Neonatal screening: Mean Haemoglobin and red cell indices in cord blood from Omani neonates

Sultan Qaboos University Medical Journal

Volumn 11, Issue 4, 2011, Pages 462-469

  Alkindi, Salam ^a   Pathare, Anil ^b   Al Madhani, Ali ^c   Al Zadjali, Shoaib ^b   Al Haddabi, Hamood ^b   Al Abri, Qamariya ^b   Gravell, David ^b   Mathew, Mariam ^b   Krishnamoorthy, Rajagopal ^d  

^a SULTAN QABOOS UNIVERSITY   (Oman)

^b SULTAN QABOOS UNIVERSITY HOSPITAL   (Oman)

^c Sohar Hospital   (Oman)

^d HÔPITAL ROBERT DEBRÉ   (France)

Author keywords

Alpha thalassaemia; Haemoglobin; Neonatal; Reference range; Screening; Variants

Indexed keywords

EID: 80054976057     PISSN: 2075051X     EISSN: 20750528     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. White JM, Byrne M, Richards R, Buchanan T, Katsoulis E, Weerasingh K. Red cell genetic abnormalities in Peninsular Arabs: Sickle hemoglobin, G6PD defciency, and alpha and beta thalassemia. J Med Genet 1986; 23:245-51.
2. White JM, Christie BS, Nam D, Daar S, Higgs DR. Frequency and clinical signifcance of erythrocyte genetic abnormalities in Omanis. J Med Genet 1993; 30:396-400.
3. El-Hazmi MA, Al-Swailem AR, Al-Faleh FZ, Warsy AS. Frequency of glucose-6-phosphate dehydrogenase, pyruvate kinase and hexokinase defciency in the Saudi population. Hum Hered 1986; 36:45-9.
4. Al-Awamy BH, Al-Muzan M, Al-Turki M, Serjeant GR. Neonatal screening for sickle cell disease in the Eastern Province of Saudi Arabia. Trans R Soc Trop Med Hyg 1984; 78:792-4.
5. Al-Riyami AA, Suleiman AJ, Aff M, Al-Lamki ZM, Daar S. A community-based study of common hereditary blood disorders in Oman. East Mediterr Health J 2001; 7:1004-11.
6. Al Kindi S, Zadjali S, Al Madhani A, Daar SD, Al Haddabi H, Al Abri Q, et al. Forecasting hemoglobinopathy burden through neonatal screening in Omani neonates. Hemoglobin 2010; 34:135-44.
7. Nasserullah Z, Al-Jame A, Abu Srair H, Al-Qatari G, Al-Naim S, Al-Aqib A, et al. Neonatal screening for sickle cell disease, glucose-6-phosphate dehydrogenase defciency and α-thalassemia in Qatif and Al Hasa. Ann Saudi Med 1998; 18:289-92.
8. Quadri MI, Islam SIAM, Nasserullah Z. Te efect of α-thalassemia on cord blood red cell indices and interaction with sickle cell gene, Ann Saudi Med 2000; 20:367-70.
9. Birth rate in Oman. From: http://www.nationmaster.com/country/mu-oman/peo-people Accessed: Apr 2011.
10. Rogers BB, Wessels RA, Ou CN, Bufone GJ. High-performance liquid chromatography in the diagnosis of hemoglobinopathies and thalassemias. Report of three cases. Am J Clin Pathol 1985; 84:671-4.
11. Lorey F, Cunningham G, Shafer F, Lubin B, Vichinsky E. Universal screening for hemoglobinopathies using high-performance liquid chromatography: Clinical results of 2.2 million screens. Eur J Hum Genet 1994; 24:262-71.
12. Rajab A, Patton MA. A study of consanguinity in the Sultanate of Oman. Ann Hum Biol 2000; 27:321-6.
13. Weatherall DJ. Abnormal hemoglobins in the neonatal period and their relationship to thalassemia. Br J Haematol 1963; 9:265-77.
14. Wasi P, Na-Nakorn S, Pootrakul S. Te α-thalassemias. Clin Haematol 1974; 3:383-410.
15. Higgs DR, Pressley L, Clegg JB, Weatherall DJ, Higgs S, Carey P, et al. Detection of beta-thalassemia in negro infants. Br J Haematol 1980; 46:39-46.
16. Higgs DR, Vickers MA, Wilkie AOM, Pretorius I-M, Jarman AP, Weatheral DJ. A review of the molecular genetics of the human α-globin gene cluster. Blood 1989; 73:1091-108.
17. Weatheral DJ. Te Talassemias. In: Beutler E, Litchmen MA, Coller BS, Kipps TJ, Eds. William's Hematology. 5th Ed, (International ed.). New York: McGraw-Hill Inc, Health Professions Division, 1995. Pp. 581-615.
18. Pathare AV, Al Kindi S, Al Zadjali S, Al Abri Q, Al Haddabi H, Muralitharan S, et al. Newborn hemoglobinopathy carrier screening: Towards comprehensive and improved patient care of sickle cell disease in Oman, a cost efective analysis (Abstr. 806) Hematol J 2006; 91:296-7.