S-diclofenac protects against doxorubicin-induced cardiomyopathy in mice via ameliorating cardiac gap junction remodeling

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Zhang, Huili ^a   Zhang, Alian ^a   Guo, Changfa ^b   Shi, Chunzhi ^a   Zhang, Yang ^a   Liu, Qing ^a   Sparatore, Anna ^c   Wang, Changqian ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b FUDAN UNIVERSITY   (China)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 40; CONNEXIN 43; CONNEXIN 45; CREATINE KINASE; CYSTATHIONINE GAMMA LYASE; DICLOFENAC; DOXORUBICIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYDROGEN SULFIDE; LACTATE DEHYDROGENASE; MALONALDEHYDE; MYELOPEROXIDASE; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; 2 ((2,6 DICHLOROPHENYL)AMINO)BENZENEACETIC ACID 4 (3H 1,2 DITHIOL 3 THIONE 5 YL)PHENYL ESTER; 2-((2,6-DICHLOROPHENYL)AMINO)BENZENEACETIC ACID 4-(3H-1,2-DITHIOL-3-THIONE-5-YL)PHENYL ESTER; ANTINEOPLASTIC ANTIBIOTIC; DRUG DERIVATIVE; THIOKETONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG DOSE COMPARISON; GAP JUNCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FUNCTION; HEART PROTECTION; MALE; MOUSE; NONHUMAN; SURVIVAL RATE; ANIMAL; CELL JUNCTION; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; HEART; OXIDATIVE STRESS; PATHOPHYSIOLOGY;

MAMMALIA; MURINAE; MUS;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CARDIOMYOPATHIES; DICLOFENAC; DOWN-REGULATION; DOXORUBICIN; GAP JUNCTIONS; HEART; MICE; OXIDATIVE STRESS; THIONES;

EID: 80055040232     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026441     Document Type: Article

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