Electrophoretic isolation of saponin fractions from Saponinum album and their evaluation in synergistically enhancing the receptor-specific cytotoxicity of targeted toxins

Electrophoresis

Volumn 32, Issue 21, 2011, Pages 3085-3089

  Thakur, Mayank ^a   Weng, Alexander ^a   Bachran, Diana ^a   Riese, Sebastian B ^a   Böttger, Stefan ^b   Melzig, Matthias F ^b   Fuchs, Hendrik ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Electrophoretic mobility; Epidermal growth factor; Gel electrophoresis; Saponin isolation; Targeted toxin

Indexed keywords

CYTOTOXICITY; MAMMALS; METABOLITES;

COMMERCIAL MIXTURES; EFFECTIVE FRACTIONS; ELECTROPHORETIC METHODS; EPIDERMAL GROWTH FACTORS; GEL ELECTROPHORESIS; GYPSOPHILA SPECIES; HPLC ANALYSIS; INHIBITION OF TUMOR GROWTH; SAPONIN ISOLATION; TARGETED TOXIN;

ELECTROPHORETIC MOBILITY;

EPIDERMAL GROWTH FACTOR; SAPONIN; TOXIN;

ARTICLE; CELL VIABILITY; CHEMICAL ANALYSIS; CYTOTOXICITY TEST; DRUG ISOLATION; DRUG PURITY; DRUG TARGETING; ELECTROPHORETIC MOBILITY; ELECTROSPRAY MASS SPECTROMETRY; GEL ELECTROPHORESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; NONHUMAN; PROTEIN EXPRESSION; SEPARATION TECHNIQUE; THIN LAYER CHROMATOGRAPHY;

EID: 80054975689     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.201100155     Document Type: Article

References (29)

1. Bachran, C., Bachran, S., Sutherland, M., Bachran, D., Fuchs, H., Mini Rev. Med. Chem. 2008, 8, 575-584.
2. Chauhan, N. S., Sharma, V., Thakur, M., Dixit, V. K., Zhong Xi Yi Jie He Xue Bao 2010, 8, 613-623.
3. Tran, Q. L., Adnyana, I. K., Tezuka, Y., Nagaoka, T., J. Nat. Prod. 2001, 64, 456-461.
4. Bachran, C., Durkop, H., Sutherland, M., Bachran, D., Muller, C., Weng, A., Melzig, M. F., Fuchs, H., J. Immunother. 2009, 32, 713-725.
5. Bachran, C., Heisler, I., Bachran, D., Dassler, K., Ervens, J., Melzig, M. F., Fuchs, H., Cancer Biol. Ther. 2008, 7, 237-242.
6. Hebestreit, P., Weng, A., Bachran, C., Fuchs, H., Melzig, M. F., Toxicon 2006, 47, 330-335.
7. Heisler, I., Sutherland, M., Bachran, C., Hebestreit, P., Schnitger, A., Melzig, M. F., Fuchs, H., J. Control. Release 2005, 106, 123-137.
8. Bachran, D., Schneider, S., Bachran, C., Urban, R., Weng, A., Melzig, M. F., Hoffmann, C., Kaufmann, A. M., Fuchs, H., Int. J. Cancer 2010, 127, 1453-1461.
9. Campbell, R. B., Fukumura, D., Brown, E. B., Mazzola, L. M., Izumi, M., Jain, R. K., Torchilin, V. P., Munn, L. C., Cancer Res. 2002, 62, 6831-6836.
10. Eichhorn, M. E., Strieth, S., Krasnici, S., Sauer, B., Angiogenesis 2004, 7, 133-141.
11. Hamblin, M. R., Rajadhyaksha, M., Momma, T., Soukos, N. S., Hasan, T., Br. J. Cancer 1999, 81, 261-268.
12. Bachran, D., Schneider, S., Bachran, C., Urban, R., Weng, A., Kauffman, A. M., Fuchs, H., Int. J. Cancer 2010, 127, 1453-1461.
13. Weng, A., Bachran, D., Gorick, C., Bachran, C., Siems, K. J., Thakur, M., Fuchs, H., Melzig, M. F., Planta Med. 2009, 75, 1421-1422.
14. Sommer, S. S., Anal. Biochem. 1979, 98, 8-12.
15. Tsiganos, C. P., Muir, H., Biochem. J. 1969, 113, 885-894.
16. Gevrenova, R., Voutquenne-Nazabadioko, L., Harakat, D., Prost, E., Henry, M., Magn. Reson. Chem. 2006, 44, 686-691.
17. Nygren, P., Hagberg, H., Glimelius, B., Sundstrom, C., Ann. Oncol. 1994, 5, 127-131.
18. Heisler, I., Sutherland, M., Bachran, C., Hebestreit, P., Melzig, M. F., Fuchs, H., J. Control. Release 2005, 106, 123-137.
19. Weng, A., Thakur, M., Schindler, A., Fuchs, H., Melzig, M. F., Pharmazie 2011, 66, 1-3.
20. Drechsel, W. D., Math. Biosci. 2008, 213, 135-140.
21. Lozano, M. V., Torrecilla, D., Torres, D., Vidal, A., Biomacromolecules 2008, 9, 2186-2193.
22. Perumal, O. P., Inapagolla, R., Kannan, S., Kannan, R. M., Biomaterials 2008, 29, 3469-3476.
23. Bachran, C., Sutherland, M., Heisler, I., Hebestreit, P., Melzig, M. F., Fuchs, H., Exp. Biol. Med. (Maywood) 2006, 231, 412-420.
24. Lan, K. L., Ou-Yang, F., Yen, S. H., Shih, H. L., Lan, K. H., Clin. Exp. Metastasis, 2010, 27, 307-318.
25. Wunderlich, S., Pliquett, F., Lap, V., Grimm, E., Kantcheva, M. R., Goltzev, V., Markov, M. S., Bioelectrochem. Bioenerg. 1987, 17, 35-41.
26. Gogelein, H., Huby, A., Biochim. Biophys. Acta 1984, 773, 32-38.
27. Davies, R., Preece, A. W., Clin. Phys. Physiol. Meas. 1983, 4, 129-140.
28. Oleszek, W. A., J. Chromatogr. A 2002, 967, 147-162.
29. Emara, S., Mohamed, K. M., Masujima, T., Yamasaki, K., Biomed. Chromatogr. 2001, 15, 252-256.