Reflectance confocal microscopy for the diagnosis of eosinophilic esophagitis: A pilot study conducted on biopsy specimens

Gastrointestinal Endoscopy

Volumn 74, Issue 5, 2011, Pages 992-1000

  Yoo, Hongki ^a   Kang, Dongkyun ^a   Katz, Aubrey J ^a   Lauwers, Gregory Y ^a   Nishioka, Norman S ^a   Yagi, Yukako ^a   Tanpowpong, Pornthep ^a   Namati, Jacqueline ^a   Bouma, Brett E ^a,b   Tearney, Guillermo J ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

Author keywords

3 dimensional; 3D; CLE; confocal laser endomicroscopy; EoE; eosinophilic esophagitis; H E; hematoxylin and eosin; high power field; HPF; pCLE; probe based confocal laser endomicroscopy; RCM; reflectance confocal microscopy; SD; SECM; spectrally encoded confocal microscopy; standard deviation; target to background intensity ratio; TBIR

Indexed keywords

ABSCESS; ADOLESCENT; ADULT; ARTICLE; BASAL CELL; CELL HYPERPLASIA; CHILD; CLINICAL ARTICLE; CONFOCAL MICROSCOPY; DEGRANULATION; EOSINOPHIL COUNT; EOSINOPHILIC ESOPHAGITIS; ESOPHAGUS BIOPSY; ESOPHAGUS MUCOSA; FEMALE; HISTOPATHOLOGIC SKIN REACTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INFLAMMATORY CELL; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SPECTRALLY ENCODED CONFOCAL MICROSCOPY;

ABSCESS; ADOLESCENT; ADULT; BIOPSY; CELL COUNT; CELL DEGRANULATION; CHILD; CHILD, PRESCHOOL; ENDOSCOPY, DIGESTIVE SYSTEM; EOSINOPHILIC ESOPHAGITIS; EOSINOPHILS; ESOPHAGUS; FEMALE; HUMANS; HYPERPLASIA; INFANT; MALE; MICROSCOPY, CONFOCAL; MUCOUS MEMBRANE; OBSERVER VARIATION; PILOT PROJECTS; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

EID: 80054984172     PISSN: 00165107     EISSN: 10976779     Source Type: Journal    
DOI: 10.1016/j.gie.2011.07.020     Document Type: Article

References (57)

1. M. Chehade, and H.A. Sampson Epidemiology and etiology of eosinophilc esophagitis Gastrointest Endosc Clin N Am 18 2008 33 44 viii
2. R.C. Kapel, J.K. Miller, and C. Torres Eosinophilic esophagitis: a prevalent disease in the United States that affects all age groups Gastroenterology 134 2008 1316 1321
3. G.R. Veerappan, J.L. Perry, and T.J. Duncan Prevalence of eosinophilic esophagitis in an adult population undergoing upper endoscopy: a prospective study Clin Gastroenterol Hepatol 7 2009 420 426 426 e1-2
4. C.A. Liacouras Eosinophilic esophagitis Gastroenterol Clin North Am 37 2008 989 998 xi
5. D. Atkins, R. Kramer, and K. Capocelli Eosinophilic esophagitis: the newest esophageal inflammatory disease Nat Rev Gastroenterol Hepatol 6 2009 267 278
6. G.A. Prasad, and N.J. Talley Eosinophilic esophagitis in adults Gastroenterol Clin North Am 37 2008 349 368 v-vi
7. P.E. Putnam, and M.E. Rothenberg Eosinophilic esophagitis: concepts, controversies, and evidence Curr Gastroenterol Rep 11 2009 220 225
8. G.T. Furuta, C.A. Liacouras, and M.H. Collins Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment Gastroenterology 133 2007 1342 1363
9. N. Gonsalves, M. Policarpio-Nicolas, and Q. Zhang Histopathologic variability and endoscopic correlates in adults with eosinophilic esophagitis Gastrointest Endosc 64 2006 313 319
10. M.H. Collins Histopathologic features of eosinophilic esophagitis Gastrointest Endosc Clin N Am 18 2008 59 71 viii-ix
11. M. Remedios, C. Campbell, and P.M. Jones Eosinophilic esophagitis in adults: clinical, endoscopic, histologic findings, and response to treatment with fluticasone propionate Gastrointest Endosc 63 2006 3 12
12. J.E. Teitelbaum, V.L. Fox, and F.J. Twarog Eosinophilic esophagitis in children: immunopathological analysis and response to fluticasone propionate Gastroenterology 12 2002 1216 1225
13. S.S. Aceves, J.F. Bastian, and R.O. Newbury Oral viscous budesonide: a potential new therapy for eosinophilic esophagitis in children Am J Gastroenterol 102 2007 2271 2279 quiz 2280
14. S.S. Aceves, R. Dohil, and R.O. Newbury Topical viscous budesonide suspension for treatment of eosinophilic esophagitis J Allergy Clin Immunol 116 2005 705 706
15. R. Dohil, R. Newbury, and L. Fox Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial Gastroenterology 139 2010 418 429
16. C.A. Liacouras, J.M. Spergel, and E. Ruchelli Eosinophilic esophagitis: a 10-year experience in 381 children Clin Gastroenterol Hepatol 3 2005 1198 1206
17. J.E. Markowitz, J.M. Spergel, and E. Ruchelli Elemental diet is an effective treatment for eosinophilic esophagitis in children and adolescents Am J Gastroenterol 98 2003 777 782
18. N. Gonsalves Eosinophilic esophagitis: history, nomenclature, and diagnostic guidelines Gastrointest Endosc Clin N Am 18 2008 1 9 vii
19. S.K. Gupta Noninvasive markers of eosinophilic esophagitis Gastrointest Endosc Clin N Am 18 2008 157 167 xi
20. P.E. Putnam Eosinophilic esophagitis in children: clinical manifestations Gastroenterol Clin North Am 37 2008 369 381 vi
21. S.S. Aceves, G.T. Furuta, and S.J. Spechler Integrated approach to treatment of children and adults with eosinophilic esophagitis Gastrointest Endosc Clin N Am 18 2008 195 217 xi
22. P.E. Putnam Eosinophilic esophagitis in children: clinical manifestations Gastrointest Endosc Clin N Am 18 2008 11 23 vii
23. R. Kiesslich, M. Goetz, and M.F. Neurath Virtual histology Best Pract Res Clin Gastroenterol 22 2008 883 897
24. R. Kiesslich, L. Gossner, and M. Goetz In vivo histology of Barrett's esophagus and associated neoplasia by confocal laser endomicroscopy Clin Gastroenterol Hepatol 4 2006 979 987
25. N.Q. Nguyen, and R.W. Leong Current application of confocal endomicroscopy in gastrointestinal disorders J Gastroenterol Hepatol 23 2008 1483 1491
26. H. Pohl, T. Rösch, and M. Vieth Miniprobe confocal laser microscopy for the detection of invisible neoplasia in patients with Barrett's oesophagus Gut 57 2008 1648 1653
27. H. Neumann, H. Vieth, and M. Vieth First description of eosinophilic esophagitis using confocal laser endomicroscopy (with video) Endoscopy 43 Suppl 2 2011 E66
28. M. Nakao, S. Yoshida, and S. Tanaka Optical biopsy of early gastroesophageal cancer by catheter-based reflectance-type laser-scanning confocal microscopy J Biomed Opt 13 2008 054043
29. S. Yoshida, S. Tanaka, and M. Hirata Optical biopsy of GI lesions by reflectance-type laser-scanning confocal microscopy Gastrointest Endosc 66 2007 144 149
30. G.J. Tearney, R.H. Webb, and B.E. Bouma Spectrally encoded confocal microscopy Opt Lett 23 1998 1152 1154
31. D. Yelin, C. Boudoux, and B.E. Bouma Large area confocal microscopy Opt Lett 32 2007 1102 1104
32. D. Kang, M.J. Suter, and C. Boudoux Comprehensive imaging of gastroesophageal biopsy samples by spectrally encoded confocal microscopy Gastrointest Endosc 71 2010 35 43
33. C. Boudoux, S. Yun, and W. Oh Rapid wavelength-swept spectrally encoded confocal microscopy Opt Express 13 2005 8214 8221
34. D. Yelin, B.E. Bouma, and S.H. Yun Double-clad fiber for endoscopy Opt Lett 29 2004 2408 2410
35. P. Thevenaz, U.E. Ruttimann, and M. Unser A pyramid approach to subpixel registration based on intensity IEEE Trans Image Process 7 1998 27 41
36. W.S. Rasband ImageJ 1997-2010 U.S. National Institutes of Health Bethesda, Maryland http://rsb.info.nih.gov/ij/ Accessed Nov 2010
37. R.D. Odze Pathology of eosinophilic esophagitis: what the clinician needs to know Am J Gastroenterol 104 2009 485 490
38. E.S. Dellon, W.B. Gibbs, and K.J. Fritchie Clinical, endoscopic, and histologic findings distinguish eosinophilic esophagitis from gastroesophageal reflux disease Clin Gastroenterol Hepatol 7 2009 1305 1313 quiz 1261
39. S. Mueller, T. Aigner, and D. Neureiter Eosinophil infiltration and degranulation in oesophageal mucosa from adult patients with eosinophilic oesophagitis: a retrospective and comparative study on pathological biopsy J Clin Pathol 59 2006 1175 1180
40. M. Chehade, M.A. Sampson, and R.A. Morotti Esophageal subepithelial fibrosis in children with eosinophilic esophagitis J Pediatr Gastroenterol Nutr 45 2007 319 328
41. D. Arifler, I. Pavlova, and A. Gillenwater Light scattering from normal and dysplastic cervical cells at different epithelial depths: finite-difference time-domain modeling with a perfectly matched layer boundary condition J Biomed Opt 8 2003 484 494
42. R. Drezek, A. Dunn, and R. Richards-Kortum A pulsed finite-difference time-domain (FDTD) method for calculating light scattering from biological cells over broad wavelength ranges Opt Express 6 2000 147 157
43. R. Drezek, M. Guillard, and T. Collier Light scattering from cervical cells throughout neoplastic progression: influence of nuclear morphology, DNA content, and chromatin texture J Biomed Opt 8 2003 7 16
44. P. Lacy, A. Becker, and R. Moqbel Wintrobe's clinical hematology The human eosinophil. 2003 2003 Lippincott Williams & Wilkins Baltimore (Md)
45. M.A. Yurkin, K.A. Semyanov, and V.P. Maltsev Discrimination of granulocyte subtypes from light scattering: theoretical analysis using a granulated sphere model Opt Express 15 2007 16561 16580
46. G.J. Puppels, P.M. Kemperman, and A. Sandilands Raman microspectroscopic approach to the study of human granulocytes Biophys J 60 1991 1046 1056
47. A. Brunsting, and P.F. Mullaney Differential light scattering from spherical mammalian cells Biophys J 15 1974 439 453
48. R. Drezek, A. Zuluaga, and R. Richards-Kortum Handbook of optical coherence tomography Relationship between microscopic structure and scattering properties. implications for OCT imaging 2002 Marcel Dekker New York (NY)
49. R. Snell An electron microscopic study of the human epidermal keratinocyte Z Zellforsch Mikrosk Anat 79 1967 492 506
50. G.J. Tearney, M.E. Brezinski, and J.F. Southern Determination of the refractive index of highly scattering human tissue by optical coherence tomography Opt Lett 20 1995 2258
51. L. Qiu, D.K. Pleskow, and R. Chuttani Multispectral scanning during endoscopy guides biopsy of dysplasia in Barrett's esophagus Nat Med 16 2010 603 606 1p following 606
52. A. Hoffman, R. Kiesslich, and A. Bender Acetic acid-guided biopsies after magnifying endoscopy compared with random biopsies in the detection of Barrett's esophagus: a prospective randomized trial with crossover design Gastrointest Endosc 64 2006 1 8
53. R. Sankaranarayanan, R. Wesley, and T. Somanathan Visual inspection of the uterine cervix after the application of acetic acid in the detection of cervical carcinoma and its precursors Cancer 83 1998 2150 2156
54. D. Kang, H. Yoo, and P. Jillella Comprehensive volumetric confocal microscopy with adaptive focusing Biomed Opt Express 2 2011 1412 1422
55. J.R. Lim, S.K. Gupta, and J.M. Croffie White specks in the esophageal mucosa: an endoscopic manifestation of non-reflux eosinophilic esophagitis in children Gastrointest Endosc 59 2004 835 838
56. J.R. Parfitt, J.C. Gregor, and N.G. Suskin Eosinophilic esophagitis in adults: distinguishing features from gastroesophageal reflux disease: a study of 41 patients Mod Pathol 19 2006 90 96
57. M.J. Suter, B.J. Vakoc, and P.S. Yachimski Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging Gastrointest Endosc 68 2008 745 753