메뉴 건너뛰기




Volumn 26, Issue 11, 2011, Pages 2672-2681

The pathophysiology of early-stage chronic kidney disease-mineral bone disorder (CKD-MBD) and response to phosphate binders in the rat

Author keywords

Bone; CKD MBD; FGF23; Intestine; Kidney; Mineral; Parathyroid hormone; Phosphorus

Indexed keywords

CALCITRIOL; CALCIUM CARBONATE; FIBROBLAST GROWTH FACTOR 23; KLOTHO PROTEIN; MESSENGER RNA; PARATHYROID HORMONE; SEVELAMER CARBONATE; TRANSCRIPTION FACTOR RUNX2;

EID: 80055024312     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.485     Document Type: Article
Times cited : (82)

References (42)
  • 1
    • 33645757920 scopus 로고    scopus 로고
    • Definition, evaluation, and classification of renal osteodystrophy: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO)
    • DOI 10.1038/sj.ki.5000414, PII 5000414
    • Moe S, Drueke T, Cunningham J, Goodman W, Martin K, Olgaard K, Ott S, Sprague S, Lameire N, Eknoyan G,. Definition, evaluation, and classification of renal osteodystrophy: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int. 2006; 69 (11): 1945-53. (Pubitemid 43924257)
    • (2006) Kidney International , vol.69 , Issue.11 , pp. 1945-1953
    • Moe, S.1    Drueke, T.2    Cunningham, J.3    Goodman, W.4    Martin, K.5    Olgaard, K.6    Ott, S.7    Sprague, S.8    Lameire, N.9    Eknoyan, G.10
  • 4
    • 33845700085 scopus 로고    scopus 로고
    • Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: Results of the study to evaluate early kidney disease
    • DOI 10.1038/sj.ki.5002009, PII 5002009
    • Levin A, Bakris GL, Molitch M, Smulders M, Tian J, Williams LA, Andress DL,., Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: results of the study to evaluate early kidney disease. Kidney Int. 2007; 71 (1): 31-8. (Pubitemid 44967731)
    • (2007) Kidney International , vol.71 , Issue.1 , pp. 31-38
    • Levin, A.1    Bakris, G.L.2    Molitch, M.3    Smulders, M.4    Tian, J.5    Williams, L.A.6    Andress, D.L.7
  • 6
    • 83055172414 scopus 로고    scopus 로고
    • Clinical practice guidelines for bone metabolism and disease in chronic kidney disease
    • K/DOQI NKF
    • K/DOQI NKF. Clinical practice guidelines for bone metabolism and disease in chronic kidney disease. Am J Kidney Dis. 2003; 42 (Supplement): S1-S201.
    • (2003) Am J Kidney Dis. , vol.42 , Issue.SUPPLEMENT
  • 7
    • 70349359435 scopus 로고    scopus 로고
    • Clinical practice guidelines for the management of CKD-MBD
    • KDIGO
    • KDIGO. Clinical practice guidelines for the management of CKD-MBD. Kidney Int. 2009; 76 (S113): S1-S130.
    • (2009) Kidney Int. , vol.76 , Issue.S113
  • 9
    • 0025916406 scopus 로고
    • Hereditary polycystic kidney disease. Adult polycystic kidney disease associated with renal hypertension, renal osteodystrophy, and uremic enteritis in SPRD rats
    • Kaspareit-Rittinghausen J, Deerberg F, Wcislo A,. Hereditary polycystic kidney disease. Adult polycystic kidney disease associated with renal hypertension, renal osteodystrophy, and uremic enteritis in SPRD rats. Am J Pathol. 1991; 139 (3): 693-6.
    • (1991) Am J Pathol. , vol.139 , Issue.3 , pp. 693-696
    • Kaspareit-Rittinghausen, J.1    Deerberg, F.2    Wcislo, A.3
  • 13
    • 12644271201 scopus 로고    scopus 로고
    • Gender and the effect of gonadal hormones on the progression of inherited polycystic kidney disease in rats
    • Cowley BD Jr, Rupp JC, Muessel MJ, Gattone VH 2nd., Gender and the effect of gonadal hormones on the progression of inherited polycystic kidney disease in rats. Am J Kidney Dis. 1997; 29 (2): 265-72. (Pubitemid 27130738)
    • (1997) American Journal of Kidney Diseases , vol.29 , Issue.2 , pp. 265-272
    • Cowley Jr., B.D.1    Rupp, J.C.2    Muessel, M.J.3    Gattone II, V.H.4
  • 15
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD,. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001; 25 (4): 402-8. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 16
    • 0032930729 scopus 로고    scopus 로고
    • Marked osteoblastopenia and reduced bone formation in a model of multiple myeloma bone disease in severe combined immunodeficiency mice
    • DOI 10.1359/jbmr.1999.14.2.256
    • Hjorth-Hansen H, Seifert MF, Borset M, Aarset H, Ostlie A, Sundan A, Waage A,. Marked osteoblastopenia and reduced bone formation in a model of multiple myeloma bone disease in severe combined immunodeficiency mice. J Bone Miner Res. 1999; 14 (2): 256-63. (Pubitemid 29066251)
    • (1999) Journal of Bone and Mineral Research , vol.14 , Issue.2 , pp. 256-263
    • Hjorth-Hansen, H.1    Seifert, M.F.2    Borset, M.3    Aarset, H.4    Ostlie, A.5    Sundan, A.6    Waage, A.7
  • 17
    • 0023488581 scopus 로고
    • Bone histomorphometry: Standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee
    • Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Recker RR,. Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res. 1987; 2 (6): 595-610.
    • (1987) J Bone Miner Res. , vol.2 , Issue.6 , pp. 595-610
    • Parfitt, A.M.1    Drezner, M.K.2    Glorieux, F.H.3    Kanis, J.A.4    Malluche, H.5    Meunier, P.J.6    Ott, S.M.7    Recker, R.R.8
  • 18
    • 0142187235 scopus 로고    scopus 로고
    • Sevelamer hydrochloride attenuates kidney and cardiovascular calcifications in long-term experimental uremia
    • DOI 10.1046/j.1523-1755.2003.00284.x
    • Cozzolino M, Staniforth ME, Liapis H, Finch J, Burke SK, Dusso AS, Slatopolsky E,. Sevelamer hydrochloride attenuates kidney and cardiovascular calcifications in long-term experimental uremia. Kidney Int. 2003; 64 (5): 1653-61. (Pubitemid 37323693)
    • (2003) Kidney International , vol.64 , Issue.5 , pp. 1653-1661
    • Cozzolino, M.1    Staniforth, M.E.2    Liapis, H.3    Finch, J.4    Burke, S.K.5    Dusso, A.S.6    Slatopolsky, E.7
  • 19
    • 31544450766 scopus 로고    scopus 로고
    • Effect of manipulating serum phosphorus with phosphate binder on circulating PTH and FGF23 in renal failure rats
    • DOI 10.1038/sj.ki.5000020, PII 5000020
    • Nagano N, Miyata S, Abe M, Kobayashi N, Wakita S, Yamashita T, Wada M,. Effect of manipulating serum phosphorus with phosphate binder on circulating PTH and FGF23 in renal failure rats. Kidney Int. 2006; 69 (3): 531-7. (Pubitemid 43164446)
    • (2006) Kidney International , vol.69 , Issue.3 , pp. 531-537
    • Nagano, N.1    Miyata, S.2    Abe, M.3    Kobayashi, N.4    Wakita, S.5    Yamashita, T.6    Wada, M.7
  • 20
    • 0022449729 scopus 로고
    • Animal model of adenine-induced chronic renal failure in rats
    • Yokozawa T, Zheng PD, Oura H, Koizumi F,. Animal model of adenine-induced chronic renal failure in rats. Nephron. 1986; 44 (3): 230-4. (Pubitemid 16002549)
    • (1986) Nephron , vol.44 , Issue.3 , pp. 230-234
    • Yokozawa, T.1    Zheng, P.D.2    Oura, H.3    Koizumi, F.4
  • 21
    • 61349180704 scopus 로고    scopus 로고
    • Effect of bisphosphonates on vascular calcification and bone metabolism in experimental renal failure
    • Lomashvili KA, Monier-Faugere MC, Wang X, Malluche HH, O'Neill WC,. Effect of bisphosphonates on vascular calcification and bone metabolism in experimental renal failure. Kidney Int. 2009; 75 (6): 617-25.
    • (2009) Kidney Int. , vol.75 , Issue.6 , pp. 617-625
    • Lomashvili, K.A.1    Monier-Faugere, M.C.2    Wang, X.3    Malluche, H.H.4    O'Neill, W.C.5
  • 22
    • 33644857657 scopus 로고    scopus 로고
    • Sevelamer hydrochloride reverses parathyroid gland enlargement via regression of cell hypertrophy but not apoptosis in rats with chronic renal insufficiency
    • DOI 10.1093/ndt/gfi137
    • Nagano N, Miyata S, Abe M, Wakita S, Kobayashi N, Wada M,. Sevelamer hydrochloride reverses parathyroid gland enlargement via regression of cell hypertrophy but not apoptosis in rats with chronic renal insufficiency. Nephrol Dial Transplant. 2006; 21 (3): 634-43. (Pubitemid 43372908)
    • (2006) Nephrology Dialysis Transplantation , vol.21 , Issue.3 , pp. 634-643
    • Nagano, N.1    Miyata, S.2    Abe, M.3    Wakita, S.4    Kobayashi, N.5    Wada, M.6
  • 24
    • 64049103456 scopus 로고    scopus 로고
    • Lanthanum carbonate reduces phosphorus burden in patients with CKD stages 3 and 4: A randomized trial
    • Sprague SM, Abboud H, Qiu P, Dauphin M, Zhang P, Finn W,. Lanthanum carbonate reduces phosphorus burden in patients with CKD stages 3 and 4: a randomized trial. Clin J Am Soc Nephrol. 2009; 4 (1): 178-85.
    • (2009) Clin J Am Soc Nephrol. , vol.4 , Issue.1 , pp. 178-185
    • Sprague, S.M.1    Abboud, H.2    Qiu, P.3    Dauphin, M.4    Zhang, P.5    Finn, W.6
  • 25
    • 2942692214 scopus 로고    scopus 로고
    • Effect of 2′-phosphophloretin on renal function in chronic renal failure rats
    • DOI 10.1152/ajprenal.00360.2003
    • Peerce BE, Weaver L, Clarke RD,. Effect of 2'-phosphophloretin on renal function in chronic renal failure rats. Am J Physiol Renal Physiol. 2004; 287 (1): F48-56. (Pubitemid 38780582)
    • (2004) American Journal of Physiology - Renal Physiology , vol.287 , Issue.1
    • Peerce, B.E.1    Weaver, L.2    Clarke, R.D.3
  • 27
    • 0027620203 scopus 로고
    • Renal and intestinal Pi transport adaptation to low phosphorus diet in uremic rats
    • Loghman-Adham M,. Renal and intestinal Pi transport adaptation to low phosphorus diet in uremic rats. J Am Soc Nephrol. 1993; 3 (12): 1930-7.
    • (1993) J Am Soc Nephrol. , vol.3 , Issue.12 , pp. 1930-1937
    • Loghman-Adham, M.1
  • 28
    • 29144527562 scopus 로고    scopus 로고
    • Inhibition of intestinal sodium-dependent inorganic phosphate transport by fibroblast growth factor 23
    • Miyamoto K, Ito M, Kuwahata M, Kato S, Segawa H,. Inhibition of intestinal sodium-dependent inorganic phosphate transport by fibroblast growth factor 23. Ther Apher Dial. 2005; 9 (4): 331-5. (Pubitemid 41800804)
    • (2005) Therapeutic Apheresis and Dialysis , vol.9 , Issue.4 , pp. 331-335
    • Miyamoto, K.-I.1    Ito, M.2    Kuwahata, M.3    Kato, S.4    Segawa, H.5
  • 29
    • 57149108326 scopus 로고    scopus 로고
    • Matrix extracellular phosphoglycoprotein inhibits phosphate transport
    • Marks J, Churchill LJ, Debnam ES, Unwin RJ,. Matrix extracellular phosphoglycoprotein inhibits phosphate transport. J Am Soc Nephrol. 2008; 19 (12): 2313-20.
    • (2008) J Am Soc Nephrol. , vol.19 , Issue.12 , pp. 2313-2320
    • Marks, J.1    Churchill, L.J.2    Debnam, E.S.3    Unwin, R.J.4
  • 30
    • 77955362086 scopus 로고    scopus 로고
    • Phosphate homeostasis and the renal-gastrointestinal axis
    • Marks J, Debnam ES, Unwin RJ,. Phosphate homeostasis and the renal-gastrointestinal axis. Am J Physiol Renal Physiol. 2010; 299 (2): F285-96.
    • (2010) Am J Physiol Renal Physiol. , vol.299 , Issue.2
    • Marks, J.1    Debnam, E.S.2    Unwin, R.J.3
  • 34
    • 77955625789 scopus 로고    scopus 로고
    • 1alpha,25-dihydroxyvitamin D3 acts predominately in mature osteoblasts under conditions of high extracellular phosphate to increase fibroblast growth factor 23 production in vitro
    • Yamamoto R, Minamizaki T, Yoshiko Y, Yoshioka H, Tanne K, Aubin JE, Maeda N,. 1alpha,25-dihydroxyvitamin D3 acts predominately in mature osteoblasts under conditions of high extracellular phosphate to increase fibroblast growth factor 23 production in vitro. J Endocrinol. 2010; 206 (3): 279-86.
    • (2010) J Endocrinol. , vol.206 , Issue.3 , pp. 279-286
    • Yamamoto, R.1    Minamizaki, T.2    Yoshiko, Y.3    Yoshioka, H.4    Tanne, K.5    Aubin, J.E.6    Maeda, N.7
  • 35
    • 77957993384 scopus 로고    scopus 로고
    • PTH increases FGF23 gene expression and mediates the high FGF23 levels of experimental kidney failure: A bone parathyroid feedback loop
    • Lavi-Moshayoff V, Wasserman G, Meir T, Silver J, Naveh-Many T,. PTH increases FGF23 gene expression and mediates the high FGF23 levels of experimental kidney failure: a bone parathyroid feedback loop. Am J Physiol Renal Physiol. 2010; 299 (4): F882-9.
    • (2010) Am J Physiol Renal Physiol. , vol.299 , Issue.4
    • Lavi-Moshayoff, V.1    Wasserman, G.2    Meir, T.3    Silver, J.4    Naveh-Many, T.5
  • 39
    • 0031885412 scopus 로고    scopus 로고
    • NPS R-568 halts or reverses osteitis fibrosa in uremic rats
    • DOI 10.1046/j.1523-1755.1998.00782.x
    • Wada M, Ishii H, Furuya Y, Fox J, Nemeth EF, Nagano N,. NPS R-568 halts or reverses osteitis fibrosa in uremic rats. Kidney Int. 1998; 53 (2): 448-53. (Pubitemid 28097862)
    • (1998) Kidney International , vol.53 , Issue.2 , pp. 448-453
    • Wada, M.1    Ishii, H.2    Furuya, Y.3    Fox, J.4    Nemeth, E.F.5    Nagano, N.6
  • 41
    • 50849132537 scopus 로고    scopus 로고
    • Chronic kidney disease and bone fracture: A growing concern
    • Nickolas TL, Leonard MB, Shane E,. Chronic kidney disease and bone fracture: a growing concern. Kidney Int. 2008; 74 (6): 721-31.
    • (2008) Kidney Int. , vol.74 , Issue.6 , pp. 721-731
    • Nickolas, T.L.1    Leonard, M.B.2    Shane, E.3
  • 42
    • 0346849707 scopus 로고    scopus 로고
    • Klotho, a Gene Related to a Syndrome Resembling Human Premature Aging, Functions in a Negative Regulatory Circuit of Vitamin D Endocrine System
    • DOI 10.1210/me.2003-0048
    • Tsujikawa H, Kurotaki Y, Fujimori T, Fukuda K, Nabeshima Y,. Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system. Mol Endocrinol. 2003; 17 (12): 2393-403. (Pubitemid 37542205)
    • (2003) Molecular Endocrinology , vol.17 , Issue.12 , pp. 2393-2403
    • Tsujikawa, H.1    Kurotaki, Y.2    Fujimori, T.3    Fukuda, K.4    Nabeshima, Y.-I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.