Modulation of integrin α4β1 by ADAM28 promotes lymphocyte adhesion and transendothelial migration

Cell Biology International

Volumn 35, Issue 10, 2011, Pages 1043-1053

  McGinn, Owen J ^a   English, William R ^a   Roberts, Stephanie ^b   Ager, Ann ^c   Newham, Peter ^b   Murphy, Gillian ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

^c CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

A disintegrin and metalloproteinase (ADAM); B lymphocyte; Cell migration; Integrin; Vascular cell adhesion molecule (VCAM)

Indexed keywords

A DISINTEGRIN AND METALLOPROTEINASE 28; ADAM PROTEIN; MANGANESE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 9EG7; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ACTIVATION ANTIGEN 4;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; B CELL LYMPHOMA; B LYMPHOCYTE; CELL ADHESION; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BINDING; HUMAN; HUMAN CELL; HUMAN TISSUE; LEUKEMIA CELL; LYMPHOCYTE; LYMPHOMA CELL LINE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION;

ADAM PROTEINS; ANIMALS; ANTIBODIES, MONOCLONAL; B-LYMPHOCYTES; CELL ADHESION; CELL LINEAGE; CERCOPITHECUS AETHIOPS; COS CELLS; HUMANS; INTEGRIN ALPHA4BETA1; MANGANESE; MICE; RECOMBINANT PROTEINS; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; VASCULAR CELL ADHESION MOLECULE-1;

MURINAE;

EID: 80055012497     PISSN: 10656995     EISSN: 10958355     Source Type: Journal    
DOI: 10.1042/CBI20100885     Document Type: Article

References (52)

1. Alon R, Kassner PD, Carr MW, Finger EB, Hemler ME, Springer TA. The integrin VLA-4 supports tethering and rolling in flow on VCAM-1. J Cell Biol 1995;128:1243-53.
2. Altevogt P, Hubbe M, Ruppert M, Lohr J, von Hoegen P, Sammar M et al. The alpha 4 integrin chain is a ligand for alpha 4 beta 7 and alpha 4 beta 1. J Exp Med 1995;182:345-55.
3. Andrew DP, Berlin C, Honda S, Yoshino T, Hamann A, Holzmann B et al. Distinct but overlapping epitopes are involved in alpha 4 beta 7-mediated adhesion to vascular cell adhesion molecule-1, mucosal addressin-1, fibronectin, and lymphocyte aggregation. J Immunol 1994;153:3847-61.
4. Andrew DP, Yoshino T, Guh L, Martin-Simonet MT, Butcher EC. TABS, a T cell activation antigen that induces LFA-1-dependent aggregation. J Immunol 1995;155:1671-84.
5. Barry ST, Ludbrook SB, Murrison E, Horgan CM. Analysis of the alpha4beta1 integrin-osteopontin interaction. Exp Cell Res 2000;258:342-51.
6. Bayless KJ, Meininger GA, Scholtz JM, Davis GE. Osteopontin is a ligand for the alpha4beta1 integrin. J Cell Sci 1998;111:1165-74.
7. Bazzoni G, Shih DT, Buck CA, Hemler ME. Monoclonal antibody 9EG7 defines a novel beta 1 integrin epitope induced by soluble ligand and manganese, but inhibited by calcium. J Biol Chem 1995;270:25570-7.
8. Black RA, White JM. ADAMs: focus on the protease domain. Curr Opin Cell Biol 1998;10:654-9.
9. Blobel CP. Metalloprotease-disintegrins: links to cell adhesion and cleavage of TNF alpha and Notch. Cell 1997;90:589-92.
10. Bridges LC, Tani PH, Hanson KR, Roberts CM, Judkins MB, Bowditch RD. The lymphocyte metalloprotease MDC-L (ADAM 28) is a ligand for the integrin alpha4beta1. J Biol Chem 2002;277:3784-92.
11. Bridges LC, Hanson KR, Tani PH, Mather T, Bowditch RD. Integrin alpha4beta1-dependent adhesion to ADAM 28 (MDC-L) requires an extended surface of the disintegrin domain. Biochemistry 2003;42:3734-41.
12. Bridges LC, Sheppard D, Bowditch RD. ADAM disintegrin-like domain recognition by the lymphocyte integrins alpha4beta1 and alpha4beta7. Biochem J 2005;387:101-8.
13. Bridges LC, Lingo JD, Grandon RA, Kelley MD. All-trans-retinoic acid induces integrin-independent B-cell adhesion to ADAM disintegrin domains. Biochemistry 2008;47:4544-51.
14. Carrasco YR, Batista FD. B-cell activation by membrane-bound antigens is facilitated by the interaction of VLA-4 with VCAM-1. EMBO J 2006;25:889-99.
15. Chigaev A, Blenc AM, Braaten JV, Kumaraswamy N, Kepley CL, Andrews RP et al. Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn2+ or antibody activation. J Biol Chem 2001;276:48670-8.
16. Deisher TA, Haddix TL, Montgomery KF, Pohlman TH, Kaushansky K, Harlan JM. The role of protein kinase C in the induction of VCAM-1 expression on human umbilical vein endothelial cells. FEBS Lett 1993;331:285-90.
17. Edwards DR, Handsley MM, Pennington CJ. The ADAM metalloproteinases. Mol Aspects Med 2008;29:258-89.
18. Elices MJ, Osborn L, Takada Y, Crouse C, Luhowskyj S, Hemler ME, et al. VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site. Cell 1990;60:577-84.
19. Haidl ID, Huber G, Eichmann K. An ADAM family member with expression in thymic epithelial cells and related tissues. Gene 2002;283:163-70.
20. Howard L, Maciewicz RA, Blobel CP. Cloning and characterization of ADAM28: evidence for autocatalytic pro-domain removal and for cell surface localization of mature ADAM28. Biochem J 2000;348:21-7.
21. Howard L, Zheng Y, Horrocks M, Maciewicz RA, Blobel C. Catalytic activity of ADAM28. FEBS Lett 2001;498:82-6.
22. Humphries JD, Byron A, Humphries MJ. Integrin ligands at a glance. J Cell Sci 2006;119:3901-3.
23. Hynes RO. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 1992;69:11-25.
24. Hyun YM, Chung HL, McGrath JL, Waugh RE, Kim M. Activated integrin VLA-4 localizes to the lamellipodia and mediates T cell migration on VCAM-1. J Immunol 2009;183:359-69.
25. Iademarco MF, Barks JL, Dean DC. Regulation of vascular cell adhesion molecule-1 expression by IL-4 and TNFalpha in cultured endothelial cells. J Clin Invest 1995;95:264-71.
26. Jakubowski A, Ehrenfels BN, Pepinsky RB, Burkly LC. Vascular cell adhesion molecule-Ig fusion protein selectively targets activated alpha 4-integrin receptors in vivo. Inhibition of autoimmune diabetes in an adoptive transfer model in nonobese diabetic mice. J Immunol 1995;155:938-46.
27. Johnston SC, Dustin ML, Hibbs ML, Springer TA. On the species specificity of the interaction of LFA-1 with intercellular adhesion molecules. J Immunol 1990;145:1181-7.
28. Li Z, Calzada MJ, Sipes JM, Cashel JA, Krutzsch HC, Annis DS et al. Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior. J Cell Biol 2002;157:509-19.
29. Lo CG, Lu TT, Cyster JG. Integrin-dependence of lymphocyte entry into the splenic white pulp. J Exp Med 2003;197:353-61.
30. Lu TT, Cyster JG. Integrin-mediated long-term B cell retention in the splenic marginal zone. Science 2002;297:409-12.
31. Matheny HE, Deem TL, Cook-Mills JM. Lymphocyte migration through monolayers of endothelial cell lines involves VCAM-1 signaling via endothelial cell NADPH oxidase. J Immunol. 2000;164:6550-9.
32. May MJ, Entwistle G, Humphries MJ, Ager A. VCAM-1 is a CS1 peptideinhibitable adhesion molecule expressed by lymph node high endothelium. J Cell Sci 1993;106:109-19.
33. McEver RP, Cummings RD. Perspectives series: cell adhesion in vascular biology. Role of PSGL-1 binding to selectins in leukocyte recruitment. J Clin Invest 1997;100:485-91.
34. Mitsui Y, Mochizuki S, Kodama T, Shimoda M, Ohtsuka T, Shiomi T et al. ADAM28 is overexpressed in human breast carcinomas:implications for carcinoma cell proliferation through cleavage of insulin-like growth factor binding protein-3. Cancer Res 2006;66:9913-20.
35. Moore KL, Patel KD, Bruehl RE, Li F, Johnson DA, Lichenstein HS et al. P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin. J Cell Biol 1995;128:661-71.
36. Mould AP, Wheldon LA, Komoriya A, Wayner EA, Yamada KM, Humphries MJ. Affinity chromatographic isolation of the melanoma adhesion receptor for the IIICS region of fibronectin and its identification as the integrin alpha 4 beta 1. J Biol Chem 1990;265:4020-4.
37. Neish AS, Williams AJ, Palmer HJ, Whitley MZ, Collins T. Functional analysis of the human vascular cell adhesion molecule 1 promoter. J Exp Med 1992;176:1583-93.
38. Ohtsuka T, Shiomi T, Shimoda M, Kodama T, Amour A, Murphy G et al. ADAM28 is overexpressed in human non-small cell lung carcinomas and correlates with cell proliferation and lymph node metastasis. Int J Cancer 2006;118:263-73.
39. Primakoff P, Myles DG. The ADAM gene family: surface proteins with adhesion and protease activity. Trends Genet 2000;16:83-7.
40. Puxeddu I, Pang YY, Harvey A, Haitchi HM, Nicholas B, Yoshisue H et al. The soluble form of a disintegrin and metalloproteinase 33 promotes angiogenesis: implications for airway remodeling in asthma. J Allergy Clin Immunol 2008;121:1400-6.
41. Redondo-Munoz J, Escobar-Diaz E, Samaniego R, Terol MJ, Garcia-Marco JA, Garcia-Pardo A. MMP-9 in B-cell chronic lymphocytic leukemia is up-regulated by alpha4beta1 integrin or CXCR4 engagement via distinct signaling pathways, localizes to podosomes, and is involved in cell invasion and migration. Blood 2006;108:3143-51.
42. Roberts CM, Tani PH, Bridges LC, Laszik Z, Bowditch RD, MDC-L, a novel metalloprotease disintegrin cysteine-rich protein family member expressed by human lymphocytes. J Biol Chem 1999;274:29251-9.
43. Rose DM, Han J, Ginsberg MH. Alpha4 integrins and the immune response. Immunol Rev 2002;186:118-24.
44. Schlondorff J, Blobel CP. Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding. J Cell Sci 1999;112:3603-17.
45. Seals DF, Courtneidge SA. The ADAMs family of metalloproteases: multidomain proteins with multiple functions. Genes Dev 2003;17:7-30.
46. Sheppard D. In vivo functions of integrins: lessons from null mutations in mice. Matrix Biol 2000;19:203-9.
47. Shimoda M, Hashimoto G, Mochizuki S, Ikeda E, Nagai N, Ishida S, et al. Binding of ADAM28 to P-selectin glycoprotein ligand-1 enhances P-selectin-mediated leukocyte adhesion to endothelial cells. J Biol Chem 2007;282:25864-74.
48. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 1994;76:301-14.
49. Strauch UG, Lifka A, Gosslar U, Kilshaw PJ, Clements J, Holzmann B. Distinct binding specificities of integrins alpha 4 beta 7 (LPAM-1), alpha 4 beta 1 (VLA-4), and alpha IEL beta 7. Int Immunol 1994;6:263-75.
50. Takeda S, Igarashi T, Mori H, Araki S. Crystal structures of VAP1 reveal ADAMs' MDC domain architecture and its unique C-shaped scaffold. EMBO J 2006;25:2388-96.
51. Till KJ, Lin K, Zuzel M, Cawley JC. The chemokine receptor CCR7 and alpha4 integrin are important for migration of chronic lymphocytic leukemia cells into lymph nodes. Blood 2002;99:2977-84.
52. Wayner EA, Garcia-Pardo A, Humphries MJ, McDonald JA, Carter WG. Identification and characterization of the T lymphocyte adhesion receptor for an alternative cell attachment domain (CS-1) in plasma fibronectin. J Cell Biol 1989;109:1321-30.