Enzymatic synthesis of l-tert-leucine with branched chain aminotransferase

Journal of Microbiology and Biotechnology

Volumn 21, Issue 10, 2011, Pages 1049-1052

  Seo, Young Man ^a   Yun, Hyungdon ^a  

^a Yeungnam University   (South Korea)

Author keywords

Aminotransferase; Branched chain aminotransferase; Coupling reaction; L tert leucine; Unnatural amino acid

Indexed keywords

2 OXOGLUTARIC ACID; AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BRANCHED CHAIN AMINOTRANSFERASE; GLUTAMIC ACID; LEUCINE; LEVO TERT LEUCINE; PYRUVATE DECARBOXYLASE; PYRUVIC ACID DERIVATIVE; TRIMETHYLPYRUVATE; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; AMINO ACID SYNTHESIS; ARTICLE; BIOTRANSFORMATION; CATALYSIS; CHEMICAL INTERACTION; CHEMICAL MODIFICATION; CONTROLLED STUDY; CROSS COUPLING REACTION; ENZYME ACTIVITY; ESCHERICHIA COLI; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN;

ASPARTATE AMINOTRANSFERASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GLUTAMIC ACID; LEUCINE; PYRUVATE DECARBOXYLASE; TRANSAMINASES;

ESCHERICHIA COLI;

EID: 80055031641     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: 10.4014/jmb.1105.05049     Document Type: Article

References (16)

1. Allenmark, S. and B. Lamm. 2001. A useful route to (R)-and (S)-tert-leucine. Chirality 13: 43-47.
2. Bea, H. S., H. J. Park, S. H. Lee, and H. Yun. 2011. Kinetic resolution of aromatic β-amino acids by ω-transaminase. Chem. Commun. 47: 5894-5896.
3. Bommarius, A. S., M. Schwarm, and K. Drauz. 1998. Biocatalysis to amino acid-based chiral pharmaceuticals -examples and perspectives. J. Mol. Catal. B Enzym. 5: 1-11.
4. Hwang, B. Y., B. K. Cho, H. Yun, K. Koteshwar, and B. G. Kim. 2005. Revisit of aminotransferase in the genomic era and its application to biocatalysis. J. Mol. Catal. B Enzym. 37: 47-55.
5. Hong, E. Y., M. Cha, H. Yun, and B. G. Kim. 2010. Asymmetric synthesis of L-tert-leucine and L-3-hydroxyadamantylglycine using branched chain aminotransferase. J. Mol. Catal. B Enzym. 66: 228-233.
6. Li, T., A. B. Kootstra, and I. G. Fotheringham. 2002. Nonproteinogenic α-amino acid preparation using equilibrium shifted transamination. Org. Proc. Res. Dev. 6: 533-538.
7. Liu, S. L., Q. X. Song, D. Z. Wei, Y. W. Zhang, and X. D. Wang. 2006. Preparation of optically pure tert-leucine by penicillin G acylase-catalyzed resolution. Prep. Biochem. Biotech. 36: 235-241.
8. Liu, S. L., D. Z. Wei, Q. X. Song, Y. W. Zhang, and X. D. Wang. 2006. Effect of organic cosolvent on kinetic resolution of tert-leucine by penicillin G acylase from Kluyvera citrophila. Bioproc. Biosyst. Eng. 28: 285-289.
9. Ma, J. A. 2003. Recent developments in the catalytic asymmetric synthesis of α-and β-amino acids. Angew. Chem. Int. Edit. 42: 4290-4299.
10. Schmidt, E., B. Bossow, R. Wichmann, and C. Wandrey. 1986. Enzyme membrane reactor -an alternative approach for continuous operation with enzymes. Kem. Ind. 35: 71-77.
11. Seo, Y. M., Y. H. Khang, and H. Yun. 2011. Kinetic resolution of 3-fluoroalanine using a fusion protein of D-amino acid oxidase with vitreoscilla hemoglobin. Biosci. Biotechnol. Biochem. 75: 820-822.
12. Steward, J. D. 2001. Dehydrogenases and transaminases in asymmetric synthesis. Curr. Opin. Chem. Biol. 5: 120-129.
13. Taylor, P. P., D. P. Pantaleone, R. F. Senkpeil, and I. G. Fotheringham. 1998. Novel biosynthetic approaches to the production of unnatural amino acids using transaminases. Trends Biotechnol. 16: 412-418.
14. Turner, N. J., J. R. Winterman, R. McCague, J. S. Parratt, and S. J. C. Taylor. 1995. Synthesis of homochiral L-(S)-tert-leucine via a lipase catalysed dynamic resolution process. Tetrahedron Lett. 36: 1113-1136.
15. Yun, H. and B. G. Kim. 2008. Enzymatic production of (R)-phenylacetylcarbinol by pyruvate decarboxylase from Zymomonas mobilis. Biotechnol. Bioprocess Eng. 13: 372-376.
16. Zhu, D. and L. Hua. 2009. Biocatalytic asymmetric amination of carbonyl functional groups -a synthetic biology approach to organic chemistry. Biotechnol. J. 4: 1420-1431.