Sinutriangulin A, a novel diterpenoid from the soft coral Sinularia triangula

Tetrahedron Letters

Volumn 52, Issue 44, 2011, Pages 5869-5871

  Lu, Mei Chin ^a,b   Lee, Nai Lun ^b   Tseng, Shang Wei ^b   Su, Jui Hsin ^a,b,c  

^a NATIONAL MUSEUM OF MARINE BIOLOGY AND AQUARIUM   (Taiwan)

^b NATIONAL DONG HWA UNIVERSITY   (Taiwan)

^c NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

Cubitane; Cytotoxicity; Sinularia triangula

Indexed keywords

DITERPENOID; SINUTRIANGULIN A; UNCLASSIFIED DRUG;

ARTICLE; CORAL; CYTOTOXICITY; DRUG ACTIVITY; DRUG ISOLATION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SINULARIA TRIANGULA; TUMOR CELL LINE;

ALCYONACEA; SINULARIA;

EID: 80055007386     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2011.08.161     Document Type: Article

References (7)

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7. Sinutriangulin A (1): Colorless oil; [α]24 D -36.0 (c 0.1, CHCl3); IR (neat) vmax 3461, 2959, 2925, 2868, 1383 and 1244 cm-1; 13C and 1H NMR data, see Table 1; selected 1H NMR (pyridine-d5, 400 MHz) dH: 6.13 (1H, br s, 11-OH), 5.88 (1H, d, J = 8.0 Hz, H-9), 3.65 (1H, d, J = 7.0 Hz, H-10), 2.80 (1H, m, H-19a), 2.80 (1H, m, H-15), 2.65 (1H, d, J = 10.0 Hz, H-4), 1.09 (3H, d, J = 6.8 Hz, H3-16), 1.05 (3H, d, J = 6.8 Hz, H3-17), 0.90 (3H, d, J = 6.8 Hz, H3-13). ESIMS m/z 327 [M + Na]+; HRESIMS m/z 327.2298 [M + Na]+ (calcd for C20H32O2Na, 327.2300).