메뉴 건너뛰기




Volumn 668, Issue SUPPL. 1, 2011, Pages

Assessment of research models for testing gene-environment interactions

Author keywords

Adult stem cell; Embryonic stem cells (ESCs); Genome wide association studies (GWAS); Inbred strain; Individual risk factor; Induced pluripotent stem cells (iPSCs)

Indexed keywords

ADULT STEM CELL; CONFERENCE PAPER; DNA SEQUENCE; EMBRYONIC STEM CELL; EXPERIMENTAL MODEL; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS MAPPING; RISK ASSESSMENT; XENOBIOTIC METABOLISM;

EID: 80054972495     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.05.084     Document Type: Conference Paper
Times cited : (4)

References (132)
  • 3
    • 21744441322 scopus 로고    scopus 로고
    • Human embryonic stem cells as a model for nutritional programming: An evaluation
    • DOI 10.1016/j.reprotox.2005.04.010, PII S0890623805000961, 33rd Annual Conference of the European Teratology Society
    • C. Allegrucci, C.N. Denning, P. Burridge, W. Steele, K.D. Sinclair, and L.E. Young Human embryonic stem cells as a model for nutritional programming: an evaluation Reprod. Toxicol. 20 2005 353 367 (Pubitemid 40943556)
    • (2005) Reproductive Toxicology , vol.20 , Issue.3 , pp. 353-367
    • Allegrucci, C.1    Denning, C.N.2    Burridge, P.3    Steele, W.4    Sinclair, K.D.5    Young, L.E.6
  • 4
    • 60649084367 scopus 로고    scopus 로고
    • Induced pluripotent stem cells: Current progress and potential for regenerative medicine
    • G. Amabile, and A. Meissner Induced pluripotent stem cells: current progress and potential for regenerative medicine Trends Mol. Med. 15 2009 59 68
    • (2009) Trends Mol. Med. , vol.15 , pp. 59-68
    • Amabile, G.1    Meissner, A.2
  • 5
    • 1542433084 scopus 로고
    • The mouse: Toxicology
    • S.C. Gad, C.P. Chengelis, Marcel Dekker, Inc. New York, NY
    • J.M. Andress The mouse: toxicology S.C. Gad, C.P. Chengelis, Animal Models in Toxicology 1992 Marcel Dekker, Inc. New York, NY 165 232
    • (1992) Animal Models in Toxicology , pp. 165-232
    • Andress, J.M.1
  • 7
    • 70349971144 scopus 로고    scopus 로고
    • Mass spectrometry based metabolomics and enzymatic assays for functional genomics
    • R. Baran, W. Reindl, and T.R. Northen Mass spectrometry based metabolomics and enzymatic assays for functional genomics Curr. Opin. Microbiol. 12 2009 547 552
    • (2009) Curr. Opin. Microbiol. , vol.12 , pp. 547-552
    • Baran, R.1    Reindl, W.2    Northen, T.R.3
  • 8
    • 0034143526 scopus 로고    scopus 로고
    • Tibetan and Andean patterns of adaptation to high-altitude hypoxia
    • C.M. Beall Tibetan and Andean patterns of adaptation to high-altitude hypoxia Hum. Biol. 72 2000 201 228 (Pubitemid 30132306)
    • (2000) Human Biology , vol.72 , Issue.1 , pp. 201-228
    • Beall, C.M.1
  • 10
    • 79959436316 scopus 로고    scopus 로고
    • Translating research into clinical scale manufacturing of mesenchymal stromal cells
    • K. Bieback, S. Kinzebach, and M. Karagianni Translating research into clinical scale manufacturing of mesenchymal stromal cells Stem Cells Int. 2010 2011 193519
    • (2011) Stem Cells Int. , vol.2010 , pp. 193519
    • Bieback, K.1    Kinzebach, S.2    Karagianni, M.3
  • 11
    • 7744221326 scopus 로고    scopus 로고
    • The mouse phenome project
    • DOI 10.1007/s10709-004-1438-4
    • M.A. Bogue, and S.C. Grubb The mouse phenome project Genetica 122 2004 71 74 (Pubitemid 39459526)
    • (2004) Genetica , vol.122 , Issue.1 , pp. 71-74
    • Bogue, M.A.1    Grubb, S.C.2
  • 12
    • 0036641368 scopus 로고    scopus 로고
    • Using mouse models to dissect the genetics of obesity
    • DOI 10.1016/S0168-9525(02)02703-8, PII S0168952502027038
    • G.A. Brockmann, and M.R. Bevova Using mouse models to dissect the genetics of obesity Trends Genet. 18 2002 367 376 (Pubitemid 34804449)
    • (2002) Trends in Genetics , vol.18 , Issue.7 , pp. 367-376
    • Brockmann, G.A.1    Bevova, M.R.2
  • 13
    • 71049118490 scopus 로고    scopus 로고
    • Endless possibilities: Stem cells and the vision for toxicology testing in the 21st century
    • R.E. Chapin, and D.B. Stedman Endless possibilities: stem cells and the vision for toxicology testing in the 21st century Toxicol. Sci. 112 2009 17 22
    • (2009) Toxicol. Sci. , vol.112 , pp. 17-22
    • Chapin, R.E.1    Stedman, D.B.2
  • 14
    • 77957845081 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells; Historical overview and concepts
    • P. Charbord Bone marrow mesenchymal stem cells; historical overview and concepts Hum. Gene Ther. 21 2010 1045 1056
    • (2010) Hum. Gene Ther. , vol.21 , pp. 1045-1056
    • Charbord, P.1
  • 17
    • 79951868206 scopus 로고    scopus 로고
    • Clinical proteomics: Current status, challenges, and future perspectives
    • S.H. Chiou, and C.Y. Wu Clinical proteomics: current status, challenges, and future perspectives Kaohsiung J. Med. Sci. 27 2011 1 14
    • (2011) Kaohsiung J. Med. Sci. , vol.27 , pp. 1-14
    • Chiou, S.H.1    Wu, C.Y.2
  • 18
    • 0242291131 scopus 로고    scopus 로고
    • The nature and identification of quantitative trait loci: A community's view
    • Complex Trait Consortium The nature and identification of quantitative trait loci: a community's view Nat. Rev. Genet. 4 2003 911 916
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 911-916
    • Trait Consortium, C.1
  • 19
    • 14644441018 scopus 로고    scopus 로고
    • The Collaborative Cross, a community resource for the genetic analysis of complex traits
    • Complex Trait Consortium The Collaborative Cross, a community resource for the genetic analysis of complex traits Nat. Genet. 36 2004 1133 1137
    • (2004) Nat. Genet. , vol.36 , pp. 1133-1137
    • Trait Consortium, C.1
  • 20
    • 4344645792 scopus 로고    scopus 로고
    • Marrow-isolated adult multilineage inducible (MIAMI) cells, a unique population of postnatal young and old human cells with extensive expansion and differentiation potential
    • DOI 10.1242/jcs.01103
    • G. D'Ippolito, S. Diabira, G.A. Howard, P. Menei, B.A. Roos, and P.C. Schiller Marrow-isolated adult multilineage inducible (MIAMI) cells, a unique population of postnatal young and old human cells with extensive expansion and differentiation potential J. Cell Sci. 117 2004 2971 2981 (Pubitemid 39117672)
    • (2004) Journal of Cell Science , vol.117 , Issue.14 , pp. 2971-2981
    • D'Ippolito, G.1    Diabira, S.2    Howard, G.A.3    Menei, P.4    Roos, B.A.5    Schiller, P.C.6
  • 23
    • 0031000206 scopus 로고    scopus 로고
    • Genome scan for teratogen-induced clefting susceptibility loci in the mouse: Evidence of both allelic and locus heterogeneity distinguishing cleft lip and cleft palate
    • DOI 10.1073/pnas.94.10.5231
    • S.R. Diehl, and R.P. Erickson Genome scan for teratogen-induced clefting susceptibility loci in the mouse: evidence of both allelic and locus heterogeneity distinguishing cleft lip and cleft palate Proc. Natl. Acad. Sci. U. S. A. 94 1997 5231 5236 (Pubitemid 27214766)
    • (1997) Proceedings of the National Academy of Sciences of the United States of America , vol.94 , Issue.10 , pp. 5231-5236
    • Diehl, S.R.1    Erickson, R.P.2
  • 24
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • DOI 10.1038/292154a0
    • M.J. Evans, and M.H. Kaufman Establishment in culture of pluripotential cells from mouse embryos Nature 292 1981 154 156 (Pubitemid 11050741)
    • (1981) Nature , vol.292 , Issue.5819 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 25
    • 77950995392 scopus 로고    scopus 로고
    • Hemangioblastic derivatives from human induced pluripotent stem cells exhibit limited expansion and early senescence
    • Q. Feng, S.J. Lu, I. Klimanskaya, I. Gomes, D. Kim, Y. Chung, G.R. Honig, K.S. Kim, and R. Lanza Hemangioblastic derivatives from human induced pluripotent stem cells exhibit limited expansion and early senescence Stem Cells 28 2010 704 712
    • (2010) Stem Cells , vol.28 , pp. 704-712
    • Feng, Q.1    Lu, S.J.2    Klimanskaya, I.3    Gomes, I.4    Kim, D.5    Chung, Y.6    Honig, G.R.7    Kim, K.S.8    Lanza, R.9
  • 27
    • 77449107448 scopus 로고    scopus 로고
    • Improving toxicity screening and drug development by using genetically defined strains
    • G. Proetzel, M.V. Wiles, Humana Press New York, NY
    • M.F.W. Festing Improving toxicity screening and drug development by using genetically defined strains G. Proetzel, M.V. Wiles, Mouse Models for Drug Discovery, Methods in Molecular Biology 602 2010 Humana Press New York, NY 1 21
    • (2010) Mouse Models for Drug Discovery, Methods in Molecular Biology 602 , pp. 1-21
    • Festing, M.F.W.1
  • 28
    • 15944376562 scopus 로고    scopus 로고
    • Strategies for mapping and cloning quantitative trait genes in rodents
    • DOI 10.1038/nrg1576
    • J. Flint, W. Valdar, S. Shifman, and R. Mott Strategies for mapping and cloning quantitative trait genes in rodents Nat. Rev. Genet. 6 2005 271 286 (Pubitemid 40469047)
    • (2005) Nature Reviews Genetics , vol.6 , Issue.4 , pp. 271-286
    • Flint, J.1    Valdar, W.2    Shifman, S.3    Mott, R.4
  • 29
    • 11144285884 scopus 로고    scopus 로고
    • DNA methylation pattern in human zygotes and developing embryos
    • DOI 10.1530/rep.1.00217
    • H. Fulka, M. Mrazek, O. Tepla, and J. Fulka Jr. DNA methylation pattern in human zygotes and developing embryos Reproduction 128 2004 703 708 (Pubitemid 40028546)
    • (2004) Reproduction , vol.128 , Issue.6 , pp. 703-708
    • Fulka, H.1    Mrazek, M.2    Tepla, O.3    Fulka Jr., J.4
  • 32
    • 79952899995 scopus 로고    scopus 로고
    • Methods for making induced pluripotent stem cells: Reprogramming a la carte
    • F. Gonzalez, S. Boue, and J.C. Belmonte Methods for making induced pluripotent stem cells: reprogramming a la carte Nat. Rev. Genet. 12 2011 231 242
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 231-242
    • Gonzalez, F.1    Boue, S.2    Belmonte, J.C.3
  • 34
    • 54949110207 scopus 로고    scopus 로고
    • Heterogeneity of embryonic and adult stem cells
    • T. Graf, and M. Stadtfeld Heterogeneity of embryonic and adult stem cells Cell Stem Cell 3 2008 480 483
    • (2008) Cell Stem Cell , vol.3 , pp. 480-483
    • Graf, T.1    Stadtfeld, M.2
  • 35
    • 79951922704 scopus 로고    scopus 로고
    • Similarities and differences in the expression of drug-metabolizing enzymes between human hepatic cell lines and primary human hepatocytes
    • L. Guo, S. Dial, L. Shi, W. Branham, J. Liu, J.L. Fang, B. Green, H. Deng, J. Kaput, and B. Ning Similarities and differences in the expression of drug-metabolizing enzymes between human hepatic cell lines and primary human hepatocytes Drug Metab. Dispos. 39 2011 528 538
    • (2011) Drug Metab. Dispos. , vol.39 , pp. 528-538
    • Guo, L.1    Dial, S.2    Shi, L.3    Branham, W.4    Liu, J.5    Fang, J.L.6    Green, B.7    Deng, H.8    Kaput, J.9    Ning, B.10
  • 36
    • 67649202201 scopus 로고    scopus 로고
    • Population-based discovery of toxicogenomices biomarkers for hepatotoxicity using a laboratory strain diversity panel
    • A.H. Harrill, P.K. Ross, D.M. Gatti, D.W. Threadgill, and I. Rusyn Population-based discovery of toxicogenomices biomarkers for hepatotoxicity using a laboratory strain diversity panel Toxicol. Sci. 110 2009 235 243
    • (2009) Toxicol. Sci. , vol.110 , pp. 235-243
    • Harrill, A.H.1    Ross, P.K.2    Gatti, D.M.3    Threadgill, D.W.4    Rusyn, I.5
  • 38
    • 50549218525 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • L. Hayflick The limited in vitro lifetime of human diploid cell strains Exp. Cell Res. 37 1965 614 636
    • (1965) Exp. Cell Res. , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 41
    • 13144306071 scopus 로고    scopus 로고
    • Genome-wide association studies for common diseases and complex traits
    • DOI 10.1038/nrg1521
    • J.N. Hirschhorn, and M.J. Daly Genome-wide association studies for common diseases and complex traits Nat. Rev. Genet. 6 2005 95 108 (Pubitemid 40179532)
    • (2005) Nature Reviews Genetics , vol.6 , Issue.2 , pp. 95-108
    • Hirschhorn, J.N.1    Daly, M.J.2
  • 42
    • 77749279749 scopus 로고    scopus 로고
    • Neural differentiation of human induced pluripotent stem cells follows developmental principles with variable potency
    • B.Y. Hu, J.P. Weick, J. Yu, L.X. Ma, X.Q. Zhang, J.A. Thomson, and S.C. Zhang Neural differentiation of human induced pluripotent stem cells follows developmental principles with variable potency Proc. Natl. Acad. Sci. U. S. A. 107 2010 4335 4340
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 4335-4340
    • Hu, B.Y.1    Weick, J.P.2    Yu, J.3    Ma, L.X.4    Zhang, X.Q.5    Thomson, J.A.6    Zhang, S.C.7
  • 44
    • 52549130734 scopus 로고    scopus 로고
    • The Collaborative Cross, developing a resource for mammalian systems genetics: A status report of the Wellcome Trust cohort
    • F.A. Iraqi, G. Churchill, and R. Mott The Collaborative Cross, developing a resource for mammalian systems genetics: a status report of the Wellcome Trust cohort Mamm. Genome 19 2008 379 381
    • (2008) Mamm. Genome , vol.19 , pp. 379-381
    • Iraqi, F.A.1    Churchill, G.2    Mott, R.3
  • 45
    • 79952994834 scopus 로고    scopus 로고
    • Advances in the treatment of type 2 diabetes mellitus
    • Z.H. Israili Advances in the treatment of type 2 diabetes mellitus Am. J. Ther. 18 2011 117 152
    • (2011) Am. J. Ther. , vol.18 , pp. 117-152
    • Israili, Z.H.1
  • 48
    • 47549109593 scopus 로고    scopus 로고
    • A comparative study of genome-wide SNP, CGH microarray and protein expression analysis to explore genotypic and phenotypic mechanisms of acquired antiestrogen resistance in breast cancer
    • DOI 10.1007/s10549-007-9758-6
    • N. Johnson, V. Speirs, N.J. Curtin, and A.G. Hall A comparative study of genome-wide SNP, CGH microarray and protein expression analysis to explore genotypic and phenotypic mechanisms of acquired antiestrogen resistance in breast cancer Breast Cancer Res. Treat. 111 2008 55 63 (Pubitemid 352009227)
    • (2008) Breast Cancer Research and Treatment , vol.111 , Issue.1 , pp. 55-63
    • Johnson, N.1    Speirs, V.2    Curtin, N.J.3    Hall, A.G.4
  • 49
    • 0036849530 scopus 로고    scopus 로고
    • Provisional mapping of quantitative trait loci modulating the acoustic startle response and prepulse inhibition of acoustic startle
    • DOI 10.1016/S0893-133X(02)00333-0, PII S0893133X02003330
    • R. Joober, J.M. Zarate, G.A. Rouleau, E. Skamene, and P. Boksa Provisional mapping of quantitative trait loci modulating the acoustic startle response and prepulse inhibition of acoustic startle Neuropsychopharmacology 27 2002 765 781 (Pubitemid 35335893)
    • (2002) Neuropsychopharmacology , vol.27 , Issue.5 , pp. 765-781
    • Joober, R.1    Zarate, J.-M.2    Rouleau, G.-A.3    Skamene, E.4    Boksa, P.5
  • 52
    • 0038736019 scopus 로고
    • The structure and uses of genetically homogeneous lines of animals
    • J.G. Wilson, F.C. Fraser, Research Procedures and Data Analysis Plenum Press New York, NY
    • H. Kalter The structure and uses of genetically homogeneous lines of animals J.G. Wilson, F.C. Fraser, Handbook of Teratology Research Procedures and Data Analysis 4 1979 Plenum Press New York, NY 155 190
    • (1979) Handbook of Teratology , vol.4 , pp. 155-190
    • Kalter, H.1
  • 53
    • 79952080601 scopus 로고    scopus 로고
    • Stem cells in toxicology: Fundamental biology and practical considerations
    • K.S. Kang, and J.E. Trosko Stem cells in toxicology: fundamental biology and practical considerations Toxicol. Sci. 120 2011 S269 S289
    • (2011) Toxicol. Sci. , vol.120
    • Kang, K.S.1    Trosko, J.E.2
  • 54
    • 42249110345 scopus 로고    scopus 로고
    • Nutrigenomics research for personalized nutrition and medicine
    • J. Kaput Nutrigenomics research for personalized nutrition and medicine Curr. Opin. Biotechnol. 19 2008 110 120
    • (2008) Curr. Opin. Biotechnol. , vol.19 , pp. 110-120
    • Kaput, J.1
  • 55
    • 4844230290 scopus 로고    scopus 로고
    • vy phenotype: Caloric restriction, genotype, diet X genotype interactions
    • DOI 10.1152/physiolgenomics.00065.2003
    • J. Kaput, K.G. Klein, E.J. Reyes, W.A. Kibbe, C.A. Cooney, B. Jovanovic, W.J. Visek, and G.L. Wolff Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, genotype, diet x genotype interactions Physiol. Genomics 18 2004 316 324 (Pubitemid 39319515)
    • (2004) Physiological Genomics , vol.18 , pp. 316-324
    • Kaput, J.1    Klein, K.G.2    Reyes, E.J.3    Kibbe, W.A.4    Cooney, C.A.5    Jovanovic, B.6    Visek, W.J.7    Wolff, G.L.8
  • 57
    • 1842483155 scopus 로고    scopus 로고
    • Nutritional genomics: The next frontier in the postgenomic era
    • DOI 10.1152/physiolgenomics.00107.2003
    • J. Kaput, and R.L. Rodriguez Nutritional genomics: the next frontier in the postgenomic era Physiol. Genomics 16 2004 166 177 (Pubitemid 38420031)
    • (2004) Physiological Genomics , vol.16 , pp. 166-177
    • Kaput, J.1    Rodriguez, R.L.2
  • 60
    • 79958232983 scopus 로고    scopus 로고
    • Gene-manipulated embryonic stem cells for rat transgenesis
    • M. Kawamata, and T. Ochiya Gene-manipulated embryonic stem cells for rat transgenesis Cell Mol. Life Sci. 68 2011 1911 1915
    • (2011) Cell Mol. Life Sci. , vol.68 , pp. 1911-1915
    • Kawamata, M.1    Ochiya, T.2
  • 61
    • 77957342967 scopus 로고    scopus 로고
    • Strategies for identifying the genetic basis of dyslipidemia: Genome-wide association studies vs. The resequencing of extremes
    • C.C. Khor, and D.L. Goh Strategies for identifying the genetic basis of dyslipidemia: genome-wide association studies vs. the resequencing of extremes Curr. Opin. Lipidol. 21 2010 123 127
    • (2010) Curr. Opin. Lipidol. , vol.21 , pp. 123-127
    • Khor, C.C.1    Goh, D.L.2
  • 62
  • 65
    • 68049124983 scopus 로고    scopus 로고
    • Human embryonic stem cells as a model for embryotoxicity screening
    • A. Krtolica, D. Ilic, O. Genbacev, and R.K. Miller Human embryonic stem cells as a model for embryotoxicity screening Regen. Med. 4 2009 449 459
    • (2009) Regen. Med. , vol.4 , pp. 449-459
    • Krtolica, A.1    Ilic, D.2    Genbacev, O.3    Miller, R.K.4
  • 66
    • 42449157075 scopus 로고    scopus 로고
    • Profiling techniques in nutrition and health research
    • M. Kussmann, S. Rezzi, and H. Daniel Profiling techniques in nutrition and health research Curr. Opin. Biotechnol. 19 2008 83 99
    • (2008) Curr. Opin. Biotechnol. , vol.19 , pp. 83-99
    • Kussmann, M.1    Rezzi, S.2    Daniel, H.3
  • 67
    • 22544441601 scopus 로고    scopus 로고
    • How malaria has affected the human genome and what human genetics can teach us about malaria
    • DOI 10.1086/432519
    • D.P. Kwiatkowski How malaria has affected the human genome and what human genetics can teach us about malaria Am. J. Hum. Genet. 77 2005 171 192 (Pubitemid 41022702)
    • (2005) American Journal of Human Genetics , vol.77 , Issue.2 , pp. 171-192
    • Kwiatkowski, D.P.1
  • 68
    • 77955933649 scopus 로고    scopus 로고
    • Human pluripotent stem cells in drug discovery and predictive toxicology
    • D. Laustriat, J. Gide, and M. Peschanski Human pluripotent stem cells in drug discovery and predictive toxicology Biochem. Soc. Trans. 38 2010 1051 1057
    • (2010) Biochem. Soc. Trans. , vol.38 , pp. 1051-1057
    • Laustriat, D.1    Gide, J.2    Peschanski, M.3
  • 70
    • 2542418072 scopus 로고    scopus 로고
    • Investigating gene function using mouse models
    • DOI 10.1016/j.gde.2004.04.013, PII S0959437X04000590
    • D. Lee, and D.W. Threadgill Investigating gene function using mouse models Curr. Opin. Genet. Dev. 14 2004 246 252 (Pubitemid 38686928)
    • (2004) Current Opinion in Genetics and Development , vol.14 , Issue.3 , pp. 246-252
    • Lee, D.1    Threadgill, D.W.2
  • 71
    • 0842263993 scopus 로고    scopus 로고
    • Differential levels of diabetogenic stress in two new mouse models of obesity and type 2 diabetes
    • E.H. Leiter, and P.C. Reifsnyder Differential levels of diabetogenic stress in two new mouse models of obesity and type 2 diabetes Diabetes 53 2004 S4 S11
    • (2004) Diabetes , vol.53
    • Leiter, E.H.1    Reifsnyder, P.C.2
  • 74
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • G.R. Martin Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells Proc. Natl. Acad. Sci. U. S. A. 78 1981 7634 7638 (Pubitemid 12186197)
    • (1981) Proceedings of the National Academy of Sciences of the United States of America , vol.78 , Issue.12 , pp. 7634-7638
    • Martin, G.R.1
  • 79
    • 52549101134 scopus 로고    scopus 로고
    • Establishment of "the Gene Mine": A resource for rapid identification of complex trait genes
    • G. Morahan, L. Balmer, and D. Monley Establishment of "The Gene Mine": a resource for rapid identification of complex trait genes Mamm. Genome 19 2008 390 393
    • (2008) Mamm. Genome , vol.19 , pp. 390-393
    • Morahan, G.1    Balmer, L.2    Monley, D.3
  • 80
    • 77956615764 scopus 로고    scopus 로고
    • Human bone marrow and adipose tissue mesenchymal stem cells: A user's guide
    • F. Mosna, L. Sensebé, and M. Krampera Human bone marrow and adipose tissue mesenchymal stem cells: a user's guide Stem Cells Dev. 19 2010 1449 1470
    • (2010) Stem Cells Dev. , vol.19 , pp. 1449-1470
    • Mosna, F.1    Sensebé, L.2    Krampera, M.3
  • 82
    • 79952900523 scopus 로고    scopus 로고
    • Stem cells: Reprogramming's unintended consequences
    • M. Muers Stem cells: reprogramming's unintended consequences Nat. Rev. Genet. 12 2011 230
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 230
    • Muers, M.1
  • 84
    • 0037019331 scopus 로고    scopus 로고
    • Stem-cell competition
    • DOI 10.1038/418025a
    • S.H. Orkin, and S.J. Morrison Stem-cell competition Nature 418 2002 25 27 (Pubitemid 34742553)
    • (2002) Nature , vol.418 , Issue.6893 , pp. 25-27
    • Orkin, S.H.1    Morrison, S.J.2
  • 86
    • 0030950114 scopus 로고    scopus 로고
    • Lipid level and type alter stearoyl CoA desaturase mRNA abundance differently in mice with distinct susceptibilities to diet-influenced diseases
    • E.I. Park, E.A. Paisley, H.J. Mangian, D.A. Swartz, M.X. Wu, P.J. O'Morchoe, S.R. Behr, W.J. Visek, and J. Kaput Lipid level and type alter stearoyl CoA desaturase mRNA abundance differently in mice with distinct susceptibilities to diet-influenced diseases J. Nutr. 127 1997 566 573 (Pubitemid 27163621)
    • (1997) Journal of Nutrition , vol.127 , Issue.4 , pp. 566-573
    • Park, E.I.1    Paisley, E.A.2    Mangian, H.J.3    Swartz, D.A.4    Wu, M.5    O'Morchoe, P.J.6    Behr, S.R.7    Visek, W.J.8    Kaput, J.9
  • 87
    • 77953886372 scopus 로고    scopus 로고
    • An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus
    • C.J. Patel, J. Bhattacharya, and A.J. Butte An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus PLoS One 5 2010 e10746
    • (2010) PLoS One , vol.5 , pp. 10746
    • Patel, C.J.1    Bhattacharya, J.2    Butte, A.J.3
  • 89
    • 0030770463 scopus 로고    scopus 로고
    • Genetic dissection of obesity in polygenic animal models
    • DOI 10.1023/A:1025631813018
    • D. Pomp Genetic dissection of obesity in polygenic animal models Behav. Genet. 27 1997 285 306 (Pubitemid 27415167)
    • (1997) Behavior Genetics , vol.27 , Issue.4 , pp. 285-306
    • Pomp, D.1
  • 90
    • 67049143968 scopus 로고    scopus 로고
    • Algorithmic systems biology
    • C. Priami Algorithmic systems biology Communications of the ACH 52 2009 80 88
    • (2009) Communications of the ACH , vol.52 , pp. 80-88
    • Priami, C.1
  • 91
    • 1842684068 scopus 로고    scopus 로고
    • Genome sequence of the Brown Norway rat yields insights into mammalian evolution
    • Rat Genome Sequencing Project Consortium
    • Rat Genome Sequencing Project Consortium Genome sequence of the Brown Norway rat yields insights into mammalian evolution Nature 428 2004 493 521
    • (2004) Nature , vol.428 , pp. 493-521
  • 92
    • 0742306878 scopus 로고    scopus 로고
    • Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells 'hide out' in the bone marrow
    • DOI 10.1038/sj.leu.2403184
    • M.Z. Ratajczak, M. Kucia, R. Reca, M. Majka, A. Janowska-Wieczorek, and J. Ratajczak Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells 'hide out' in the bone marrow Leukemia 18 2004 29 40 (Pubitemid 38159436)
    • (2004) Leukemia , vol.18 , Issue.1 , pp. 29-40
    • Ratajczak, M.Z.1    Kucia, M.2    Reca, R.3    Majka, M.4    Janowska-Wieczorek, A.5    Ratajczak, J.6
  • 93
    • 0031639661 scopus 로고    scopus 로고
    • Use and misuse of population attributable fractions
    • B. Rockhill, B. Newman, and C. Weinberg Use and misuse of population attributable fractions Am. J. Public Health 88 1998 15 19
    • (1998) Am. J. Public Health , vol.88 , pp. 15-19
    • Rockhill, B.1    Newman, B.2    Weinberg, C.3
  • 94
    • 60149102748 scopus 로고    scopus 로고
    • Mouse models for the study of colon carcinogenesis
    • D.W. Rosenberg, C. Giardina, and T. Tanaka Mouse models for the study of colon carcinogenesis Carcinogenesis 30 2009 183 196
    • (2009) Carcinogenesis , vol.30 , pp. 183-196
    • Rosenberg, D.W.1    Giardina, C.2    Tanaka, T.3
  • 95
    • 77955633848 scopus 로고    scopus 로고
    • Toxicogenetics: Population-based testing of drug and chemical safety in mouse models
    • I. Rusyn, D.M. Gatti, T. Wiltshire, S.R. Kleeberger, and D.W. Threadgill Toxicogenetics: population-based testing of drug and chemical safety in mouse models Pharmacogenomics 11 2010 1127 1136
    • (2010) Pharmacogenomics , vol.11 , pp. 1127-1136
    • Rusyn, I.1    Gatti, D.M.2    Wiltshire, T.3    Kleeberger, S.R.4    Threadgill, D.W.5
  • 96
    • 80055017803 scopus 로고    scopus 로고
    • Toxicological testing: In vivo and in vitro models
    • R.C. Gupta, Elsevier Inc. New York, NY
    • M. Sachana, and A.J. Hargreaves Toxicological testing: in vivo and in vitro models R.C. Gupta, Veterinary Toxicology 2007 Elsevier Inc. New York, NY 51 66
    • (2007) Veterinary Toxicology , pp. 51-66
    • Sachana, M.1    Hargreaves, A.J.2
  • 97
    • 77950551326 scopus 로고    scopus 로고
    • Mesenchymal stromal cells: Current understanding and clinical status
    • H.K. Salem, and C. Thiemermann Mesenchymal stromal cells: current understanding and clinical status Stem Cells 31 2010 585 596
    • (2010) Stem Cells , vol.31 , pp. 585-596
    • Salem, H.K.1    Thiemermann, C.2
  • 99
    • 0026531139 scopus 로고
    • Overexpression of apolipoprotein e in transgenic mice: Marked reduction in plasma lipoproteins except high density lipoprotein and resistance against diet-induced hypercholesterolemia
    • H. Shimano, N. Yamada, M. Katsuki, M. Shimada, T. Gotoda, K. Harada, T. Murase, C. Fukazawa, F. Takaku, and Y. Yazaki Overexpression of apolipoprotein E in transgenic mice: marked reduction in plasma lipoproteins except high density lipoprotein and resistance against diet-induced hypercholesterolemia Proc. Natl. Acad. Sci. USA 89 1992 1750 1754
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1750-1754
    • Shimano, H.1    Yamada, N.2    Katsuki, M.3    Shimada, M.4    Gotoda, T.5    Harada, K.6    Murase, T.7    Fukazawa, C.8    Takaku, F.9    Yazaki, Y.10
  • 101
    • 0000461656 scopus 로고
    • The distribution of colony-forming cells among spleen colonies
    • L. Siminovitch, E.A. McCulloch, and J.E. Till The distribution of colony-forming cells among spleen colonies J. Cell. Physiol. 62 1963 327 336
    • (1963) J. Cell. Physiol. , vol.62 , pp. 327-336
    • Siminovitch, L.1    McCulloch, E.A.2    Till, J.E.3
  • 102
    • 0016177201 scopus 로고
    • Variation in the life-span of clones derived from human diploid cell strains
    • J.R. Smith, and L. Hayflick Variation in the life-span of clones derived from human diploid cell strains J. Cell Biol. 62 1974 48 53
    • (1974) J. Cell Biol. , vol.62 , pp. 48-53
    • Smith, J.R.1    Hayflick, L.2
  • 103
    • 79551591946 scopus 로고    scopus 로고
    • Tracking adult stem cells
    • H.J. Snippert, and H. Clevers Tracking adult stem cells EMBO Rep. 12 2011 113 122
    • (2011) EMBO Rep. , vol.12 , pp. 113-122
    • Snippert, H.J.1    Clevers, H.2
  • 104
    • 79955841697 scopus 로고    scopus 로고
    • Evaluating the heritability explained by known susceptibility variants: A survey of ten complex diseases
    • 10.1002/gepi.20579
    • H.C. So, A.H. Gui, S.S. Cherny, and P.C. Sham Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases Genet. Epidemiol 2011 10.1002/gepi.20579
    • (2011) Genet. Epidemiol
    • So, H.C.1    Gui, A.H.2    Cherny, S.S.3    Sham, P.C.4
  • 105
    • 44749089769 scopus 로고    scopus 로고
    • Successful validation of in vitro methods in toxicology by ZEBET, the National Centre for Alternatives in Germany at the BfR (Federal Institute for Risk Assessment)
    • H. Spielmann, B. Grune, M. Liebsch, A. Seiler, and R. Vogel Successful validation of in vitro methods in toxicology by ZEBET, the National Centre for Alternatives in Germany at the BfR (Federal Institute for Risk Assessment) Exp. Toxicol. Pathol. 60 2008 225 233
    • (2008) Exp. Toxicol. Pathol. , vol.60 , pp. 225-233
    • Spielmann, H.1    Grune, B.2    Liebsch, M.3    Seiler, A.4    Vogel, R.5
  • 106
    • 0030917962 scopus 로고    scopus 로고
    • The embryonic stem cell test (EST), an in vitro embryotoxicity test using two permanent mouse cell lines: 3T3 fibroblasts and embryonic stem cells
    • H. Spielmann, I. Pohl, B. Doring, M. Liebsch, and F. Moldenhauer The embryonic stem cell test (EST), an in vitro embryotoxicity test using two permanent mouse cell lines: 3T3 fibroblasts and embryonic stem cells In Vitro Toxicol. 10 1997 119 127
    • (1997) Vitro Toxicol. , vol.10 , pp. 119-127
    • Spielmann, H.1    Pohl, I.2    Doring, B.3    Liebsch, M.4    Moldenhauer, F.5
  • 107
    • 45549107755 scopus 로고    scopus 로고
    • Adult mesenchymal stromal stem cells for therapeutic applications
    • DOI 10.1080/13645700801969758, PII 791266981, Topic issue: Stem cell application in minimally invasive therapy
    • D. Spitkovsky, and J. Hescheler Adult mesenchymal stromal stem cells for therapeutic applications Minim. Invasive Ther. Allied Technol. 17 2008 79 90 (Pubitemid 351942702)
    • (2008) Minimally Invasive Therapy and Allied Technologies , vol.17 , Issue.2 , pp. 79-90
    • Spitkovsky, D.1    Hescheler, J.2
  • 108
    • 78649574963 scopus 로고    scopus 로고
    • Web-enabled and improved software tools and data are needed to measure nutrient intakes and physical activity for personalized health research
    • P.J. Stumbo, R. Weiss, J.W. Newman, J.A. Pennington, K.L. Tucker, P.L. Wiesenfeld, A.K. Illner, D.M. Klurfeld, and J. Kaput Web-enabled and improved software tools and data are needed to measure nutrient intakes and physical activity for personalized health research J. Nutr. 140 2010 2104 2115
    • (2010) J. Nutr. , vol.140 , pp. 2104-2115
    • Stumbo, P.J.1    Weiss, R.2    Newman, J.W.3    Pennington, J.A.4    Tucker, K.L.5    Wiesenfeld, P.L.6    Illner, A.K.7    Klurfeld, D.M.8    Kaput, J.9
  • 109
    • 36248966518 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
    • DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
    • K. Takahashi, K. Tanabe, M. Ohnuke, M. Narita, T. Ichisaka, K. Tomoda, and S. Yamanaka Induction of pluripotent stem cells from human adult fibroblasts by defined factors Cell 131 2007 861 872 (Pubitemid 350138099)
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 110
    • 33747195353 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
    • DOI 10.1016/j.cell.2006.07.024, PII S0092867406009767
    • K. Takahashi, and S. Yamanaka Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultured by defined factors Cell 126 2006 663 676 (Pubitemid 44233629)
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 111
    • 33644956003 scopus 로고    scopus 로고
    • High susceptibility of neural stem cells to methylmercury toxicity: Effects on cell survival and neuronal differentiation
    • C. Tamm, J. Duckworth, O. Hermanson, and S. Ceccatelli High susceptibility of neural stem cells to methylmercury toxicity: effects on cell survival and neuronal differentiation J. Neurochem. 97 2006 69 78
    • (2006) J. Neurochem. , vol.97 , pp. 69-78
    • Tamm, C.1    Duckworth, J.2    Hermanson, O.3    Ceccatelli, S.4
  • 112
    • 79958023074 scopus 로고    scopus 로고
    • Genetic study of gutter-shaped root (GSR) in AKXL RI mouse strains using QTL analysis
    • I. Tashima, K. Arita, and Y. Asada Genetic study of gutter-shaped root (GSR) in AKXL RI mouse strains using QTL analysis J. Oral Sci. 52 2010 213 220
    • (2010) J. Oral Sci. , vol.52 , pp. 213-220
    • Tashima, I.1    Arita, K.2    Asada, Y.3
  • 113
    • 77953546209 scopus 로고    scopus 로고
    • An abbreviated protocol for multilineage neural differentiation of murine embryonic stem cells and its perturbation by methyl mercury
    • P.T. Theunissen, S.H. Schulpen, D.A. van Dartel, S.A. Hermsen, F.J. van Schooten, and A.H. Piersma An abbreviated protocol for multilineage neural differentiation of murine embryonic stem cells and its perturbation by methyl mercury Reprod. Toxicol. 29 2010 383 392
    • (2010) Reprod. Toxicol. , vol.29 , pp. 383-392
    • Theunissen, P.T.1    Schulpen, S.H.2    Van Dartel, D.A.3    Hermsen, S.A.4    Van Schooten, F.J.5    Piersma, A.H.6
  • 114
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • J.A. Thomson, J. Itskovitz-Eldor, S.S. Shapiro, M.A. Waknitz, J.J. Swiergiel, V.S. Marshall, and J.M. Jones Embryonic stem cell lines derived from human blastocysts Science 282 1998 1145 1147 (Pubitemid 28516247)
    • (1998) Science , vol.282 , Issue.5391 , pp. 1145-1147
    • Thomson, J.A.1
  • 115
    • 0036215090 scopus 로고    scopus 로고
    • Genetic dissection of complex and quantitative traits: From fantasy to reality via a community effort
    • DOI 10.1007/s00335-001-4001-y
    • D.W. Threadgill, K.W. Hunter, and R.W. Williams Genetic dissection of complex and quantitative traits: from fantasy to reality via a community effort Mamm. Genome 13 2002 175 178 (Pubitemid 34299027)
    • (2002) Mammalian Genome , vol.13 , Issue.4 , pp. 175-178
    • Threadgill, D.W.1    Hunter, K.W.2    Williams, R.W.3
  • 116
    • 84956427297 scopus 로고
    • A direct measurement of the radiation sensitivity of normal mouse bone marrow cells
    • J.E. Till, and E.A. McCulloch A direct measurement of the radiation sensitivity of normal mouse bone marrow cells Radiat. Res. 14 1961 213 222
    • (1961) Radiat. Res. , vol.14 , pp. 213-222
    • Till, J.E.1    McCulloch, E.A.2
  • 118
    • 77956524118 scopus 로고    scopus 로고
    • Production of p53 gene knockout rats by homologous recombination in embryonic stem cells
    • C. Tong, P. Li, N.L. Wu, Y. Yan, and Q.L. Ying Production of p53 gene knockout rats by homologous recombination in embryonic stem cells Nature 467 2010 211 213
    • (2010) Nature , vol.467 , pp. 211-213
    • Tong, C.1    Li, P.2    Wu, N.L.3    Yan, Y.4    Ying, Q.L.5
  • 120
    • 0000673012 scopus 로고    scopus 로고
    • Guidelines for neurotoxicity risk assessment
    • U.s. Environmental Protection Agency
    • U.S. Environmental Protection Agency Guidelines for neurotoxicity risk assessment Fed. Regist. 63 1998 26926 26954
    • (1998) Fed. Regist. , vol.63 , pp. 26926-26954
  • 121
    • 68149164116 scopus 로고    scopus 로고
    • Challenging homeostasis to define biomarkers for nutrition related health
    • B. van Ommen, J. Keijer, S.G. Heil, and J. Kaput Challenging homeostasis to define biomarkers for nutrition related health Mol. Nutr. Food Res. 53 2009 795 804
    • (2009) Mol. Nutr. Food Res. , vol.53 , pp. 795-804
    • Van Ommen, B.1    Keijer, J.2    Heil, S.G.3    Kaput, J.4
  • 122
    • 77954731206 scopus 로고    scopus 로고
    • Missing heritability in genome-wide association study research
    • P. Vineis, and N. Pearce Missing heritability in genome-wide association study research Nat. Rev. Genet. 11 2010 589
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 589
    • Vineis, P.1    Pearce, N.2
  • 123
    • 77950022198 scopus 로고    scopus 로고
    • Challenges of using pluripotent stem cells for safety assessments of substances
    • K. Vojnits, and S. Bremer Challenges of using pluripotent stem cells for safety assessments of substances Toxicology 270 2010 10 17
    • (2010) Toxicology , vol.270 , pp. 10-17
    • Vojnits, K.1    Bremer, S.2
  • 124
    • 0016615948 scopus 로고
    • Cell models in the study of mechanisms of toxicity
    • J.R. Walton, and I.K. Buckley Cell models in the study of mechanisms of toxicity Agents Actions 5 1975 69 88
    • (1975) Agents Actions , vol.5 , pp. 69-88
    • Walton, J.R.1    Buckley, I.K.2
  • 125
    • 26844516176 scopus 로고    scopus 로고
    • Variability in gene expression and tumor formation within genetically homogeneous animal populations in bioassays
    • G.L. Wolff Variability in gene expression and tumor formation within genetically homogeneous animal populations in bioassays Fundam. Appl. Toxicol. 29 1996 176 184
    • (1996) Fundam. Appl. Toxicol. , vol.29 , pp. 176-184
    • Wolff, G.L.1
  • 126
    • 0035376419 scopus 로고    scopus 로고
    • Gene Expression in Atherosclerotic Lesion of ApoE Deficient Mice
    • D.M. Wuttge, A. Sirsjö, P. Eriksson, and S. Stemme Gene expression in atherosclerotic lesion of ApoE deficient mice Mol. Med. 7 2001 383 392 (Pubitemid 33701973)
    • (2001) Molecular Medicine , vol.7 , Issue.6 , pp. 383-392
    • Wuttge, D.M.1    Sirsjo, A.2    Eriksson, P.3    Stemme, S.4
  • 127
    • 17544371811 scopus 로고    scopus 로고
    • Alternative splicing of the human cholesteryl ester transfer protein gene in transgenic mice: Exon exclusion modulates gene expression in response to dietary or developmental change
    • DOI 10.1074/jbc.271.21.12603
    • T.P. Yang, L.B. Agellon, A. Walsh, J.L. Breslow, and A.R. Tall Alternative splicing of the human cholesteryl ester transfer protein gene in transgenic mice. Exon exclusion modulates gene expression in response to dietary or developmental change J. Biol. Chem. 271 1996 12603 12609 (Pubitemid 26160935)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.21 , pp. 12603-12609
    • Yang, T.-P.1    Agellon, L.B.2    Walsh, A.3    Breslow, J.L.4    Tall, A.R.5
  • 129
    • 70349745413 scopus 로고    scopus 로고
    • Novel biological insights through metabolomics and 13C-flux analysis
    • N. Zamboni, and U. Sauer Novel biological insights through metabolomics and 13C-flux analysis Curr. Opin. Microbiol. 12 2009 553 558
    • (2009) Curr. Opin. Microbiol. , vol.12 , pp. 553-558
    • Zamboni, N.1    Sauer, U.2
  • 130
    • 0026592806 scopus 로고
    • Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein e
    • S.H. Zhang, R.L. Reddick, J.A. Piedrahita, and N. Maeda Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E Science 258 1992 468 471
    • (1992) Science , vol.258 , pp. 468-471
    • Zhang, S.H.1    Reddick, R.L.2    Piedrahita, J.A.3    Maeda, N.4
  • 131
    • 79952898021 scopus 로고    scopus 로고
    • Investigating monogenic and complex diseases with pluripotent stem cells
    • H. Zhu, M.W. Lensch, P. Cahan, and G.Q. Daley Investigating monogenic and complex diseases with pluripotent stem cells Nat. Rev. Genet. 12 2011 266 275
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 266-275
    • Zhu, H.1    Lensch, M.W.2    Cahan, P.3    Daley, G.Q.4
  • 132
    • 0842264755 scopus 로고    scopus 로고
    • Molecular multiple endpoint embryonic stem cell test - A possible approach to test for the teratogenic potential of compounds
    • DOI 10.1016/j.taap.2003.09.019
    • N.I. zur Nieden, G. Kempka, and H.J. Ahr Molecular multiple endpoint embryonic stem cell test - a possible approach to test for the teratogenic potential of compounds Toxicol. Appl. Pharmacol. 194 2004 257 269 (Pubitemid 38175288)
    • (2004) Toxicology and Applied Pharmacology , vol.194 , Issue.3 , pp. 257-269
    • Zur Nieden, N.I.1    Kempka, G.2    Ahr, H.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.