1163-1178.