메뉴 건너뛰기




Volumn 85, Issue 20, 2011, Pages 10617-10626

Recombination-mediated changes in coreceptor usage confer an augmented pathogenic phenotype in a nonhuman primate model of HIV-1-induced AIDS

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; VIRUS RNA;

EID: 80054967648     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.05010-11     Document Type: Article
Times cited : (7)

References (60)
  • 1
    • 0033012398 scopus 로고    scopus 로고
    • Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease
    • Berger, E. A., P. M. Murphy, and J. M. Farber. 1999. Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease. Annu. Rev. Immunol. 17:657-700.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 657-700
    • Berger, E.A.1    Murphy, P.M.2    Farber, J.M.3
  • 2
    • 34249808840 scopus 로고    scopus 로고
    • Unique pathology in simian immunodeficiency virus-infected rapid progressor macaques is consistent with a pathogenesis distinct from that of classical AIDS
    • Brown, C. R., et al. 2007. Unique pathology in simian immunodeficiency virus-infected rapid progressor macaques is consistent with a pathogenesis distinct from that of classical AIDS. J. Virol. 81:5594-5606.
    • (2007) J. Virol. , vol.81 , pp. 5594-5606
    • Brown, C.R.1
  • 3
    • 22544456536 scopus 로고    scopus 로고
    • Molecular and clinical epidemiology of CXCR4-using HIV-1 in a large population of antiretroviral-naive individuals
    • Brumme, Z. L., et al. 2005. Molecular and clinical epidemiology of CXCR4-using HIV-1 in a large population of antiretroviral-naive individuals. J. Infect. Dis. 192:466-474.
    • (2005) J. Infect. Dis. , vol.192 , pp. 466-474
    • Brumme, Z.L.1
  • 4
    • 33144487829 scopus 로고    scopus 로고
    • Extensive recombination among human immunodeficiency virus type 1 quasispecies makes an important contribution to viral diversity in individual patients
    • Charpentier, C., T. Nora, O. Tenaillon, F. Clavel, and A. J. Hance. 2006. Extensive recombination among human immunodeficiency virus type 1 quasispecies makes an important contribution to viral diversity in individual patients. J. Virol. 80:2472-2482.
    • (2006) J. Virol. , vol.80 , pp. 2472-2482
    • Charpentier, C.1    Nora, T.2    Tenaillon, O.3    Clavel, F.4    Hance, A.J.5
  • 5
    • 0033809610 scopus 로고    scopus 로고
    • Identification of gp120 regions targeted by a highly potent neutralizing antiserum elicited in a chimpanzee inoculated with a primary human immunodeficiency virus type 1 isolate
    • Cho, M. W., M. K. Lee, C. H. Chen, T. Matthews, and M. A. Martin. 2000. Identification of gp120 regions targeted by a highly potent neutralizing antiserum elicited in a chimpanzee inoculated with a primary human immunodeficiency virus type 1 isolate. J. Virol. 74:9749-9754.
    • (2000) J. Virol. , vol.74 , pp. 9749-9754
    • Cho, M.W.1    Lee, M.K.2    Chen, C.H.3    Matthews, T.4    Martin, M.A.5
  • 6
    • 0031575431 scopus 로고    scopus 로고
    • Change in coreceptor use correlates with disease progression in HIV-1-infected individuals
    • Connor, R. I., K. E. Sheridan, D. Ceradini, S. Choe, and N. R. Landau. 1997. Change in coreceptor use correlates with disease progression in HIV-1-infected individuals. J. Exp. Med. 185:621-628.
    • (1997) J. Exp. Med. , vol.185 , pp. 621-628
    • Connor, R.I.1    Sheridan, K.E.2    Ceradini, D.3    Choe, S.4    Landau, N.R.5
  • 7
    • 0001633495 scopus 로고    scopus 로고
    • Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene
    • Dean, M., et al. 1996. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Science 273:1856-1862.
    • (1996) Science , vol.273 , pp. 1856-1862
    • Dean, M.1
  • 8
    • 0026702003 scopus 로고
    • Minimal requirements for the human immunodeficiency virus type 1 V3 domain to support the syncytium-inducing phenotype: analysis by single amino acid substitution
    • De Jong, J. J., A. De Ronde, W. Keulen, M. Tersmette, and J. Goudsmit. 1992. Minimal requirements for the human immunodeficiency virus type 1 V3 domain to support the syncytium-inducing phenotype: analysis by single amino acid substitution. J. Virol. 66:6777-6780.
    • (1992) J. Virol. , vol.66 , pp. 6777-6780
    • De Jong, J.J.1    De Ronde, A.2    Keulen, W.3    Tersmette, M.4    Goudsmit, J.5
  • 9
    • 15044339793 scopus 로고    scopus 로고
    • R5 to X4 switch of the predominant HIV-1 population in cellular reservoirs during effective highly active antiretroviral therapy
    • Delobel, P., et al. 2005. R5 to X4 switch of the predominant HIV-1 population in cellular reservoirs during effective highly active antiretroviral therapy. J. Acquir. Immune Defic. Syndr. 38:382-392.
    • (2005) J. Acquir. Immune Defic. Syndr. , vol.38 , pp. 382-392
    • Delobel, P.1
  • 10
    • 0033942484 scopus 로고    scopus 로고
    • Short- and long-term clinical outcomes in rhesus monkeys inoculated with a highly pathogenic chimeric simian/human immunodeficiency virus
    • Endo, Y., et al. 2000. Short- and long-term clinical outcomes in rhesus monkeys inoculated with a highly pathogenic chimeric simian/human immunodeficiency virus. J. Virol. 74:6935-6945.
    • (2000) J. Virol. , vol.74 , pp. 6935-6945
    • Endo, Y.1
  • 11
    • 0026606727 scopus 로고
    • Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule
    • Fouchier, R. A., et al. 1992. Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule. J. Virol. 66:3183-3187.
    • (1992) J. Virol. , vol.66 , pp. 3183-3187
    • Fouchier, R.A.1
  • 12
    • 34547731884 scopus 로고    scopus 로고
    • Coreceptor switch in R5-tropic simian/human immunodeficiency virus-infected macaques
    • Ho, S. H., et al. 2007. Coreceptor switch in R5-tropic simian/human immunodeficiency virus-infected macaques. J. Virol. 81:8621-8633.
    • (2007) J. Virol. , vol.81 , pp. 8621-8633
    • Ho, S.H.1
  • 13
    • 43949094156 scopus 로고    scopus 로고
    • Different mutational pathways to CXCR4 coreceptor switch of CCR5-using simian-human immunodeficiency virus
    • Ho, S. H., N. Trunova, A. Gettie, J. Blanchard, and C. Cheng-Mayer. 2008. Different mutational pathways to CXCR4 coreceptor switch of CCR5-using simian-human immunodeficiency virus. J. Virol. 82:5653-5656.
    • (2008) J. Virol. , vol.82 , pp. 5653-5656
    • Ho, S.H.1    Trunova, N.2    Gettie, A.3    Blanchard, J.4    Cheng-Mayer, C.5
  • 14
    • 43949118440 scopus 로고    scopus 로고
    • Coreceptor tropism can be influenced by amino acid substitutions in the gp41 transmembrane subunit of human immunodeficiency virus type 1 envelope protein
    • Huang, W., et al. 2008. Coreceptor tropism can be influenced by amino acid substitutions in the gp41 transmembrane subunit of human immunodeficiency virus type 1 envelope protein. J. Virol. 82:5584-5593.
    • (2008) J. Virol. , vol.82 , pp. 5584-5593
    • Huang, W.1
  • 15
    • 70349213751 scopus 로고    scopus 로고
    • Characterization of human immunodeficiency virus type 1 populations containing CXCR4-using variants from recently infected individuals
    • Huang, W., et al. 2009. Characterization of human immunodeficiency virus type 1 populations containing CXCR4-using variants from recently infected individuals. AIDS Res. Hum. Retrovir. 25:795-802.
    • (2009) AIDS Res. Hum. Retrovir. , vol.25 , pp. 795-802
    • Huang, W.1
  • 16
    • 33749039498 scopus 로고    scopus 로고
    • Prevalence of CXCR4 tropism among antiretroviraltreated HIV-1-infected patients with detectable viremia
    • Hunt, P. W., et al. 2006. Prevalence of CXCR4 tropism among antiretroviraltreated HIV-1-infected patients with detectable viremia. J. Infect. Dis. 194: 926-930.
    • (2006) J. Infect. Dis. , vol.194 , pp. 926-930
    • Hunt, P.W.1
  • 17
    • 10744233668 scopus 로고    scopus 로고
    • Macrophage-tropic simian/human immunodeficiency virus chimeras use CXCR4, not CCR5, for infections of rhesus macaque peripheral blood mononuclear cells and alveolar macrophages
    • Igarashi, T., et al. 2003. Macrophage-tropic simian/human immunodeficiency virus chimeras use CXCR4, not CCR5, for infections of rhesus macaque peripheral blood mononuclear cells and alveolar macrophages. J. Virol. 77:13042-13052.
    • (2003) J. Virol. , vol.77 , pp. 13042-13052
    • Igarashi, T.1
  • 18
    • 34648813029 scopus 로고    scopus 로고
    • Although macrophage-tropic simian/human immunodeficiency viruses can exhibit a range of pathogenic phenotypes, a majority of isolates induce no clinical disease in immunocompetent macaques
    • Igarashi, T., et al. 2007. Although macrophage-tropic simian/human immunodeficiency viruses can exhibit a range of pathogenic phenotypes, a majority of isolates induce no clinical disease in immunocompetent macaques. J. Virol. 81:10669-10679.
    • (2007) J. Virol. , vol.81 , pp. 10669-10679
    • Igarashi, T.1
  • 19
    • 13044285440 scopus 로고    scopus 로고
    • Emergence of a highly pathogenic simian/human immunodeficiency virus in a rhesus macaque treated with anti-CD8 MAb during a primary infection with a nonpathogenic virus
    • Igarashi, T., et al. 1999. Emergence of a highly pathogenic simian/human immunodeficiency virus in a rhesus macaque treated with anti-CD8 MAb during a primary infection with a nonpathogenic virus. Proc. Natl. Acad. Sci. U. S. A. 96:14049-14054.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 14049-14054
    • Igarashi, T.1
  • 20
    • 0141566346 scopus 로고    scopus 로고
    • Early control of highly pathogenic simian immunodeficiency virus/human immunodeficiency virus chimeric virus infections in rhesus monkeys usually results in long-lasting asymptomatic clinical outcomes
    • Igarashi, T., et al. 2003. Early control of highly pathogenic simian immunodeficiency virus/human immunodeficiency virus chimeric virus infections in rhesus monkeys usually results in long-lasting asymptomatic clinical outcomes. J. Virol. 77:10829-10840.
    • (2003) J. Virol. , vol.77 , pp. 10829-10840
    • Igarashi, T.1
  • 21
    • 10744231634 scopus 로고    scopus 로고
    • Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 env V3 loop sequences
    • Jensen, M. A., et al. 2003. Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 env V3 loop sequences. J. Virol. 77:13376-13388.
    • (2003) J. Virol. , vol.77 , pp. 13376-13388
    • Jensen, M.A.1
  • 22
    • 0027955291 scopus 로고
    • MT-2 cell tropism as prognostic marker for disease progression in human immunodeficiency virus type 1 infection
    • Karlsson, A., K. Parsmyr, E. Sandstrom, E. M. Fenyo, and J. Albert. 1994. MT-2 cell tropism as prognostic marker for disease progression in human immunodeficiency virus type 1 infection. J. Clin. Microbiol. 32:364-370.
    • (1994) J. Clin. Microbiol. , vol.32 , pp. 364-370
    • Karlsson, A.1    Parsmyr, K.2    Sandstrom, E.3    Fenyo, E.M.4    Albert, J.5
  • 23
    • 44649102135 scopus 로고    scopus 로고
    • Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
    • Keele, B. F., et al. 2008. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc. Natl. Acad. Sci. U. S. A. 105:7552-7557.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 7552-7557
    • Keele, B.F.1
  • 24
    • 0242331608 scopus 로고    scopus 로고
    • HIV-1 in genital tract and plasma of women: compartmentalization of viral sequences, coreceptor usage, and glycosylation
    • Kemal, K. S., et al. 2003. HIV-1 in genital tract and plasma of women: compartmentalization of viral sequences, coreceptor usage, and glycosylation. Proc. Natl. Acad. Sci. U. S. A. 100:12972-12977.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 12972-12977
    • Kemal, K.S.1
  • 25
    • 1842328057 scopus 로고    scopus 로고
    • Simian immunodeficiency virus variants with differential T-cell and macrophage tropism use CCR5 and an unidentified cofactor expressed in CEMx174 cells for efficient entry
    • Kirchhoff, F., et al. 1997. Simian immunodeficiency virus variants with differential T-cell and macrophage tropism use CCR5 and an unidentified cofactor expressed in CEMx174 cells for efficient entry. J. Virol. 71:6509-6516.
    • (1997) J. Virol. , vol.71 , pp. 6509-6516
    • Kirchhoff, F.1
  • 26
    • 0036838722 scopus 로고    scopus 로고
    • Selection for human immunodeficiency virus type 1 recombinants in a patient with rapid progression to AIDS
    • Liu, S. L., et al. 2002. Selection for human immunodeficiency virus type 1 recombinants in a patient with rapid progression to AIDS. J. Virol. 76: 10674-10684.
    • (2002) J. Virol. , vol.76 , pp. 10674-10684
    • Liu, S.L.1
  • 27
    • 0034820907 scopus 로고    scopus 로고
    • Identification and comparison of eleven rhesus macaque chemokine receptors
    • Margulies, B. J., D. A. Hauer, and J. E. Clements. 2001. Identification and comparison of eleven rhesus macaque chemokine receptors. AIDS Res. Hum. Retrovir. 17:981-986.
    • (2001) AIDS Res. Hum. Retrovir. , vol.17 , pp. 981-986
    • Margulies, B.J.1    Hauer, D.A.2    Clements, J.E.3
  • 28
    • 33947381341 scopus 로고    scopus 로고
    • Frequent intrapatient recombination between human immunodeficiency virus type 1 R5 and X4 envelopes: implications for coreceptor switch
    • Mild, M., J. Esbjornsson, E. M. Fenyo, and P. Medstrand. 2007. Frequent intrapatient recombination between human immunodeficiency virus type 1 R5 and X4 envelopes: implications for coreceptor switch. J. Virol. 81:3369-3376.
    • (2007) J. Virol. , vol.81 , pp. 3369-3376
    • Mild, M.1    Esbjornsson, J.2    Fenyo, E.M.3    Medstrand, P.4
  • 29
    • 14844333093 scopus 로고    scopus 로고
    • Epidemiology and predictive factors for chemokine receptor use in HIV-1 infection
    • Moyle, G. J., et al. 2005. Epidemiology and predictive factors for chemokine receptor use in HIV-1 infection. J. Infect. Dis. 191:866-872.
    • (2005) J. Infect. Dis. , vol.191 , pp. 866-872
    • Moyle, G.J.1
  • 30
    • 0003633755 scopus 로고
    • National Institutes of Health. Department of Health and Human Services publication no. NIH 85-23. National Institutes of Health, Bethesda, MD
    • National Institutes of Health. 1985. Guide for the care and use of laboratory animals. Department of Health and Human Services publication no. NIH 85-23. National Institutes of Health, Bethesda, MD.
    • (1985) Guide for the care and use of laboratory animals
  • 31
    • 20344375938 scopus 로고    scopus 로고
    • + T cells are massively infected and eliminated by X4-tropic simian-human immunodeficiency viruses in macaques
    • + T cells are massively infected and eliminated by X4-tropic simian-human immunodeficiency viruses in macaques. Proc. Natl. Acad. Sci. U. S. A. 102:8000-8005.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 8000-8005
    • Nishimura, Y.1
  • 32
    • 33846061212 scopus 로고    scopus 로고
    • + T-cell depletion during long-term progression to AIDS in simian immunodeficiency virus-infected macaques
    • + T-cell depletion during long-term progression to AIDS in simian immunodeficiency virus-infected macaques. J. Virol. 81:893-902.
    • (2007) J. Virol. , vol.81 , pp. 893-902
    • Nishimura, Y.1
  • 33
    • 4344592775 scopus 로고    scopus 로고
    • + T cell subsets in rhesus monkeys, explaining their divergent clinical courses
    • + T cell subsets in rhesus monkeys, explaining their divergent clinical courses. Proc. Natl. Acad. Sci. U. S. A. 101:12324-12329.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 12324-12329
    • Nishimura, Y.1
  • 34
    • 77950787447 scopus 로고    scopus 로고
    • Generation of the pathogenic R5-tropic simian/ human immunodeficiency virus SHIVAD8 by serial passaging in rhesus macaques
    • Nishimura, Y., et al. 2010. Generation of the pathogenic R5-tropic simian/ human immunodeficiency virus SHIVAD8 by serial passaging in rhesus macaques. J. Virol. 84:4769-4781.
    • (2010) J. Virol. , vol.84 , pp. 4769-4781
    • Nishimura, Y.1
  • 35
    • 34447249033 scopus 로고    scopus 로고
    • Contribution of recombination to the evolution of human immunodeficiency viruses expressing resistance to antiretroviral treatment
    • Nora, T., et al. 2007. Contribution of recombination to the evolution of human immunodeficiency viruses expressing resistance to antiretroviral treatment. J. Virol. 81:7620-7628.
    • (2007) J. Virol. , vol.81 , pp. 7620-7628
    • Nora, T.1
  • 36
    • 0033780046 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding
    • O'Doherty, U., W. J. Swiggard, and M. H. Malim. 2000. Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding. J. Virol. 74:10074-10080.
    • (2000) J. Virol. , vol.74 , pp. 10074-10080
    • O'Doherty, U.1    Swiggard, W.J.2    Malim, M.H.3
  • 37
    • 9244220630 scopus 로고    scopus 로고
    • + memory T cells in rapidly progressive simian immunodeficiency virus infection
    • + memory T cells in rapidly progressive simian immunodeficiency virus infection. J. Exp. Med. 200:1299-1314.
    • (2004) J. Exp. Med. , vol.200 , pp. 1299-1314
    • Picker, L.J.1
  • 38
    • 0036135578 scopus 로고    scopus 로고
    • Development and homeostasis of T cell memory in rhesus macaque
    • Pitcher, C. J., et al. 2002. Development and homeostasis of T cell memory in rhesus macaque. J. Immunol. 168:29-43.
    • (2002) J. Immunol. , vol.168 , pp. 29-43
    • Pitcher, C.J.1
  • 39
    • 0035918220 scopus 로고    scopus 로고
    • N-linked glycosylation of the HIV type-1 gp120 envelope glycoprotein as a major determinant of CCR5 and CXCR4 coreceptor utilization
    • Pollakis, G., et al. 2001. N-linked glycosylation of the HIV type-1 gp120 envelope glycoprotein as a major determinant of CCR5 and CXCR4 coreceptor utilization. J. Biol. Chem. 276:13433-13441.
    • (2001) J. Biol. Chem. , vol.276 , pp. 13433-13441
    • Pollakis, G.1
  • 40
    • 20344399376 scopus 로고    scopus 로고
    • The HIV coreceptor switch: a population dynamical perspective
    • Regoes, R. R., and S. Bonhoeffer. 2005. The HIV coreceptor switch: a population dynamical perspective. Trends Microbiol. 13:269-277.
    • (2005) Trends Microbiol , vol.13 , pp. 269-277
    • Regoes, R.R.1    Bonhoeffer, S.2
  • 41
    • 0029794529 scopus 로고    scopus 로고
    • A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys
    • Reimann, K. A., et al. 1996. A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys. J. Virol. 70:6922-6928.
    • (1996) J. Virol. , vol.70 , pp. 6922-6928
    • Reimann, K.A.1
  • 42
    • 72849151472 scopus 로고    scopus 로고
    • Different tempo and anatomic location of dualtropic and X4 virus emergence in a model of R5 simian-human immunodeficiency virus infection
    • Ren, W., et al. 2010. Different tempo and anatomic location of dualtropic and X4 virus emergence in a model of R5 simian-human immunodeficiency virus infection. J. Virol. 84:340-351.
    • (2010) J. Virol. , vol.84 , pp. 340-351
    • Ren, W.1
  • 43
    • 0035884899 scopus 로고    scopus 로고
    • Improved success of phenotype prediction of the human immunodeficiency virus type 1 from envelope variable loop 3 sequence using neural networks
    • Resch, W., N. Hoffman, and R. Swanstrom. 2001. Improved success of phenotype prediction of the human immunodeficiency virus type 1 from envelope variable loop 3 sequence using neural networks. Virology 288: 51-62.
    • (2001) Virology , vol.288 , pp. 51-62
    • Resch, W.1    Hoffman, N.2    Swanstrom, R.3
  • 44
    • 0028027078 scopus 로고
    • The impact of the syncytiuminducing phenotype of human immunodeficiency virus on disease progression
    • Richman, D. D., and S. A. Bozzette. 1994. The impact of the syncytiuminducing phenotype of human immunodeficiency virus on disease progression. J. Infect. Dis. 169:968-974.
    • (1994) J. Infect. Dis. , vol.169 , pp. 968-974
    • Richman, D.D.1    Bozzette, S.A.2
  • 45
    • 0034615972 scopus 로고    scopus 로고
    • HIV-1 nomenclature proposal
    • Robertson, D. L., et al. 2000. HIV-1 nomenclature proposal. Science 288: 55-56.
    • (2000) Science , vol.288 , pp. 55-56
    • Robertson, D.L.1
  • 46
    • 2342625375 scopus 로고    scopus 로고
    • Induction of disease by a molecularly cloned highly pathogenic simian immunodeficiency virus/human immunodeficiency virus chimera is multigenic
    • Sadjadpour, R., et al. 2004. Induction of disease by a molecularly cloned highly pathogenic simian immunodeficiency virus/human immunodeficiency virus chimera is multigenic. J. Virol. 78:5513-5519.
    • (2004) J. Virol. , vol.78 , pp. 5513-5519
    • Sadjadpour, R.1
  • 47
    • 61849171106 scopus 로고    scopus 로고
    • Selection of HIV variants with signature genotypic characteristics during heterosexual transmission
    • Sagar, M., et al. 2009. Selection of HIV variants with signature genotypic characteristics during heterosexual transmission. J. Infect. Dis. 199:580-589.
    • (2009) J. Infect. Dis. , vol.199 , pp. 580-589
    • Sagar, M.1
  • 48
    • 41949124934 scopus 로고    scopus 로고
    • Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencing
    • Salazar-Gonzalez, J. F., et al. 2008. Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencing. J. Virol. 82:3952-3970.
    • (2008) J. Virol. , vol.82 , pp. 3952-3970
    • Salazar-Gonzalez, J.F.1
  • 49
    • 66049139947 scopus 로고    scopus 로고
    • Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection
    • Salazar-Gonzalez, J. F., et al. 2009. Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. J. Exp. Med. 206:1273-1289.
    • (2009) J. Exp. Med. , vol.206 , pp. 1273-1289
    • Salazar-Gonzalez, J.F.1
  • 50
    • 16044373004 scopus 로고    scopus 로고
    • Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
    • Samson, M., et al. 1996. Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 382:722-725.
    • (1996) Nature , vol.382 , pp. 722-725
    • Samson, M.1
  • 51
    • 0026600926 scopus 로고
    • Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population
    • Schuitemaker, H., et al. 1992. Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population. J. Virol. 66:1354-1360.
    • (1992) J. Virol. , vol.66 , pp. 1354-1360
    • Schuitemaker, H.1
  • 52
    • 0030855058 scopus 로고    scopus 로고
    • Infection and pathogenicity of chimeric simianhuman immunodeficiency viruses in macaques: determinants of high virus loads and CD4 cell killing
    • Shibata, R., et al. 1997. Infection and pathogenicity of chimeric simianhuman immunodeficiency viruses in macaques: determinants of high virus loads and CD4 cell killing. J. Infect. Dis. 176:362-373.
    • (1997) J. Infect. Dis. , vol.176 , pp. 362-373
    • Shibata, R.1
  • 53
    • 0025652444 scopus 로고
    • Interactions between HIV and the host immune system in the pathogenesis of AIDS
    • Tersmette, M., and F. Miedema. 1990. Interactions between HIV and the host immune system in the pathogenesis of AIDS. AIDS 4(Suppl. 1):S57-S66.
    • (1990) AIDS , vol.4 , Issue.SUPPL. 1
    • Tersmette, M.1    Miedema, F.2
  • 54
    • 0141568790 scopus 로고    scopus 로고
    • Evolution of R5 and X4 human immunodeficiency virus type 1 gag sequences in vivo: evidence for recombination
    • van Rij, R. P., M. Worobey, J. A. Visser, and H. Schuitemaker. 2003. Evolution of R5 and X4 human immunodeficiency virus type 1 gag sequences in vivo: evidence for recombination. Virology 314:451-459.
    • (2003) Virology , vol.314 , pp. 451-459
    • van Rij, R.P.1    Worobey, M.2    Visser, J.A.3    Schuitemaker, H.4
  • 55
    • 0028091755 scopus 로고
    • Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission
    • van't Wout, A. B., et al. 1994. Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission. J. Clin. Invest. 94:2060-2067.
    • (1994) J. Clin. Invest. , vol.94 , pp. 2060-2067
    • van't Wout, A.B.1
  • 56
    • 33846932573 scopus 로고    scopus 로고
    • HIV type 1 chemokine coreceptor use among antiretroviral-experienced patients screened for a clinical trial of a CCR5 inhibitor: AIDS Clinical Trial Group A5211
    • Wilkin, T. J., et al. 2007. HIV type 1 chemokine coreceptor use among antiretroviral-experienced patients screened for a clinical trial of a CCR5 inhibitor: AIDS Clinical Trial Group A5211. Clin. Infect. Dis. 44:591-595.
    • (2007) Clin. Infect. Dis. , vol.44 , pp. 591-595
    • Wilkin, T.J.1
  • 57
    • 76449108010 scopus 로고    scopus 로고
    • Neutralizing antibody titers conferring protection to macaques from a simian/ human immunodeficiency virus challenge using the TZM-bl assay
    • Willey, R., M. C. Nason, Y. Nishimura, D. A. Follmann, and M. A. Martin. Neutralizing antibody titers conferring protection to macaques from a simian/ human immunodeficiency virus challenge using the TZM-bl assay. AIDS Res. Hum. Retrovir. 26:89-98.
    • AIDS Res. Hum. Retrovir. , vol.26 , pp. 89-98
    • Willey, R.1    Nason, M.C.2    Nishimura, Y.3    Follmann, D.A.4    Martin, M.A.5
  • 58
    • 0023930757 scopus 로고
    • In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity
    • Willey, R. L., et al. 1988. In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity. J. Virol. 62:139-147.
    • (1988) J. Virol. , vol.62 , pp. 139-147
    • Willey, R.L.1
  • 59
    • 0033927570 scopus 로고    scopus 로고
    • Use of inhibitors to evaluate coreceptor usage by simian and simian/human immunodeficiency viruses and human immunodeficiency virus type 2 in primary cells
    • Zhang, Y., et al. 2000. Use of inhibitors to evaluate coreceptor usage by simian and simian/human immunodeficiency viruses and human immunodeficiency virus type 2 in primary cells. J. Virol. 74:6893-6910.
    • (2000) J. Virol. , vol.74 , pp. 6893-6910
    • Zhang, Y.1
  • 60
    • 0027422278 scopus 로고
    • Genotypic and phenotypic characterization of HIV-1 patients with primary infection
    • Zhu, T., et al. 1993. Genotypic and phenotypic characterization of HIV-1 patients with primary infection. Science 261:1179-1181.
    • (1993) Science , vol.261 , pp. 1179-1181
    • Zhu, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.