Effect of G2706A and G1051A polymorphisms of the ABCA1 gene on the lipid, oxidative stress and homocystein levels in Turkish patients with polycystc ovary syndrome

Lipids in Health and Disease

Volumn 10, Issue , 2011, Pages

  Karadeniz, Muammer ^b   Erdoan, Mehmet ^a   Ayhan, Zengi ^a   Yalcn, Murat ^b   Olukman, Murat ^a   Cetinkalp, Sevki ^a   Alper, Gulinnaz E ^a   Eroglu, Zuhal ^a   Tetik, Asli ^a   Cetintas, Vildan ^a   Ozgen, Ahmet G ^a   Saygl, Fusun ^a   Ylmaz, Candeger ^a  

^a EGE UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^b SIFA UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; CHOLESTEROL; DISULFIDE; ESTRADIOL; FIBRINOGEN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HOMOCYSTEINE; INSULIN; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; NITRIC OXIDE; PRASTERONE SULFATE; PROLACTIN; TESTOSTERONE; THROMBIN ACTIVATABLE FIBRINOLYSIS INHIBITOR; TRIACYLGLYCEROL; ABC TRANSPORTER; BIOLOGICAL MARKER; HORMONE;

ADULT; ALLELE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DNA POLYMORPHISM; ENZYME BLOOD LEVEL; ESTROGEN BLOOD LEVEL; FEMALE; FIBRINOGEN BLOOD LEVEL; GENE LOCATION; GENOTYPE; GLUCOSE BLOOD LEVEL; HORMONE DETERMINATION; HUMAN; INSULIN BLOOD LEVEL; LIPID BLOOD LEVEL; OVARY POLYCYSTIC DISEASE; PROLACTIN BLOOD LEVEL; TESTOSTERONE BLOOD LEVEL; TRIACYLGLYCEROL BLOOD LEVEL; TURKEY (REPUBLIC); ADOLESCENT; AMINO ACID SUBSTITUTION; BLOOD; CASE CONTROL STUDY; GENE FREQUENCY; GENETIC ASSOCIATION; GENETICS; HAPLOTYPE; OXIDATIVE STRESS; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ADOLESCENT; ADULT; AMINO ACID SUBSTITUTION; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; DISULFIDES; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; HAPLOTYPES; HOMOCYSTEINE; HORMONES; HUMANS; LIPIDS; MALONDIALDEHYDE; NITRIC OXIDE; OXIDATIVE STRESS; POLYCYSTIC OVARY SYNDROME; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; TURKEY; YOUNG ADULT;

EID: 80054981884     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-10-193     Document Type: Article

References (38)

1. A practical approach to the diagnosis of polycystic ovary syndrome. Chang RJ, Am J Obstet Gynecol 2004 191 713 7 10.1016/j.ajog.2004.04.045 15467530 (Pubitemid 39298099)
2. Polycystic ovary syndrome. King J, J Midwifery Womens Health 2006 51 415 22 10.1016/j.jmwh.2006.01.008 17081931 (Pubitemid 44615960)
3. [Early metabolic abnormalities - insulin resistance, hyperinsulinemia, impaired glucose tolerance and diabetes, in adolescent girls with polycystic ovarian syndrome]. Otto-Buczkowska E, Jarosz-Chobot P, Deja G, Przegl Lek 2006 63 234 8 17080748
4. Increased serum neopterin levels in women with polycystic ovary syndrome. Barutcuoglu B, Bozdemir AE, Dereli D, Parildar Z, Mutaf MI, Ozmen D, Bayindir O, Ann Clin Lab Sci 2006 36 267 72 16951267 (Pubitemid 44335687)
5. Homocysteine and cardiovascular disease. Refsum H, Ueland PM, Nygard O, Vollset SE, Annu Rev Med 1998 49 31 62 10.1146/annurev.med.49.1.31 9509248 (Pubitemid 28197439)
6. Polycystic ovary syndrome and gynecological cancers: is there a link? Gadducci A, Gargini A, Palla E, Fanucchi A, Genazzani AR, Gynecol Endocrinol 2005 20 200 8 10.1080/09513590400021201 16019362 (Pubitemid 40862906)
7. Polycystic ovary syndrome and cancer. Balen A, Hum Reprod Update 2001 7 522 5 10.1093/humupd/7.6.522 11727859 (Pubitemid 33069609)
8. Prevalence and predictors of dyslipidemia in women with polycystic ovary syndrome. Legro RS, Kunselman AR, Dunaif A, Am J Med 2001 111 607 613 10.1016/S0002-9343(01)00948-2 11755503 (Pubitemid 34088070)
9. Atherogenic lipoprotein phenotype and low density lipoproteins size and subclasses in women with polycystic ovary syndrome. Berneis K, Rizzo M, Lazzarini V, Fruzzetti F, Carmina E, J Clin Endocrinol Metab 2007 92 186 189 17062762 (Pubitemid 46067529)
10. Incidence and treatment of metabolic syndrome in newly referred women with confirmed polycystic ovarian syndrome. Glueck CJ, Papanna R, Wang P, Goldenberg N, Sieve-Smith L, Metabolism 2003 52 908 915 10.1016/S0026-0495(03) 00104-5 12870169 (Pubitemid 36957780)
11. Risk factors for coronary artery disease in lean and obese women with the polycystic ovary syndrome. Conway GS, Agrawal R, Betteridge DJ, Jacobs HS, Clin Endocrinol (Oxf) 1992 37 119 125 10.1111/j.1365-2265.1992.tb02295.x
12. Tangier disease and ABCA1. Oram JF, Biochim Biophys Acta 2000 1529 321 30 11111099
13. The ATP binding cassette transporter ABC1, is required for the engulfment of corpses generated by apoptotic cell death. Luciani MF, Chimini G, EMBO J 1996 15 226 35 8617198 (Pubitemid 26029202)
14. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). The Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group, Hum Reprod 2004 19 41 7 14688154
15. Lipid peroxides in hepatic, gastrointestinal and pancreatic diseases. Yagi K, Free radicals in Diagnostic Medicine New York, NY, Plenum Press, Armstrong D, 1994 165 169
16. A rapid, simple spectrophometric method for simultaneous detection of nitrate and nitrite. Miranda KM, Espey MG, Wink DA, Nitric Oxide 2001 5 62 71 10.1006/niox.2000.0319 11178938 (Pubitemid 34146173)
17. Estimation of total, protein-bound and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Sedlak J, Lindsay RH, Anal Biochem 1968 25 192 205 4973948
18. The pathophysiology of polycystic ovary syndrome. Tsilchorozidou T, Overton C, Conway GS, Clin Endocrinol (Oxf) 2004 60 1 17 10.1046/j.1365-2265. 2003.01842.x (Pubitemid 38183491)
19. Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome. Apridonidze T, Essah PA, Iuorno MJ, Nestler JE, J Clin Endocrinol Metab 2005 90 1929 1935 10.1210/jc.2004-1045 15623819 (Pubitemid 40586223)
20. Polycystic ovary syndrome: A risk for coronary artery disease? Wild R, Am J Obstet Gynecol 2002 186 35 43 10.1067/mob.2002.119180 11810081 (Pubitemid 34093736)
21. Endothelial dysfunction in young women with polycystic ovary syndrome: relationship with insulin resistance and low-grade chronic inflammation. Tarkun I, Arslan BC, Cantürk Z, Türemen E, Sahin T, Duman C, J Clin Endocrinol Metab 2004 89 5592 6 10.1210/jc.2004-0751 15531516 (Pubitemid 39518445)
22. Effect of rosiglitazone on insulin resistance, C-reactive protein and endothelial function in non-obese young women with polycystic ovary syndrome. Tarkun I, Cetinarslan B, Türemen E, Sahin T, Cantürk Z, Komsuoglu B, Eur J Endocrinol 2005 153 115 21 10.1530/eje.1.01948 15994753 (Pubitemid 41038391)
23. The progesterone receptor PROGINS polymorphism is not related to oxidative stress factors in women with polycystic ovary syndrome. Karadeniz M, Erdogan M, Berdeli A, Tamsel S, Saygili F, Yilmaz C, Cardiovasc Diabetol 2007 5 6 29
24. 4 G/5 G polymorphism of PAI-1 gene and Alu-repeat I/D polymorphism of TPA gene in Turkish patients with polycystic ovary syndrome. Karadeniz M, Erdogan M, Berdeli A, Saygili F, Yilmaz C, J Assist Reprod Genet 2007 24 412 8 10.1007/s10815-007-9160-7 17661167 (Pubitemid 47497960)
25. Oxidative stress markers in young patients with polycystic ovary syndrome, the relationship between insulin resistances. Karadeniz M, Erdoan M, Tamsel S, Zengi A, Alper GE, Calayan O, Saygili F, Yilmaz C, Exp Clin Endocrinol Diabetes 2008 116 231 5 10.1055/s-2007-992154 18393129 (Pubitemid 351600585)
26. Characterization of groups of hyperandrogenic women with acanthosis nigricans, impaired glucose tolerance, and/or hyperinsulinemia. Dunaif A, Graf M, Mandeli J, Laumas V, Dobrjansky A, J Clin Endocrinol Metab 1987 65 499 507 10.1210/jcem-65-3-499 3305551 (Pubitemid 17131438)
27. Effects of luteinizing hormone, insulin, insulin-like growth factor-I and insulin-like growth factor small binding protein 1 in the polycystic ovary syndrome. Conway GS, Jacobs HS, Holly JM, Wass JA, Clin Endocrinol (Oxf) 1990 33 593 603 (Pubitemid 20346607)
28. Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome. Dunaif A, Segal KR, Futterweit W, Dobrjansky A, Diabetes 1989 38 1165 1174 10.2337/diabetes.38.9.1165 2670645 (Pubitemid 19250404)
29. Lipoprotein lipid concentrations and cardiovascular risk in women with polycystic ovary syndrome. Wild RA, Painter PC, Coulson PB, Carruth KB, Ranney GB, J Clin Endocrinol Metab 1985 61 946 951 10.1210/jcem-61-5-946 4044782 (Pubitemid 16218495)
30. Altered composition of high density lipoproteins in women with the polycystic ovary syndrome. Rajkhowa M, Neary RH, Kumpatla P, Game FL, Jones PW, Obhrai MS, Clayton RN, J Clin Endocrinol Metab 1997 82 3389 3394 10.1210/jc.82.10.3389 9329374 (Pubitemid 27419093)
31. Adverse lipid and coronary heart disease risk profiles in young women with polycystic ovary syndrome: results of a case-control study. Talbott E, Clerici A, Berga SL, Kuller L, Guzick D, Detre K, Daniels T, Engberg RA, J Clin Epidemiol 1998 51 415 422 10.1016/S0895-4356(98)00010-9 9619969 (Pubitemid 28223308)
32. Incidence and treatment of metabolic syndrome in newly referred women with confirmed polycystic ovarian syndrome. Glueck CJ, Papanna R, Wang P, Goldenberg N, Sieve-Smith L, Metabolism 2003 52 908 915 10.1016/S0026-0495(03) 00104-5 12870169 (Pubitemid 36957780)
33. Apolipoprotein E gene polymorphism and polycystic ovary syndrome patients in Western Anatolia, Turkey. Cetinkalp S, Karadeniz M, Erdogan M, Zengi A, Cetintas V, Tetik A, Eroglu Z, Kosova B, Ozgen AG, Saygili F, Yilmaz C, J Assist Reprod Genet 2009 26 1 6 10.1007/s10815-008-9280-8 19057990
34. ABCA1: the gatekeeper for eliminating excess tissue cholesterol. Oram JF, Lawn RM, J Lipid Res 2001 42 1173 1179 11483617 (Pubitemid 32744239)
35. ATP-binding cassette transporter A1 (ABCA1) functions as a cholesterol efflux regulatory protein. Wang N, Silver DL, Thiele C, Tall AR, J Biol Chem 2001 276 23742 23747 10.1074/jbc.M102348200 11309399
36. Associations between two common polymorphisms in the ABCA1 gene and subclinical atherosclerosis: Multi-Ethnic Study of Atherosclerosis (MESA). Benton JL, Ding J, Tsai MY, Shea S, Rotter JI, Burke GL, Post W, Atherosclerosis 2007 193 352 60 10.1016/j.atherosclerosis.2006.06.024 16879828 (Pubitemid 47058097)
37. A common variant in the ABCA1 gene is associated with a lower risk for premature coronary heart disease in familial hypercholesterolaemia. Cenarro A, Artieda M, Castillo S, Mozas P, Reyes G, Tejedor D, Alonso R, Mata P, Pocoví M, Civeira F, Spanish FH group, J Med Genet 2003 40 163 168 10.1136/jmg.40.3.163 12624133 (Pubitemid 36315386)
38. Genetic variation in ABC transporter A1 contributes to HDL cholesterol in the general population. Frikke-Schmidt, Nordestgaard BG, Jensen GB, Tybjaerg-Hansen A, J Clin Invest 2004 114 1343 1353 15520867 (Pubitemid 40385306)